专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2007067398A2 SOLVENTLESS METHOD FOR FORMING A COATING 审中-公开
标题翻译：用于形成涂料的无溶剂方法
公开(公告)号：WO2007067398A2
公开(公告)日：2007-06-14
申请号：PCT/US2006/045710
申请日：2006-11-29
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , HOSSAINY, Syed, Faiyaz, Ahmed , LUDWIG, Florian , SRIDHARAN, Srinivasan , PACETTI, Stephen, D.
发明人： HOSSAINY, Syed, Faiyaz, Ahmed , LUDWIG, Florian , SRIDHARAN, Srinivasan , PACETTI, Stephen, D.
CPC分类号： A61L31/10 , A61L31/16 , A61L2300/606 , A61L2420/02 , B05D3/0254 , B05D3/067 , B05D3/068
摘要： Provided herein are medical device having a coating substantially free from effects of drying kinetics and methods of forming the coating.
摘要翻译：本文提供了具有基本上没有干燥动力学影响的涂层和形成涂层的方法的医疗装置。

2. 发明申请

WO2007005180A2 INTRACORONARY DEVICE AND METHOD OF USE THEREOF 审中-公开
标题翻译：内窥镜装置及其使用方法
公开(公告)号：WO2007005180A2
公开(公告)日：2007-01-11
申请号：PCT/US2006/021964
申请日：2006-06-06
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , CONSIGNY, Paul , ASONGWE, Gabriel , MICHAELS, Mary Beth , MICHAL, Gene , MANDRUSOV, Evgenia , LEE, Jeong , LUDWIG, Florian , HENCKEL, John Eric , SCIACCA, Joseph J. , BUECHE, Ken , THORNTON, Richard Todd , URRABAZO, Fidel Albert , WIEGAND, Daniel
发明人： CONSIGNY, Paul , ASONGWE, Gabriel , MICHAELS, Mary Beth , MICHAL, Gene , MANDRUSOV, Evgenia , LEE, Jeong , LUDWIG, Florian , HENCKEL, John Eric , SCIACCA, Joseph J. , BUECHE, Ken , THORNTON, Richard Todd , URRABAZO, Fidel Albert , WIEGAND, Daniel
IPC分类号： C12N5/00 , C12N13/00 , A61K35/28 , A61P9/00
CPC分类号： A61K38/18 , A61K35/545 , A61K38/19 , A61K2300/00
摘要： Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
摘要翻译：通过机械，化学和生物学方法和系统，将治疗细胞和药剂移植到生物体的靶位点。

3. 发明申请

WO2009070211A1 SUSTAINED RELEASE OF APO A-I MIMETIC PEPTIDES AND METHODS OF PRODUCING THEM 审中-公开
标题翻译： APO A-I模拟肽的持续释放及其生产方法
公开(公告)号：WO2009070211A1
公开(公告)日：2009-06-04
申请号：PCT/US2008/012794
申请日：2008-11-14
申请人： ABBOTT CARDIOVASCULAR SYSTEMS INC. , HOSSAINY, Syed, F.A. , WAN, Jinping , DAVALIAN, Dariush , LUDWIG, Florian , MURASE, Katsuyuki
发明人： HOSSAINY, Syed, F.A. , WAN, Jinping , DAVALIAN, Dariush , LUDWIG, Florian , MURASE, Katsuyuki
IPC分类号： A61K9/14 , A61K9/16 , A61K38/17 , A61K9/50
CPC分类号： A61K31/661 , A61K9/1647 , A61K9/5084 , A61K38/00
摘要： A method including advancing a delivery device through a lumen of a blood vessel to a particular region in the blood vessel; and introducing a composition including a sustained-release carrier and an apolipoprotein A-I (apo A-I) synthetic mimetic peptide into a wall of the blood vessel at the particular region or a perivascular site, wherein the peptide has a property that renders the peptide effective in reverse cholesterol transport. A composition including an apolipoprotein A-I (apo A-I) synthetic peptide, or combination of an apo A-I synthetic mimetic peptide and an Acyl CoA cholesterol: acyltransferase (ACAT) inhibitor in a form suitable for delivery into a blood vessel, the peptide including an amino acid sequence in an order reverse to an order of various apo A-I mimetic peptides, or endogenous apo A-I analogs, or a chimera of helix 1 and helix 9 of endogenous apo A-I.
摘要翻译：一种方法，包括使递送装置通过血管腔推进到血管中的特定区域; 并且将包含缓释载体和载脂蛋白AI（apo AI）合成模拟肽的组合物引入血管的特定区域或血管周围部位的壁中，其中所述肽具有使肽有效反转的性质胆固醇运输。以适合递送到血管中的形式包含载脂蛋白AI（apo AI）合成肽或者apo AI合成模拟肽和酰基CoA胆固醇：酰基转移酶（ACAT）抑制剂的组合物，所述肽包括氨基酸序列的顺序与各种apo AI模拟肽或内源性apo AI类似物或内源性apo AI的螺旋1和螺旋9的嵌合体的顺序相反。

