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1. 发明申请

WO2005063154A2 HYBRID EYE TRACKING SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译：混合眼睛追踪系统及相关方法
公开(公告)号：WO2005063154A2
公开(公告)日：2005-07-14
申请号：PCT/US2004/043130
申请日：2004-12-23
申请人： ALCON REFRACTIVEHORIZONS, INC. , GRAY, Gary , CAMPIN, John, A. , BOTT, Steven, E. , GIBBS, David, Michael , PETTIT, George, H.
发明人： GRAY, Gary , CAMPIN, John, A. , BOTT, Steven, E. , GIBBS, David, Michael , PETTIT, George, H.
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system and method for tracking ocular changes during a surgical procedure include directing an eye-safe optical beam toward an undilated, unparalyzed eye. A reflected optical beam is detected, and measurements are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency, and from them is calculated a change in the at least one geometric parameter. The calculated change is used to dynamically adjust the directing of laser beam shots during the surgery.
摘要翻译：用于在外科手术过程中跟踪眼睛变化的系统和方法包括将人眼安全的光束引向未扩张的未眼睛化的眼睛。检测反射光束，并且基于包含在眼睛的至少一个几何参数的反射光束中的数据以预定频率进行测量，并且从中计算至少一个几何参数的变化。计算出的变化用于动态调整手术过程中激光照射的指引。

2. 发明申请

WO2008151111A1 NOMOGRAM COMPUTATION AND APPLICATION SYSTEM AND METHOD FOR REFRACTIVE LASER SURGERY 审中-公开
标题翻译：用于激光激光手术的NOMOGRAM计算和应用系统和方法
公开(公告)号：WO2008151111A1
公开(公告)日：2008-12-11
申请号：PCT/US2008/065494
申请日：2008-06-02
申请人： ALCON REFRACTIVEHORIZONS, INC. , CAMPIN, John, Alfred , PETTIT, George, H.
发明人： CAMPIN, John, Alfred , PETTIT, George, H.
IPC分类号： A61F9/01 , A61B3/103
CPC分类号： A61F9/008 , A61B5/103 , A61F9/00804 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088
摘要： A method for optimizing a prescription for laser-ablation corneal treatment includes receiving a measured correction prescription for a current patient. Next a database of treatment outcomes on a plurality of previously treated patients is accessed. The database contains a desired correction, and an actual correction. A difference between the desired correction and the actual correction represents an over- or undercorrection resulting from surgery. From the difference data is calculated a distribution of data points as a function of correction level. From the data-point distribution is calculated a statistically based offset applicable to the correction prescription for matching actual corrections with desired corrections. From the data-point distribution is calculated a confidence interval of the data using a predetermined confidence level. The statistically based offset is then adjusted based upon the confidence interval to provide an optimized prescription. The adjusted offset is then output for use in performing a refractive procedure.
摘要翻译：用于优化激光消融角膜治疗处方的方法包括接收针对当前患者的测量的校正处方。接下来，访问多个先前治疗的患者的治疗结果的数据库。数据库包含所需的校正和实际校正。所需矫正与实际矫正之间的差异代表手术引起的过度或欠矫。根据差分数据计算数据点的分布作为校正水平的函数。从数据点分布计算出适用于校正处方的统计学偏移量，用于将实际校正与期望的校正相匹配。使用预定置信水平计算数据点分布的置信区间。然后基于置信区间来调整基于统计学的偏移，以提供优化的处方。然后输出经调整的偏移量以用于执行屈光程序。

3. 发明公开

EP1274340A2 WAVEFRONT SENSOR FOR OBJECTIVE MEASUREMENT OF AN OPTICAL SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译：具有更宽的动态范围和较小的格式TIGER CCD摄像机波前传感器
公开(公告)号：EP1274340A2
公开(公告)日：2003-01-15
申请号：EP01928145.0
申请日：2001-04-19
申请人： Alcon Universal, Ltd. , Pettit, George H.
发明人： PETTIT, George, H.
IPC分类号： A61B3/103
CPC分类号： A61B3/1015 , G01J9/00
摘要： A wavefront sensor includes an afocal relay stage for magnifying an incoming wavefront reflected from a source plane. In an exemplary application, a retina of an eye reflects an impinging light beam thereon to form a series of wavefronts. A lenslet array (23) is positioned at a reference plane (22) of the afocal relay stage (21) to receive the magnified wavefront. Further downstream is positioned a means (25) for imaging and demagnifying a focal plane image (249) of the lenslet array (23) at a final image plane (26). This demagnified image then serves as input to an anlyzer, such as a charge-coupled-device (CCD) camera.

