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1. 发明申请

WO2010042034A1 A BREATH ACTIVATED INHALER 审中-公开
标题翻译：呼吸激活的吸入器
公开(公告)号：WO2010042034A1
公开(公告)日：2010-04-15
申请号：PCT/SE2009/051111
申请日：2009-10-07
申请人： ASTRAZENECA AB , BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James, Daniel , PENHALLURICK, Trevor, John , SMARTT, Nick
发明人： BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James, Daniel , PENHALLURICK, Trevor, John , SMARTT, Nick
IPC分类号： A61M15/00 , B65D83/06
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： The invention relates to an inhaler, comprising an outlet and a plurality of sealed compartments containing medicament. An opening mechanism is provided to open the compartment presently aligned with the outlet. An indexing mechanism sequentially aligns the compartments with the outlet. A latch is provided for latching the opening mechanism in an energized position. The latch cannot latch the opening mechanism before the indexing mechanism has aligned the next compartment with the outlet. The invention also relates to a method of priming an inhaler and a method of dispensing a medicament from an inhaler.
摘要翻译：本发明涉及一种吸入器，其包括出口和多个包含药物的密封隔室。提供打开机构以打开目前与出口对齐的隔间。分度机构顺序地将隔间与出口对准。提供了用于将开启机构锁定在通电位置的闩锁。在分度机构将下一个隔间与出口对准之前，闩锁不能锁定打开机构。本发明还涉及一种起动吸入器的方法和从吸入器分配药物的方法。

2. 发明申请

WO2010042036A1 INHALER WITH AUDIBLE INDICATOR MEANS 审中-公开
标题翻译：吸入可乐指示器
公开(公告)号：WO2010042036A1
公开(公告)日：2010-04-15
申请号：PCT/SE2009/051114
申请日：2009-10-07
申请人： ASTRAZENECA AB , BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James, Daniel
发明人： BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James, Daniel
IPC分类号： A61M15/00 , B65D83/06
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0075 , A61M15/0096 , A61M2202/064 , A61M2205/073 , A61M2205/581
摘要： The invention relates to an inhaler comprising an outlet through which doses of medicament may be dispensed. The inhaler also comprises a dispensing mechanism having a primed state, in which it is ready for dispensing a dose, and a fired state, in which it has dispensed a dose. In one aspect, the inhaler also comprises a disabler which, after the final dose has been dispensed, is activated to disable the dispensing mechanism from generating a sound which has been audible when the dispensing mechanism has moved from its primed state to its fired state. In a second aspect, the disabler prevents the dispensing mechanism from being in its primed state when an outlet cover is in an open position, whereby a not ready indication is presented to the user.
摘要翻译：本发明涉及一种吸入器，其包括可以分配剂量的药物的出口。吸入器还包括具有底漆状态的分注机构，其中其准备好分配剂量，并且其已经分配剂量的烧制状态。在一个方面，吸入器还包括消除器，其在最终剂量被分配之后被激活，以使得分配机构不能产生当分配机构已经从其引发状态移动到其被发射状态时已被听到的声音。在第二方面，当出口盖处于打开位置时，消除器防止分配机构处于其初始化状态，从而向用户呈现未就绪的指示。

3. 发明申请

WO2010042033A1 INHALATION DEVICE AND METHOD OF DISPENSING MEDICAMENT 审中-公开
标题翻译：吸入装置和药物分配方法
公开(公告)号：WO2010042033A1
公开(公告)日：2010-04-15
申请号：PCT/SE2009/051110
申请日：2009-10-07
申请人： ASTRAZENECA AB , BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James Daniel , LASTOW, Orest , SMARTT, Nick
发明人： BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James Daniel , LASTOW, Orest , SMARTT, Nick
IPC分类号： A61M15/00 , B65D83/04
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0093 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： The present invention relates to an inhaler, comprising a base having at least one air-tight, foil-sealed cavity containing medicament. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. The invention also relates to a method of dispensing a medicament from a sealed cavity inside an inhaler.
摘要翻译：吸入器技术领域本发明涉及一种吸入器，其包括具有至少一个包含药物的气密的箔密封空腔的底座。致动器可接合附接到箔的分离元件，致动器具有通电位置，在该位置中，致动器被朝向卸载位置偏置，以使分离元件和附着的箔片远离腔体移动。闩锁具有第一位置，其中致动器在所述通电位置中锁定，其中闩锁至少部分地布置在流动路径中，使得通过流动路径的吸入流动影响闩锁从第一位置移动到第二名本发明还涉及从吸入器内部的密封空腔分配药物的方法。

