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    • 9. 发明申请
    • ANILIDE DERIVATIVES AS FUNGICIDES
    • 抗生素衍生物作为防腐剂
    • WO1995025723A1
    • 1995-09-28
    • PCT/GB1995000570
    • 1995-03-16
    • AGREVO UK LIMITEDRIORDAN, Peter, DominicBODDY, Ian, KennethOSBOURN, Susan, Elisabeth
    • AGREVO UK LIMITED
    • C07D213/82
    • C07D213/81A01N43/10A01N43/40A01N43/50A01N43/52A01N43/54A01N43/60A01N43/713A01N43/82A01N43/84A01N43/90A01N47/12A01N47/20A01N59/20C07D213/82C07D231/12C07D233/56C07D239/28C07D239/30C07D239/34C07D239/38C07D239/42C07D239/52C07D239/56C07D241/24C07D249/08C07D333/38C07D401/12C07D413/12C07D417/12
    • Compounds of formula (I), wherein: X is O or S; A is a 6 membered heteroaryl group comprising at least one nitrogen atom, which is optionally substituted by one or more of the group R ; R is alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl or amino, (each of which is optionally substituted), Y -X-, halogen, cyano, nitro, acyl, acyloxy, optionally substituted heterocyclyl or optionally substituted phenyl; or two adjacent groups together with the carbon atoms to which they are attached can form an optionally substituted benzo ring; R has the same meaning as R or two adjacent groups together with the carbon atoms to which they are attached can form an optionally substituted heterocyclic ring; Y is alkyl, cycloalkyl, cycloalkenyl, alkenyl or alkynyl, each of which is optionally substituted, hydrogen or acyl; Y has the same meaning as Y or is optionally substituted phenyl or optionally substituted heterocyclyl; Z is C(=X )-X -R , cyano, nitro, amino, acyl, optionally substituted heterocyclyl, -C(R )=N-OR or -C(R )=N-NR R ; R is alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl or heterocyclyl, each of which is optionally substituted, hydrogen or an inorganic or organic cationic group ; X and X , which may be the same or different, are O or S , R , R and R , which may be the same or different, are alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl or heterocyclyl, each of which is optionally substituted or hydrogen or R and R together with the atom(s) to which they are attached can form a ring; n is 0 to 4, together with complexes with metal salts, as well as salts with bases of compounds which are acids and salts with acids of compounds which are bases, have fungidal activity.
    • 式(I)化合物,其中:X为O或S; A是包含至少一个氮原子的6元杂芳基,其任选被一个或多个R 2基团取代; R 1是烷基,环烷基,环烯基,烯基,炔基或氨基(各自任选被取代),Y 1 -X - ,卤素,氰基,硝基,酰基,酰氧基,任选取代的杂环基或任选取代 苯基; 或两个相邻基团与它们所连接的碳原子一起形成任选取代的苯并环; R 2具有与R 1相同的含义或两个相邻基团与它们所连接的碳原子一起形成任选取代的杂环; Y是烷基,环烷基,环烯基,烯基或炔基,其各自任选被取代,氢或酰基; Y 1具有与Y相同的含义或任选取代的苯基或任选取代的杂环基; Z是C(= X 1)-X 2 -R 3,氰基,硝基,氨基,酰基,任选取代的杂环基,-C(R 5)= N-OR 6或 - C(R <5>)= N-NR <6> - [R <7>; R 3是烷基,环烷基,环烯基,烯基,炔基,苯基或杂环基,其各自任选被取代,氢或无机或有机阳离子基团; X 1和X 2可以相同或不同,是O或S,R 5,R 6和R 7可以相同或不同,是烷基,环烷基 ,环烯基,烯基,炔基,苯基或杂环基,其各自为任选取代的或氢或R 6和R 7与它们所连接的原子一起形成环; n为0至4,以及与金属盐的络合物,以及与作为碱的化合物的酸的化合物的碱的盐,与具有杀真菌活性的化合物的酸形成的盐。
    • 10. 发明申请
    • CHROMONES USEFUL AS FUNGICIDES
    • CHROMONES有用作为防腐剂
    • WO1998027080A1
    • 1998-06-25
    • PCT/GB1997003368
    • 1997-12-18
    • AGREVO UK LIMITEDMACRITCHIE, Jacqueline, AnneO'MAHONY, Mary, JosephineLINDELL, Stephen, David
    • AGREVO UK LIMITED
    • C07D311/22
    • C07D215/22A01N43/14A01N43/42A01N43/50A01N43/653C07D311/22C07D311/30C07D335/06
    • Compounds of formula (I) in which Z is O, S(O)n or NR, and a) P is WR ; and Q is R or W R or b) P is R and Q is R ; and when Z is S(O)n or NR, and Q is W R ; P can be R ; W and W , which may be the same or different, are O, S(O)n, N(R ), N(R )N(R ), N(R )O or ON(R ); R is hydrogen, or an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, phenyl or heterocyclyl group; R, R , R , R , R and R , which may be the same or different, have the same meaning as R , or are acyl, or any two adjacent R groups together with the atoms to which they are attached form an optionally substituted ring which may contain other heteroatoms; R and R , which may be the same or different, have the same meaning as R (heterocyclyl groups being carbon linked) or are cyano, nitro, COOR or COR , each X, which may be the same as or different from any other X, is halogen, CN, NO2, SF5, B(OH)2, trialkylsilyl or a group E, OE or SE where E is a group as defined hereinbefore for R or is optionally substituted amino; or two adjacent groups X together with the atoms to which they are attached form an optionally substituted carbocyclic or heterocyclic ring; n is 0, 1 or 2; and p is 0 to 4 have fungicidal activity.
    • 其中Z为O,S(O)n或NR的式(I)化合物,和a)P为WR 2; 且Q为R 1或W 2 R 2a或b)P为R a且Q为R b; 当Z为S(O)n或NR时,Q为W 2 R 2a; P可以是R 1; W和W 2可以相同或不同,是O,S(O)n,N(R 3),N(R 3)N(R 4),N(R 3)O或ON(R 3); R 1是氢或任选取代的烷基,烯基,炔基,环烷基,环烯基,环炔基,苯基或杂环基; R 1,R 2,R 2a,R 2b,R 3和R 4可以相同或不同,具有与R 1相同的含义,或是酰基,或 任何两个相邻的R基团与它们所连接的原子一起形成可以含有其它杂原子的任选取代的环; R a和R b可以相同或不同,具有与R 1(杂环基是碳连接的)相同的含义或氰基,硝基,COOR 1或COR 1, 每个X可以与任何其它X相同或不同,是卤素,CN,NO2,SF5,B(OH)2,三烷基甲硅烷基或基团E,OE或SE,其中E是R定义的基团 或是任选取代的氨基; 或两个相邻基团X与它们所连接的原子一起形成任选取代的碳环或杂环; n为0,1或2; p为0〜4具有杀菌活性。