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1. 发明申请

WO2004002559A1 METHOD AND PACKAGING FOR PRESSURIZED CONTAINERS 审中-公开
标题翻译：加压容器的方法和包装
公开(公告)号：WO2004002559A1
公开(公告)日：2004-01-08
申请号：PCT/GB2003/002558
申请日：2003-06-13
申请人： AVENTIS PHARMA LIMITED , BARKER, Frank, Colin
发明人： BARKER, Frank, Colin
IPC分类号： A61M15/00
CPC分类号： B65D81/268 , A61M15/009 , A61M2202/062 , A61M2209/06 , B65D75/26
摘要： A method for maintaining the enclosed volume of a sealed package at about ambient pressure, wherein the package contains a pressurized container comprising a drug, and an HFA (hydrofluoroalkane) propellant selected from the group consisting of HFA 134a and HFA p227, or a mixture thereof; wherein the method comprises the steps of (1) positioning an effective amount of a HFA adsorbent material, and said pressurized container, within a sealable package; (2) sealing the package so that the pressurized container and adsorbent are in an enclosed volume within the package at a pressure equal to about ambient pressure; and (3) adsorbing any leakage of the HFA propellant into the HFA adsorbent material so as to maintain the enclosed volume at about ambient pressure.
摘要翻译：一种用于在约环境压力下保持密封包装的封闭体积的方法，其中所述包装包含包含药物的加压容器和选自HFA134a和HFA p227的HFA（氢氟烷烃）推进剂，或其混合物 ; 其中所述方法包括以下步骤：（1）将有效量的HFA吸附剂材料和所述加压容器定位在可密封包装内; （2）密封包装，使得加压容器和吸附剂在等于大约环境压力的压力下处于封装内的封闭体积; 和（3）将HFA推进剂的任何泄漏吸附到HFA吸附剂材料中，以将封闭体积保持在大约环境压力。

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