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1. 发明申请

WO2009102274A1 INHALER COMPRISING A BASE HAVING AT LEAST ONE SEALED CAVITY CONTAINING MEDICAMENT 审中-公开
标题翻译：吸入包含至少一个含有药物的密封囊的基底
公开(公告)号：WO2009102274A1
公开(公告)日：2009-08-20
申请号：PCT/SE2009/050141
申请日：2009-02-11
申请人： ASTRAZENECA AB , ARVIDSSON, Lars , BLAKEY, David , DAGSLAND, Allan , LASTOW, Orest , SIGGELIN, Lars
发明人： ARVIDSSON, Lars , BLAKEY, David , DAGSLAND, Allan , LASTOW, Orest , SIGGELIN, Lars
IPC分类号： A61M15/00 , B65D75/36 , B65D75/58
CPC分类号： A61M15/0045 , A61M15/0043 , A61M15/0048 , A61M15/0091 , A61M15/0096 , A61M2202/064
摘要： The invention relates to an inhaler, comprising a base having at least one sealed cavity containing medicament. A foil portion is attached to the base for sealing the medicament within the cavity. A separating element which is attached to the other side of the foil portion is provided for separating the foil portion from the cavity. The base has one or more geometrically distinguishable features for facilitating detachment of the foil portion from the base.
摘要翻译：本发明涉及一种吸入器，其包括具有至少一个包含药物的密封腔的底座。箔片部分连接到基座上，用于密封空腔内的药物。设置在箔片部分的另一侧上的分离元件用于将箔片部分与空腔分离。基座具有一个或多个几何可区分的特征，用于便于将箔部分与基部分离。

2. 发明申请

WO2010019102A1 DOSING DEVICE AND METHOD FOR FILLING A CAVITY 审中-公开
标题翻译：用于填充空穴的装置和方法
公开(公告)号：WO2010019102A1
公开(公告)日：2010-02-18
申请号：PCT/SE2009/050933
申请日：2009-08-13
申请人： ASTRAZENECA AB , DAGSLAND, Allan
发明人： DAGSLAND, Allan
IPC分类号： G01F11/10 , B65B1/24 , B65B1/36
CPC分类号： B65B1/363 , B65B1/24 , B65B37/20 , G01F11/40 , G01F11/46
摘要： The present invention relates to a dosing device (1) comprising a powder hopper (2) and a plate (11) with a surface (3), wherein said plate (11) is provided with at least one cavity (5) adapted for receiving a particulate material, and filling means (6) being movable along said surface (3) for moving particulate material into said at least one cavity (5), wherein said filling means (6) is adapted to exert a compressing force on said particulate material in a direction towards said surface (3) so that said particulate material is forced into said at least one cavity (5). The present invention also relates to a method for filling a cavity provided in a plate of a dosing device with a quantity of particulate material.
摘要翻译：本发明涉及一种包括粉末料斗（2）和具有表面（3）的板（11）的计量装置（1），其中所述板（11）设置有至少一个适于接收的空腔（5）颗粒材料和可沿着所述表面（3）移动的填充装置（6），用于将颗粒材料移动到所述至少一个空腔（5）中，其中所述填充装置（6）适于对所述颗粒材料施加压缩力在朝向所述表面（3）的方向上，使得所述颗粒材料被迫进入所述至少一个空腔（5）。本发明还涉及一种用于填充具有一定数量的颗粒材料的配量装置的板中的空腔的方法。