4. 发明申请

WO2003060568A2 OPTIMIZATION OF ABLATION CORRECTION OF AN OPTICAL SYSTEM AND ASSOCIATED METHODS 审中-公开
标题翻译：光学系统的消除校正优化及相关方法
公开(公告)号：WO2003060568A2
公开(公告)日：2003-07-24
申请号：PCT/US2003/000515
申请日：2003-01-08
申请人： ALCON, INC. , CAMPIN, John, Alfred , PETTIT, George, H.
发明人： CAMPIN, John, Alfred , PETTIT, George, H.
IPC分类号： G02B
CPC分类号： A61B3/1015 , A61B5/103 , A61F9/00806 , A61F2009/00846 , A61F2009/00857 , A61F2009/00872 , A61F2009/0088
摘要： A system and method for converting measured wavefront data into an ablation profile for correcting visual defects includes providing measured wavefront data on an aberrated eye by a method such as known in the art. The measured wavefront data are correlated with accumulated data on previously treated eyes. Next an adjustment is applied to the measured wavefront data based upon the correlating step. This adjustment is applied to the measured wavefront data based upon the correlating step. This adjustment is used to form adjusted wavefront data for input to a wavefront data correction algorithm to calculate an ablation profile therefrom. The wavefront data correction algorithm may be modeled as, for example, Zernike polynomials with adjusted coefficients.
摘要翻译：用于将测量的波前数据转换成用于校正视觉缺陷的消融轮廓的系统和方法包括通过本领域已知的方法在像差眼上提供测量的波前数据。测量的波前数据与先前治疗的眼睛的累积数据相关。接下来，基于相关步骤对所测量的波前数据进行调整。基于相关步骤对该测量的波前数据进行该调整。该调整用于形成用于输入到波前数据校正算法的经调整的波前数据，以从其计算消融轮廓。波前数据校正算法可以被建模为例如具有调整系数的泽尔尼克多项式。

5. 发明申请

WO2003060568A3 OPTIMIZATION OF ABLATION CORRECTION OF AN OPTICAL SYSTEM AND ASSOCIATED METHODS 审中-公开
公开(公告)号：WO2003060568A3
公开(公告)日：2003-07-24
申请号：PCT/US2003/000515
申请日：2003-01-08
申请人： ALCON, INC. , CAMPIN, John, Alfred , PETTIT, George, H.
发明人： CAMPIN, John, Alfred , PETTIT, George, H.
IPC分类号： A61B18/18
摘要： A system (10) and method for converting measured wavefront data into an ablation profile for correcting visual defects includes providing measured wavefront (24) data on an aberrated eye by a method such as known in the art. The measured wavefront data (701) are correlated with accumulated data on previously treated eyes. Next an adjustment is applied to the measured wavefront data based upon the correlating step (707). This adjustment is used to form adjusted wavefront data (708) for input to a wavefront data correction algorithm to calculate an ablation profile (709) therefrom. The wavefront data correction algorithm may be modeled as, for example, Zemike polynomials with adjusted coefficients.

6. 发明授权

EP1696845B1 HYBRID EYE TRACKING SYSTEM AND ASSOCIATED METHODS 有权
标题翻译： HYBRID眼睛跟踪系统和相关方法
公开(公告)号：EP1696845B1
公开(公告)日：2009-02-18
申请号：EP04815239.1
申请日：2004-12-23
申请人： Alcon RefractiveHorizons, Inc.
发明人： GRAY, Gary , CAMPIN, John, A. , BOTT, Steven, E. , GIBBS, David, Michael , PETTIT, George, H.
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system (10) and method for tracking ocular changes (12, 13) during a surgical procedure include directing an eye-safe optical beam (21) toward an undilated, unparalyzed eye (90). A reflected optical beam (23) is detected (22), and measurements (17) are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency (105), and from them is calculated a change in the at least one geometric parameter (106). The calculated change is used to dynamically adjust the directing of laser beam shots (14) during the surgery.

