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1. 发明申请

WO2008103534A3 SELECTIVELY REINFORCED MEDICAL DEVICES 审中-公开
标题翻译：选择性增强医疗设备
公开(公告)号：WO2008103534A3
公开(公告)日：2008-10-16
申请号：PCT/US2008052815
申请日：2008-02-01
申请人： ARROW INT INC , ROSENBLATT JOEL , STARSINIC MICHAEL E , DO HIEP
发明人： ROSENBLATT JOEL , STARSINIC MICHAEL E , DO HIEP
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61M25/0029 , A61M2025/0031 , A61M2025/0037
摘要： A medical device including a component made of polyurethane having a reinforced pattern comprising polytetramethylene ether glycol.
摘要翻译：一种医疗装置，其包括由具有包含聚四亚甲基醚二醇的增强图案的聚氨酯制成的部件。

2. 发明申请

WO2008060380A3 ANTI-INFECTIVE ALCOHOL CATHETER SOLUTION WITH CHLORHEXIDINE TREATED CATHETER 审中-公开
标题翻译：用氯化氢处理的导管的抗感染酒精导管溶液
公开(公告)号：WO2008060380A3
公开(公告)日：2008-10-30
申请号：PCT/US2007021835
申请日：2007-10-12
申请人： ARROW INT INC , ROSENBLATT JOEL , SPANGLER DANIEL J , MOSS SHANNA
发明人： ROSENBLATT JOEL , SPANGLER DANIEL J , MOSS SHANNA
IPC分类号： A61F2/00
CPC分类号： A61L29/16 , A61L2300/206 , A61L2300/404 , A61L2300/442 , A61L2300/45 , A61L2300/606 , A61M25/0017
摘要： Implantable catheters treated with chlorhexidine and methods for disinfecting the catheters with alcohol are provided.
摘要翻译：提供用氯己定处理的植入式导管和用酒精消毒导管的方法。

3. 发明申请

WO2007064835A3 CATHETER WITH POLYMERIC COATING 审中-公开
标题翻译：带聚合物涂层的导管
公开(公告)号：WO2007064835A3
公开(公告)日：2007-10-18
申请号：PCT/US2006045918
申请日：2006-12-01
申请人： ARROW INT INC , ROSENBLATT JOEL , VITULLO JEFF , BOUCHARD MIKE
发明人： ROSENBLATT JOEL , VITULLO JEFF , BOUCHARD MIKE
IPC分类号： A61M31/00
CPC分类号： A61L29/16 , A61L2300/206 , A61L2300/404 , A61M25/007 , A61M2025/0056
摘要： A catheter including a main body having a first end, a second end, a lumen extending between the first end and the second end, a first section located proximal the first end of the main body and second section located proximal the second end of the main body. An inhibitory polymer is disposed at the first section. The inhibitory polymer includes one or more members selected from the group consisting of antiproliferatives, antithrombotics, thrombolytics, and fibrinolytics. An antimicrobial agent is disposed at the second section. The main body has a length such that when the catheter is at least partially implanted the first end accesses a body vessel and at least a portion of the second section is disposed within a subcutaneous space of a patient.
摘要翻译：一种包括主体的导管，其具有第一端，第二端，在所述第一端和所述第二端之间延伸的内腔，位于所述主体的第一端附近的第一部分和位于所述主体的第二端附近的第二部分身体。在第一部分设置抑制性聚合物。抑制性聚合物包括选自抗增生剂，抗血栓药，溶栓剂和纤维蛋白溶解剂中的一种或多种。抗微生物剂设置在第二部分。主体具有这样的长度，使得当导管至少部分植入时，第一端进入体血管，并且第二部分的至少一部分设置在患者的皮下空间内。

