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1. 发明申请

WO2010048190A3 ANTIBODIES THAT BIND TO IL-12 AND METHODS OF PURIFYING THE SAME 审中-公开
标题翻译：与IL-12结合的抗体及其纯化方法
公开(公告)号：WO2010048190A3
公开(公告)日：2010-06-17
申请号：PCT/US2009061335
申请日：2009-10-20
申请人： ABBOTT LAB , HICKMAN ROBERT K , HUANG QING , PERILLI-PALMER BARBARA
发明人： HICKMAN ROBERT K , HUANG QING , PERILLI-PALMER BARBARA
IPC分类号： C07K16/00
CPC分类号： C07K16/00
摘要： Anti-IL-12 antibodies are disclosed herein, including antigen-binding portions thereof. One or more methods for isolating and purifying anti-IL-12 antibodies from a sample matrix is presented. These isolated anti-IL-12 antibodies can be used in a clinical setting as well as in research and development. Pharmaceutical compositions comprising isolated anti-IL-12 antibodies are also described.
摘要翻译：本文公开了抗IL-12抗体，包括其抗原结合部分。介绍了一种或多种从样品基质中分离和纯化抗IL-12抗体的方法。这些分离的抗IL-12抗体可用于临床环境以及研究和开发。还描述了包含分离的抗IL-12抗体的药物组合物。

2. 发明专利

AU2021106952A4 Photoreceptor mounting base and lamp 未知
公开(公告)号：AU2021106952A4
公开(公告)日：2021-11-25
申请号：AU2021106952
申请日：2021-08-24
申请人： HUANG QING
发明人： HUANG QING
IPC分类号： F21V17/02
摘要： Embodiments of the present application relate to the technical field of lamps, and in particular, disclose a photoreceptor mounting base and a lamp. A photoreceptor mounting base includes a housing and a rotation member. The housing is provided with a receiving cavity and an opening that communicates with the receiving cavity. The rotation member is received in the receiving cavity and is rotatably connected to the housing. The rotation member is configured to mount a photoreceptor, and a part of the photoreceptor is exposed to the opening. By means of the preceding modes, the embodiments of the present application can implement: through the rotation of the rotation member, the rotation of the photoreceptor can be implemented; a photoreceptive lens disposed on an exposed part of the photoreceptor can rotate around an axis of the rotation member, so as to implement accurate induction of changing light rays outside by the photoreceptor.

3. 发明专利

NZ592094A ANTIBODIES THAT BIND TO IL-18 AND METHODS OF PURIFYING THE SAME 未知
公开(公告)号：NZ592094A
公开(公告)日：2013-01-25
申请号：NZ59209409
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： HICKMAN ROBERT K , HUANG QING , GERVAIS JOHANNA
IPC分类号： C07K16/06 , C07K16/24
摘要： Disclosed is a method for producing a host cell protein (HCP) reduced anti-interleukin-18 (IL-18) antibody, or antigen binding portion thereof, preparation from a sample mixture comprising an anti-IL-18 antibody, or antigen binding portion thereof, and at least one HCP, said method comprising: Subjecting said sample mixture to a reduction in pH thus forming a primary recovery sample, wherein said reduction in pH is between about 3.0 to about 4.0; Adjusting said primary recovery sample to a pH between about 4.5 to about 5.5 and a conductivity of approximately 9 mS per cm followed by; Applying said primary recovery sample to a cation exchange resin and collecting a cation exchange sample; and Applying said cation exchange sample to a hydrophobic interactive chromatography (HIC) resin and collecting an HIC sample, wherein said HIC sample comprises said HCP-reduced anti-IL-18 antibody, or antigen binding portion thereof, preparation.

4. 发明专利

MX2011004199A ANTICUERPOS QUE UNEN A IL-18 Y METODOS PARA PURIFICAR LOS MISMOS. 未知
公开(公告)号：MX2011004199A
公开(公告)日：2011-05-24
申请号：MX2011004199
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： HICKMAN ROBERT K , HUANG QING , GERVAIS JOHANNA
IPC分类号： C07K16/06 , C07K16/24
摘要： Se describen en la presente los anticuerpos anti-IL-18, incluyendo las porciones de unión a antígeno de los mismos. Se presentan uno o más métodos para aislar y purificar los anticuerpos anti-IL-18 a partir de una matriz de muestra. Estos anticuerpos anti-IL-18 aislados pueden utilizarse en un contexto clínico así como en la investigación y desarrollo. También se describen las composiciones farmacéuticas que comprenden los anticuerpos anti-IL-18 aislados.

