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1. 发明申请

WO2008018904A2 SYSTEMS AND METHODS FOR PROCESSING SAMPLES IN A CLOSED CONTAINER, AND RELATED DEVICES 审中-公开
标题翻译：在封闭容器中处理样品的系统和方法以及相关设备
公开(公告)号：WO2008018904A2
公开(公告)日：2008-02-14
申请号：PCT/US2007001170
申请日：2007-01-17
申请人： ARGOS THERAPEUTICS INC , KIRIN BREWERY , SPENCE SIMON JONATHON , GRANT RICHARD ALEXANDER , PEELE TIMOTHY DOYLE , HUNTER WILLIAM SAMUEL , ABDELMOTELEB ASHRAF F , KNEEN DAVID THOMAS , NEIL ROBERT ALISTER , HARRIS SIMON
发明人： SPENCE SIMON JONATHON , GRANT RICHARD ALEXANDER , PEELE TIMOTHY DOYLE , HUNTER WILLIAM SAMUEL , ABDELMOTELEB ASHRAF F , KNEEN DAVID THOMAS , NEIL ROBERT ALISTER , HARRIS SIMON
IPC分类号： C12M3/00
CPC分类号： G01N35/0099 , B01L1/00 , B01L1/02 , B01L3/021 , B01L3/0293 , B01L3/5085 , B01L7/52 , B01L9/06 , B01L9/523 , B01L2200/02 , B01L2200/0642 , B01L2200/142 , B01L2300/046 , B01L2300/06 , B01L2300/0838 , B01L2300/123 , B01L2400/0481 , G01L1/00 , G01N1/34 , G01N35/00732 , G01N35/00871 , G01N2021/0378 , Y10T436/11 , Y10T436/2575
摘要： A system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and/or other sample manipulation device can be attached to the inside of the barrier, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device. The barrier can be flexible, and allow the robotic arm to move the pipette head throughout the work area of the tray. All samples, reagents, pipette tips and other tools or devices for processing nucleic acid samples may remain within the closed compartment provided by the container during processing.
摘要翻译：用于核酸和其它样品的自动处理的系统和方法包括一个包含托盘和柔性屏障的一次性容器。阻挡件被构造成与托盘的顶部边缘密封，在密封托盘内提供封闭的无菌工作区域。移液管头和/或其他样品操纵装置可以附接到屏障的内部，并且屏障可以包括用于机器臂或其它装置的界面。当屏障被密封在托盘上时，屏障将托盘的内容物与机器人或其他操纵装置分开。障碍物可以是柔性的，并且允许机器人臂将移液管头移动到托盘的整个工作区域。用于处理核酸样品的所有样品，试剂，移液器吸头和其他工具或装置可以在处理期间保留在由容器提供的封闭隔室内。

2. 发明专利

AU2007282135A1 Systems and methods for processing samples in a closed container, and related devices 未知
公开(公告)号：AU2007282135A1
公开(公告)日：2008-02-14
申请号：AU2007282135
申请日：2007-01-17
申请人： ARGOS THERAPEUTICS INC , KIRIN BREWERY
发明人： ABDELMOTELEB ASHRAF F , NEIL ROBERT ALISTER , HUNTER WILLIAM SAMUEL , SPENCE SIMON JONATHON , HARRIS SIMON , GRANT RICHARD ALEXANDER , PEELE TIMOTHY DOYLE , KNEEN DAVID THOMAS
IPC分类号： C12M3/00
摘要： Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.

3. 发明申请

WO2007106552A3 SYSTEM AND METHOD FOR DIAGNOSIS OF INFECTIOUS DISEASES 审中-公开
标题翻译：感染性疾病诊断系统及方法
公开(公告)号：WO2007106552A3
公开(公告)日：2007-11-29
申请号：PCT/US2007006521
申请日：2007-03-14
申请人： MICRONICS INC , HUNTER WILLIAM SAMUEL
发明人： HUNTER WILLIAM SAMUEL
IPC分类号： B01L3/00 , A61B10/00
CPC分类号： B01F13/0059 , A61B10/0045 , A61B10/0051 , A61B10/0096 , B01F13/0818 , B01L3/502715 , B01L3/5029 , B01L7/52 , B01L9/527 , B01L2200/027 , B01L2200/10 , B01L2300/0627 , B01L2300/1805 , B01L2300/1827 , B01L2300/185 , B01L2400/0683 , G01N2001/028
摘要： A biosafe apparatus is disclosed for assay and diagnosis of respiratory pathogens comprising a nasal sampling device, a single entry, disposable microfluidic cartridge for target nucleic acid amplification, and an instrument with on-board assay control platform and target detection means.
摘要翻译：公开了用于呼吸道病原体的测定和诊断的生物安全装置，其包括鼻取样装置，用于靶核酸扩增的单入口，一次性微流体盒，以及具有板载测定控制平台和目标检测装置的仪器。