7. 发明授权

EP2150223B1 NOMOGRAM COMPUTATION AND APPLICATION SYSTEM AND METHOD FOR REFRACTIVE LASER SURGERY 有权转让
标题翻译： NOMOGRAMMBERECHNUNG与应用系统和方法激光手术难治
公开(公告)号：EP2150223B1
公开(公告)日：2012-02-15
申请号：EP08756604.8
申请日：2008-06-02
申请人： Alcon RefractiveHorizons, Inc.
发明人： CAMPIN, John, Alfred , PETTIT, George, H.
IPC分类号： A61F9/008 , A61B3/103
CPC分类号： A61F9/008 , A61B5/103 , A61F9/00804 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088
摘要： A method for optimizing a prescription for laser-ablation corneal treatment includes receiving a measured correction prescription for a current patient. Next a database of treatment outcomes on a plurality of previously treated patients is accessed. The database contains a desired correction, and an actual correction. A difference between the desired correction and the actual correction represents an over- or undercorrection resulting from surgery. From the difference data is calculated a distribution of data points as a function of correction level. From the data-point distribution is calculated a statistically based offset applicable to the correction prescription for matching actual corrections with desired corrections. From the data-point distribution is calculated a confidence interval of the data using a predetermined confidence level. The statistically based offset is then adjusted based upon the confidence interval to provide an optimized prescription. The adjusted offset is then output for use in performing a refractive procedure.

8. 发明公开

EP1696845A2 HYBRID EYE TRACKING SYSTEM AND ASSOCIATED METHODS 有权
标题翻译： HYBRID眼睛跟踪系统和相关方法
公开(公告)号：EP1696845A2
公开(公告)日：2006-09-06
申请号：EP04815239.1
申请日：2004-12-23
申请人： Alcon RefractiveHorizons, Inc.
发明人： GRAY, Gary , CAMPIN, John, A. , BOTT, Steven, E. , GIBBS, David, Michael , PETTIT, George, H.
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system (10) and method for tracking ocular changes (12, 13) during a surgical procedure include directing an eye-safe optical beam (21) toward an undilated, unparalyzed eye (90). A reflected optical beam (23) is detected (22), and measurements (17) are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency (105), and from them is calculated a change in the at least one geometric parameter (106). The calculated change is used to dynamically adjust the directing of laser beam shots (14) during the surgery.

9. 发明公开

EP2150223A1 NOMOGRAM COMPUTATION AND APPLICATION SYSTEM AND METHOD FOR REFRACTIVE LASER SURGERY 有权转让
标题翻译： NOMOGRAMMBERECHNUNG与应用系统和方法激光手术难治
公开(公告)号：EP2150223A1
公开(公告)日：2010-02-10
申请号：EP08756604.8
申请日：2008-06-02
申请人： Alcon RefractiveHorizons, Inc.
发明人： CAMPIN, John, Alfred , PETTIT, George, H.
IPC分类号： A61F9/01 , A61B3/103
CPC分类号： A61F9/008 , A61B5/103 , A61F9/00804 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088
摘要： A method for optimizing a prescription for laser-ablation corneal treatment includes receiving a measured correction prescription for a current patient. Next a database of treatment outcomes on a plurality of previously treated patients is accessed. The database contains a desired correction, and an actual correction. A difference between the desired correction and the actual correction represents an over- or undercorrection resulting from surgery. From the difference data is calculated a distribution of data points as a function of correction level. From the data-point distribution is calculated a statistically based offset applicable to the correction prescription for matching actual corrections with desired corrections. From the data-point distribution is calculated a confidence interval of the data using a predetermined confidence level. The statistically based offset is then adjusted based upon the confidence interval to provide an optimized prescription. The adjusted offset is then output for use in performing a refractive procedure.

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