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1. 发明申请

WO2014036238A1 AXMI-234 AND AXMI-235 TOXIN GENES AND METHODS FOR THEIR USE 审中-公开
标题翻译： AXMI-234和AXMI-235毒素基因及其使用方法
公开(公告)号：WO2014036238A1
公开(公告)日：2014-03-06
申请号：PCT/US2013/057258
申请日：2013-08-29
申请人： ATHENIX CORP.
发明人： SAMPSON, Kimberly, S.
IPC分类号： C12N15/82 , C07K14/325
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/00 , C07K14/325 , C12N15/8285 , Y02A40/162 , Y02A40/164
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:3-6, or the nucleotide sequence set forth in SEQ ID NO:1 or 2, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：3-6所示的氨基酸序列的核苷酸序列或SEQ ID NO：1或2所示的核苷酸序列，以及变体和片段。

2. 发明申请

WO2013134523A1 BACILLUS THURINGIENSIS TOXIN GENE AXMI335 AND METHODS FOR ITS USE 审中-公开
标题翻译： BACILLUS THURINGIENSIS TOXIN基因AXMI335及其使用方法
公开(公告)号：WO2013134523A1
公开(公告)日：2013-09-12
申请号：PCT/US2013/029647
申请日：2013-03-07
申请人： ATHENIX CORP.
发明人： SAMPSON, Kimberly, S. , THAYER, Rebecca , LEHTINEN, Duane
IPC分类号： C07K14/32 , C12N15/82
CPC分类号： C07K14/325 , A01N37/18 , C12N15/8285 , C12N15/8286 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2 or 4, or the nucleotide sequence set forth in SEQ ID NO: 1 or 3, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：2或4所示的氨基酸序列的核苷酸序列或SEQ ID NO：1或3所示的核苷酸序列，以及变体和片段。

3. 发明申请

WO2013019600A1 AXMI279 PESTICIDAL GENE AND METHODS FOR ITS USE 审中-公开
标题翻译： AXMI279农药基因及其使用方法
公开(公告)号：WO2013019600A1
公开(公告)日：2013-02-07
申请号：PCT/US2012/048488
申请日：2012-07-27
申请人： ATHENIX CORP. , SAMPSON, Kimberly, S. , BALASUBRAMANIAN, Deepa , LEHTINEN, Duane, A.
发明人： SAMPSON, Kimberly, S. , BALASUBRAMANIAN, Deepa , LEHTINEN, Duane, A.
IPC分类号： C12N15/82 , C07K14/325 , A01H5/00
CPC分类号： C12N15/8286 , A01H5/10 , A01H5/12 , C07K14/195 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 3, or 4, the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含杀虫多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的杀虫核酸分子。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了包含编码SEQ ID NO：2,3或4所示氨基酸序列，SEQ ID NO：1所示核苷酸序列以及变体和片段的核苷酸序列的核酸分子它们。

4. 发明申请

WO2015038262A2 AXMI281 TOXIN GENE AND METHODS FOR ITS USE 审中-公开
标题翻译： AXMI281毒素基因及其使用方法
公开(公告)号：WO2015038262A2
公开(公告)日：2015-03-19
申请号：PCT/US2014/050316
申请日：2014-08-08
申请人： ATHENIX CORP.
发明人： THAYER, Rebecca , SAMPSON, Kimberly, S. , LEHTINEN, Duane , PETERS, Cheryl
IPC分类号： C07K14/325
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2-5, or the nucleotide sequence set forth in SEQ ID NO: 1, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物和细菌中转化和表达。组合物还包含转化的细菌，植物，植物细胞，组织和种子。具体而言，提供了分离的毒素核酸分子。此外，还包括对应于多核苷酸的氨基酸序列，以及与那些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：2-5所示的氨基酸序列或SEQ ID NO：1所示的核苷酸序列的核苷酸序列，以及其变体和片段

5. 发明申请

WO2012135501A2 AXMI232, AXMI233, AND AXMI249 TOXIN GENES AND METHODS FOR THEIR USE 审中-公开
标题翻译： AXMI232，AXMI233和AXMI249毒素基因及其使用方法
公开(公告)号：WO2012135501A2
公开(公告)日：2012-10-04
申请号：PCT/US2012/031214
申请日：2012-03-29
申请人： ATHENIX CORP. , SAMPSON, Kimberly, S.
发明人： SAMPSON, Kimberly, S.
IPC分类号： C12N15/82 , C07K14/325
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/325 , C12N15/8261 , Y02A40/146 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:4-19, or the nucleotide sequence set forth in SEQ ID NO: 1-3, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物和细菌中转化和表达。组合物还包含转化的细菌，植物，植物细胞，组织和种子。具体而言，提供了分离的毒素核酸分子。此外，还包括对应于多核苷酸的氨基酸序列，以及与那些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：4-19所示氨基酸序列或SEQ ID NO：1-3所示核苷酸序列的核苷酸序列，以及变体和片段。

