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1. 发明申请

WO2007149910A2 PROSTHETIC HEART VALVES, SUPPORT STRUCTURES AND SYSTEMS AND METHODS FOR IMPLANTING THE SAME 审中-公开
标题翻译：前置心脏瓣膜，支撑结构和系统及其插入方法
公开(公告)号：WO2007149910A2
公开(公告)日：2007-12-27
申请号：PCT/US2007/071652
申请日：2007-06-20
申请人： AORTX, INC. , FORSTER, David, C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott
发明人： FORSTER, David, C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2250/0036 , C07K16/30 , C07K16/40 , C07K2317/622
摘要： Described herein are systems and methods for operation of a prosthetic valve support structure. Described embodiments include, but are not limited to, multi-layer support structures, support structures having variable thicknesses, device for facilitating deflection of portions of support structures, and hinges for use with support structures.
摘要翻译：本文描述了用于操作人造瓣膜支撑结构的系统和方法。描述的实施例包括但不限于多层支撑结构，具有可变厚度的支撑结构，用于促进支撑结构的部分的偏转的装置，以及用于支撑结构的铰链。

2. 发明申请

WO2007149905A2 PROSTHETIC VALVE IMPLANT SITE PREPARATION TECHNIQUES 审中-公开
标题翻译：推进阀门植入物制备技术
公开(公告)号：WO2007149905A2
公开(公告)日：2007-12-27
申请号：PCT/US2007/071646
申请日：2007-06-20
申请人： AORTX, INC. , FORSTER, David, C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott
发明人： FORSTER, David, C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott
IPC分类号： A61F2/24
CPC分类号： A61F2/2433 , A61B17/22012 , A61B17/320016 , A61B17/320092 , A61B2017/00876 , A61B2017/22097 , A61B2017/22098 , A61F2/2427
摘要： Prosthetic valves implantation methods and systems, especially as related to preparing the native site of a native stenotic or incompetent aortic valve for receipt of a prosthetic replacement valve are described. The subject tools and associated site preparation techniques may be employed in percutaneous aortic valve replacement procedures.
摘要翻译：描述了假体瓣膜植入方法和系统，特别是与制备用于接受假体置换瓣膜的天然狭窄或无能的主动脉瓣的天然部位有关的。经皮主动脉瓣置换手术中可采用主题工具和相关部位制备技术。

3. 发明申请

WO2007149841A2 TORQUE SHAFT AND TORQUE DRIVE 审中-公开
标题翻译：扭矩轴和扭矩驱动
公开(公告)号：WO2007149841A2
公开(公告)日：2007-12-27
申请号：PCT/US2007/071535
申请日：2007-06-19
申请人： AORTX, INC. , FORSTER, David C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott , ROTH, Alex
发明人： FORSTER, David C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott , ROTH, Alex
IPC分类号： B60K17/24
CPC分类号： A61M25/0113 , A61F2/2427 , A61M25/0043 , A61M25/0138 , A61M25/0147 , F16C1/04 , F16C2226/78 , F16C2316/10 , Y10T403/70 , Y10T403/7045 , Y10T403/7073
摘要： Torque shafts and other related systems and methods are described herein. The torque shafts are both flexible and capable of transmitting torque. The torque shafts are useful for procedures that require torque and pushability to drive or deploy a device. The flexibility and pushability of the torque shafts enable them to curve along a tortuous path, and the torque transferring capability of the shafts enable them to transmit torque along the shaft.
摘要翻译：本文描述了扭矩轴和其它相关的系统和方法。扭矩轴既灵活又能够传递扭矩。扭矩轴对于要求扭矩和推动性来驱动或部署设备的过程非常有用。扭矩轴的灵活性和推力使其能够沿着曲折的路径弯曲，并且轴的转矩传递能力使得它们能够沿轴传递扭矩。