4. 发明申请

WO2010042035A1 INHALER WITH INDEXING LINKED TO MOVEMENT OF COVER 审中-公开
标题翻译：具有与盖子运动相关联的吸入器
公开(公告)号：WO2010042035A1
公开(公告)日：2010-04-15
申请号：PCT/SE2009/051112
申请日：2009-10-07
申请人： ASTRAZENECA AB , BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James Daniel , PENHALLURICK, Trevor John
发明人： BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , JOHN, James Daniel , PENHALLURICK, Trevor John
IPC分类号： A61M15/00 , B65D83/06
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0096 , A61M2202/064 , A61M2205/073
摘要： The invention relates to a medical dispenser, comprising an outlet and a plurality of sealed compartments containing medicament to be sequentially aligned with and dispensed through said outlet. Movement of an actuator sequentially causes mechanical energy to be built up and then released and converted into an indexing movement of the compartments. The invention also relates to an indexing method for a medical dispenser.
摘要翻译：本发明涉及一种医用分配器，其包括出口和多个密封隔室，其包含与所述出口顺序对齐并通过所述出口分配的药物。执行机构的移动顺序地使得机械能被建立，然后释放并转换成隔间的分度运动。本发明还涉及医用分配器的分度方法。

5. 发明申请

WO2009102273A1 INHALER COMPRISING A PLURALITY OF CONSECUTIVE SEALED CAVITIES CONTAINING MEDICAMENTS 审中-公开
标题翻译：吸收包含药物的大量相关密封性
公开(公告)号：WO2009102273A1
公开(公告)日：2009-08-20
申请号：PCT/SE2009/050140
申请日：2009-02-11
申请人： ASTRAZENECA AB , BAKEWELL, William , BRIANT, John , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , LASTOW, Orest , SMARTT, Nick
发明人： BAKEWELL, William , BRIANT, John , COOKE, Charles , GROOMBRIDGE, Chris , HARRISON, Nick , LASTOW, Orest , SMARTT, Nick
IPC分类号： A61M15/00 , B65D83/04
CPC分类号： A61M15/0045 , A61M15/0043 , A61M15/0048 , A61M15/0091 , A61M15/0096 , A61M2202/064
摘要： The invention relates to an inhaler, comprising a base having a plurality of consecutive sealed cavities containing medicament. A foil is attached to the base for sealing the medicament within the cavities, wherein the width of the foil is defined by a first edge and a second edge of the foil. A plurality of separating elements, one for each cavity, are attached to the foil for separating a foil portion from a respective cavity. Between each pair of neighbouring separating elements, the foil is provided with an indication of fracture at said first edge, wherein when a separating element is moved away from the base, the foil starts to tear at said indication of fracture and continues to tear between the moving separating element and its neighbouring separating element until the foil has torn to said second edge.
摘要翻译：本发明涉及一种吸入器，其包括具有包含药物的多个连续密封空腔的底座。箔片附接到基座上，以密封空腔内的药物，其中箔片的宽度由箔片的第一边缘和第二边缘限定。多个分离元件（每个空腔一个）附接到箔片上，用于将箔片部分与相应的空腔分离。在每对相邻的分离元件之间，箔片在所述第一边缘处被提供有断裂的指示，其中当分离元件移动离开基部时，箔片在所述断裂指示处开始撕裂，并且继续在第移动分离元件及其相邻的分离元件，直到箔片撕裂到所述第二边缘。

