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1. 发明申请

WO2013062635A3 AUTOMATED CONVERSION BETWEEN SFC AND HPLC 审中-公开
公开(公告)号：WO2013062635A3
公开(公告)日：2013-05-02
申请号：PCT/US2012/042844
申请日：2012-06-16
申请人： AGILENT TECHNOLOGIES, INC. , WIKFORS, Edwin, E. , FOGELMAN, Kimber , BERGER, Terry, A.
发明人： WIKFORS, Edwin, E. , FOGELMAN, Kimber , BERGER, Terry, A.
IPC分类号： G01N30/02 , G01N30/22 , G01N30/32
摘要： An apparatus, system, and process of converting a standard, high performance liquid chromatography (HPLC) flow path to a flow path suitable for supercritical fluid chromatography (SFC) are described. This reversible technique is applied to a variety of flow configurations including binary, high pressure solvent mixing systems and quaternary, low pressure solvent mixing systems than can be conventionally operated or automated. The technique is generally applied to the fields of supercritical fluid chromatography and high pressure liquid chromatography, but users skilled in the art will find utility for any flow system where pressurization components must be periodically applied to and removed from both ends of a flow stream in an automated manner.

2. 发明申请

WO2012040252A3 SYSTEM AND PROCESS FOR AN ACTIVE DRAIN FOR GAS-LIQUID SEPARATORS 审中-公开
公开(公告)号：WO2012040252A3
公开(公告)日：2012-03-29
申请号：PCT/US2011/052426
申请日：2011-09-20
申请人： AURORA SFC SYSTEMS, INC. , FOGELMAN, Kimber, D. , WIKFORS, Edwin, E. , BERGER, Terry, A.
发明人： FOGELMAN, Kimber, D. , WIKFORS, Edwin, E. , BERGER, Terry, A.
IPC分类号： B01D15/40
摘要： An apparatus and process to effectively create an active drain for high and low pressure gas-liquid separator. The invention accomplishes a deterministic drainage rate of variable volume and viscosity liquid fractions from the separator. The mechanisms and methods thereof create a flow path from the separator that dramatically favors controlled liquid flow over a wide range of flow rates and viscosities while restricting gas flow. The invention is a superior method of drainage over conventional systems that employ pressure, vacuum, isolation valves and/or passive flow restrictors to achieve drainage of the separators. The embodiments are primarily directed to the fields of preparative supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE). An advantage of one embodiment allows the economical conversion of typical HPLC systems to state of-the-art supercritical fluid chromatography (SFC) systems with minimal modification to system components.

3. 发明公开

EP2618905A2 SYSTEM AND PROCESS FOR AN ACTIVE DRAIN FOR GAS-LIQUID SEPARATORS 有权
标题翻译：用于气液分离器主动排放的系统和方法
公开(公告)号：EP2618905A2
公开(公告)日：2013-07-31
申请号：EP11827390.3
申请日：2011-09-20
申请人： Agilent Technologies, Inc.
发明人： FOGELMAN, Kimber, D. , WIKFORS, Edwin, E. , BERGER, Terry, A.
IPC分类号： B01D15/40
摘要： A device includes a gas-liquid separator that receives and separates a biphasic pressurized flow stream and delivers flow to at least one exit port enriched in vapor phase composition and at least one exit port enriched in liquid phase composition. The device further includes a low restriction inlet conduit in communication with the separator exit port enriched in liquid phase composition, and a positive displacement pump having an inlet port in communication with the inlet conduit to receive flow from the gas-liquid separator and an outlet port in communication with an outlet conduit.
摘要翻译：一种有效地产生用于高低压气液分离器的主动排放装置和方法。本发明实现了来自分离器的可变体积和粘度液体馏分的确定性排放速率。其机制和方法从分离器产生流动路径，该流动路径显着有利于在宽范围的流速和粘度下控制液体流动，同时限制气体流动。本发明是一种优于使用压力，真空，隔离阀和/或被动限流器来实现分离器排水的常规系统的排水方法。这些实施方案主要涉及制备型超临界流体色谱法（SFC）和超临界流体萃取（SFE）领域。一个实施方案的优点允许将典型的HPLC系统经济转换为最新技术的超临界流体色谱（SFC）系统，对系统组分进行最小修改。

4. 发明授权

EP2618905B1 SYSTEM AND PROCESS FOR AN ACTIVE DRAIN FOR GAS-LIQUID SEPARATORS 有权
公开(公告)号：EP2618905B1
公开(公告)日：2019-11-13
申请号：EP11827390.3
申请日：2011-09-20
申请人： Agilent Technologies, Inc.
发明人： FOGELMAN, Kimber, D. , WIKFORS, Edwin, E. , BERGER, Terry, A.
IPC分类号： B01D15/40 , B01D19/00

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