专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2006044527A1 IMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS 审中-公开
标题翻译：咪唑衍生物作为VANILLOID受体配体
公开(公告)号：WO2006044527A1
公开(公告)日：2006-04-27
申请号：PCT/US2005/036800
申请日：2005-10-14
申请人： AMGEN INC.
发明人： GORE, Vijay Keshav , MA, Vu Van , NORMAN, Mark H. , OGNYANOV, Vassil I. , XI, Ning
IPC分类号： C07D401/12 , C07D233/88 , A61K31/4168 , A61P29/00
CPC分类号： C07D233/64 , C07D401/12
摘要： Therapeutic benzimidazoles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译：治疗性苯并咪唑和含有它们的组合物，用于治疗急性，炎性和神经性疼痛，牙痛，一般头痛，偏头痛，丛集性头痛，混合血管和非血管综合征，紧张性头痛，一般炎症，关节炎，风湿性疾病，骨关节炎，炎症性肠病，炎症性眼病，炎症性或不稳定性膀胱病，银屑病，皮肤炎症成分炎症，慢性炎性病症，炎性疼痛及相关的痛觉过敏和异常性疼痛，神经性疼痛及相关的痛觉过敏和异常性疼痛，糖尿病性神经病疼痛，灼痛，交感神经痛维持疼痛，输血综合征，哮喘，上皮组织损伤或功能障碍，单纯疱疹，呼吸道，泌尿生殖道，胃肠道或血管区内脏运动紊乱，伤口，烧伤，过敏性皮肤反应，瘙痒，白癜风，一般胃肠道疾病，胃溃疡十二指肠溃疡，腹泻，坏死因子诱导的胃损伤，毛发生长，血管舒缩或过敏性鼻炎，支气管疾病或膀胱疾病。

2. 发明申请

WO2005073193A1 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS 审中-公开
标题翻译： VANILLOID受体配体及其在治疗中的应用
公开(公告)号：WO2005073193A1
公开(公告)日：2005-08-11
申请号：PCT/US2005/002012
申请日：2005-01-21
申请人： AMGEN INC.
发明人： NCUBE, Mqhele Vellah , NORMAN, Mark H. , OGNYANOV, Vassil I. , PETTUS, Liping H.
IPC分类号： C07D213/02
CPC分类号： C07D213/26 , C07D213/61 , C07D213/73 , C07D213/75 , C07D213/89 , C07D401/12
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译：具有一般结构和含有它们的组合物的化合物，用于治疗急性，炎性和神经性疼痛，牙痛，一般头痛，偏头痛，丛集性头痛，混合血管和非血管综合征，紧张性头痛，一般炎症，关节炎，风湿性疾病，骨关节炎，炎症性肠病，炎症性眼病，炎症性或不稳定性膀胱病，银屑病，皮肤炎症成分炎症，慢性炎性病症，炎性疼痛及相关的痛觉过敏和异常性疼痛，神经性疼痛及相关的痛觉过敏和异常性疼痛，糖尿病性神经病疼痛，咳嗽痛，交感神经痛，交感综合症，哮喘，上皮组织损伤或功能障碍，单纯疱疹，呼吸系统内脏运动紊乱，泌尿生殖道，胃肠道或血管区，伤口，烧伤，过敏性皮肤反应，瘙痒，白癜风， G 腹部溃疡，十二指肠溃疡，腹泻，坏死因子诱导的胃损伤，毛发生长，血管舒缩或过敏性鼻炎，支气管疾病或膀胱疾病。

3. 发明申请

WO2006047492A2 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS 审中-公开
标题翻译： VANILLOID受体配体及其在治疗中的应用
公开(公告)号：WO2006047492A2
公开(公告)日：2006-05-04
申请号：PCT/US2005/038327
申请日：2005-10-21
申请人： AMGEN INC.
发明人： NORMAN, Mark H. , OGNYANOV, Vassil I. , RZASA, Robert M.
IPC分类号： C07D405/04 , C07D403/04 , A61K31/506 , A61P29/00
CPC分类号： C07D401/04 , C07D403/04 , C07D405/04
摘要： Substituted nitrogen-containing heterocycles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译：取代的含氮杂环和含有它们的组合物，用于治疗急性，炎性和神经性疼痛，牙痛，一般头痛，偏头痛，丛集性头痛，混合血管和非血管性综合征，紧张性头痛，一般炎症，关节炎，风湿性疾病，骨关节炎，炎症性肠病，炎症性眼病，炎症性或不稳定性膀胱病，银屑病，皮肤炎症成分炎症，慢性炎性病症，炎性疼痛及相关的痛觉过敏和异常性疼痛，神经性疼痛及相关的痛觉过敏和异常性疼痛，糖尿病性神经病疼痛，咳嗽痛，交感神经痛，交感综合征，哮喘，上皮组织损伤或功能障碍，单纯疱疹，呼吸道内脏运动紊乱，泌尿生殖道，胃肠道或血管区，伤口，烧伤，过敏性皮肤反应，瘙痒，白癜风，一般胃肠道紊乱胃溃疡，十二指肠溃疡，腹泻，坏死因子诱导的胃损伤，毛发生长，血管舒缩或过敏性鼻炎，支气管疾病或膀胱疾病。

