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1. 发明授权

US09883936B2 Atrial appendage blood filtration systems 有权
公开(公告)号：US09883936B2
公开(公告)日：2018-02-06
申请号：US14806446
申请日：2015-07-22
申请人： ATRITECH, INC.
发明人： Gregg S. Sutton , Jeffrey Welch , Dean A. Peterson , John B. Bridgeman , Bruce R. Youngberg
IPC分类号： A61M29/00 , A61F2/01 , A61B17/00 , A61B17/12
CPC分类号： A61F2/01 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/12095 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/008 , A61F2230/0093
摘要： Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. A compressed filter device attached to a tether wire is loaded in the delivery tube. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. A filter membrane in the deployed device extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium.

2. 发明授权

US10751158B2 Atrial appendage blood filtration systems 有权
公开(公告)号：US10751158B2
公开(公告)日：2020-08-25
申请号：US15864412
申请日：2018-01-08
申请人： ATRITECH, INC.
发明人： Gregg S. Sutton , Jeffrey Welch , Dean A. Peterson , John B. Bridgeman , Bruce R. Youngberg
IPC分类号： A61F2/01 , A61B17/00 , A61B17/12
摘要： Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. A compressed filter device attached to a tether wire is loaded in the delivery tube. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. A filter membrane in the deployed device extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium.

3. 发明授权

US10278805B2 Expandable implant devices for filtering blood flow from atrial appendages 有权
公开(公告)号：US10278805B2
公开(公告)日：2019-05-07
申请号：US14866017
申请日：2015-09-25
申请人： ATRITECH, INC.
发明人： Thomas E. Borillo , Dean Peterson , Gregg S. Sutton , Jeffrey Welch
IPC分类号： A61F2/06 , A61F2/01 , A61B17/12 , A61B17/00
摘要： Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

4. 发明申请

US20160008122A1 EXPANDABLE IMPLANT DEVICES FOR FILTERING BLOOD FLOW FROM ATRIAL APPENDAGES 审中-公开
标题翻译：用于从ATRIAL附件过滤血液的可扩展植入装置
公开(公告)号：US20160008122A1
公开(公告)日：2016-01-14
申请号：US14866017
申请日：2015-09-25
申请人： ATRITECH, INC.
发明人： Thomas E. Borillo , Dean Peterson , Gregg S. Sutton , Jeffrey Welch
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12122 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B2017/00575 , A61F2/01 , A61F2002/015 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/008
摘要： Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.
摘要翻译：用于过滤血流通过心房的口的植入装置具有其中一个或多个可膨胀的部件结构。具有未膨胀状态的组件结构的装置具有适合于皮内递送至心房附属部位的紧凑尺寸。可扩展组件结构在现场扩展以部署设备。装置可以具有足够短的轴向长度，使得装置长度的大部分或几乎全部可以适合于口腔区域。

5. 发明申请

US20160051358A1 ATRIAL APPENDAGE BLOOD FILTRATION SYSTEMS 审中-公开
标题翻译： ATRIAL附录血液过滤系统
公开(公告)号：US20160051358A1
公开(公告)日：2016-02-25
申请号：US14806446
申请日：2015-07-22
申请人： ATRITECH, INC.
发明人： Gregg S. Sutton , Jeffrey Welch , Dean A. Peterson , John B. Bridgeman , Bruce R. Youngberg
IPC分类号： A61F2/01 , A61B17/12 , A61B17/00
CPC分类号： A61F2/01 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/12095 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/008 , A61F2230/0093
摘要： Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. The curved access sheath is coursed through the patient's vasculature to gain transseptal access to a left atrial appendage. A compressed filter device attached to a tether wire is loaded in the delivery tube. The loaded delivery tube is advanced through the pre-positioned access sheath to place the device in a deployment position. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. The expelled device, which is not constrained by the delivery tube walls, self expands to its useful size in the subject atrial appendage. A filter membrane in the deployed extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium.
摘要翻译：用于将血液过滤装置经皮递送至心房附件的仪器包括弯曲通道护套和输送管。弯曲的通路护套通过患者的脉管系统通过，以获得左心耳通过的通路。附接到系绳的压缩过滤器装置装载在输送管中。装载的输送管通过预定位的进入护套前进，以将装置置于展开位置。进入护套和输送管可以机械地锁定并一起移动，以将装置放置在合适的展开位置。通过将输送管缩回到系绳上，或者通过将系绳向前移动通过输送管，将装置从输送管排出。不受输送管壁约束的排出的装置在主题心耳中自我膨胀到其有用的尺寸。所部署的过滤膜延伸穿过附属口，以过滤通过口的血液流。滤膜被配置成呈现出通过口的心房血流的平坦表面。

6. 发明申请

US20140107696A1 EXPANDABLE IMPLANT DEVICES FOR FILTERING BLOOD FLOW FROM ATRIAL APPENDAGES 审中-公开
标题翻译：用于从ATRIAL附件过滤血液的可扩展植入装置
公开(公告)号：US20140107696A1
公开(公告)日：2014-04-17
申请号：US14147149
申请日：2014-01-03
申请人： Atritech, Inc.
发明人： Thomas E. Borillo , Dean Peterson , Gregg S. Sutton , Jeffrey Welch
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12122 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B2017/00575 , A61F2/01 , A61F2002/015 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/008
摘要： Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.
摘要翻译：用于过滤血流通过心房的口的植入装置具有其中一个或多个可膨胀的部件结构。具有未膨胀状态的组件结构的装置具有适合于皮内递送至心房附属部位的紧凑尺寸。可扩展组件结构在现场扩展以部署设备。装置可以具有足够短的轴向长度，使得装置长度的大部分或几乎全部可以适合于口腔区域。

7. 发明申请

US20180140412A1 ATRIAL APPENDAGE BLOOD FILTRATION SYSTEMS 审中-公开
公开(公告)号：US20180140412A1
公开(公告)日：2018-05-24
申请号：US15864412
申请日：2018-01-08
申请人： ATRITECH, INC.
发明人： Gregg S. Sutton , Jeffrey Welch , Dean A. Peterson , John B. Bridgeman , Bruce R. Youngberg
IPC分类号： A61F2/01 , A61B17/00 , A61B17/12
摘要： Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. A compressed filter device attached to a tether wire is loaded in the delivery tube. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. A filter membrane in the deployed device extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium.

