专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2006037049A3 APPLICATION OF A COATING ON A MEDICAL DEVICE 审中-公开
标题翻译：涂料在医疗器械上的应用
公开(公告)号：WO2006037049A3
公开(公告)日：2006-08-31
申请号：PCT/US2005034836
申请日：2005-09-28
申请人： ATRIUM MEDICAL CORP , LABRECQUE ROGER , MOODIE GEOFFREY , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , CONROY SUZANNE , SUNTER BRIAN , HENRICH GEORGETTE
发明人： LABRECQUE ROGER , MOODIE GEOFFREY , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , CONROY SUZANNE , SUNTER BRIAN , HENRICH GEORGETTE
IPC分类号： B05C13/02 , A61B1/32 , A61F2/82 , A61F2/86 , A61M25/00 , B05D5/08
CPC分类号： A61L31/08 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61K47/10 , A61K47/22 , A61K47/44 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/22 , A61L2300/416 , A61L2300/428 , A61L2300/45 , A61L2300/606 , A61L2300/802 , A61L2420/02 , A61M25/0009 , A61M25/0045
摘要： Methods and devices (300) for the provision of a coating on an implantable medical device (310). The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The methods and devices provide a coating having improved uniformity and coverage which in turn allow for greater control of the amount and dosage of the coating.
摘要翻译：用于在可植入医疗装置（310）上提供涂层的方法和装置（300）。涂层包括生物吸收载体组分。除了生物可吸收载体组分之外，还可以提供治疗剂成分。所述方法和装置提供了具有改进的均匀性和覆盖度的涂层，其又允许更大程度地控制涂层的量和剂量。

2. 发明申请

WO2006036983A3 PRE-DRIED DRUG DELIVERY COATING FOR USE WITH A STENT 审中-公开
标题翻译：预干燥的药物输送用于使用STENT
公开(公告)号：WO2006036983A3
公开(公告)日：2006-09-14
申请号：PCT/US2005034681
申请日：2005-09-28
申请人： ATRIUM MEDICAL CORP , LABRECQUE ROGER , MOODIE GEOFFREY , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , CONROY SUZANNE , SUNTER BRIAN , HENRICH GEORGETTE
发明人： LABRECQUE ROGER , MOODIE GEOFFREY , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , CONROY SUZANNE , SUNTER BRIAN , HENRICH GEORGETTE
IPC分类号： A61F2/02 , A61F2/82 , A61F2/86
CPC分类号： A61L31/08 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61K47/10 , A61K47/22 , A61K47/44 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/22 , A61L2300/416 , A61L2300/428 , A61L2300/45 , A61L2300/606 , A61L2300/802 , A61L2420/02 , A61M25/0009 , A61M25/0045
摘要： A method and apparatus for the provision of a coating for application to a medical device results in a medical device having a bio-absorbable coating. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component and solvent can also be provided. The solvent is removed from the coating before the coating is applied to the medical device. The coated medical device is implantable in a patient to effect controlled delivery of the coating, including the therapeutic agent, to the patient.
摘要翻译：提供用于医疗装置的涂层的方法和装置导致具有生物可吸收涂层的医疗装置。涂层包括生物吸收载体组分。除了生物吸收性载体成分之外，还可以提供治疗剂成分和溶剂。在将涂层施加到医疗装置之前，从涂层中除去溶剂。涂覆的医疗装置可植入患者体内以实现对包括治疗剂在内的涂层的可控输送。

