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1. 发明申请

WO1998006452A1 PROTECTIVE SHEATH FOR CATHETER BALLOONS 审中-公开
标题翻译：导管气球保护管
公开(公告)号：WO1998006452A1
公开(公告)日：1998-02-19
申请号：PCT/US1997014072
申请日：1997-08-11
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , WILLIAMS, Kerry , TAVISH, Rebecca, Len , HOWARD, Lawrence, E. , PATEL, Udayan, G.
IPC分类号： A61M25/10
CPC分类号： A61M25/1029 , A61M25/10 , A61M25/1027 , A61M2025/1081
摘要： A polymeric heat shrinkable tubular sheath for mounting about a balloon on a dilatation catheter by heat treating at a temperature which does not detrimentally effect the properties of the balloon to shrink the sheath onto the balloon. The tubular sheath is preferably heated to a temperature above body temperature, e.g. 40
摘要翻译：一种聚合物热收缩管状护套，用于通过在不会不利地影响气囊的性质以将护套收缩到气囊上的温度下进行热处理来在扩张导管上安装气球周围。管状护套优选加热至高于体温的温度，例如， 40 <100℃，优选小于85℃，将护套热收缩到气球上。目前优选的聚合物材料是乙烯（75％）和丙烯酸甲酯（25％）的共聚物。热收缩护套具有内腔，其最小尺寸足够大以便于护套在膨胀气囊的外部上的前进，而不需要在热收缩之前由医师或其他操作者进行大量手动操作。

2. 发明申请

WO1996015825A1 CATHETER WITH AN EXPANDABLE PERFUSION LUMEN 审中-公开
标题翻译：具有可膨胀的灌注液的导管
公开(公告)号：WO1996015825A1
公开(公告)日：1996-05-30
申请号：PCT/US1995012676
申请日：1995-10-02
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , THORNTON, Troy, L.
IPC分类号： A61M29/02
CPC分类号： A61M25/104 , A61M2025/1086 , A61M2025/1095
摘要： An intravascular catheter such as a dilatation catheter for angioplasty procedures which is provided with a perfusion lumen extending which is expanded when disposed within a desired location with the patient's body lumen so as to increase the perfusion of body fluid such as oxygenated blood through the perfusion lumen.
摘要翻译：一种血管内导管，例如用于血管成形术程序的扩张导管，其设置有灌注腔，其延伸，当与患者的体腔布置在期望位置时，该扩张腔被扩张，以便增加体液如通过灌注腔的氧合血液的灌注。

3. 发明申请

WO1993023107A1 INTRALUMINAL CATHETER WITH A COMPOSITE SHAFT 审中-公开
标题翻译：具有复合轴的中央导管
公开(公告)号：WO1993023107A1
公开(公告)日：1993-11-25
申请号：PCT/US1993004436
申请日：1993-05-10
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , AINSWORTH, Robert, D. , WAND, Bruce, H. , JACOBSON, David, T.
IPC分类号： A61M25/00
CPC分类号： A61M25/104 , A61M25/005 , A61M2025/0183 , A61M2025/1093
摘要： A composite tubular element for intravascular catheters, such as fixed-wire dilatation catheters and guiding and angiographic catheters, which is formed by braiding strands formed from an intimate mixture of polymeric matrix materials, such as fibers and powders, having a relatively low melting point and high strength reinforcing fibers having a relatively high melting point into a tubular element, heating the braided tubular element to melt the low melting point matrix materials and flow around the reinforcing fibers to form a matrix. A thermoplastic jacket or coating may then be extruded or otherwise applied to the exterior of the braided tubular element.

4. 发明申请

WO1993015781A1 COMPOSITE MATERIAL HAVING A LUBRICOUS SURFACE FOR CATHETER USE 审中-公开
标题翻译：具有用于导管器使用的润滑表面的复合材料
公开(公告)号：WO1993015781A1
公开(公告)日：1993-08-19
申请号：PCT/US1993001225
申请日：1993-02-08
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , CHENG, Tai, Chun , HARRINGTON, Douglas, C. , AINSWORTH, Robert, D.
IPC分类号： A61M05/32
CPC分类号： A61M25/104 , A61M25/0045 , A61M2025/1079
摘要： A low friction intravascular catheter (10) component formed of a polymer matrix having incorporated within the matrix a finely divided lubricous particulate. The polymer matrix preferably is a thermoplastic polymer and suitable lubricous particulate includes graphite, molybdenum disulfide, TiC, MoC, graphite difluoride, and fluoropolymers. Typical components made of this low-friction material include the inner (12) or outer tubular members (14) of fixed-wire and over-the-wire dilatation catheters (10). A polysiloxane fluid may be incorporated within the matrix along with the lubricous particulate matter.
摘要翻译：低摩擦血管内导管（10）组分由聚合物基质形成，所述聚合物基质在基体内并入细碎的润滑颗粒。聚合物基质优选是热塑性聚合物，合适的润滑颗粒包括石墨，二硫化钼，TiC，MoC，二氧化碳石墨和含氟聚合物。由该低摩擦材料制成的典型部件包括固定线和线上扩张导管（10）的内部（12）或外部管状构件（14）。聚硅氧烷流体可与润滑颗粒物质一起并入基质内。

