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1. 发明申请

WO2009087675A2 NOVEL COATED EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS OF LEVETIRACETAM 审中-公开
标题翻译：新型涂层延伸释放出的药物组合物
公开(公告)号：WO2009087675A2
公开(公告)日：2009-07-16
申请号：PCT/IN2008/000851
申请日：2008-12-22
申请人： ALEMBIC LIMITED , KSHIRSAGAR, Rajesh , RAO, Ashwin , KATHIRIYA, Atul
发明人： KSHIRSAGAR, Rajesh , RAO, Ashwin , KATHIRIYA, Atul
IPC分类号： A61K9/28 , A61K31/4015
CPC分类号： A61K9/2866 , A61K31/4015
摘要： An extended release pharmaceutical composition comprising levetiracetam. A coated extended release pharmaceutical composition comprising levetiracetam wherein the core is coated with a rate controlling composition.
摘要翻译：包含左乙拉西坦的延长释放药物组合物。包含左乙拉西坦的涂覆的延长释放药物组合物，其中核心被速率控制组合物包被。

2. 发明申请

WO2008062446A2 AN EXTENDED RELEASE COMPOSITION OF LEVETIRACETAM, WHICH EXHIBITS NO ADVERSE FOOD EFFECT 审中-公开
标题翻译：没有不良副作用的扩展释放组合物
公开(公告)号：WO2008062446A2
公开(公告)日：2008-05-29
申请号：PCT/IN2007/000420
申请日：2007-09-14
申请人： ALEMBIC LIMITED , KSHIRSAGAR, Rajesh , RAO, Ashwin , MALAVIYA, Nilesh , JINTURKAR, Kaustubh
发明人： KSHIRSAGAR, Rajesh , RAO, Ashwin , MALAVIYA, Nilesh , JINTURKAR, Kaustubh
CPC分类号： A61K9/2054 , A61K9/2013 , A61K9/2027 , A61K9/2866 , A61K31/4015 , C07D207/27
摘要： The present invention relates to extended release pharmaceutical compositions of Levetiracetam, which exhibits no adverse food effect, and processes for preparing the same. The extended release tablet of Levetiracetam is with a core comprising of Levetiracetam and water dispersible rate controlling polymer, and the tablet core is optionally functional coated comprising a combination of water non-dispersible and/or water dispersible polymer. It provides extended therapeutically effective plasma levels over a twenty four hour period with diminished incidences of neuropsychiatric adverse events by eliminating the troughs and peaks of drug concentration in a patient's blood plasma.
摘要翻译：本发明涉及不显示不良食物作用的左乙拉西坦的延长释放药物组合物及其制备方法。左乙拉西坦的延长释放片剂具有包含左乙拉西坦和水分散速率控制聚合物的核心，并且片芯任选功能性包衣，包含水不分散性和/或水分散性聚合物的组合。它通过消除患者血浆中药物浓度的波谷和峰值，在24小时内提供延长的治疗有效血浆水平，减少神经精神不良事件的发生率。

3. 发明申请

WO2008068778A3 EXTENDED RELEASE PHARMACEUTICAL COMPOSITION OF PRAMIPEXOLE 审中-公开
公开(公告)号：WO2008068778A3
公开(公告)日：2008-06-12
申请号：PCT/IN2007/000586
申请日：2007-12-05
申请人： ALEMBIC LIMITED , KSHIRSAGAR, Rajesh , RAO, Ashwin , MALAVIYA, Nilesh
发明人： KSHIRSAGAR, Rajesh , RAO, Ashwin , MALAVIYA, Nilesh
IPC分类号： A61K9/20 , A61K9/28
摘要： An extended release pharmaceutical composition comprising pramipexole having an extended release profile such that not less than 25% of the total amount of pramipexole or a pharmaceutically acceptable salt thereof in the composition is released within one hour no, significant release of the drug takes place over the subsequent one hour and not less than 80% of the total amount of pramipexole or a pharmaceutically acceptable salt thereof in the composition is released over a period of about 24 hours.

