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1. 发明申请

WO2012151501A3 APPARATUS FOR DETECTING TUMOR CELLS 审中-公开
标题翻译：检测肿瘤细胞的装置
公开(公告)号：WO2012151501A3
公开(公告)日：2013-04-25
申请号：PCT/US2012036551
申请日：2012-05-04
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD , YU CHRIS C , DU XUEDONG , YU HE
发明人： YU CHRIS C , DU XUEDONG , YU HE
IPC分类号： G01N33/574 , G01N27/26 , G01N27/72
CPC分类号： G01N33/574 , A61B5/07 , A61B5/14503 , A61B5/1451 , A61B5/14517 , A61B5/14528 , A61B5/14546 , A61B10/0041 , A61B2562/028 , A61B2562/12 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2200/0663 , B01L2200/0668 , B01L2300/0627 , B01L2300/0636 , B01L2300/0645 , B01L2300/0681 , B01L2300/0858 , B01L2300/0887 , B01L2300/123 , B01L2300/163 , B01L2400/0487 , C12Q1/68 , G01N1/34 , G01N1/4077 , G01N15/1056 , G01N15/1484 , G01N33/487 , G01N33/5091 , G01N33/54366 , G01N2001/4088 , G01N2015/0065 , G01N2015/1006 , G01N2015/1062 , G01N2015/1486
摘要： Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro¬ chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio-electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.
摘要翻译：其中，本发明提供了一种检测循环肿瘤细胞的装置，包括系统递送生物体和探测和检测装置，其中探测和检测装置包括第一微器件和支撑第一微器件的第一衬底，第一微型装置接触待检测的生物材料，并且能够在微观层面上测量电，磁，电磁，热，光，声，生物，化学，机电，电化学，电光学，电热，电化学机械，生物化学，生物机械，生物光学，生物热，生物物理，生物电机械，生物电化学，生物电光学，电热，生物机械光学，生物机械热学，生物热光学，生物电化学光学，生物机电光学，生物电热光学，生物电化学机械，物理或机械专业生物学或其组合。

2. 发明申请

WO2013019930A3 DECOMPOSABLE APPARATUS AND METHODS FOR FABRICATING SAME 审中-公开
标题翻译：可拆卸设备及其制造方法
公开(公告)号：WO2013019930A3
公开(公告)日：2013-08-15
申请号：PCT/US2012049287
申请日：2012-08-02
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD , YU CHRIS C , DU XUEDONG
发明人： YU CHRIS C , DU XUEDONG
IPC分类号： A61K47/42 , A61B17/00 , A61K47/48 , A61L27/14
CPC分类号： A61K9/0097 , A61M31/002 , A61M37/00 , A61M39/0208
摘要： The invention provides decomposing apparatus which comprises a fist sub-component and a first micro device comprising a decomposable material, wherein the sub-component comprises a drug, a medical kit, a micro-disease detection system, or an auto-navigation system. Also within the invention are methods for fabricating such apparatus.
摘要翻译：本发明提供分解装置，其包括第一子部件和包含可分解材料的第一微型装置，其中所述子部件包括药物，医疗试剂盒，微病症检测系统或自动导航系统。本发明也是制造这种装置的方法。

3. 发明申请

WO2012129299A3 MEDICAL INSTRUMENTS AND METHODS FOR FABRICATING SAME 审中-公开
标题翻译：医疗器械及其制造方法
公开(公告)号：WO2012129299A3
公开(公告)日：2013-02-14
申请号：PCT/US2012029931
申请日：2012-03-21
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD , YU CHRIS C , DU XUEDONG
发明人： YU CHRIS C , DU XUEDONG
IPC分类号： A61B17/00 , A61B17/14 , A61B17/16 , A61B17/32 , B21G1/00
CPC分类号： A61B17/32 , A61B17/3209 , A61B2017/00526 , A61M13/003 , A61M16/00 , A61M2205/0244 , A61M2207/00 , A61M2230/50 , Y10T29/49826 , Y10T29/49885
摘要： The present invention provides novel medical instruments and methods for fabricating them by using nano-technology processes.
摘要翻译：本发明提供了通过使用纳米技术工艺制造它们的新型医疗仪器和方法。

4. 发明申请

WO2012003348A3 APPARATUS FOR DISEASE DETECTION 审中-公开
标题翻译：疾病检测设备
公开(公告)号：WO2012003348A3
公开(公告)日：2013-01-03
申请号：PCT/US2011042637
申请日：2011-06-30
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD , YU CHRIS C , DU XUEDONG , YU HE
发明人： YU CHRIS C , DU XUEDONG , YU HE
IPC分类号： G01N33/53 , C12Q1/68 , G01N27/26 , G01N35/00
CPC分类号： G01N33/50 , A61B5/00 , A61B2560/0406 , B01L3/5027 , B01L3/502707 , B01L2200/0652 , B01L2200/0663 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2400/0415 , B01L2400/043 , C12Q1/68 , C12Q1/70 , G01N15/14 , G01N27/416 , G01N33/5005 , G01N33/68 , G01N35/1095 , Y10T436/143333
摘要： Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.
摘要翻译：其中，本发明提供了一种疾病检测装置，包括系统输送生物体和探测装置，其中探测和检测装置包括第一微器件和支撑第一微器件的第一基片，第一微器件接触待检测的生物材料，并且能够在微观层面测量生物材料的电，磁，电磁，热，光学，声学，生物学，化学，物理或机械性质。