3. 发明申请

WO2007073302A1 NEW DEVICE 审中-公开
标题翻译：新设备
公开(公告)号：WO2007073302A1
公开(公告)日：2007-06-28
申请号：PCT/SE2006/001466
申请日：2006-12-21
申请人： ASTRAZENECA AB , DAGSLAND, Allan
发明人： DAGSLAND, Allan
IPC分类号： A61M15/00
CPC分类号： A61M15/00 , A61M11/002 , A61M15/0021 , A61M15/0065 , A61M2202/064 , A61M2206/14 , A61M2209/10
摘要： The present invention relates to a delivery device for administrating particulate medicaments, such as a dry powder inhaler. The delivery device comprises a body, a flow path comprising a chamber with an inlet and an outlet for the stream of air. The chamber is mounted rotatable in relation to the body. Dislodging means are arranged in contact with the inner surface of the chamber. The dislodging means and the chamber are relatively rotatable in relation to one another, such that the inside of the chamber is cleaned by the dislodging means when the dislodging means and the chamber are rotated in relation to one another. The invention further relates to a method for cleaning such a delivery device.
摘要翻译：本发明涉及一种用于施用颗粒药物的输送装置，例如干粉吸入器。输送装置包括主体，流路，其包括具有用于空气流的入口和出口的室。该腔室相对于身体可旋转地安装。移位装置布置成与腔室的内表面接触。移动装置和室相对于彼此相对可旋转，使得当移动装置和室相对于彼此旋转时，通过移动装置清洁室的内部。本发明还涉及清洁这种输送装置的方法。

4. 发明申请

WO2010071577A1 METHOD OF PROVIDING A TARGET DOSE, POWDER PROVIDER DEVICE AND ITS USE 审中-公开
标题翻译：提供目标剂量的方法，粉末提供者装置及其用途
公开(公告)号：WO2010071577A1
公开(公告)日：2010-06-24
申请号：PCT/SE2009/051429
申请日：2009-12-16
申请人： ASTRAZENECA AB , DAGSLAND, Allan
发明人： DAGSLAND, Allan
IPC分类号： G01F11/02 , A61M15/00 , B65B1/36 , B65B37/20 , G01F11/46
CPC分类号： G01F11/46 , A61J3/02 , A61J3/07 , B65B1/06 , B65B1/363 , B65B37/20
摘要： The invention relates to a method of providing in a powder provider device a target dose of an active pharmaceutical ingredient present in a powder preparation. The active ingredient in a powder sample is analysed and a powder volume corresponding to the target dose is calculated. The positions of wall portions forming a hole are adjusted relative to each other for receiving the calculated powder volume in the hole. The invention also relates to a method of providing a target volume of powder, a powder provider device and a use of a powder dosing system.
摘要翻译：本发明涉及在粉末提供者装置中提供存在于粉末制剂中的活性药物成分的目标剂量的方法。分析粉末样品中的活性成分，并计算与目标剂量相对应的粉末体积。形成孔的壁部的位置相对于彼此调节，以接收孔中计算出的粉末体积。本发明还涉及一种提供目标体积的粉末的方法，粉末提供器装置以及粉剂计量系统的用途。

5. 发明申请

WO2009029026A1 A METHOD FOR DOSING AND PROVIDING POWDER IN A POWDER PROVIDER, SUCH A POWDER PROVIDER DEVICE AND AN APPARATUS FOR PRODUCING PACKS 审中-公开
标题翻译：用于在粉末供应商中排粉和提供粉末的方法，例如粉末提供器装置和用于生产包装的装置
公开(公告)号：WO2009029026A1
公开(公告)日：2009-03-05
申请号：PCT/SE2008/050945
申请日：2008-08-22
申请人： ASTRAZENECA AB , DAGSLAND, Allan
发明人： DAGSLAND, Allan
IPC分类号： G01F11/02 , B65B1/36 , B65B37/20
CPC分类号： B65B1/363 , B65B37/20 , G01F11/46
摘要： It is disclosed a powder provider device (1) that comprises, a powder hopper (2) for pouring powder batches to a dosing system (3) that comprises a hole structure (4), wherein at least one hole (5) is formed by a surrounding wall structure. The wall structure is formed by wall portions that are movable relative to one 5 another, whereby the relative movement of wall portions, during handling of the powder, enables controlled dosing and pouring of the powder. Furthermore, it is disclosed an apparatus comprising said powder providing device and a method of dosing and providing powder in a powder provider device.
摘要翻译：公开了一种粉末供应器装置（1），其包括用于将粉末批料倾倒到包括孔结构（4）的定量给料系统（3）的粉末料斗（2），其中至少一个孔（5）由围墙结构。壁结构由相对于另一个可移动的壁部分形成，由此在粉末处理期间壁部分的相对运动使得能够控制粉末的计量和倾倒。此外，公开了一种包括所述粉末提供装置的装置和在粉末供应装置中配量和提供粉末的方法。

