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1. 发明申请

WO2010096380A1 TREATMENT OF A PELVIC CONDITION THROUGH INDIRECT ELECTRICAL STIMULATION 审中-公开
标题翻译：通过间接电刺激治疗器官状态
公开(公告)号：WO2010096380A1
公开(公告)日：2010-08-26
申请号：PCT/US2010/024287
申请日：2010-02-16
申请人： AMS RESEARCH CORPORATION , KOULLICK, Edouard, A. , WANG, Guangjian
发明人： KOULLICK, Edouard, A. , WANG, Guangjian
IPC分类号： A61N1/36 , A61B18/02 , A61B18/12
CPC分类号： A61N1/36007 , A61B18/02 , A61B18/12 , A61B18/1206 , A61B2018/00023 , A61B2018/0091 , A61B2018/00916
摘要： Embodiments of the invention are generally directed to a method of treating a pelvic condition of a patient through the indirect stimulation of a pelvic neuromuscular structure of the patient. In one embodiment of the method, an electrical stimulation signal is applied (138) to a first neuromuscular structure (134) of the patient. The electrical stimulation signal is communicated (144) through a neural pathway (140) to a second pelvic neuromuscular structure (142) of the patient. The second neuromuscular structure is stimulated (146) in response to the electrical stimulation signal communicated through the neural pathway. The pelvic condition is treated (148) in response to the stimulation of the second pelvic neuromuscular structure.
摘要翻译：本发明的实施方案一般涉及通过间接刺激患者的骨盆神经肌肉结构来治疗患者的盆腔状况的方法。在该方法的一个实施例中，对患者的第一神经肌肉结构（134）施加电刺激信号（138）。电刺激信号通过神经通路（140）与患者的第二盆腔神经肌肉结构（142）通信（144）。响应于通过神经通路传递的电刺激信号，第二神经肌肉结构受到刺激（146）。对第二盆腔神经肌肉结构的刺激响应治疗（148）骨盆状况。

2. 发明申请

WO2010107751A8 IMPLANTABLE DEVICE AND TISSUE ANCHOR 审中-公开
公开(公告)号：WO2010107751A8
公开(公告)日：2010-09-23
申请号：PCT/US2010/027419
申请日：2010-03-16
申请人： AMS RESEARCH CORPORATION , JAHNS, Scott, E. , WANG, Guangjian , MIRSCH, II, M., W. , LUND, Robert, E.
发明人： JAHNS, Scott, E. , WANG, Guangjian , MIRSCH, II, M., W. , LUND, Robert, E.
IPC分类号： A61N1/05
摘要： Embodiments of the invention are directed to an implantable device that includes a tissue anchor for securing a portion of the device to tissue of the patient. Embodiments of the implantable device include an electrode lead and a pelvic treatment apparatus. One embodiment of the electrode lead (104) comprises a lead body (110), an electrode (111) attached to a distal end (114) of the lead body and a tissue anchor (120). The electrode comprises a plurality of stimulation elements (112) formed of an electrically conductive material, and at least one insulative element (116) formed of an electrically non-conductive material. The stimulation elements and the at least one insulative element are joined together to form a stacked column (140) of alternating stimulation and insulative elements. The electrode lead also comprises a plurality of electrically conductive wires (118) each extending through the lead body and coupled to one of the stimulation elements. The tissue anchor is configured to facilitate anchoring the electrode to tissue (240) of the patient.

3. 发明申请

WO2011143572A8 IMPLANTABLE MECHANICAL SUPPORT 审中-公开
公开(公告)号：WO2011143572A8
公开(公告)日：2011-11-17
申请号：PCT/US2011/036455
申请日：2011-05-13
申请人： AMS RESEARCH CORPORATION , WATSCHKE, Brian, P. , WANG, Guangjian
发明人： WATSCHKE, Brian, P. , WANG, Guangjian
IPC分类号： A61N1/36 , A61N1/05 , A61F2/00
摘要： Embodiments of the invention are generally directed to a mechanical support (102) of a pelvic treatment apparatus (100) that is configured for implantation in the pelvic region of a patient for the purpose of treating a pelvic condition of the patient, such as urinary incontinence, fecal incontinence, sexual dysfunction, or other pelvic related condition. In some embodiments, the implantable mechanical support comprises a section of mesh (104) having a longitudinal axis (106) and at least one radiopaque mark (114) covering a subsection of the section of mesh. Additional embodiments are directed to methods of attaching an electrode lead (122) or an electrical lead (180) to the mechanical support subsequent to the implantation of the mechanical support using the radiopaque mark.