4. 发明申请

WO2008134811A1 A PORTABLE DEVICE FOR READING A FLUORESCENT-LABELLED, MEMBRANE BASED ARRAY 审中-公开
标题翻译：用于读取荧光标记的基于膜的阵列的便携式设备
公开(公告)号：WO2008134811A1
公开(公告)日：2008-11-13
申请号：PCT/AU2008000622
申请日：2008-05-02
申请人： FLUIDYX PTY LTD , HUNTER WILLIAM SAMUEL , HOPPER WILLIAM ROBB
发明人： HUNTER WILLIAM SAMUEL , HOPPER WILLIAM ROBB
IPC分类号： G01N21/77 , A61B5/00
CPC分类号： G01N21/6428 , G01N21/645 , G01N21/8483 , G01N35/00693 , G01N2021/6484 , G01N2201/0221
摘要： The invention concerns a portable device for reading a fluorescent-labelled, membrane based assay, to detect the presence of an analyte in a sample. The portable device comprises a light sealed housing which includes a receiving member to receive a membrane based assay. The light sealed housing comprises a first light source for illuminating a first portion of the membrane with light, a first photodetector, a light guide and a microprocessor. The first photodetector is operable to detect fluoresced light emitted by an excited fluorescent label captured by a reagent laid down in the first portion of the membrane and to measure an intensity of the fluoresced light. The light guide guides illuminated light from the first light source to the first portion of the membrane and guides fluoresced light emitted by the excited fluorescent label to the first photodetector. The microprocessor is operable to process the measured intensity of the fluoresced light to determine whether the analyte is present.
摘要翻译：本发明涉及用于读取荧光标记的基于膜的测定法以检测样品中分析物的存在的便携式设备。便携式装置包括一个光密封的外壳，它包括一个用于接收基于膜的测定的接收构件。光密封壳体包括用于用光照亮膜的第一部分的第一光源，第一光电检测器，光导和微处理器。第一光电检测器可操作以检测由放置在膜的第一部分中的试剂捕获的激发的荧光标记发射的荧光，并测量荧光的强度。光引导件将来自第一光源的光照射到膜的第一部分，并将由激发的荧光标记发射的荧光的光引导到第一光电检测器。微处理器可操作地处理所测量的荧光的强度以确定分析物是否存在。

5. 发明专利

CA2635268C SYSTEMS AND METHODS FOR PROCESSING SAMPLES IN A CLOSED CONTAINER, AND RELATED DEVICES 未知
公开(公告)号：CA2635268C
公开(公告)日：2021-02-16
申请号：CA2635268
申请日：2007-01-17
申请人： ARGOS THERAPEUTICS INC , KIRIN PHARMA KK
发明人： SPENCE SIMON JONATHON , GRANT RICHARD ALEXANDER , PEELE TIMOTHY DOYLE , HUNTER WILLIAM SAMUEL , ABDELMOTELEB ASHRAF F , KNEEN DAVID THOMAS , NEIL ROBERT ALISTER , HARRIS SIMON
IPC分类号： C12M3/00
摘要： A system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and/or other sample manipulation device can be attached to the inside of the barrier, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device. The barrier can be flexible, and allow the robotic arm to move the pipette head throughout the work area of the tray. All samples, reagents, pipette tips and other tools or devices for processing nucleic acid samples may remain within the closed compartment provided by the container during processing.

6. 发明专利

AU2007282135A8 Systems and methods for processing samples in a closed container, and related devices 未知
公开(公告)号：AU2007282135A8
公开(公告)日：2008-07-17
申请号：AU2007282135
申请日：2007-01-17
申请人： ARGOS THERAPEUTICS INC , KIRIN PHARMA KK
发明人： ABDELMOTELEB ASHRAF F , NEIL ROBERT ALISTER , HUNTER WILLIAM SAMUEL , SPENCE SIMON JONATHON , HARRIS SIMON , GRANT RICHARD ALEXANDER , PEELE TIMOTHY DOYLE , KNEEN DAVID THOMAS
IPC分类号： C12M3/00
摘要： Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.

7. 发明专利

CA2635268A1 SYSTEMS AND METHODS FOR PROCESSING SAMPLES IN A CLOSED CONTAINER, AND RELATED DEVICES 未知
公开(公告)号：CA2635268A1
公开(公告)日：2008-02-14
申请号：CA2635268
申请日：2007-01-17
申请人： KIRIN PHARMA KK , ARGOS THERAPEUTICS INC
发明人： NEIL ROBERT ALISTER , ABDELMOTELEB ASHRAF F , KNEEN DAVID THOMAS , HARRIS SIMON , SPENCE SIMON JONATHON , HUNTER WILLIAM SAMUEL , GRANT RICHARD ALEXANDER , PEELE TIMOTHY DOYLE
IPC分类号： C12M3/00
摘要： Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.

8. 发明专利

GB189907850A Improvements in Muzzles for Horses and the like. 未知
公开(公告)号：GB189907850A
公开(公告)日：1900-03-17
申请号：GB189907850D
申请日：1899-04-14
申请人： HUNTER WILLIAM , HUNTER WILLIAM SAMUEL , HUNTER SAMUEL THOMAS
发明人： HUNTER WILLIAM , HUNTER WILLIAM SAMUEL , HUNTER SAMUEL THOMAS
摘要： 7850. Hunter, W., Hunter, W. S., and Hunter, S. T. April 14. Muzzles for animals; saddles.-Muzzles for horses &c. are made from a sheet of leather cut to the form shown in Fig. 1 and then folded, riveted, &c. and blocked to the form shown in Fig. 2, where b, bare openings opposite the nostrils. Buckets and leather sockets for carbines &c. may be similarly made without a bottom seam.

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