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1. 发明专利

AU2012392187B2 Method of weight management 未知
公开(公告)号：AU2012392187B2
公开(公告)日：2018-07-12
申请号：AU2012392187
申请日：2012-11-06
申请人： ARENA PHARM INC , SANCHEZ MATILDE , SHANAHAN WILLIAM R
发明人： SANCHEZ MATILDE , SHANAHAN WILLIAM R
IPC分类号： A61K31/55 , A61P3/04
摘要： Provided are methods of determining if an individual is a responder to treatment with (

2. 发明专利

CA2886875A1 METHOD OF WEIGHT MANAGEMENT 未知
公开(公告)号：CA2886875A1
公开(公告)日：2014-04-17
申请号：CA2886875
申请日：2012-11-06
申请人： ARENA PHARM INC , SANCHEZ MATILDE , SHANAHAN WILLIAM R
发明人： SANCHEZ MATILDE , SHANAHAN WILLIAM R
IPC分类号： A61K31/55 , A61P3/04
摘要： Provided are methods of determining if an individual is a responder to treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof. Also provided are methods for selecting an individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof from a plurality of individuals in need of weight management. Also provided are methods for weight management in an individual in need thereof. Also provided are compounds, compositions, and kits for use in a method of weight management in an individual.

3. 发明专利

AU2012392187A1 Method of weight management 未知
公开(公告)号：AU2012392187A1
公开(公告)日：2015-04-23
申请号：AU2012392187
申请日：2012-11-06
申请人： ARENA PHARM INC , SHANAHAN WILLIAM , SANCHEZ MATILDE
发明人： SANCHEZ MATILDE , SHANAHAN WILLIAM R
IPC分类号： A61K31/55 , A61P3/04
摘要： Provided are methods of determining if an individual is a responder to treatment with (

4. 发明申请

WO2004052309A3 MODULATION OF STAT 6 EXPRESSION 审中-公开
标题翻译： STAT 6表达调控
公开(公告)号：WO2004052309A3
公开(公告)日：2005-04-28
申请号：PCT/US0339492
申请日：2003-12-11
申请人： ISIS PHARMACEUTICALS INC , SHANAHAN WILLIAM R , FREIER SUSAN M , DOBIE KENNETH W
发明人： SHANAHAN WILLIAM R , FREIER SUSAN M , DOBIE KENNETH W
IPC分类号： C07H21/04 , C12N15/113 , C12Q1/68 , A01N43/04 , A61K31/70 , C12N5/00
CPC分类号： C12N15/113 , C07H21/04 , C12N2310/11 , C12N2310/315 , C12N2310/321 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12Q1/6886 , C12Q2600/136 , C12Q2600/16 , C12N2310/3525
摘要： Compounds, compositions and methods are provided for modulating the expression of STAT 6. The compositions comprise oligonucleotides, targeted to nucleic acid encoding STAT 6. Methods of using these compounds for modulation of STAT 6 expression and for diagnosis and treatment of disease associated with expression of STAT 6 are provided.
摘要翻译：提供化合物，组合物和方法用于调节STAT6的表达。组合物包含靶向编码STAT6的核酸的寡核苷酸。使用这些化合物调节STAT6表达并用于诊断和治疗与表达相关的疾病提供STAT 6。

5. 发明专利

AU2016205361A1 Methods of treating conditions related to the S1P1 receptor 未知
公开(公告)号：AU2016205361A1
公开(公告)日：2017-08-17
申请号：AU2016205361
申请日：2016-01-06
申请人： ARENA PHARM INC
发明人： GLICKLICH ALAN , KAM MARIA MATILDE SANCHEZ , SHANAHAN WILLIAM R
IPC分类号： A61K31/473 , A61P29/00 , A61P37/00
摘要： Provided are methods of treatment of a sphingosine 1-phosphate subtype 1 (S1P