4. 发明申请

WO2008030946A1 PROSTHETIC HEART VALVES, SUPPORT STRUCTURES AND SYSTEMS AND METHODS FOR IMPLANTING THE SAME 审中-公开
标题翻译：前置心脏瓣膜，支撑结构和系统及其插入方法
公开(公告)号：WO2008030946A1
公开(公告)日：2008-03-13
申请号：PCT/US2007/077741
申请日：2007-09-06
申请人： AORTX, INC. , FORSTER, David, C. , BECKEY, Brian , HENEVELD, Scott , WALSH, Brandon
发明人： FORSTER, David, C. , BECKEY, Brian , HENEVELD, Scott , WALSH, Brandon
IPC分类号： A61F2/01
CPC分类号： A61F2/2418 , A61F2230/0058
摘要： The implantable heart valve can have an inverted configuration and can include a support structure and at least two valve leaflets. Preferably, when the valve is placed in proximity with an aortic valve implantation site of a subject and engaged with the implantation site, the valve leaflets are configured to deflect towards the aortic wall into a first position for resisting the flow of blood towards the left ventricle and configured to deflect away from a aortic wall into a second position for allowing the flow of blood from a left ventricle, with the support structure configured to remain static during leaflet deflection.
摘要翻译：可植入心脏瓣膜可以具有倒置构造并且可以包括支撑结构和至少两个瓣膜小叶。优选地，当阀被放置在受试者的主动脉瓣植入位置附近并与植入部位接合时，瓣膜小叶构造成朝向主动脉壁偏转到第一位置以抵抗朝向左心室的血液流动并且构造成偏离主动脉壁进入第二位置，以允许来自左心室的血液流动，其中所述支撑结构构造成在小叶偏转期间保持静止。

5. 发明申请

WO2007149933A2 PROSTHETIC VALVE IMPLANTATION SYSTEMS 审中-公开
标题翻译：前置植物植入系统
公开(公告)号：WO2007149933A2
公开(公告)日：2007-12-27
申请号：PCT/US2007/071689
申请日：2007-06-20
申请人： AORTX, INC. , FORSTER, David C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott
发明人： FORSTER, David C. , BECKEY, Brian , WALSH, Brandon , HENEVELD, Scott
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2220/0083 , A61F2250/0003 , A61F2250/006 , A61F2250/0069
摘要： Prosthetic valves implantation methods and systems, especially as related to fitting a prosthetic valve at the site of a native stenotic or incompetent valve are described. The subject devices, systems and associated dock deployment and implant docking techniques may be employed in percutaneous valve replacement procedures.
摘要翻译：描述了假体瓣膜植入方法和系统，特别是关于在天然狭窄或无能力瓣膜的部位安装人工瓣膜的方法和系统。可以在经皮瓣膜置换手术中使用主题装置，系统和相关的底座部署和植入物对接技术。

6. 发明申请

WO2007101160A3 METHODS AND DEVICES FOR DELIVERY OF PROSTHETIC HEART VALVES AND OTHER PROSTHETICS 审中-公开
公开(公告)号：WO2007101160A3
公开(公告)日：2007-09-07
申请号：PCT/US2007/062819
申请日：2007-02-26
申请人： AORTX, INC. , FORSTER, David C. , HENEVELD, Scott , WALSH, Brandon , BECKLEY, Brian
发明人： FORSTER, David C. , HENEVELD, Scott , WALSH, Brandon , BECKLEY, Brian
IPC分类号： A61F2/06
摘要： Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described.

7. 发明申请

WO2007101159A2 METHODS AND DEVICES FOR DELIVERY OF PROSTHETIC HEART VALVES AND OTHER PROSTHETICS 审中-公开
标题翻译：用于输送人造心脏瓣膜和其他假体的方法和设备
公开(公告)号：WO2007101159A2
公开(公告)日：2007-09-07
申请号：PCT/US2007/062818
申请日：2007-02-26
申请人： AORTX, INC. , FORSTER, David C. , HENEVELD, Scott , WALSH, Brandon , BECKLEY, Brian
发明人： FORSTER, David C. , HENEVELD, Scott , WALSH, Brandon , BECKLEY, Brian
CPC分类号： A61F2/2439 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2002/9522 , A61F2220/005 , A61F2220/0058 , A61F2230/0023 , A61F2250/0003
摘要： Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described.
摘要翻译：描述了假体瓣膜及其组成部件，人造瓣膜输送设备及其使用方法也如此。人造瓣膜特别适用于经皮主动脉瓣置换手术。输送装置特别适用于微创外科手术。优选的输送装置包括具有连接到其远端的展开机构的导管和连接到其近端的手柄机构。提供多个系绳以在展开期间选择性地约束阀。还描述了部分扩展人工瓣膜主动部署的一些机制。