4. 发明申请

WO2003103510A1 METHODS AND DEVICES FOR FACILITATING THE FORMATION OF CONNECTIONS BETWEEN TISSUE STRUCTURES 审中-公开
标题翻译：促进组织结构之间连接形成的方法和装置
公开(公告)号：WO2003103510A1
公开(公告)日：2003-12-18
申请号：PCT/US2003/018045
申请日：2003-06-05
申请人： SHARKAWY, A. Adam , LUDWIG, Florian
发明人： SHARKAWY, A. Adam , LUDWIG, Florian
IPC分类号： A61B17/08
CPC分类号： A61B17/11 , A61B17/0643 , A61B17/320016 , A61B2017/00252 , A61B2017/1107 , A61B2017/1139
摘要： Methods and devices are provided to facilitate the natural formation of a connection between tissue structures within the body. Certain of the subject methods provide for the formation on an anastomotic site between a graft vessel and a native vessel, such as vessels of the cardiovasculature, peripheral vasculature and neuro-vasculature, angiogenic, by means of facilitating angiogenic and/or arteriogenic processes at one or more selected points of contact or close proximity between the vessels. The subject devices include a mechanism for positioning or situating one vessel adjacent to another vessel, in situ, wherein a selected portion of each vessel is in contact or in close proximity with the other vessel such that a natural bond is formed between the outer tissue surfaces of the vessels at the point of contact or close proximity followed by the naturally occurring angiogenic and/or arteriogenic processes of the body.
摘要翻译：提供了方法和装置以促进身体内的组织结构之间的连接的自然形成。某些主题方法提供了在移植血管和天然血管之间的吻合部位上的形成，例如血管系统的血管，外周脉管系统和神经脉管系统，血管生成，通过促进血管生成和/或动脉生成过程在一个或更多选择的接触点或紧密接近。本发明的装置包括用于在原位置定位或邻近另一容器的一个容器的机构，其中每个容器的选定部分与另一个容器接触或紧密接近，使得在外部组织表面的血管在接触点或紧密接近处，随后是身体的天然存在的血管生成和/或动脉发生过程。

5. 发明申请

WO2003037400A2 METHODS AND DEVICE COMPOSITIONS FOR THE RECRUITMENT OF CELLS TO BLOOD CONTACTING SURFACES IN VIVO 审中-公开
标题翻译：用于血管生成细胞接种血管表面的方法和装置组合物
公开(公告)号：WO2003037400A2
公开(公告)日：2003-05-08
申请号：PCT/US2002/035224
申请日：2002-10-31
申请人： VENTRIGRAFT, INC. , LUDWIG, Florian , SHARKAWY, A., Adam
发明人： LUDWIG, Florian , SHARKAWY, A., Adam
IPC分类号： A61M
CPC分类号： A61L27/34 , A61K38/00 , A61K38/1825 , A61K38/1866 , A61K38/193 , A61K47/6957 , A61L27/3604 , A61L27/3641 , A61L27/3839 , A61L27/58 , A61K2300/00
摘要： Methods and compositions for recruiting cells circulating in the blood stream of a subject to a blood contacting surface, and in particular, devices and methods for recruiting endothelial cells to a blood contacting surface of a prosthesis as well as engineering a self-endothelializing graft in vivo by recruitment of circulating endothelial progenitor cells (EPCs) to form a neo-endothelium on a prosthetic structure.
摘要翻译：用于将在受试者的血流中循环的细胞募集到血液接触表面的方法和组合物，特别是用于将内皮细胞募集到假体的血液接触表面的装置和方法以及在体内工程化自体内皮移植物通过募集循环内皮祖细胞（EPCs）在假体结构上形成新内皮。