6. 发明专利

AU2016200860A1 Administration of lorcaserin to individuals with renal impairment 未知
公开(公告)号：AU2016200860A1
公开(公告)日：2016-02-25
申请号：AU2016200860
申请日：2016-02-10
申请人： ARENA PHARM INC
发明人： ANDERSON CHRISTEN M , SHANAHAN WILLIAM R
IPC分类号： A61K31/55 , A61P3/04
摘要： The present disclosure relates to methods for weight management in an individual in need thereof by 5 determining the level of renal sufficiency of the individual and prescribing or administering a therapeutically effective amount of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof to the individual, provided that the individual has a level of renal sufficiency selected from the group consisting of: no renal impairment, mild renal impairment, and moderate renal impairment. In addition, the disclosure relates to a method 10 for selecting an individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3 benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof from a plurality of individuals in need of weight management by determining the level of renal sufficiency of the individual and selecting the individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro 1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof if the individual 15 has a level of renal sufficiency selected from the group consisting of: no renal impairment, mild renal impairment, and moderate renal impairment.

7. 发明专利

MX2015004532A METODO DE CONTROL DEL PESO. 未知
公开(公告)号：MX2015004532A
公开(公告)日：2016-01-20
申请号：MX2015004532
申请日：2012-11-06
申请人： ARENA PHARM INC
发明人： SANCHEZ MATILDE , SHANAHAN WILLIAM R
IPC分类号： A61K31/55 , A61P3/04
摘要： Se proporcionan métodos para determinar si una persona responde a un tratamiento con (R)-8-cloro-l-metil-2,3,4,5-tetrahidro-1 H-3-benzacepina o una sal, solvato o hidrato farmacéuticamente aceptable del mismo. También se proporcionan métodos para seleccionar a un individuo para el tratamiento con (R)-8-cloro-I-metil-2,3,4,5-tetrahidro-1H-3-benzacepina o una sal, solvato o hidrato farmacéuticamente aceptable del mismo, de una pluralidad de individuos con necesidad de tratamiento de control de peso. También se proporcionan métodos para el manejo de un tratamiento de control de peso para un individuo con necesidad del mismo. También se proporcionan compuestos, composiciones y estuches para usarse en el manejo de control de peso en individuo.

8. 发明专利

SG10201506896RA ADMINISTRATION OF LORCASERIN TO INDIVIDUALS WITH RENAL IMPAIRMENT 未知
公开(公告)号：SG10201506896RA
公开(公告)日：2015-10-29
申请号：SG10201506896R
申请日：2011-08-31
申请人： ARENA PHARM INC
发明人： ANDERSON CHRISTEN M , SHANAHAN WILLIAM R

9. 发明专利

PH12015500733A1 METHOD OF WEIGHT MANAGEMENT 未知
公开(公告)号：PH12015500733A1
公开(公告)日：2015-06-01
申请号：PH12015500733
申请日：2015-04-01
申请人： ARENA PHARM INC
发明人： MATILDE SANCHEZ , SHANAHAN WILLIAM R
IPC分类号： A61K31/55 , A61P3/04
摘要： Provided are methods of determining if an individual is a responder to treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof. Also provided are methods for selecting an individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof from a plurality of individuals in need of weight management. Also provided are methods for weight management in an individual in need thereof. Also provided are compounds, compositions, and kits for use in a method of weight management in an individual.

10. 发明专利

AU2011296015A1 Administration of lorcaserin to individuals with renal impairment 未知
公开(公告)号：AU2011296015A1
公开(公告)日：2013-04-04
申请号：AU2011296015
申请日：2011-08-31
申请人： ARENA PHARM INC
发明人： ANDERSON CHRISTEN M , SHANAHAN WILLIAM R
IPC分类号： A61K31/55 , A61P3/04
摘要： The present disclosure relates to methods for weight management in an individual in need thereof by determining the level of renal sufficiency of the individual and prescribing or administering a therapeutically effective amount of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof to the individual, provided that the individual has a level of renal sufficiency selected from the group consisting of: no renal impairment, mild renal impairment, and moderate renal impairment. In addition, the disclosure relates to a method for selecting an individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof from a plurality of individuals in need of weight management by determining the level of renal sufficiency of the individual and selecting the individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof if the individual has a level of renal sufficiency selected from the group consisting of: no renal impairment, mild renal impairment, and moderate renal impairment.

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