4. 发明申请

WO2011036421A1 REVETEMENTS PHOTOVOLTAÏQUES ORGANIQUES DE MORPHOLOGIE CONTRÔLEE 审中-公开
标题翻译：具有控制形态的有机光伏涂料
公开(公告)号：WO2011036421A1
公开(公告)日：2011-03-31
申请号：PCT/FR2010/052014
申请日：2010-09-24
申请人： RHODIA OPERATIONS , QI, Ling , PAVAGEAU, Bertrand , RAO, Ashwin
发明人： QI, Ling , PAVAGEAU, Bertrand , RAO, Ashwin
IPC分类号： H01L51/42 , H01L51/00
CPC分类号： H01L51/0007 , B82Y10/00 , H01L51/0026 , H01L51/0036 , H01L51/0037 , H01L51/0049 , H01L51/4253 , H01L2251/308 , Y02E10/549
摘要： La présente invention concerne un procédé permettant de réaliser un revêtement à base de deux composés organiques semi-conducteur C P et C N , respectivement de type P et de type N, C N étant immiscible au composé C P dans le revêtement réalisé, et où : (A) on dépose sur la surface du support une solution comprenant les composés C P et C N dans un milieu solvant S capable de solvater les composés C P et C N sans réagir chimiquement avec ceux-ci, ledit solvant S étant constitué par un mélange de : une première fraction constituée d'un solvant ou mélange de solvants S1 capable de solvater les deux composés C P ou C N ; et une seconde fraction, miscible à la première fraction, constituée d'un solvant ou mélange de solvants S2 qui a un point d'ébullition supérieur à celui du solvant ou mélange de solvants S1 et qui est capable de solvater sélectivement un des composés C P ou C N mais non l'autre; et (B) on élimine par évaporation le solvant S présent dans le dépôt ainsi réalisé.
摘要翻译：本发明涉及一种制备包含两种有机半导体化合物的涂层的方法，所述两种有机半导体化合物分别为P型和N型，CN在制备的涂层中与化合物CP不混溶。本发明包括以下步骤：（A）溶液沉积在载体的表面上，其中含有化合物CP和CN的溶剂介质S能溶剂化合物CP和CN而不与其化学反应，所述溶剂S由（i）由溶剂形成的第一级分或能够溶解两种化合物CP或CN的溶剂S1的混合物和（ii）与溶剂或溶剂混合物形成的第一级分混溶的第二级分 S2沸点高于溶剂或溶剂混合物S1的沸点，其能够选择性地溶剂化化合物CP或CN而不是另一种; 和（B）通过蒸发消除由此产生的沉积物中的溶剂S.

5. 发明申请

WO2007107605A3 A PROCESS FOR THE TREATMENT OF A HYDROPHOBIC SURFACE BY AN AQUEOUS PHASE 审中-公开
公开(公告)号：WO2007107605A3
公开(公告)日：2007-09-27
申请号：PCT/EP2007/052774
申请日：2007-03-22
申请人： RHODIA RECHERCHES ET TECHNOLOGIES , CASTAING, Jean-Christophe , RAO, Ashwin
发明人： CASTAING, Jean-Christophe , RAO, Ashwin
IPC分类号： C09D5/02 , C09D7/12
摘要： The invention relates to process for the treatment of a hydrophobic surface by a liquid film comprising an aqueous phase comprising the coating of said surface by the liquid whose aqueous phase comprises an effective amount of surface properties modifying agent and an active agent.