4. 发明专利

AU2002353762A1 Immune modulation device for use in animals 未知
公开(公告)号：AU2002353762A1
公开(公告)日：2003-03-18
申请号：AU2002353762
申请日：2002-05-09
申请人： KOYFMAN ILYA S , ROSENBLATT JOEL , TENHUISEN KEVOR S , APPLIED VACCINE TECHNOLOGIES C
发明人： XIE QIAO-WEN , TENHUISEN KEVOR S , CERAMI ANTHONY , ROSENBLATT JOEL , KOYFMAN ILYA S , CERAMI CARLA
IPC分类号： A61K9/00 , A61K9/16 , C12N5/06 , C12Q1/06 , C07K14/00 , G01N33/543 , G01N33/53 , A61K39/00 , A61K35/14 , A61K38/00
摘要： The present invention is directed to an implantable immune modulation device that is useful for modulating an immune response in mammals, comprising a plurality of fibers, within a porous shell. The fiber filling is loaded with single or multiple antigens, and optionally one or more biologically active compounds such as cytokines (e.g. lymphokines, chemokines etc.), attachment factors, genes, peptides, proteins, nucleotides, carbohydrates or cells depending on the application.

5. 发明申请

WO2008054772A3 IMPLANTABLE ELASTOMERIC CAPROLACTONE DEPOT COMPOSITIONS AND USES THEREOF 审中-公开
标题翻译：可植入弹性CAPROLACTONE储库组合物及其用途
公开(公告)号：WO2008054772A3
公开(公告)日：2008-11-27
申请号：PCT/US2007022983
申请日：2007-10-31
申请人： ALZA CORP , CHEN GUOHUA , KLEINER LOTHAR WALTER , HOUSTON PAUL R , NATHAN ARUNA , ROSENBLATT JOEL
发明人： CHEN GUOHUA , KLEINER LOTHAR WALTER , HOUSTON PAUL R , NATHAN ARUNA , ROSENBLATT JOEL
IPC分类号： A61K9/00 , A61F2/00 , A61L31/14 , A61L31/16
CPC分类号： A61K9/0024
摘要： Methods and compositions for systemically or locally administering a beneficial agent to a subject are described, and include, for example, implantable elastomeric depot compositions that can be injected into a desired location and which can provide controlled release of a beneficial agent over a prolonged duration of time. The compositions include a biocompatible, elastomeric caprolactone copolymer, a biocompatible solvent having low water miscibility that forms an elastomeric viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
摘要翻译：描述了用于向受试者全身或局部施用有益物质的方法和组合物，并且包括例如可植入的弹性体储库组合物，其可以注射到期望的位置并且可以在延长的持续时间内提供有益物质的受控释放时间。该组合物包括生物相容的弹性体己内酯共聚物，具有低水混溶性的生物相容性溶剂，其与聚合物形成弹性粘性凝胶并限制植入物对水的吸收，以及有益剂。

6. 发明公开

EP2160152A4 COMBINED FIBRINOLYTIC AND ANTIMICROBIAL CATHETER AND USES THEREOF 有权
标题翻译：联合纤维蛋白溶解和抗菌导管及其用途
公开(公告)号：EP2160152A4
公开(公告)日：2011-08-10
申请号：EP08754605
申请日：2008-05-21
申请人： ARROW INT INC
发明人： GUPTA NISHA , ROSENBLATT JOEL , SPANGLER DANIEL J
IPC分类号： A61F2/06
CPC分类号： A61L29/16 , A61L33/0047 , A61L2300/206 , A61L2300/404 , A61L2300/406 , A61L2300/42 , A61L2300/442 , A61L2300/45 , A61M2025/0056
摘要： Implantable catheters are provided which comprise an antimicrobial agent incorporated in a coating or bulk distributed, in combination with a fibrinolytic agent incorporated in a top coating.