8. 发明申请

WO2005084595A1 PROSTHETIC HEART VALVE DELIVERY SYSTEMS AND METHODS 审中-公开
标题翻译：先天性心脏瓣膜输送系统及方法
公开(公告)号：WO2005084595A1
公开(公告)日：2005-09-15
申请号：PCT/US2005/006189
申请日：2005-02-25
申请人： CARDIACMD, INC. , FORSTER, David C. , HENEVELD, Scott , WALSH, Brandon , GINN, Richard S.
发明人： FORSTER, David C. , HENEVELD, Scott , WALSH, Brandon , GINN, Richard S.
IPC分类号： A61F02/24
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0008 , A61F2220/0016 , A61F2220/0033 , A61F2220/005 , A61F2220/0091 , A61F2230/0013 , A61F2230/005 , A61F2230/0091 , A61F2250/001 , A61F2250/006 , A61F2250/0063
摘要： Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures.
摘要翻译：描述了假体瓣膜及其组成部分，以及假体瓣膜输送装置及其使用方法。人造瓣膜特别适用于经皮主动脉瓣置换手术。输送装置特别适用于微创外科手术。

9. 发明申请

WO2011081913A1 APPARATUS AND METHODS FOR LIMITING PRESSURE AND FLOW WITHIN A MEDICAL INJECTOR 审中-公开
标题翻译：用于限制医用注射器内的压力和流量的装置和方法
公开(公告)号：WO2011081913A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/060225
申请日：2010-12-14
申请人： NORDSON CORPORATION , KRUMME, John , HENEVELD, Scott
发明人： KRUMME, John , HENEVELD, Scott
IPC分类号： A61M5/168
CPC分类号： A61M5/24 , A61M5/20 , A61M5/3134 , A61M5/34 , A61M5/488 , A61M39/22 , A61M2005/2488 , A61M2005/2492 , A61M2005/3128 , A61M2205/14
摘要： A medical injector (200) includes a medicament container (210) including a main lumen (214) and a reduced-diameter protrusion (220), a needle assembly (230) coupled to the protrusion (220), and a flow control member (250). The medicament container (210) is configured to contain a medicament, such as, for example, a dermal filler. The flow control member (250) is disposed within the protrusion (220) of the medicament container (210), and includes a flow control lumen (254) configured to control a pressure or a flow of the medicament. Thus, the flow control member (250) reduces decoupling forces applied to the needle assembly (230) by the flow of medicament. Alternatively, the flow control member (250) may move from a first position allowing flow from the main lumen (214) to the needle assembly (230) to a second position blocking flow from the medicament container (210) when the needle assembly (230) decouples from the protrusion (220).
摘要翻译：医疗注射器（200）包括药物容器（210），其包括主腔（214）和缩径直径突起（220），联接到突起（220）的针组件（230）和流动控制构件 250）。药物容器（210）构造成容纳药物，例如皮肤填充剂。流量控制构件（250）设置在药物容器（210）的突出部（220）内，并且包括配置成控制药物的压力或流动的流动控制腔（254）。因此，流动控制构件（250）通过药物流减小施加到针组件（230）的去耦力。或者，流动控制构件（250）可以从第一位置移动，允许从主腔（214）到针组件（230）的流动到针组件（230）处阻止从药物容器（210）流动的第二位置）与突起（220）分离。

10. 发明申请

WO2013019370A1 DUAL INSUFFLATION AND WOUND CLOSURE DEVICES AND METHODS 审中-公开
标题翻译：双重消除和封闭装置和方法
公开(公告)号：WO2013019370A1
公开(公告)日：2013-02-07
申请号：PCT/US2012/046291
申请日：2012-07-11
申请人： SUTURE EASE, LLC , HENEVELD, Scott , AKYUZ, Ephraim
发明人： HENEVELD, Scott , AKYUZ, Ephraim
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0482 , A61B17/0485 , A61B2017/00637 , A61B2017/00663 , A61B2017/00867 , A61B2017/2911 , A61B2017/3484
摘要： A dual functioning instrument set, comprising a needle and guide, has not only the capabilities to enter and insufflate the abdominal cavity but also the ability of a suture passer to carry and retrieve suture for closure of the incision sites at the end of the procedure. The needle contains a deployable snare that is used to pass and retrieve suture. The guide is used to repeatedly locate the needle relative to the inner abdominal wall allowing for consistent placement of sutures. For insufflation purposes, obturator tips having different distal structures are provided for shielding the sharp needle tip after insertion through a body wall.
摘要翻译：包括针和引导件的双功能仪器组不仅具有进入和灌注腹腔的能力，而且还具有缝合路人携带和恢复缝合线以在手术结束时关闭切口部位的能力。针包含一个可部署的圈套，用于传递和检索缝合线。该引导件用于相对于内腹壁重复定位针，以允许缝合线一致放置。为了吹气目的，提供具有不同远端结构的闭孔器尖端，用于在穿过体壁插入之后屏蔽锋利的针尖。

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