3. 发明申请

WO2006036970A2 METHOD OF THICKENING A COATING USING A DRUG 审中-公开
标题翻译：使用药物增稠涂层的方法
公开(公告)号：WO2006036970A2
公开(公告)日：2006-04-06
申请号：PCT/US2005034615
申请日：2005-09-28
申请人： ATRIUM MEDICAL CORP , LABRECQUE ROGER , MOODIE GEOFFREY , CONROY SUZANNE , ROGERS LISA , FERRARO JOSEPH , KARWOSKI THEODORE , HERWECK STEVE A , MARTAKOS PAUL
发明人： LABRECQUE ROGER , MOODIE GEOFFREY , CONROY SUZANNE , ROGERS LISA , FERRARO JOSEPH , KARWOSKI THEODORE , HERWECK STEVE A , MARTAKOS PAUL
IPC分类号： A61K35/60 , A61F2/00
CPC分类号： A61L31/08 , A61F2/07 , A61F2/885 , A61F2/90 , A61F2002/065 , A61F2002/075 , A61L31/10 , A61L31/16 , A61L2300/606 , A61L2300/802
摘要： A method for the provision of a coating on an implantable medical device results in a medical device having a bio-absorbable coating. The coating includes a bioabsorbable carrier component. In addition to the bio-absorbable carrier component, a dissolved therapeutic agent component can also be provided. The coated medical device is implantable in a patient to effect controlled delivery of the coating, including the dissolved therapeutic agent, to the patient.
摘要翻译：用于在可植入医疗装置上提供涂层的方法导致具有生物可吸收涂层的医疗装置。该涂层包含生物可吸收载体组分。除了生物可吸收载体成分之外，还可以提供溶解的治疗剂成分。涂覆的医疗装置可植入患者体内以实现涂层（包括溶解的治疗剂）向患者的受控递送。

4. 发明申请

WO2008039308A2 PERFORATED BIOABSORBABLE OIL FILM AND METHODS FOR MAKING THE SAME 审中-公开
标题翻译：有效的生物可溶性油膜及其制备方法
公开(公告)号：WO2008039308A2
公开(公告)日：2008-04-03
申请号：PCT/US2007019978
申请日：2007-09-14
申请人： ATRIUM MEDICAL CORP , HERWECK STEVE A , SWANICK THOMAS M , FERRARO JOSEPH , MARTAKOS PAUL , ROGERS LISA , KARWOSKI THEODORE , FAUCHER KEITH M , MCNAMARA PHILIP , LABRECQUE ROGER , CONROY SUZANNE , CARLTON TREVOR
发明人： HERWECK STEVE A , SWANICK THOMAS M , FERRARO JOSEPH , MARTAKOS PAUL , ROGERS LISA , KARWOSKI THEODORE , FAUCHER KEITH M , MCNAMARA PHILIP , LABRECQUE ROGER , CONROY SUZANNE , CARLTON TREVOR
IPC分类号： A61L31/00 , A61L31/14
CPC分类号： B65B55/18 , A61B2017/00004 , A61B2017/320044 , A61B2090/0816 , A61F2/0059 , A61L2/07 , A61L2/081 , A61L2/087 , A61L2/14 , A61L2/186 , A61L2/206 , A61L2/208 , A61L31/00 , A61L31/145 , A61L31/148 , A61L2202/24 , B26F1/18 , B29C39/02 , B65B31/04 , Y10T83/0481
摘要： A bio-absorbable stand-alone film is derived at least in part from fatty acids. The bio-absorbable stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents incorporated therein. The stand-alone film has one or more perforations or depressions formed therein. Corresponding methods of making the bio- absorbable stand-alone film with one or more perforations or depressions include molding, cutting, carving, puncturing or otherwise suitable methods to create the perforations or depressions in the bio-absorbable stand-alone film. The resulting stand alone film is bio-absorbable.
摘要翻译：生物可吸收的独立膜至少部分地由脂肪酸衍生。生物吸收性独立膜可以具有抗粘连性，抗炎性，非炎性和伤口愈合性，并且还可以包括一种或多种掺入其中的治疗剂。独立膜具有形成在其中的一个或多个穿孔或凹陷。使具有一个或多个穿孔或凹陷的生物吸收性独立膜的相应方法包括成型，切割，雕刻，穿刺或其它合适的方法以在生物吸收性独立膜中产生穿孔或凹陷。所得的独立薄膜是可吸收的。