4. 发明申请

WO2011100162A1 SYSTEM FOR TREATING A PELVIC CONDITION OF A PATIENT 审中-公开
标题翻译：用于治疗患者的器官状况的系统
公开(公告)号：WO2011100162A1
公开(公告)日：2011-08-18
申请号：PCT/US2011/023677
申请日：2011-02-04
申请人： AMS RESEARCH CORPORATION , RISSMANN, William, J. , WANG, Guangjian , WATSCHKE, Brian, P.
发明人： RISSMANN, William, J. , WANG, Guangjian , WATSCHKE, Brian, P.
IPC分类号： A61N1/36
CPC分类号： A61N1/36007
摘要： A system (100) for treating a pelvic condition of a patient includes a plurality of electrodes (104), a memory (such as 130, 132 or 140) a plurality of predefined unique stimulation programs (128) stored in the memory, and an implantable controller (103). Each of the stimulation programs defines a stimulation signal and an identification of one or more of the electrodes to which the stimulation signal is to be applied. The implantable controller is electrically coupled to the plurality of electrodes and is configured to execute a selected stimulation program from the memory to apply a stimulation signal to one or more of the electrodes in accordance with the selected stimulation program.
摘要翻译：用于治疗患者的盆腔状态的系统（100）包括多个电极（104），存储器（诸如130,132或140）存储在存储器中的多个预定义的独特刺激程序（128），以及可植入控制器（103）。每个刺激程序定义刺激信号和要施加刺激信号的一个或多个电极的识别。可植入控制器电耦合到多个电极，并且被配置为执行来自存储器的所选择的刺激程序，以根据所选择的刺激程序向一个或多个电极施加刺激信号。

5. 发明申请

WO2014055521A1 CONDUCTIVE AND DEGRADABLE IMPLANT FOR PELVIC TISSUE TREATMENT 审中-公开
标题翻译：用于皮肤组织治疗的导电和可降解植入物
公开(公告)号：WO2014055521A1
公开(公告)日：2014-04-10
申请号：PCT/US2013/062870
申请日：2013-10-01
申请人： AMS RESEARCH CORPORATION , WANG, Guangjian
发明人： WANG, Guangjian
IPC分类号： A61F2/00
CPC分类号： A61F2/0063 , A61F2/0045 , A61F2210/0004 , A61F2250/0001 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/148 , A61N1/0514 , A61N1/36007 , C08L67/04 , C08L79/02 , C08L65/00
摘要： Described is a pelvic implant comprising a biodegradable conductive mesh. The mesh can include biodegradable and electrically conductive polymer, and can be stimulated with a current to generate an electric field to promote an improved tissue response following placement of the implant. The invention also describes methods and systems including the pelvic implant comprising a biodegradable conductive mesh for the treatment of pelvic floor conditions. Implants of the invention provide benefits relating to improved tissue integration into the mesh, resulting in pelvic tissue reconstruction. Tissue reconstruction and elimination of the mesh materials can lead to a better clinical outcome for the patient.
摘要翻译：描述了包括可生物降解的导电网的骨盆植入物。网可以包括可生物降解和导电的聚合物，并且可以用电流刺激以产生电场，以在植入物放置之后促进改善的组织反应。本发明还描述了包括骨盆植入物的方法和系统，其包括用于治疗盆底病症的可生物降解的导电网。本发明的植入物提供与改进的组织整合到网中有关的益处，导致骨盆组织重建。组织重建和消除网状材料可以为患者带来更好的临床疗效。

6. 发明申请

WO2014062767A1 SURGICAL LASER SYSTEM AND LASER FIBER 审中-公开
标题翻译：外科激光系统和激光光纤
公开(公告)号：WO2014062767A1
公开(公告)日：2014-04-24
申请号：PCT/US2013/065181
申请日：2013-10-16
申请人： AMS RESEARCH CORPORATION
发明人： HASENBERG, Thomas, Charles , PENG, Steven, Yihlih , WATSCHKE, Brian, P. , EVANS, Douglas, L. , WANG, Guangjian , XUAN, Rongwei, Jason , CHIA, Wen-jui, Ray
IPC分类号： A61B18/22
CPC分类号： A61B18/22 , A61B18/26 , A61B2018/00511 , A61B2018/00517 , A61B2018/00577 , A61B2018/00589 , A61B2018/00601 , A61B2018/00625 , A61B2018/00898 , A61B2018/207 , A61B2018/2272
摘要： An optical device including an optical fiber having a longitudinal axis and an optical fiber core with a distal end having a distal terminating end configured to discharge a first laser energy in a first direction and a second laser energy in a second direction. The optical device also includes a fiber cap having an interior cavity and an opening to the interior cavity, where the distal end of the optical fiber core is received within the interior cavity through the opening. A cladding is included on the distal end of the optical fiber core between the optical fiber core and the fiber cap.
摘要翻译：一种光学装置，其包括具有纵向轴线的光纤和具有远端的光纤芯，所述远端具有构造成沿第一方向排出第一激光能量并且在第二方向上排出第二激光能量。光学装置还包括具有内部空腔和通向内部空腔的开口的光纤盖，其中光纤芯的远端通过开口被容纳在内部空腔内。在光纤芯和纤维帽之间的光纤芯的远端包括包层。