6. 发明申请

WO2012010877A2 NEW DEVICE 审中-公开
标题翻译：新设备
公开(公告)号：WO2012010877A2
公开(公告)日：2012-01-26
申请号：PCT/GB2011/051349
申请日：2011-07-19
申请人： ASTRAZENECA AB , ASTRAZENECA UK LIMITED , ARVIDSSON, Lars, Rune, Gustav , BAKEWELL, William , BRIANT, John, Philip , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Christopher , JOHN, James, Daniel , LASTOW, Orest , PENHALLURICK, Trevor, John , SMARTT, Nicholas , SVENSSON, Mårten , ULLBRAND, Björn
发明人： ARVIDSSON, Lars, Rune, Gustav , BAKEWELL, William , BRIANT, John, Philip , CAMPBELL, Patrick , COOKE, Charles , GROOMBRIDGE, Christopher , JOHN, James, Daniel , LASTOW, Orest , PENHALLURICK, Trevor, John , SMARTT, Nicholas , SVENSSON, Mårten , ULLBRAND, Björn
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0021 , A61M15/0043 , A61M15/0048 , A61M15/0075 , A61M15/0081 , A61M15/0091 , A61M15/08 , A61M2202/064
摘要： A dry powder inhaler comprises a disc-shaped assembly (14) having cavities (16) filled with medicament powder for inhalation. The assembly is rotatably mounted in a housing (6, 8) on which is mounted a rotatable external casing (11, 12). A mouthpiece (10) is movably mounted on the housing (6, 8) allowing it to be brought into and out of engagement with the edge of the disc (14) whereby the mouthpiece acts as a brake to prevent or permit rotational movement of the disc (14). The inhaler is opened by rotating the housing with respect to the casing (11, 12) to expose the mouthpiece (10). As the inhaler is opened and closed, cam followers (105) on the mouthpiece move along cam tracks (109) in the casing (11, 12), causing the mouthpiece to move against or away from the disc (14). A gap is defined between the disc and mouthpiece to allow a flow of bypass air to enter the mouthpiece.
摘要翻译：干粉吸入器包括具有填充有用于吸入的药物粉末的空腔（16）的盘形组件（14）。组件可旋转地安装在壳体（6,8）中，其上安装有可旋转的外壳（11,12）。吸嘴（10）可移动地安装在壳体（6,8）上，允许其与盘（14）的边缘进入和离开接合，由此接口作为制动器来防止或允许光盘（14）。通过相对于壳体（11,12）旋转壳体来打开吸入器以暴露接口（10）。当吸入器打开和关闭时，口部上的凸轮从动件（105）沿壳体（11,12）中的凸轮轨道（109）移动，使得接口件能够抵靠或远离盘片（14）移动。在盘和接口之间限定间隙，以允许旁路空气流进入接口。

7. 发明申请

WO2009093969A1 A MEDICAMENT-CONTAINING DISPENSER PROVIDED WITH A DISPLAY FOR PRESENTING INDICIA TO A USER 审中-公开
标题翻译：包含用于向用户呈现INDICIA的显示器的药物包含分配器
公开(公告)号：WO2009093969A1
公开(公告)日：2009-07-30
申请号：PCT/SE2009/050056
申请日：2009-01-21
申请人： ASTRAZENECA AB , BRADSHAW, Douglas , BURSTALL, Oliver , CAMPBELL, Patrick , COOKE, Charles , CRAMER, William
发明人： BRADSHAW, Douglas , BURSTALL, Oliver , CAMPBELL, Patrick , COOKE, Charles , CRAMER, William
IPC分类号： A61M15/00 , A61J7/00
CPC分类号： A61M15/0045 , A61M15/0026 , A61M15/0065 , A61M15/0075 , A61M15/008 , A61M15/009 , A61M2202/064 , A61M2205/502 , A61M2205/582 , A61M2205/583 , A61M2205/584
摘要： The invention relates to a medicament-containing dispenser, such as an inhaler. The dispenser comprises an outlet for dispensing medicament, e.g. a mouthpiece or a nasal adaptor. The dispenser also comprises a display for presenting indicia to a user. The dispenser further comprises an outlet cover movable between a first position in which it covers the outlet and a second position in which the outlet is uncovered, wherein, when said outlet cover is in said first position, indicia is visible said display, and wherein, when said outlet cover is in said second poisition, indicia is out of sight to the user.
摘要翻译：本发明涉及一种药物包装分配器，例如吸入器。分配器包括用于分配药物的出口，例如喉舌或鼻接头。分配器还包括用于向用户呈现标记的显示器。所述分配器还包括可在其覆盖所述出口的第一位置和所述出口未被覆盖的第二位置之间移动的出口盖，其中当所述出口盖处于所述第一位置时，所述显示器可见标记，当所述出口盖处于所述第二取样时，标记对于使用者来说是不可见的。