6. 发明公开

EP2379993A1 METHOD OF PROVIDING A TARGET DOSE, POWDER PROVIDER DEVICE AND ITS USE 审中-公开
标题翻译：程序对问题进行靶区剂量，粉末输出设备和及其用途
公开(公告)号：EP2379993A1
公开(公告)日：2011-10-26
申请号：EP09833740.5
申请日：2009-12-16
申请人： AstraZeneca AB
发明人： DAGSLAND, Allan
IPC分类号： G01F11/02 , A61M15/00 , B65B1/36 , B65B37/20 , G01F11/46
CPC分类号： G01F11/46 , A61J3/02 , A61J3/07 , B65B1/06 , B65B1/363 , B65B37/20
摘要： The invention relates to a method of providing in a powder provider device a target dose of an active pharmaceutical ingredient present in a powder preparation. The active ingredient in a powder sample is analysed and a powder volume corresponding to the target dose is calculated. The positions of wall portions forming a hole are adjusted relative to each other for receiving the calculated powder volume in the hole. The invention also relates to a method of providing a target volume of powder, a powder provider device and a use of a powder dosing system.

7. 发明公开

EP2185901A1 A METHOD FOR DOSING AND PROVIDING POWDER IN A POWDER PROVIDER, SUCH A POWDER PROVIDER DEVICE AND AN APPARATUS FOR PRODUCING PACKS 审中-公开
标题翻译：方法剂量，并在粉末分配器这种粉末捐赠设备提供粉末及其器具，用于产生PACKS
公开(公告)号：EP2185901A1
公开(公告)日：2010-05-19
申请号：EP08828395.7
申请日：2008-08-22
申请人： AstraZeneca AB
发明人： DAGSLAND, Allan
IPC分类号： G01F11/02 , B65B1/36 , B65B37/20
CPC分类号： B65B1/363 , B65B37/20 , G01F11/46
摘要： It is disclosed a powder provider device (1) that comprises, a powder hopper (2) for pouring powder batches to a dosing system (3) that comprises a hole structure (4), wherein at least one hole (5) is formed by a surrounding wall structure. The wall structure is formed by wall portions that are movable relative to one 5 another, whereby the relative movement of wall portions, during handling of the powder, enables controlled dosing and pouring of the powder. Furthermore, it is disclosed an apparatus comprising said powder providing device and a method of dosing and providing powder in a powder provider device.

8. 发明公开

EP1965848A1 NEW DEVICE 审中-公开
标题翻译：新设备
公开(公告)号：EP1965848A1
公开(公告)日：2008-09-10
申请号：EP06835881.1
申请日：2006-12-21
申请人： AstraZeneca AB
发明人： DAGSLAND, Allan
IPC分类号： A61M15/00
CPC分类号： A61M15/00 , A61M11/002 , A61M15/0021 , A61M15/0065 , A61M2202/064 , A61M2206/14 , A61M2209/10
摘要： A delivery device for administering particulate medicaments, such as dry powder. The delivery device comprises a body and a flow path comprising a chamber with an inlet and an outlet for the stream of air. The chamber is rotatable in relation to the body. Dislodging means are arranged in contact with the inner surface of the chamber. The dislodging means and the chamber are relatively rotatable in relation to one another, such that the inside of the chamber is cleaned by the dislodging means when the dislodging means and the chamber are rotated in relation to one another.