5. 发明申请

WO2006037080A2 UV CURED GEL AND METHOD OF MAKING 审中-公开
标题翻译： UV固化凝胶及其制备方法
公开(公告)号：WO2006037080A2
公开(公告)日：2006-04-06
申请号：PCT/US2005034941
申请日：2005-09-28
申请人： ATRIUM MEDICAL CORP , LABRECQUE ROGER , MACNAMARA PHILIP , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , FAUCHER KEITH
发明人： LABRECQUE ROGER , MACNAMARA PHILIP , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , FAUCHER KEITH
IPC分类号： A61L33/00 , A61F2/00 , A61K9/14 , B05D3/00
CPC分类号： A61K35/60 , A61F2/06 , A61F13/02 , A61F13/023 , A61F2250/0067 , A61K9/0024 , A61K9/06 , A61K31/225 , A61K31/355 , A61K38/13 , A61K47/12 , A61K47/14 , A61L2/07 , A61L2/081 , A61L2/087 , A61L2/206 , A61L2/208 , A61L27/36 , A61L27/3604 , A61L27/52 , A61L27/54 , A61L31/005 , A61L31/10 , A61L31/145 , A61L2202/24 , A61L2300/22 , A61L2300/252 , A61L2300/404 , A61L2300/41 , A61L2300/414 , A61L2300/42 , A61L2300/602 , B05D3/067
摘要： A method of UV curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The cross-linked gel is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel derived from at least one fatty acid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent. The curing method can vary the application of UV light in both intensity and duration to achieve a desired amount of cross-linking forming the gel.
摘要翻译：提供UV固化方法和相应的所得非聚合物交联凝胶。交联凝胶可以与医疗装置结构组合。除了改善的愈合和抗炎反应之外，交联凝胶还可以提供抗粘连特性。交联凝胶通常由天然存在的油或部分天然存在的油形成的油组合物形成，所述油组合物至少部分固化形成衍生自至少一种脂肪酸化合物的交联凝胶。另外，油组合物可以包含治疗剂组分，例如药物或其他生物活性剂。固化方法可以在强度和持续时间两方面改变UV光的应用，以实现形成凝胶的期望量的交联。

6. 发明申请

WO2006037080A8 UV CURED GEL AND METHOD OF MAKING 审中-公开
公开(公告)号：WO2006037080A8
公开(公告)日：2006-09-14
申请号：PCT/US2005034941
申请日：2005-09-28
申请人： ATRIUM MEDICAL CORP , LABRECQUE ROGER , MACNAMARA PHILIP , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , FAUCHER KEITH
发明人： LABRECQUE ROGER , MACNAMARA PHILIP , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE A , FAUCHER KEITH
IPC分类号： A61F2/02
CPC分类号： A61K35/60 , A61F2/06 , A61F13/02 , A61F13/023 , A61F2250/0067 , A61K9/0024 , A61K9/06 , A61K31/225 , A61K31/355 , A61K38/13 , A61K47/12 , A61K47/14 , A61L2/07 , A61L2/081 , A61L2/087 , A61L2/206 , A61L2/208 , A61L27/36 , A61L27/3604 , A61L27/52 , A61L27/54 , A61L31/005 , A61L31/10 , A61L31/145 , A61L2202/24 , A61L2300/22 , A61L2300/252 , A61L2300/404 , A61L2300/41 , A61L2300/414 , A61L2300/42 , A61L2300/602 , B05D3/067
摘要： A method of UV curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The cross-linked gel is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel derived from at least one fatty acid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent. The curing method can vary the application of UV light in both intensity and duration to achieve a desired amount of cross-linking forming the gel.