4. 发明申请

WO2006078907A1 2-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS 审中-公开
标题翻译： 2-取代的苯并咪唑衍生物作为VANILLOID受体配体及其在治疗中的用途
公开(公告)号：WO2006078907A1
公开(公告)日：2006-07-27
申请号：PCT/US2006/002045
申请日：2006-01-20
申请人： AMGEN INC.
发明人： NORMAN, Mark H. , OGNYANOV, Vassil I. , WANG, Xianghong
IPC分类号： C07D401/12 , C07D235/30 , C07D235/26 , A61K31/4184 , A61K31/4709 , A61P29/00
CPC分类号： C07D235/26 , C07D235/30 , C07D401/12
摘要： Substituted benzimidazoles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译：取代的苯并咪唑和含有它们的组合物，用于治疗急性，炎性和神经性疼痛，牙痛，一般头痛，偏头痛，丛集性头痛，混合血管和非血管性综合征，紧张性头痛，一般炎症，关节炎，风湿性疾病，骨关节炎，炎症性肠病，炎症性眼病，炎症性或不稳定性膀胱病，银屑病，皮肤炎症成分炎症，慢性炎性病症，炎性疼痛及相关的痛觉过敏和异常性疼痛，神经性疼痛及相关的痛觉过敏和异常性疼痛，糖尿病性神经病疼痛，灼痛，交感神经痛维持疼痛，输血综合征，哮喘，上皮组织损伤或功能障碍，单纯疱疹，呼吸道，泌尿生殖道，胃肠道或血管区内脏运动紊乱，伤口，烧伤，过敏性皮肤反应，瘙痒，白癜风，一般胃肠道疾病，胃溃疡十二指肠溃疡，腹泻，坏死因子诱导的胃损伤，毛发生长，血管舒缩或过敏性鼻炎，支气管疾病或膀胱疾病。

5. 发明申请

WO2005070929A1 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS 审中-公开
标题翻译： VANILLOID受体配体及其在治疗中的应用
公开(公告)号：WO2005070929A1
公开(公告)日：2005-08-04
申请号：PCT/US2005/002057
申请日：2005-01-21
申请人： AMGEN INC.
发明人： NORMAN, Mark H. , OGNYANOV, Vassil I. , PETTUS, Liping H.
IPC分类号： C07D471/04
CPC分类号： C07D401/04 , C07D417/12 , C07D471/04
摘要： Compounds having the general structure formula (I) and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
摘要翻译：具有通式结构式（I）的化合物和含有它们的组合物，用于治疗急性，炎性和神经性疼痛，牙痛，一般头痛，偏头痛，丛集性头痛，混合血管和非血管性综合征，紧张性头痛，一般炎症，关节炎，风湿性疾病，骨关节炎，炎症性肠病，炎症性眼病，炎性或不稳定型膀胱病，牛皮癣，皮肤炎症成分投诉，慢性炎性病症，炎性疼痛及相关的痛觉过敏和异常性疼痛，神经性疼痛及相关的痛觉过敏和异常性疼痛，糖尿病性神经病疼痛，咳嗽痛，交感神经保持疼痛，交感综合征，哮喘，上皮组织损伤或功能障碍，单纯疱疹，呼吸道内脏运动紊乱，泌尿生殖道，胃肠道或血管区域，伤口，烧伤，过敏性皮肤反应，瘙痒症，白癜风，一般胃肠道疾病，胃溃疡，十二指肠溃疡，腹泻，坏死因子诱导的胃损伤，毛发生长，血管舒缩或过敏性鼻炎，支气管疾病或膀胱疾病。