5. 发明申请

WO1993001856A1 LOW PROFILE PERFUSION-TYPE DILATATION CATHETER 审中-公开
标题翻译：低剖面渗透型泄放导管
公开(公告)号：WO1993001856A1
公开(公告)日：1993-02-04
申请号：PCT/US1992006121
申请日：1992-07-23
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , SIRHAN, Motasium, M. , LEROHL, Andrew , FERNANDO, Jovito, L.
IPC分类号： A61M29/02
CPC分类号： A61M25/104 , A61M2025/0183
摘要： A balloon dilatation catheter which has a coiled supporting element (17) disposed within a guidewire receiving inner lumen (11) extending within the interior of the balloon (16). Substantially, lower profiles can be obtained with catheters of this type, particularly with perfusion-type dilatation catheters with little chance that the inner member will collapse when the balloon is inflated to high pressures. Additionally, the coiled supporting element (17) provides much smoother transitions at the ends of the balloon and thereby improves the trackability of the catheter over the guidewire.

6. 发明申请

WO1996021488A1 MAGNETIC GUIDEWIRE ANCHORING APPARATUS AND METHOD FOR FACILITATING EXCHANGE OF AN OVER-THE-WIRE CATHETER 审中-公开
标题翻译：磁导管锚固装置和方法，用于促进交流电线
公开(公告)号：WO1996021488A1
公开(公告)日：1996-07-18
申请号：PCT/US1996000468
申请日：1996-01-11
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , PFLUEGER, Russell
IPC分类号： A61M25/01
CPC分类号： A61M25/0169 , A61B2017/22049 , A61M25/0127 , A61M25/09 , A61M2025/09125
摘要： A magnetic guidewire anchoring apparatus for deterring longitudinal movement of a guidewire during manipulation or exchange of an over-the-wire catheter. The magnetic guidewire anchoring apparatus may comprise permanent magnet(s) or electromagnet(s), and may incorporate configuration attributes and/or attendent mounting brackets or other apparatus to facilitate positioning of the apparatus on the outer surface of a catheter through which a guidewire extends.
摘要翻译：一种用于在操纵或更换线上导管期间阻止导丝的纵向运动的磁导丝锚固装置。磁导丝锚固装置可以包括永磁体或电磁体，并且可以包括配置属性和/或出席安装支架或其他装置，以便于将装置定位在导丝的外表面上，导丝延伸穿过。

7. 发明申请

WO1996003163A1 COMPOSITE POLYESTER MATERIAL HAVING A LUBRICOUS SURFACE 审中-公开
标题翻译：具有润滑表面的复合聚酯材料
公开(公告)号：WO1996003163A1
公开(公告)日：1996-02-08
申请号：PCT/US1995008836
申请日：1995-07-17
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , CHENG, Tai, C. , HARRINGTON, Douglas, C. , AINSWORTH, Robert, D.
IPC分类号： A61L29/00
CPC分类号： A61L29/14 , A61L29/126 , A61M25/0045 , A61M25/104
摘要： A low friction intravascular catheter component formed of a polyester matrix having incorporated therein a finely divided lubricous particulate which is preferably one or more suitable lubricous particulate selected from the group consisting of graphite, molybdenum disulfide, TiC, MoC, graphite difluoride, and fluoropolymers. The polyester is preferably a copolymer with a predominant amount of polybutylene terephthalate and lesser amounts of components such as polytetramethylene ether glycol which has been esterified with dimethyl terephthalate, e.g. HYTREL3. Typical components made of this low-friction material include the inner or outer tubular members of fixed-wire and over-the-wire dilatation catheters. A polysiloxane fluid may be incorporated within the matrix along with the lubricous particulate matter.
摘要翻译：由聚酯基质形成的低摩擦血管内导管部件，其中并入有精细分散的润滑颗粒，其优选为选自石墨，二硫化钼，TiC，MoC，二氟化石墨和含氟聚合物中的一种或多种合适的润滑颗粒。聚酯优选是具有主要量的聚对苯二甲酸丁二醇酯和较少量的已经用对苯二甲酸二甲酯酯化的聚四亚甲基醚二醇的组分的共聚物。 HYTREL3。由该低摩擦材料制成的典型部件包括固定线和线上扩张导管的内部或外部管状构件。聚硅氧烷流体可与润滑颗粒物质一起并入基质内。