6. 发明申请

WO2009061435A1 ARTICLES HAVING AN INTERFACE BETWEEN A POLYMER SURFACE AND A MODIFIED GLASS SURFACE 审中-公开
标题翻译：在聚合物表面和改性玻璃表面之间具有界面的文章
公开(公告)号：WO2009061435A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/012522
申请日：2008-11-06
申请人： RHODIA INC. , RAO, Ashwin , TRIVEDI, Satyen , CASTAING, Jean-christophe , RUIZ, Jose , AYMES, Charlie , GRASSET, Amelie
发明人： RAO, Ashwin , TRIVEDI, Satyen , CASTAING, Jean-christophe , RUIZ, Jose , AYMES, Charlie , GRASSET, Amelie
IPC分类号： B05D1/36
CPC分类号： C03C17/42 , C03C25/465 , C03C2217/42 , Y10T428/2933 , Y10T428/315
摘要： An article includes (a) a glass substrate having a modified surface that comprises a glass surface and a layer of nanoscale inorganic oxide particles disposed in contact with and bound to at least a portion of the glass surface, and (b) a polymer layer disposed in contact with and bound to the modified glass surface. A method for improving the hydrolytic stability of an interface of a glass surface and a polymer surface, includes the step of, prior to forming the interface of the glass surface and the polymer surface, treating at least a portion of the glass surface with nanoscale inorganic oxide particles to modify the glass surface by depositing a quantity of such particles on the portion of the surface.
摘要翻译：一种制品包括（a）具有改性表面的玻璃基板，其包括玻璃表面和与玻璃表面的至少一部分接触并结合的纳米尺度无机氧化物颗粒层，和（b）设置的聚合物层与改性玻璃表面接触并结合。提高玻璃表面和聚合物表面的界面的水解稳定性的方法包括在形成玻璃表面和聚合物表面的界面之前，用纳米级无机物处理至少一部分玻璃表面的步骤氧化物颗粒通过在表面的一部分上沉积一定量的这种颗粒来改变玻璃表面。

7. 发明申请

WO2005098817A2 SYSTEM AND METHOD FOR SPEECH-TO-TEXT CONVERSION USING CONSTRAINED DICTATION IN A SPEAK-AND-SPELL MODE 审中-公开
标题翻译：使用声音和声音模式中的约束引用进行语音转换的系统和方法
公开(公告)号：WO2005098817A2
公开(公告)日：2005-10-20
申请号：PCT/US2005/009385
申请日：2005-03-21
申请人： RAO, Ashwin
发明人： RAO, Ashwin
IPC分类号： G10L11/00
CPC分类号： G10L15/08 , G10L15/193 , G10L2015/228
摘要： For improving the accuracy of a speech recognition system, for the specific task of speech-to-text (dictation style speech) translation, a constrained dictation methodology using speak-and-spell mode is disclosed. The invention is perfectly suited for modern day “text-messaging” applications wherein the number of words being dictated is very small (limited by the 140-160 characters message length constraint). Additionally, the invention adds a control on the way users interact with machines, thereby making the speech recognition task easier and improving system accuracy.
摘要翻译：为了提高语音识别系统的准确性，对于语音到文本（听写风格语音）翻译的具体任务，公开了使用说话和拼写模式的约束听写方法。本发明非常适合于现代“文本消息”应用，其中所指示的字数非常小（由140-160个字符的消息长度约束限制）。另外，本发明增加了与用户与机器交互的方式的控制，从而使得语音识别任务更容易，提高了系统的准确性。

8. 发明申请

WO2018034917A1 COMPOUNDS USEFUL FOR ALTERING THE LEVELS OF BILE ACIDS FOR THE TREATMENT OF DIABETES AND CARDIOMETABOLIC DISEASE 审中-公开
标题翻译：可用于改变胆汁酸水平的化合物用于治疗糖尿病和心脏代谢病
公开(公告)号：WO2018034917A1
公开(公告)日：2018-02-22
申请号：PCT/US2017/046183
申请日：2017-08-10
申请人： MERCK SHARP & DOHME CORP. , CALDWELL, John, P. , CAPLEN, Mary Ann , CUMMING, Jared, N. , DYKSTRA, Kevin, D. , HRUZA, Alan , LANKIN, Claire , LI, Derun , LIU, Hong , MCCRACKEN, Amy , MCKITTRICK, Brian , RAO, Ashwin , TAGAT, Jayaram, R. , TANG, Haiqun , TAOKA, Brandon, M. , VERRAS, Andreas , WALSH, Shawn, P. , WU, Wen-Lian , ZHANG, Tianyuan
发明人： CALDWELL, John, P. , CAPLEN, Mary Ann , CUMMING, Jared, N. , DYKSTRA, Kevin, D. , HRUZA, Alan , LANKIN, Claire , LI, Derun , LIU, Hong , MCCRACKEN, Amy , MCKITTRICK, Brian , RAO, Ashwin , TAGAT, Jayaram, R. , TANG, Haiqun , TAOKA, Brandon, M. , VERRAS, Andreas , WALSH, Shawn, P. , WU, Wen-Lian , ZHANG, Tianyuan
IPC分类号： A61K31/445 , A61K31/47 , C07D215/16
摘要： Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.
摘要翻译：本文描述了式I的化合物或其药学上可接受的盐。式I化合物作为Cyp8b1抑制剂，可用于预防，治疗或作为糖尿病和心血管疾病的治疗剂。