6. 发明公开

EP1713807A1 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS 审中-公开
标题翻译： VANILLOIDREZEPTORLIGANDEN和它们在疗程组合
公开(公告)号：EP1713807A1
公开(公告)日：2006-10-25
申请号：EP05722499.0
申请日：2005-01-21
申请人： AMGEN INC.
发明人： NORMAN, Mark H. , OGNYANOV, Vassil I. , PETTUS, Liping H.
IPC分类号： C07D471/04 , C07D401/04 , C07D417/12 , A61K31/517 , A61K31/519 , A61K31/428
CPC分类号： C07D401/04 , C07D417/12 , C07D471/04
摘要： Compounds having the general structure formula (I) and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

7. 发明公开

EP1802605A1 IMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS 审中-公开
标题翻译：咪唑衍生物作为香草素受体的配体
公开(公告)号：EP1802605A1
公开(公告)日：2007-07-04
申请号：EP05810591.7
申请日：2005-10-14
申请人： Amgen, Inc
发明人： GORE, Vijay Keshav , MA, Vu Van , NORMAN, Mark H. , OGNYANOV, Vassil I. , XI, Ning
IPC分类号： C07D401/12 , C07D233/88 , A61K31/4168 , A61P29/00
CPC分类号： C07D233/64 , C07D401/12
摘要： Therapeutic benzimidazoles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

8. 发明授权

EP1542692B1 AMINOPYRIMIDINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN 有权
标题翻译： FOR USE AS辣椒素受体配体氨基嘧啶衍生物疼痛的治疗
公开(公告)号：EP1542692B1
公开(公告)日：2011-01-05
申请号：EP03755509.1
申请日：2003-05-20
申请人： AMGEN INC.
发明人： DOHERTY, Elizabeth, M. , ZHU, Jiawang , STEC, Markian , NORMAN, Mark, H. , FOTSCH, Christopher, H. , CHEN, Ning , CHAKRABARTI, Partha, P. , OGNYANOV, Vassil I. , WANG, Hui-Ling , WANG, Xianghong , ARASASINGHAM, Premilla , PETTUS, Liping.H
IPC分类号： A61K31/501 , A61K31/506 , A61P25/00 , C07D417/12 , C07D405/12 , C07D403/12 , C07D401/12 , C07D239/42 , C07D471/04 , C07D417/14
CPC分类号： C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

9. 发明公开

EP1807418A2 SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLES AS VANILLOID RECEPTOR LIGANDS AND THEIR USES AS MEDICAMENT 审中-公开
标题翻译：取代的含氮AS VANILLOIDREZEPTORLIGANDEN杂环及其作为药物
公开(公告)号：EP1807418A2
公开(公告)日：2007-07-18
申请号：EP05817010.1
申请日：2005-10-21
申请人： Amgen, Inc
发明人： NORMAN, Mark H. , OGNYANOV, Vassil I. , RZASA, Robert M.
IPC分类号： C07D405/04 , C07D403/04 , A61K31/506 , A61P29/00
CPC分类号： C07D401/04 , C07D403/04 , C07D405/04
摘要： Substituted nitrogen-containing heterocycles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

10. 发明公开

EP1542692A1 AMINO-PYRIDINE, -PYRIDINE AND PYRIDAZINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN 有权
标题翻译： FOR USE AS辣椒素受体配体氨基嘧啶衍生物疼痛的治疗
公开(公告)号：EP1542692A1
公开(公告)日：2005-06-22
申请号：EP03755509.1
申请日：2003-05-20
申请人： Amgen Inc.
发明人： DOHERTY, Elizabeth, M. , ZHU, Jiawang , STEC, Markian , NORMAN, Mark, H. , FOTSCH, Christopher, H. , CHEN, Ning , CHAKRABARTI, Partha, P. , OGNYANOV, Vassil I. , WANG, Hui-Ling , WANG, Xianghong , ARASASINGHAM, Premilla , PETTUS, Liping.H
IPC分类号： A61K31/501 , A61K31/506 , A61P25/00 , C07D417/12 , C07D405/12 , C07D403/12 , C07D401/12 , C07D239/42 , C07D471/04 , C07D417/14
CPC分类号： C07D231/40 , C07D209/08 , C07D209/12 , C07D209/42 , C07D209/48 , C07D213/26 , C07D213/643 , C07D213/74 , C07D213/75 , C07D215/227 , C07D215/38 , C07D217/04 , C07D231/56 , C07D233/38 , C07D237/20 , C07D239/42 , C07D239/90 , C07D241/42 , C07D263/56 , C07D265/36 , C07D277/62 , C07D277/82 , C07D307/79 , C07D319/20 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D407/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04
摘要： Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式