8. 发明申请

WO1996003162A1 INTRALUMINAL CATHETER WITH HIGH STRENGTH PROXIMAL SHAFT 审中-公开
标题翻译：具有高强度接头轴的管内导管
公开(公告)号：WO1996003162A1
公开(公告)日：1996-02-08
申请号：PCT/US1995008635
申请日：1995-07-10
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , AINSWORTH, Robert, D. , CHENG, Tai, C. , WASICEK, Lawrence, D.
IPC分类号： A61L29/00
CPC分类号： A61M25/104 , A61L29/06 , A61L29/14 , A61M25/0045 , A61M25/0054 , C08L71/12 , C08L81/06 , C08L71/00
摘要： A balloon dilatation having a relatively stiff proximal catheter shaft which is formed at least in part of an engineering thermoplastic polymer material with a tensile strength of at least about 10,000 psi, an elongation of at least 50 % and a tensile modulus of at least 300,000 psi. The polymer is preferably an aromatic polymer, and particularly polyetheretherketone.
摘要翻译：具有相对刚性的近端导管轴的球囊扩张，其至少部分地由至少约10,000psi的拉伸强度，至少50％的伸长率和至少300,000psi的拉伸模量形成在工程热塑性聚合物材料中。聚合物优选为芳族聚合物，特别是聚醚醚酮。

9. 发明申请

WO1995019800A2 GUIDEWIRE WITH SUPERELASTIC DISTAL PORTION 审中-公开
标题翻译：带超音速远程部件的GUIDEWIRE
公开(公告)号：WO1995019800A2
公开(公告)日：1995-07-27
申请号：PCT/US1994000468
申请日：1994-01-14
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , ABRAMS, Robert, M.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , CHAN, Randy, S. , BURPEE, Janet, W.
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61L31/022 , A61L2400/16 , A61M2025/09083 , A61M2025/09141 , A61M2025/09175 , A61M2205/0266 , C22C14/00 , C22C30/00 , C22F1/006
摘要： An improved guidewire for advancing a catheter within a body lumen which has a high strength proximal portion, a distal portion formed of superelastic alloy and a connector formed of superelastic alloy to provide a torque transmitting coupling between the distal end of the proximal portion and the proximal end of the distal portion. The superelastic alloy elements are preferably cold worked and then heat treated at a temperature well above the austenite-to-martensite transformation temperature, while being subjected to longitudinal stresses equal to about 5 to about 50 % of the room temperature yield stress to impart to the metal a straight "memory". The guiding member using such improved material exhibits a stress induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of at least 70 ksi for solid members and at least 50 ksi for tubular members with a broad recoverable strain of at least about 4 % during the phase transformation.
摘要翻译：一种改进的导丝，用于将导管推进在具有高强度近端部分的体腔内，由超弹性合金形成的远端部分和由超弹性合金形成的连接器，以在近端部分的远端和近端部分之间提供扭矩传递联接远端部分的末端。超弹性合金元素优选是冷加工的，然后在远高于奥氏体 - 马氏体转变温度的温度下进行热处理，同时经受等于室温屈服应力的约5至约50％的纵向应力，以赋予金属直“记忆”。使用这种改进的材料的引导构件在固体构件具有至少70ksi的异常高的恒定屈服强度和至少50ksi的管状构件的情况下表现出应力诱导的奥氏体 - 马氏体相变，其具有至少大约的可恢复应变在相变期间为4％。

10. 发明申请

WO1994002197A1 LOW PROFILE CATHETER WITH EXPANDABLE OUTER TUBULAR MEMBER 审中-公开
标题翻译：具有可扩展的外部管状构件的低剖面导管
公开(公告)号：WO1994002197A1
公开(公告)日：1994-02-03
申请号：PCT/US1993007043
申请日：1993-07-27
申请人： ADVANCED CARDIOVASCULAR SYSTEMS, INC.
发明人： ADVANCED CARDIOVASCULAR SYSTEMS, INC. , MUNI, Ketan, P. , SIRHAN, Motasim, M.
IPC分类号： A61M29/02
CPC分类号： A61M25/1029 , A61M25/104 , A61M2025/0183 , A61M2025/1059
摘要： A dilatation catheter with a catheter shaft (10) having an outer tubular member (13) with an expandable distal section (17) which expands elastically upon the introduction of fluid under a pressure within a first pressure range to a larger diameter and which contracts by elastic recoil upon the withdrawal of the inflation fluid. The expandable distal section is relatively noncompliant at pressures above the first pressure range. Preferably, the dilatation catheter has an inflatable member or balloon (16) disposed distal to the expandable distal section which is formed of the same polymeric material as the expandable distal section and is in fluid communication with the expandable inner lumen within the expandable distal section.
摘要翻译：具有导管轴（10）的扩张导管具有外管状构件（13），其具有可膨胀远端部分（17），其在第一压力范围内的压力下将流体引入到较大的直径并且通过膨胀液撤出时的弹性反冲。可膨胀的远端部分在高于第一压力范围的压力下是相对不符合的。优选地，扩张导管具有可膨胀构件或球囊（16），该可膨胀构件或球囊（16）设置在可扩张远侧区段的远侧，该膨胀构件或球囊由与可膨胀远侧区段相同的聚合物材料形成并且与可扩展远端区段内的可扩张内腔流体连通。

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