5. 发明专利

CA2789682C METHOD OF FABRICATING MICRO-DEVICES 未知
公开(公告)号：CA2789682C
公开(公告)日：2020-03-24
申请号：CA2789682
申请日：2011-02-13
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD
发明人： YU CHRIS C
IPC分类号： B81C1/00 , A61B5/00 , A61B10/04 , G01N1/00
摘要： Methods for fabricating new types of micro-devices for biological and medical applications are disclosed. These novel methods employ microelectronics process technologies and novel process flows to fabricate micro-devices that have improved performance, flexibility and the ability for disease detection and treatment at microscopic levels. These micro-devices have reduced costs over the conventional methodologies and vehicles found in current medical treatment modalities. Micro-devices fabricated using the disclosed nano-technological techniques have significant improvements in many areas over the existing, conventional methods. Such. improvements include, but are not limited to reduced overall costs, early disease detection/diagnosis, targeted drug delivery, targeted disease treatment and reduced degree of invasiveness in treatment. Compared with existing, conventional approaches, the said inventive approach disclosed in this patent application is much more microscopic, sensitive, accurate, precise, flexible and effective. This novel approach is able to deliver a superior level of performance in medical treatments over the existing modalities.

6. 发明专利

AU2011218339B2 Methods of fabricating micro-devices 未知
公开(公告)号：AU2011218339B2
公开(公告)日：2015-11-26
申请号：AU2011218339
申请日：2011-02-13
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD
发明人： YU CHRIS C
IPC分类号： H01L21/00 , A61B5/00 , A61B10/04
摘要： Methods for fabricating new types of micro-devices for biological and medical applications are disclosed. These novel methods employ microelectronics process technologies and novel process flows to fabricate micro-devices that have improved performance, flexibility and the ability for disease detection and treatment at microscopic levels. These micro-devices have reduced costs over the conventional methodologies and vehicles found in current medical treatment modalities. Micro-devices fabricated using the disclosed nano-technological techniques have significant improvements in many areas over the existing, conventional methods. Such. improvements include, but are not limited to reduced overall costs, early disease detection/diagnosis, targeted drug delivery, targeted disease treatment and reduced degree of invasiveness in treatment. Compared with existing, conventional approaches, the said inventive approach disclosed in this patent application is much more microscopic, sensitive, accurate, precise, flexible and effective. This novel approach is able to deliver a superior level of performance in medical treatments over the existing modalities.

7. 发明专利

CA3073148A1 METHOD OF DRUG DELIVERY USING MICRO-DEVICES 未知
公开(公告)号：CA3073148A1
公开(公告)日：2011-01-13
申请号：CA3073148
申请日：2010-07-03
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD
发明人： YU CHRIS C , YU HE

8. 发明专利

CA2766766C MICRO-DEVICES FOR DRUG DELIVERY 未知
公开(公告)号：CA2766766C
公开(公告)日：2020-04-07
申请号：CA2766766
申请日：2010-07-03
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD
发明人： YU HE , YU CHRIS C
IPC分类号： A61K9/50 , A61K9/52
摘要： A drug delivery method is disclosed. A micro-carrier delivers an encapsulated drug directly to targeted sites without significant interactions with other components in the biological system. In one embodiment, a micro-carrier is first delivered to the general area for treatment. It then scans the area and selectively attaches itself to the cell site or organ location to be treated. Finally, the desired drug contained in the micro-earner is released to the attached site. In another embodiment, a micro-device is first used to process the general area to enhance differentiation in properties between cells and unhealthy cells. Drug is encapsulated in the micro-carrier to preferentially attach onto the targeted sites. Finally, drug is released from the micro-carrier onto the sites. Such microcarriers preferably contains multiple functions comprised of at least two of sensing, analyzing, logic processing, surface treatment, position detection, motion, injecting, delivering, cutting functions, removing functions, biodegradation and disintegration.

9. 发明专利

ZA201300435B APPARATUS FOR DISEASE DETECTION 未知
公开(公告)号：ZA201300435B
公开(公告)日：2013-09-25
申请号：ZA201300435
申请日：2013-01-16
申请人： ANPAC BIO-MEDICAL SCIENCE CO LTD
发明人： YU CHRIS C , YU HE , DU XUEDONG
IPC分类号： C12Q20060101 , G01N20060101
摘要： Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

10. 发明专利

AU2011218339A1 Methods of fabricating micro-devices 未知
公开(公告)号：AU2011218339A1
公开(公告)日：2012-09-13
申请号：AU2011218339
申请日：2011-02-13
申请人： ANPAC BIO MEDICAL SCIENCE CO LTD
发明人： YU CHRIS C
IPC分类号： H01L21/00 , A61B5/00 , A61B10/04
摘要： Methods for fabricating new types of micro-devices for biological and medical applications are disclosed. These novel methods employ microelectronics process technologies and novel process flows to fabricate micro-devices that have improved performance, flexibility and the ability for disease detection and treatment at microscopic levels. These micro-devices have reduced costs over the conventional methodologies and vehicles found in current medical treatment modalities. Micro-devices fabricated using the disclosed nano-technological techniques have significant improvements in many areas over the existing, conventional methods. Such. improvements include, but are not limited to reduced overall costs, early disease detection/diagnosis, targeted drug delivery, targeted disease treatment and reduced degree of invasiveness in treatment. Compared with existing, conventional approaches, the said inventive approach disclosed in this patent application is much more microscopic, sensitive, accurate, precise, flexible and effective. This novel approach is able to deliver a superior level of performance in medical treatments over the existing modalities.

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