8. 发明申请

US20160058539A1 FILTER APPARATUS FOR OSTIUM OF LEFT ATRIAL APPENDAGE 审中-公开
标题翻译：过滤装置用于左心室附件
公开(公告)号：US20160058539A1
公开(公告)日：2016-03-03
申请号：US14845524
申请日：2015-09-04
申请人： ATRITECH INC.
发明人： Robert A. VanTassel , Robert G. Hauser , Robert Schwartz , David Holmes , Gregg S. Sutton , Thomas E. Borillo , Jeffrey Welch
IPC分类号： A61F2/01 , A61B17/12 , A61B17/00
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/12122 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B2017/00243 , A61B2017/00597 , A61B2017/00619 , A61B2017/00632 , A61B2017/1205 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/0069 , A61F2230/0076 , A61F2230/0078 , A61F2230/008 , A61F2230/0093
摘要： Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage.The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g., an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.
摘要翻译：用于永久性放置在患者左心耳的口上的装置，其包括配置成延伸穿过左心耳的口的过滤膜。过滤膜具有允许血液流过但可以基本上抑制血栓通过的可渗透结构。该装置还包括附接到过滤膜的支撑结构，其通过永久地接合左心耳内壁的一部分而将过滤膜保持在左心耳的口处的适当位置。支撑结构可以从第一构型径向扩张到接合左心耳的口或内壁的第二构型。过滤膜可以限定穿过其中的开口，其被构造成从阻止血栓通过的第一尺寸膨胀到允许介入装置（例如膨胀气囊）穿过其中的第二尺寸，并且其中开口是弹性的偏向于第一大小。

9. 发明授权

US09132000B2 Filter apparatus for ostium of left atrial appendage 有权
标题翻译：左心耳口滤器
公开(公告)号：US09132000B2
公开(公告)日：2015-09-15
申请号：US13922024
申请日：2013-06-19
申请人： ATRITECH INC.
发明人： Robert A. VanTassel , Robert G. Hauser , Robert Schwartz , David Holmes , Gregg S. Sutton , Thomas E. Borillo , Jeffrey Welch
IPC分类号： A61M29/00 , A61F2/01 , A61B17/12 , A61B17/00
CPC分类号： A61F2/01 , A61B17/00234 , A61B17/0057 , A61B17/12122 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B2017/00243 , A61B2017/00597 , A61B2017/00619 , A61B2017/00632 , A61B2017/1205 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/0069 , A61F2230/0076 , A61F2230/0078 , A61F2230/008 , A61F2230/0093
摘要： Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g., an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.
摘要翻译：用于永久性放置在患者左心耳的口上的装置，其包括配置成延伸穿过左心耳的口的过滤膜。过滤膜具有允许血液流过但可以基本上抑制血栓通过的可渗透结构。该装置还包括附接到过滤膜的支撑结构，其通过永久地接合左心耳内壁的一部分而将过滤膜保持在左心耳的口处的适当位置。支撑结构可以从第一构型径向扩张到接合左心耳的口或内壁的第二构型。过滤膜可以限定穿过其中的开口，其被构造成从阻止血栓通过的第一尺寸膨胀到允许介入装置例如膨胀气囊通过的第二尺寸，并且其中开口是弹性的偏向于第一大小。

10. 发明申请

US20140163605A1 FILTER APPARATUS FOR OSTIUM OF LEFT ATRIAL APPENDAGE 审中-公开
标题翻译：过滤装置用于左心室附件
公开(公告)号：US20140163605A1
公开(公告)日：2014-06-12
申请号：US13922024
申请日：2013-06-19
申请人： ATRITECH INC.
发明人： Robert A. VanTassel , Robert G. Hauser , Robert Schwartz , David Holmes , Gregg S. Sutton , Thomas E. Borillo , Jeffrey Welch
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61B17/00234 , A61B17/0057 , A61B17/12122 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B2017/00243 , A61B2017/00597 , A61B2017/00619 , A61B2017/00632 , A61B2017/1205 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/0069 , A61F2230/0076 , A61F2230/0078 , A61F2230/008 , A61F2230/0093
摘要： Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g., an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.
摘要翻译：用于永久性放置在患者左心耳的口上的装置，其包括配置成延伸穿过左心耳的口的过滤膜。过滤膜具有允许血液流过但可以基本上抑制血栓通过的可渗透结构。该装置还包括附接到过滤膜的支撑结构，其通过永久地接合左心耳内壁的一部分而将过滤膜保持在左心耳的口处的适当位置。支撑结构可以从第一构型径向扩张到接合左心耳的口或内壁的第二构型。过滤膜可以限定穿过其中的开口，其被构造成从阻止血栓通过的第一尺寸膨胀到允许介入装置例如膨胀气囊通过的第二尺寸，并且其中开口是弹性的偏向于第一大小。

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