9. 发明申请

WO2011049614A2 AUTO-EMULSIFYING CLEANING SYSTEMS AND METHODS FOR USE 审中-公开
标题翻译：自动清洗清洁系统及其使用方法
公开(公告)号：WO2011049614A2
公开(公告)日：2011-04-28
申请号：PCT/US2010/002781
申请日：2010-10-19
申请人： RHODIA OPERATIONS , SEHGAL, Amit , LARA, Cecile , RAO, Ashwin , AYMES, Charles
发明人： SEHGAL, Amit , LARA, Cecile , RAO, Ashwin , AYMES, Charles
IPC分类号： C11D3/22 , C11D1/86
CPC分类号： C11D3/43 , C11D3/2068 , C11D3/2093
摘要： An auto-emulsifying cleaning composition capable of emulsifying upon contact with water, the composition in one typical embodiment comprising, based on the total weight of the composition, (a) from about 1% to about 99% by weight a blend of dibasic esters; (b) from about 1% to about 40% by weight of a blend of surfactants consisting of an organic anion neutralized with an organic cation, where either or both of the anion and the cation have surfactant properties, and the complex of which is soluble in the dibasic ester solvent blend. The blend of surfactants is typically a cationic surfactant and an anionic surfactant, which may or may not be used in conjunction with non-ionic surfactants. The dibasic esters are be derived from a blend of adipic, glutaric, and succinic diacids, and, in one particular embodiment, the blend comprises dialkyl adipate, dialkyl methylglutarate and dialkyl ethylsuccinate, wherein the alkyl groups individually comprise a C 1 -C 12 hydrocarbon group.
摘要翻译：一种自动乳化清洁组合物，其能够在与水接触时乳化，所述组合物在一个典型实施方案中基于组合物的总重量包含（a）约1重量％至约99重量％的二元酯共混物; （b）约1重量％至约40重量％的由有机阳离子中和的有机阴离子的表面活性剂的共混物，其中阴离子和阳离子中的任一个或两者具有表面活性剂性质，并且其络合物是可溶的在二元酯溶剂混合物中。表面活性剂的混合物通常是阳离子表面活性剂和阴离子表面活性剂，其可以或可以不与非离子表面活性剂结合使用。二元酯衍生自己二酸，戊二酸和琥珀酸二酸的共混物，在一个具体实施方案中，共混物包括己二酸二烷基酯，甲基戊二烷基酯和乙基琥珀酸二烷基酯，其中烷基各自包含C 1 -C 12烃基。

10. 发明申请

WO2012135262A3 METHOD AND COMPOSITION FOR TREATING STUBBLE 审中-公开
公开(公告)号：WO2012135262A3
公开(公告)日：2012-10-04
申请号：PCT/US2012/030815
申请日：2012-03-28
申请人： RHODIA OPERATIONS , CASTAING, Jean-Christophe , GROVES, Gary , RAO, Ashwin , RUCH, Thomas, E.
发明人： CASTAING, Jean-Christophe , GROVES, Gary , RAO, Ashwin , RUCH, Thomas, E.
IPC分类号： A01N63/00 , A01N25/02 , A01P13/00
摘要： A method of decomposing stubble, which is crop residue left on the ground, and a composition for treating the stubble are disclosed. The method comprises treating the stubble with the composition comprising a) polysaccharide-degrading enzyme; b) wetting agent; and, optionally, c) water and allowing the treated stubble to remain on the ground and decompose.

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