6. 发明申请

WO2015041769A2 AXMI440 TOXIN GENE AND METHODS FOR ITS USE 审中-公开
标题翻译： AXMI440毒素基因及其使用方法
公开(公告)号：WO2015041769A2
公开(公告)日：2015-03-26
申请号：PCT/US2014/050327
申请日：2014-08-08
申请人： ATHENIX CORP.
发明人： THAYER, Rebecca , SAMPSON, Kimberly, S. , LEHTINEN, Duane , MAGALHAES, Leonardo
IPC分类号： A01H5/00 , C12N15/82
CPC分类号： C12N15/8286 , C07K14/325
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:3-6, or the nucleotide sequence set forth in SEQ ID NO: 1 or 2, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：3-6所示的氨基酸序列的核苷酸序列或SEQ ID NO：1或2所示的核苷酸序列，以及变体和片段。

7. 发明申请

WO2015021367A2 AXMI422 TOXIN GENE AND METHODS FOR ITS USE 审中-公开
标题翻译： AXMI422毒素基因及其使用方法
公开(公告)号：WO2015021367A2
公开(公告)日：2015-02-12
申请号：PCT/US2014/050319
申请日：2014-08-08
申请人： ATHENIX CORP.
发明人： ROBERTS, Kira , SAMPSON, Kimberly, S. , LEHTINEN, Duane , MAGALHAES, Leanardo
IPC分类号： A01H5/00 , C12N15/82
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2-3, or the nucleotide sequence set forth in SEQ ID NO: l, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中用于在植物和细菌中转化和表达。组合物还包含转化的细菌，植物，植物细胞，组织和种子。具体而言，提供了分离的毒素核酸分子。此外，还包括对应于多核苷酸的氨基酸序列，以及与那些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：2-3所示的氨基酸序列或SEQ ID NO：1所示的核苷酸序列的核苷酸序列，以及其变体和片段

8. 发明申请

WO2011103248A2 AXMI221z, AXMI222z, AXMI223z, AXMI224z, AND AXMI225z DELTA-ENDOTOXIN GENES AND METHODS FOR THEIR USE 审中-公开
标题翻译： AXMI221z，AXMI222z，AXMI223z，AXMI224z和AXMI225Z DELTA-ENDOTOXIN基因及其使用方法
公开(公告)号：WO2011103248A2
公开(公告)日：2011-08-25
申请号：PCT/US2011/025172
申请日：2011-02-17
申请人： ATHENIX CORP. , SAMPSON, Kimberly, S. , TOMSO, Daniel, John
发明人： SAMPSON, Kimberly, S. , TOMSO, Daniel, John
IPC分类号： A01H5/00 , C07H21/04 , C12N15/63 , C12N1/21 , C12N5/10 , C07K14/00 , A01N37/18 , C12P21/00 , A01H1/00 , C12N15/82 , A01H5/10 , A01P7/04
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/02 , C07K14/325 , C07K16/1278 , C12N15/8279 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO :21-32, or the nucleotide sequence set forth in SEQ ID NO: 1-20, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了分离的核酸分子，其包含编码SEQ ID NO：21-32所示的氨基酸序列的核苷酸序列或SEQ ID NO：1-20所示的核苷酸序列，以及变体和片段。

9. 发明申请

WO2011002992A1 AXMI-205 PESTICIDAL GENE AND METHODS FOR ITS USE 审中-公开
标题翻译： AXMI-205农药基因及其使用方法
公开(公告)号：WO2011002992A1
公开(公告)日：2011-01-06
申请号：PCT/US2010/040778
申请日：2010-07-01
申请人： ATHENIX CORP. , DESAI, Nalini , HINSON, Jill , BALUSUBRAMANIAN, Deepa , SAMPSON, Kimberly, S. , TOMSO, Daniel, J. , LEHTINEN, Duane, Alan , DUCK, Nicholas, B.
发明人： DESAI, Nalini , HINSON, Jill , BALUSUBRAMANIAN, Deepa , SAMPSON, Kimberly, S. , TOMSO, Daniel, J. , LEHTINEN, Duane, Alan , DUCK, Nicholas, B.
IPC分类号： C12N15/82
CPC分类号： C07K14/195 , C07K14/22 , C07K16/1203 , C12N15/8285 , C12N15/8286 , C12Q1/6876 , Y02A40/162 , Y02A40/164
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 3, or 4, the nucleotide sequence set forth in SEQ ID NO: 1, 9, 10, or 11, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含杀虫多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的杀虫核酸分子。另外，包括对应于多核苷酸的氨基酸序列。特别地，本发明提供了包含编码SEQ ID NO：2,3或4所示氨基酸序列的核苷酸序列的核酸分子，SEQ ID NO：1,9,10或11所示的核苷酸序列，以及其变体和片段。

10. 发明申请

WO2015088937A8 AXMI477, AXMI482, AXMI486 AND AXMI525 TOXIN GENES FROM BACILLUS THURINGIENSIS AND METHODS FOR THEIR USE 审中-公开
公开(公告)号：WO2015088937A8
公开(公告)日：2015-06-18
申请号：PCT/US2014/068989
申请日：2014-12-08
申请人： ATHENIX CORP.
发明人： LEHTINEN, Duane Alan , SAMPSON, Kimberly, S. , ROBERTS, Kira , DUNN, Ethan , CHOUGULE, Nana
IPC分类号： C12N15/82 , C07K14/325
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a Bacillus thuringiensis toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:5-26, or the nucleotide sequence set forth in SEQ ID NO: 1-4, as well as variants and fragments thereof.

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