7. 发明公开

EP2197402A4 HIGH CONCENTRATION GENTIAN VIOLET CONTAINING MEDICAL DEVICES AND METHODS OF MAKING SAME 审中-公开
标题翻译：与高浓度结晶紫医疗VORICHTUNGEN用于生产
公开(公告)号：EP2197402A4
公开(公告)日：2011-08-03
申请号：EP08836117
申请日：2008-10-02
申请人： ARROW INT INC
发明人： DO HIEP , SPANGLER DANIEL J , ROSENBLATT JOEL , REMINGTON BARRETT , OKOH ONAJITE
IPC分类号： A61F13/00 , A61L29/16
CPC分类号： A61L29/14 , A61L29/06 , A61L29/16 , A61L2300/404 , A61L2300/442 , C08L75/04

8. 发明公开

EP2079395A4 ANTI-INFECTIVE ALCOHOL CATHETER SOLUTION WITH CHLORHEXIDINE TREATED CATHETER 审中-公开
标题翻译：酒精抗传染性解导管和洗必泰经处理导管
公开(公告)号：EP2079395A4
公开(公告)日：2011-08-03
申请号：EP07867223
申请日：2007-10-12
申请人： ARROW INT INC
发明人： ROSENBLATT JOEL , SPANGLER DANIEL J , MOSS SHANNA
IPC分类号： A61F2/00
CPC分类号： A61L29/16 , A61L2300/206 , A61L2300/404 , A61L2300/442 , A61L2300/45 , A61L2300/606 , A61M25/0017

9. 发明申请

WO03020161A3 IMMUNE MODULATION DEVICE FOR USE IN ANIMALS 审中-公开
标题翻译：用于动物的免疫调节装置
公开(公告)号：WO03020161A3
公开(公告)日：2003-06-05
申请号：PCT/US0214759
申请日：2002-05-09
申请人： APPLIED VACCINE TECHNOLOGIES C , CERAMI ANTHONY , CERAMI CARLA , XIE QIAO-WEN , TENHUISEN KEVOR S , ROSENBLATT JOEL , KOYFMAN ILYA S
发明人： CERAMI ANTHONY , CERAMI CARLA , XIE QIAO-WEN , TENHUISEN KEVOR S , ROSENBLATT JOEL , KOYFMAN ILYA S
IPC分类号： A61K9/00 , A61K9/16 , A61K35/14 , A61K38/00 , A61K39/00 , C07K14/00 , C12N5/06 , C12Q1/06 , G01N33/53 , G01N33/543 , A61K45/05
CPC分类号： A61K9/0024 , A61K9/1641 , A61K9/1647 , Y10T442/2525
摘要： The present invention is directed to an implantable immune modulation device (Figure 1) that is useful for modulating an immune response in mammals, comprising a plurality of fibers, within a porous shell. The fiber filling is loaded with single or multiple antigens, and optionally one or more biologically active compounds such as cytokines (e.g. lymphokines, chemokines etc.), attachment factors, genes, peptides, proteins, nucleotides, carbohydrates or cells depending on the application.
摘要翻译：本发明涉及可用于在多孔壳内调节包含多种纤维的哺乳动物的免疫应答的可植入免疫调节装置（图1）。取决于应用，纤维填充物装载有单个或多个抗原，以及任选地一种或多种生物活性化合物，例如细胞因子（例如淋巴因子，趋化因子等），附着因子，基因，肽，蛋白质，核苷酸，碳水化合物或细胞。

10. 发明公开

EP2205293A4 COMBINATION OF ALCOHOL LOCK AND GENTIAN VIOLET CATHETER 审中-公开
标题翻译：显示酒精合并阻滞剂和结晶紫封管
公开(公告)号：EP2205293A4
公开(公告)日：2011-08-03
申请号：EP08835142
申请日：2008-10-02
申请人： ARROW INT INC
发明人： STEINKE ELAINE MARTHA , SPANGLER DANIEL J , ROSENBLATT JOEL
IPC分类号： A61L33/00
CPC分类号： A61L29/14 , A61L29/16 , A61L2300/404 , A61L2300/442 , A61M27/008 , A61M2025/0056

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