7. 发明申请

WO2005027996A3 APPLICATION OF A THERAPEUTIC SUBSTANCE TO A TISSUE LOCATION USING AN EXPANDABLE MEDICAL DEVICE 审中-公开
标题翻译：使用可扩展的医疗设备将组合物置于组织位置
公开(公告)号：WO2005027996A3
公开(公告)日：2006-06-08
申请号：PCT/US2004030541
申请日：2004-09-15
申请人： ATRIUM MEDICAL CORP , HERWECK STEVE A , MARTAKOS PAUL , MOODIE GEOFFREY , LABRECQUE ROGER , KARWOSKI THEODORE , CARLTON TREVOR
发明人： HERWECK STEVE A , MARTAKOS PAUL , MOODIE GEOFFREY , LABRECQUE ROGER , KARWOSKI THEODORE , CARLTON TREVOR
IPC分类号： A61M25/00 , A61K9/22 , A61K31/225 , A61L29/16 , A61L31/16 , A61M20060101 , A61M25/16
CPC分类号： A61L29/16 , A61L31/16 , A61L2300/606
摘要： A non-polymeric or biological coating applied to radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.
摘要翻译：应用于可径向扩张的介入医疗装置的非聚合物或生物涂层提供了涂层和与其混合的任何治疗剂的均匀药物分布和渗透到体内的目标治疗区域。涂层是无菌的，并且能够在径向膨胀后由无菌医疗装置携带到身体内的目标组织位置。治疗性涂层部分地由于与组织的生物吸引而部分地转移到医疗装置上，并且部分地从医疗装置到与医疗装置接触的目标组织位置的物理转移。因此，在用非炎性涂层放置在患者体内之后，实现无创的局部组织转移递送以使均匀的治疗剂分布和受控的生物吸收进入组织。

8. 发明申请

WO2005027994A3 APPLICATION OF A THERAPEUTIC SUBSTANCE TO A TISSUE LOCATION USING A POROUS MEDICAL DEVICE 审中-公开
标题翻译：使用多种医疗设备将组合物的应用于组织位置
公开(公告)号：WO2005027994A3
公开(公告)日：2006-05-04
申请号：PCT/US2004030173
申请日：2004-09-15
申请人： ATRIUM MEDICAL CORP , HERWECK STEVE A , MARTAKOS PAUL , MOODIE GEOFFREY , LABRECQUE ROGER , KARWOSKI THEODORE , CARLTON TREVOR
发明人： HERWECK STEVE A , MARTAKOS PAUL , MOODIE GEOFFREY , LABRECQUE ROGER , KARWOSKI THEODORE , CARLTON TREVOR
IPC分类号： A61B5/05 , A61F2/82 , A61M20060101 , A61M5/32
CPC分类号： A61M25/10 , A61F2/82 , A61F2/958 , A61F2250/0067 , A61M25/1027 , A61M25/104 , A61M2025/105 , A61M2025/1088
摘要： A non-polymeric or biological coating applied to porous radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.
摘要翻译：应用于多孔径向可扩张介入医疗装置的非聚合物或生物涂层提供了涂层和与其混合的任何治疗剂的均匀药物分布和渗透到体内的目标治疗区域。涂层是无菌的，并且能够在径向膨胀后由无菌医疗装置携带到身体内的目标组织位置。治疗涂层部分地由于与组织的生物吸引而部分地转移离开医疗装置，并且部分地从医疗装置到与医疗装置接触的目标组织位置的物理转移。因此，在用非炎性涂层放置在患者体内之后，实现了不均匀的局部组织转移递送，用于均匀的治疗剂分布和对组织的受控生物吸收。