5. 发明专利

CA2738498A1 ISOLATION AND PURIFICATION OF ANTIBODIES USING PROTEIN A AFFINITY CHROMATOGRAPHY 未知
公开(公告)号：CA2738498A1
公开(公告)日：2010-12-09
申请号：CA2738498
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： HICKMAN ROBERT K , HUANG QING , WEED CHERYL L , ENNIS SCOTT T , PERILLI-PALMER BARBARA , WAN MIN
IPC分类号： C07K16/00 , C07K16/24
摘要： Disclosed herein are methods for the isolation and purification of antibodies wherein the use of an affinity chromatographic step results in an antibody composition sufficiently pure for pharmaceutical uses. The methods described herein comprise pH viral reduction/inactivation, ultrafiltration/diafiltration, affinity chromatography, preferably Protein A affinity, ion exchange chromatography, and hydrophobic chromatography. Further, the present invention is directed toward pharmaceutical compositions comprising one or more antibodies of the present invention.

6. 发明专利

BRPI0919547A2 anticorpos que se ligam a il-12 e métodos de purificação do mesmo 未知
公开(公告)号：BRPI0919547A2
公开(公告)日：2015-12-08
申请号：BRPI0919547
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： PERILLI-PALMER BARBARA , HUANG QING , HICKMAN ROBERT K
IPC分类号： C07K16/00

7. 发明专利

SG195573A1 ANTIBODIES THAT BIND TO IL-12 AND METHODS OF PURIFYING THE SAME 未知
公开(公告)号：SG195573A1
公开(公告)日：2013-12-30
申请号：SG2013077813
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： HICKMAN ROBERT K , HUANG QING , PERILLI-PALMER BARBARA
摘要： 5 Anti-IL-12 antibodies are disclosed herein, including antigen-bindingportions thereof One or more methods for isolating and purifying anti-IL-12 antibodies from a sample matrix is presented. These isolated anti-IL-12 antibodies can be used in a clinical setting as well as in research and development.Pharmaceutical compositions comprising isolated anti-IL-12 antibodies are also 10 described.Figure 1

8. 发明专利

CA2739077A1 ANTIBODIES THAT BIND TO IL-18 AND METHODS OF PURIFYING THE SAME 未知
公开(公告)号：CA2739077A1
公开(公告)日：2010-04-29
申请号：CA2739077
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： HICKMAN ROBERT K , HUANG QING , GERVAIS JOHANNA
IPC分类号： C07K16/06 , C07K16/24
摘要： Anti-IL-18 antibodies are disclosed herein, including antigen-binding portions thereof. One or more methods for isolating and purifying anti-IL-18 antibodies from a sample matrix is presented. These isolated anti-IL-18 antibodies can be used in a clinical setting as well as in research and development. Pharmaceutical compositions comprising isolated anti-IL-18 antibodies are also described.

9. 发明专利

BRPI0920027A2 isolamento e purificação de anticorpos usando cromatografia de afinidade a proteína a 未知
公开(公告)号：BRPI0920027A2
公开(公告)日：2015-10-06
申请号：BRPI0920027
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： PERILLI-PALMER BARBARA , WEED CHERYL L , WAN MIN , HUANG QING , HICKMAN ROBERT K , ENNIS SCOTT T
IPC分类号： C07K16/00 , C07K16/24

10. 发明专利

AU2009347206A8 Isolation and purification of antibodies using Protein A affinity chromatography 未知
公开(公告)号：AU2009347206A8
公开(公告)日：2011-05-26
申请号：AU2009347206
申请日：2009-10-20
申请人： ABBOTT LAB
发明人： HICKMAN ROBERT K , HUANG QING , WEED CHERYL L , ENNIS SCOTT T , PERILLI-PALMER BARBARA , WAN MIN
IPC分类号： C07K16/00 , C07K16/24

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