7. 发明申请

WO2013130529A1 PERINEUM OVERLAY DEVICE 审中-公开
公开(公告)号：WO2013130529A1
公开(公告)日：2013-09-06
申请号：PCT/US2013/027914
申请日：2013-02-27
申请人： AMS RESEARCH CORPORATION
发明人： WATSCHKE, Brian, P. , WANG, Guangjian
IPC分类号： A61B19/08
CPC分类号： A61B19/087 , A61B17/0482 , A61B17/3403 , A61B46/30 , A61B2017/00805 , A61B2017/3407 , A61B2017/3411 , A61B2046/205 , A61B2090/034 , A61B2090/0807 , A61B2090/3937
摘要： A perineum overlay device for locating anatomical features within the perineum of a patient and/or needle insertion sites for targeting anatomical features within the perineum of a patient includes a section of flexible material and a plurality of markings printed on a first side of the section of the material. The section of flexible material is configured to conform and cover a portion of the perineum of a patient. The plurality of markings are each configured to identify a location of an anatomical feature within the perineum and/or a needle insertion site corresponding to a targeted anatomical feature within the perineum, when the section is positioned over the perineum of a patient.
摘要翻译：用于定位患者会阴内的解剖特征的会阴覆盖装置和/或用于靶向患者会阴内的解剖特征的针插入位置包括柔性材料的一部分和印刷在所述部分的第一侧上的多个标记材料。柔性材料的部分构造成使患者的会阴部分符合并覆盖。多个标记各自被配置为当该部分位于患者的会阴上时，识别会阴内的解剖特征的位置和/或对应于会阴内的目标解剖特征的针插入位置。

8. 发明申请

WO2014062219A1 LASER ABLATION WITH ELECTROMAGNETIC ENERGY FEEDBACK 审中-公开
标题翻译：激光雷达与电磁能量反馈
公开(公告)号：WO2014062219A1
公开(公告)日：2014-04-24
申请号：PCT/US2013/030138
申请日：2013-03-11
申请人： AMS RESEARCH CORPORATION
发明人： XUAN, Rongwei, Jason , WATSCHKE, Brian, P. , EVANS, Douglas, L. , WANG, Guangjian , CHIA, Wen-Jui, Ray , BROWN, Nathan , HASENBERG, Thomas, C. , ZHANG, Jian James , KANG, Hyun, Wook
IPC分类号： A61B18/18
CPC分类号： A61B18/22 , A61B2018/00511 , A61B2018/00517 , A61B2018/00547 , A61B2018/00577 , A61B2018/00589 , A61B2018/00601 , A61B2018/00625 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/00708 , A61B2018/00732 , A61B2018/00785 , A61B2018/00898 , A61B2018/00904 , A61B2018/2272
摘要： Embodiments of a surgical laser system comprise a laser source (102), a laser fiber (104), a photodetector (106) and a controller (108). The laser source is configured to generate laser energy (1 10). The laser fiber is optically coupled to the laser source and is configured to discharge the laser energy generated by the laser source. The photodetector is configured to generate an output signal (1 12) that is indicative of an intensity level of electromagnetic energy feedback ( 114) that is produced in response to the discharge of the laser energy. The controller is configured to control the laser source based on the output signal.
摘要翻译：外科激光系统的实施例包括激光源（102），激光光纤（104），光电检测器（106）和控制器（108）。激光源被配置为产生激光能量（110）。激光光纤光学耦合到激光源并且被配置为放电由激光源产生的激光能量。光电检测器被配置为产生指示响应于激光能量的放电而产生的电磁能量反馈（114）的强度水平的输出信号（112）。控制器被配置为基于输出信号来控制激光源。

9. 发明授权

EP2974769B1 IMPLANTABLE DEVICE AND TISSUE ANCHOR 有权
标题翻译：可植入装置和组织锚
公开(公告)号：EP2974769B1
公开(公告)日：2017-09-27
申请号：EP15176464.4
申请日：2010-03-16
申请人： AMS Research Corporation
发明人： LUND, Robert E. , WANG, Guangjian
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/36007

10. 发明公开

EP2974769A2 IMPLANTABLE DEVICE AND TISSUE ANCHOR 有权
公开(公告)号：EP2974769A2
公开(公告)日：2016-01-20
申请号：EP15176464.4
申请日：2010-03-16
申请人： AMS Research Corporation
发明人： LUND, Robert E. , WANG, Guangjian
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/36007
摘要： The invention provides an implantable electrode lead for facilitating electrical stimulation of tissue of a patient, the electrode lead comprising a lead body having a distal end; an electrode attached to the distal end of the lead body, the electrode comprising a plurality of stimulation elements formed of an electrically conductive material; and at least one insulative element formed of an electrically non-conductive material; wherein the stimulation elements and the at least one insulative element are joined together to form a stacked column of alternating stimulation and insulative elements; a plurality of electrically conductive wires extending through the lead body, each wire coupled to one of the stimulation elements; and a tissue anchor configured to facilitate anchoring the electrode to tissue of the patient, wherein each of the stimulation elements comprises a body having first and second ends; and each of the at least one insulative elements comprises a body having first and second ends that are respectively configured to interconnect with the second and first ends of the body of one of the stimulation elements.

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