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1. 发明申请

WO2007127841A3 COMPOSITIONS AND METHODS OF PREPARATION THEREOF 审中-公开
标题翻译：组合物及其制备方法
公开(公告)号：WO2007127841A3
公开(公告)日：2011-09-29
申请号：PCT/US2007067494
申请日：2007-04-26
申请人： ARTERIOCYTE MEDICAL SYSTEMS INC , YONCE LAURA A , KANAYINKAL TESSY , MULLINS-HIRTE DEBRA J , HUANG TREVOR C , CARIAPPA ROHIT , MERTE KENNETH E , KEOGH JAMES R , MCINTOSH KEVIN D , STEFFENS BRIAN J , NAYAK ASHA S , JOHNSON ERICK L
发明人： YONCE LAURA A , KANAYINKAL TESSY , MULLINS-HIRTE DEBRA J , HUANG TREVOR C , CARIAPPA ROHIT , MERTE KENNETH E , KEOGH JAMES R , MCINTOSH KEVIN D , STEFFENS BRIAN J , NAYAK ASHA S , JOHNSON ERICK L
IPC分类号： A61K38/36 , C07K14/745
CPC分类号： C12N9/6429 , A61K35/14 , A61K35/16 , A61K35/19 , C07K14/745 , C12N5/0644 , C12Y304/21005
摘要： The present invention provides biological compositions and methods for making the same.
摘要翻译：本发明提供了生物组合物及其制备方法。

2. 发明申请

WO2007127834A2 COMPOSITIONS AND METHODS OF PREPARATION THEREOF 审中-公开
公开(公告)号：WO2007127834A2
公开(公告)日：2007-11-08
申请号：PCT/US2007067486
申请日：2007-04-26
申请人： MEDTRONIC INC , YONCE LAURA A , KANAYINKAL TESSY , MULLINS-HIRTE DEBRA J , HUANG TREVOR C , CARIAPPA ROHIT , MERTE KENNETH E , KEOGH JAMES R , MCINTOSH KEVIN D , STEFFENS BRIAN J , NAYAK ASHA S , JOHNSON ERICK L
发明人： YONCE LAURA A , KANAYINKAL TESSY , MULLINS-HIRTE DEBRA J , HUANG TREVOR C , CARIAPPA ROHIT , MERTE KENNETH E , KEOGH JAMES R , MCINTOSH KEVIN D , STEFFENS BRIAN J , NAYAK ASHA S , JOHNSON ERICK L
CPC分类号： C12N9/6429 , A61K35/14 , A61K35/16 , A61K35/19 , C07K14/745 , C12N5/0644 , C12Y304/21005
摘要： The present invention provides biological compositions and methods for making the same.

3. 发明申请

WO2009052006A3 ARTERIAL BLOOD FILTER 审中-公开
标题翻译：动脉血液过滤器
公开(公告)号：WO2009052006A3
公开(公告)日：2009-06-04
申请号：PCT/US2008079325
申请日：2008-10-09
申请人： MEDTRONIC INC , HUANG TREVOR C , KALSCHEUER JOSEPH L , MCLEVISH ALFORD L , BRISCOE ROCERICK E
发明人： HUANG TREVOR C , KALSCHEUER JOSEPH L , MCLEVISH ALFORD L , BRISCOE ROCERICK E
IPC分类号： A61M1/36 , B01D19/00
CPC分类号： B01D19/0057 , A61M1/3633 , A61M2206/10 , A61M2206/16
摘要： An arterial line blood filter for use in extracorporeal blood circuits during heart bypass surgery has, among other components, a housing (12) with a cap portion (14), a base portion (18), and a generally cylindrical wall portion (16). The blood filter has a filter element disposed within the housing. An inlet is positioned at an upward angle with respect to the housing and includes an opening in the generally cylindrical wall portion in fluid communication with the inlet chamber. In some embodiments the position of the inlet limits the pressure drop and prime volume of the filter. According to one embodiment, the cap portion has an upwardly sloping inner surface and there is a vent (32) in the cap portion. The inner surface of the cap portion can have a projection proximate the vent configured to limit immobilization of gaseous microemboli within the inlet chamber.
摘要翻译：在心脏旁路手术期间用于体外血液循环的动脉血液过滤器除了其它部件之外还具有具有盖部分（14），基部（18）和大致圆柱形壁部分（16）的壳体（12）。血液过滤器具有设置在壳体内的过滤元件。入口相对于壳体以向上的角度定位，并且在大致圆柱形壁部分中包括与入口室流体连通的开口。在一些实施例中，入口的位置限制了过滤器的压降和原始体积。根据一个实施例，盖部分具有向上倾斜的内表面，并且在帽部分中具有通气口（32）。帽部分的内表面可以具有靠近通气口的突出部，其构造成限制气体微栓塞在入口室内的固定。

4. 发明申请

WO2008063759A3 A METHOD OF INCREASING RETENTION, SURVIVAL AND PROLIFERATION OF TRANSPLANTED CELLS IN VIVO 审中-公开
标题翻译：一种提高体内移植细胞的保留，存活和增殖的方法
公开(公告)号：WO2008063759A3
公开(公告)日：2008-11-06
申请号：PCT/US2007080428
申请日：2007-10-04
申请人： MEDTRONIC INC , FERNANDES BRIAN , SCHU CARL A , HUANG TREVOR C , DONOVAN MAURA G
发明人： FERNANDES BRIAN , SCHU CARL A , HUANG TREVOR C , DONOVAN MAURA G
IPC分类号： A01N63/00 , C12N5/071
CPC分类号： A61L27/3839 , A61K35/16 , A61K35/19 , A61K35/34 , A61L27/3886 , C12N5/0068 , C12N5/0691 , C12N2533/90 , A61K2300/00
摘要： A method of increasing retention, survival and proliferation of transplanted cells in diseased or damaged tissue types or organ by providing transplanted cells with autologously-derived platelet cells and forming a autologously-derived platelet gel prior or during administration to the tissue type or organ through a delivery device and immobilizing the transplanted cells in the tissue type or organ system.
摘要翻译：通过向移植细胞提供自体衍生的血小板细胞并在施用于组织类型或器官之前或期间通过提供自体衍生的血小板凝胶来增加移植细胞在患病或受损组织类型或器官中的保留，存活和增殖的方法输送装置并将移植细胞固定在组织类型或器官系统中。

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