9. 发明申请

WO2007011385A2 HEAT CURED GEL AND METHOD OF MAKING 审中-公开
标题翻译：热固化凝胶和制备方法
公开(公告)号：WO2007011385A2
公开(公告)日：2007-01-25
申请号：PCT/US2005034678
申请日：2005-09-28
申请人： ATRIUM MEDICAL CORP , LABRECQUE ROGER , MCNAMARA PHILIP , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE , FAUCHER KEITH
发明人： LABRECQUE ROGER , MCNAMARA PHILIP , FERRARO JOSEPH , ROGERS LISA , MARTAKOS PAUL , KARWOSKI THEODORE , HERWECK STEVE , FAUCHER KEITH
IPC分类号： A61L33/00 , A61F2/00 , A61K9/14 , B05D3/00
CPC分类号： A61K35/60 , A61F2/06 , A61F13/02 , A61F13/023 , A61F2250/0067 , A61K9/0024 , A61K9/06 , A61K31/225 , A61K31/355 , A61K38/13 , A61K47/12 , A61K47/14 , A61L2/07 , A61L2/081 , A61L2/087 , A61L2/206 , A61L2/208 , A61L27/36 , A61L27/3604 , A61L27/52 , A61L27/54 , A61L31/005 , A61L31/10 , A61L31/145 , A61L2202/24 , A61L2300/22 , A61L2300/252 , A61L2300/404 , A61L2300/41 , A61L2300/414 , A61L2300/42 , A61L2300/602 , B05D3/067
摘要： A method of curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The cross-linked gel is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel derived from at least one fattyacid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent. The curing method can vary the application of heat in both temperature and duration to achieve a desired amount of cross-linking forming the gel.
摘要翻译：提供固化方法和相应的所得非聚合交联凝胶。交联凝胶可以与医疗装置结构组合。除了改善愈合和抗炎反应之外，交联凝胶还可提供抗粘附特性。交联凝胶通常由天然存在的油或部分天然存在的油形成的油组合物形成，其至少部分固化形成由至少一种脂肪酸化合物衍生的交联凝胶。此外，油组合物可以包括治疗剂组分，例如药物或其它生物活性剂。固化方法可以在温度和持续时间内改变热量的应用以实现形成凝胶的所需量的交联。

10. 发明申请

WO2004105832A3 KINETIC ISOLATION PRESSURIZATION 审中-公开
标题翻译：动力隔离加压
公开(公告)号：WO2004105832A3
公开(公告)日：2005-08-18
申请号：PCT/US2004015992
申请日：2004-05-21
申请人： ATRIUM MEDICAL CORP , HERWECK STEVE A , MARTAKOS PAUL , MOODIE GEOFFREY , LABRECQUE ROGER
发明人： HERWECK STEVE A , MARTAKOS PAUL , MOODIE GEOFFREY , LABRECQUE ROGER
IPC分类号： A61M20060101 , A61M25/00 , A61M25/10 , A61M29/00 , A61M31/00
CPC分类号： A61M25/10 , A61M2025/0057 , A61M2025/105
摘要： A method of delivering a therapeutic agent to a targeted location within a patient efficiently delivers the agent with a reduced systemic effect. The method includes providing a non-perforated delivery device (10) having at least one wall (12) through which a fluid at first fluid pressure can pass through. The non-perforated delivery device (10) is positioned to provide a radial fluid force against the targeted location. The fluid, including at least one therapeutic agent, is supplied to the therapeutic agent delivery device (10) at the first fluid pressure. The fluid passes through the at least one wall (12) of the delivery device (10) to create a semi-confined space external to the delivery device (10) at a second fluid pressure. The delivery device (10) applies the radial fluid force against the semi-confined space and the fluid disposed therein while simultaneously facilitating the fluid passing through the delivery device (10) to maintain the second fluid pressure in the semi-confined space at the targeted location. The fluid contains at least one therapeutic agent that is distributed to the targeted location in a substantially uniform distribution in an amount sufficient to create a therapeutic effect modulatable by the fluid pressure and a dwell time.
摘要翻译：将治疗剂递送到患者中的目标位置的方法有效地递送具有降低的系统效应的药剂。该方法包括提供具有至少一个壁（12）的非穿孔输送装置（10），第一流体压力下的流体可通过该壁穿过。非穿孔输送装置（10）被定位成提供抵抗目标位置的径向流体力。包括至少一种治疗剂的流体在第一流体压力下被供应到治疗剂递送装置（10）。流体通过输送装置（10）的至少一个壁（12），以在第二流体压力下产生输送装置（10）外部的半限制空间。输送装置（10）对半封闭空间和设置在其中的流体施加径向流体力，同时促使流体通过输送装置（10），以将半封闭空间中的第二流体压力保持在目标位置。流体包含至少一种治疗剂，其以足以产生可通过流体压力和停留时间调节的治疗效果的量以基本均匀的分布分布到目标位置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式