9. 发明授权

EP1007121B1 INHALATION DEVICE 失效
标题翻译：吸入装置
公开(公告)号：EP1007121B1
公开(公告)日：2003-06-11
申请号：EP98909948.6
申请日：1998-03-13
申请人： AstraZeneca AB
发明人： DAGSLAND, Allan , VIRTANEN, Risto
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0068 , A61M15/0075 , A61M2202/064
摘要： A powder inhaler and a method of constructing the same, the powder inhaler comprising: an inhaler body (6) having an opening (10) therein; an inhalation unit (22) disposed in the inhaler body (6), the inhalation unit (22) comprising an inhalation channel (24) through which powder is in use inhaled; a dosing unit (16) for providing a dose of powder to the inhalation channel (24) disposed in the inhaler body (6) so as to be rotatable about the central axis thereof, wherein the dosing unit (16) comprises a central shaft (20) which is co-axial with the central axis of the inhaler body (6) and has a spiral groove or protrusion (46) on the end face thereof; and an indicating wheel (42) for providing an indication as to the usage of the inhaler disposed in the inhaler body (6), the indicating wheel (42) having a toothed periphery (44) for engaging the spiral groove or protrusion (46) on the shaft (20) and being disposed such that at least a part thereof is visible through the opening (10) and so as to be rotatable within a diametrical plane containing the central axis of the inhaler body (6); characterized in that one side surface of the indicating wheel (42) includes at least one indication which is representative of the usage of the inhaler and in that the inhaler body (6) includes a recess (48) in which the opening (10) is provided, the opening (10) allowing at least a part of the one side surface of the indicating wheel (42) to be viewed.
摘要翻译： 1。一种粉末吸入器及其制造方法，所述粉末吸入器包括：其中具有开口（10）的吸入器主体（6）设置在吸入器主体（6）中的吸入单元（22），吸入单元（22）包括吸入通道（24），通过吸入通道吸入粉末; 给药单元（16），用于向设置在吸入器主体（6）中的吸入通道（24）提供一定剂量的粉末以便可绕其中心轴线旋转，其中给药单元（16）包括中心轴 20），其与吸入器主体（6）的中心轴线同轴并且在其端面上具有螺旋槽或突起（46）; 和指示轮（42），用于提供关于设置在吸入器主体（6）中的吸入器的使用的指示，指示轮（42）具有用于接合螺旋凹槽或凸起（46）的齿状周边（44）在所述轴（20）上并且被设置为使得其至少一部分通过所述开口（10）可见并且可在包含所述吸入器本体（6）的中心轴线的直径平面内旋转; 其特征在于，所述指示轮（42）的一个侧表面包括至少一个代表所述吸入器的使用的指示，并且所述吸入器主体（6）包括凹部（48），所述开口（10）在所述凹部设置允许观察指示轮（42）的一个侧表面的至少一部分的开口（10）。

10. 发明授权

EP1017438B1 INHALATION DEVICE 失效
标题翻译：吸入装置
公开(公告)号：EP1017438B1
公开(公告)日：2004-09-15
申请号：EP98909946.0
申请日：1998-03-13
申请人： AstraZeneca AB
发明人： ANDERSSON, Jan , CONWAY, John , DAGSLAND, Allan , FRIESS, Stefan , HECKENMUELLER, Harald , ROLLWAGE, Uwe , STRID, Hans , TIEDEMANN, Volker , TROFAST, Jan
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M11/002 , A61M15/0008 , A61M15/0068 , A61M15/0076 , A61M15/0086 , A61M2202/064 , A61M2206/14 , A61M2206/16
摘要： A powder inhaler for administering powder by inhalation, comprising: a flow path defined by a plurality of surfaces through which a stream of air is in use drawn on inhalation by a user; and dosing means (18) for providing a dose of powder to the flow path for entrainment in the stream of air; characterized in that the inhaler further comprises dislodging means for dislodging powder accumulated on a surface of the flow path downstream of the dosing means (18).
摘要翻译： 1。一种粉末吸入器，用于通过吸入给药粉末，包括：由多个表面限定的流动路径，当使用者吸入时吸入吸入的空气流通过所述多个表面; 和定量装置（18），用于向所述流动路径提供一定剂量的粉末以用于夹带在所述空气流中; 其特征在于，所述吸入器还包括用于排出积聚在定量给料装置（18）下游的流动路径表面上的粉末的排出装置。

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