8. 发明申请

WO2005038114A1 HALTERUNG FÜR EINE VORRICHTUNG ZUR QUALITÄTSÜBERWACHUNG AN EINER WEBMASCHINE 审中-公开
标题翻译： MOUNT对于质量控制的装置织机
公开(公告)号：WO2005038114A1
公开(公告)日：2005-04-28
申请号：PCT/CH2004/000624
申请日：2004-10-14
申请人： USTER TECHNOLOGIES AG , COOKE, Charles , GROOMBRIDGE, Chris , WALLER, Patrick
发明人： COOKE, Charles , GROOMBRIDGE, Chris , WALLER, Patrick
IPC分类号： D03J1/06
CPC分类号： D03J1/007 , D03D49/20 , D03J1/06 , D06H3/02
摘要： Es wird eine Vorrichtung (3) zur optischen Überwachung einer gewobenen Warenbahn (2) an einer Webmaschine (1) oder einer Umspulvorrichtung vorgeschlagen, die eine Halterung (5) umfasst und die sich über die gesamte Breite der gewobenen Warenbahn erstreckt. Die Überwachungsvorrichtung (3) ist direkt in Berührung mit der gewobenen Warenbahn (2) und wird im Bereich (6) zwischen einer Abzugswalze (30) und der Aufwicklung der Warenbahn (2) auf einen Warenbaum (10) oder eine Grossdocke parallel zu diesen, mittelbar mit der Webmaschine (1) verbunden gehalten. Die Halterung (5) besteht aus einer Achse (7) an der Überwachungsvorrichtung (3) und einer Achse (8) an der Webmaschine (1), wobei die beiden Achsen (7,8) parallel zueinander verlaufen und über einen Schwenkarm (9) miteinander verbunden sind.
摘要翻译：它提出了一种装置（3），用于（2）的织机（1）或复卷机，其包括支撑件（5）和延伸在所述织造布织物的整个宽度上以光学方式监测织造布织物。监视装置（3）直接与机织织物网（2）接触和牵引辊（30）之间，是在区域（6）的材料带（2）的上的布（10）或提升平行大的卷绕于此，间接地与织机（1），其连接保持。所述支撑件（5）由一轴（7），以监测装置（3）和在织机（1）的轴（8），其中，所述两个轴（7,8）彼此之间以及经由枢转臂平行延伸的（9）被连接在一起。

9. 发明申请

WO2002080725A1 BAG CLOSURE 审中-公开
标题翻译：袋封闭
公开(公告)号：WO2002080725A1
公开(公告)日：2002-10-17
申请号：PCT/GB2002/001047
申请日：2002-03-08
申请人： AQUAPAC INTERNATIONAL LIMITED , COOKE, Charles , MCCARTHY, Marc
发明人： COOKE, Charles , MCCARTHY, Marc
IPC分类号： A45C13/10
CPC分类号： A45C13/06 , A45C11/22
摘要： A bag closure for closing the opening of a bag defined by a pair of edges (5, 6) comprising two elongate members (1, 2) releasably connectable to each other with the edges of the bag clamped between the elongate members. A slider (4) is mounted on one of the elongate members. A cam surface (3) is provided on one of the elongate members. The movement of the slider (4) relative to the cam surface (3) causes the elongate members (1, 2) to be forced together, thereby clamping together the open edges of the bag. A bag including a closure, and a method of closing a bag using a closure is disclosed.
摘要翻译：用于封闭由一对边缘（5,6）限定的袋的开口的袋封闭件，包括两个细长构件（1,2），所述两个细长构件可释放地彼此连接，并且所述袋的边缘夹在细长构件之间。滑块（4）安装在细长构件中的一个上。凸轮表面（3）设置在一个细长构件上。滑动件（4）相对于凸轮表面（3）的运动导致细长构件（1,2）被压在一起，从而将袋的开口边缘夹紧在一起。公开了一种包括封闭物的袋子以及使用封盖封闭袋子的方法。

10. 发明授权

EP2334358B1 INHALATION DEVICE FOR DISPENSING MEDICAMENT 失效
标题翻译： INHALATIONSVORRICHTUNGFÜRMEDIKAMENTENAUSGABE
公开(公告)号：EP2334358B1
公开(公告)日：2016-02-10
申请号：EP09819487.1
申请日：2009-10-07
申请人： AstraZeneca AB
发明人： BAKEWELL, William , BRIANT, John , CAMPBELL, Patrick , JOHN, James Daniel , COOKE, Charles , GROOMBRIDGE, Christopher , SMARTT, Nicholas , LASTOW, Orest , HARRISON, Nicholas
IPC分类号： A61M15/00 , B65D83/04
CPC分类号： A61M15/0091 , A61M15/0003 , A61M15/0026 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/0093 , A61M15/0096 , A61M2202/064 , A61M2205/073

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