6. 发明申请

WO2009070210A2 SUSTAINED RELEASE OF APO A-I MIMETIC PEPTIDES AND METHODS OF TREATMENT 审中-公开
标题翻译： APO A-I模拟肽的持续释放和治疗方法
公开(公告)号：WO2009070210A2
公开(公告)日：2009-06-04
申请号：PCT/US2008/012793
申请日：2008-11-14
申请人： ABBOTT CARDIOVASCULAR SYSTEMS INC. , MURASE, Katsuyuki , WAN, Jinping , STANKUS, John , DAVALIAN, Dariush , LUDWIG, Florian
发明人： MURASE, Katsuyuki , WAN, Jinping , STANKUS, John , DAVALIAN, Dariush , LUDWIG, Florian
IPC分类号： A61K9/14 , A61K9/16 , A61K38/17 , A61K9/50
CPC分类号： A61K31/661 , A61K9/0019 , A61K9/0024 , A61K9/127 , A61K9/1647 , A61K9/5153 , A61K38/17
摘要： A method including advancing a delivery device through a lumen of a blood vessel to a particular region in the blood vessel; and introducing a composition including a sustained-release carrier and an apolipoprotein A-I (apo A-I) synthetic mimetic peptide into a wall of the blood vessel at the particular region or a perivascular site, wherein the peptide has a property that renders the peptide effective in reverse cholesterol transport. A composition including an apolipoprotein A-I (apo A-I) synthetic peptide, or combination of an apo A-I synthetic mimetic peptide and an Acyl CoA cholesterol: acyltransferase (ACAT) inhibitor in a form suitable for delivery into a blood vessel, the peptide including an amino acid sequence in an order reverse to an order of various apo A-I mimetic peptides, or endogenous apo A-I analogs, or a chimera of helix 1 and helix 9 of endogenous apo A-I.
摘要翻译：一种方法，包括使递送装置通过血管腔推进到血管中的特定区域; 并且将包含缓释载体和载脂蛋白AI（apo AI）合成模拟肽的组合物引入血管的特定区域或血管周围部位的壁中，其中所述肽具有使肽有效反转的性质胆固醇运输。以适合递送到血管中的形式包含载脂蛋白AI（apo AI）合成肽或者apo AI合成模拟肽和酰基CoA胆固醇：酰基转移酶（ACAT）抑制剂的组合物，所述肽包括氨基酸序列的顺序与各种apo AI模拟肽或内源性apo AI类似物或内源性apo AI的螺旋1和螺旋9的嵌合体的顺序相反。

7. 发明申请

WO2003037400A3 METHODS AND DEVICE COMPOSITIONS FOR THE RECRUITMENT OF CELLS TO BLOOD CONTACTING SURFACES IN VIVO 审中-公开
公开(公告)号：WO2003037400A3
公开(公告)日：2003-05-08
申请号：PCT/US2002/035224
申请日：2002-10-31
申请人： LUDWIG, Florian , SHARKAWY, A., Adam
发明人： LUDWIG, Florian , SHARKAWY, A., Adam
IPC分类号： A01N1/02
摘要： Methods and compositions for recruiting cells circulating in the blood stream of a subject to a blood contacting surface, and in particular, devices and methods for recruiting endothelial cells to a blood contacting surface of a prosthesis as well as engineering a self-endothelializing graft in vivo by recruitment of circulating endothelial progenitor cells (EPCs) to form a neo-endothelium on a prosthetic structure.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式