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1. 发明申请

WO2010139451A3 OSTEOSYNTHESIS WITH NANO-SILVER 审中-公开
标题翻译：具有纳米银的氧化还原作用
公开(公告)号：WO2010139451A3
公开(公告)日：2011-05-26
申请号：PCT/EP2010003308
申请日：2010-06-01
申请人： AAP BIOMATERIALS GMBH , DINGELDEIN ELVIRA , GASQUERES CYRILLE , WITTE FRANK , ELIZIER AMIR
发明人： DINGELDEIN ELVIRA , GASQUERES CYRILLE , WITTE FRANK , ELIZIER AMIR
IPC分类号： A61L27/30 , A61L27/54 , C23C18/00 , C25D11/02
CPC分类号： C25D11/024 , A61L27/306 , A61L27/54 , A61L31/088 , A61L31/16 , A61L2300/102 , A61L2300/104 , A61L2300/606 , A61L2300/802 , A61L2400/12 , A61L2400/18 , A61L2420/06 , C25D11/005 , C25D11/022
摘要： The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO2 coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.
摘要翻译：本发明一般涉及一种由银组成的抗菌涂层，医用工具以及包含这种涂层的植入物以及制备这种涂层的方法。医疗工具或牙科或矫形植入物包括具有处理表面的金属或金属合金，其中经处理的表面至少部分地通过使用胶体分散系统的等离子体电解氧化转化为氧化膜，并且其中转换的表面被部分覆盖由胶体分散体系的胶体分散的银颗粒形成的岛。根据本发明的Ag-TiO 2涂层在抗菌功效（甚至针对多抗性菌株），粘附和生物相容性方面表现出优异的性质。植入物在人体内的寿命增加。抗菌涂层可用于创伤学，骨科，骨接合术和/或内切除术领域，特别是在存在高感染风险的地方。目前存在的大量医疗工具和植入物可以受益于这种涂层。

2. 发明专利

BRPI1013015A2 "osteosíntese com nanoprata" 未知
公开(公告)号：BRPI1013015A2
公开(公告)日：2016-03-29
申请号：BRPI1013015
申请日：2010-06-01
申请人： AAP BIOMATERIALS GMBH & CO KG
发明人： ELIZIER AMIR , GASQUERES CYRILLE , DINGELDEIN ELVIRA , WITTE FRANK
IPC分类号： C23C18/00 , A61L27/30 , A61L27/54 , C25D11/02

3. 发明专利

AU2010255982A1 Osteosynthesis with nano-silver 未知
公开(公告)号：AU2010255982A1
公开(公告)日：2012-01-19
申请号：AU2010255982
申请日：2010-06-01
申请人： AAP BIOMATERIALS GMBH
发明人： DINGELDEIN ELVIRA , GASQUERES CYRILLE , WITTE FRANK , ELIZIER AMIR
IPC分类号： A61L27/30 , A61L27/54 , C23C18/00 , C25D11/02
摘要： The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.

4. 发明专利

CA2763946C OSTEOSYNTHESIS WITH NANO-SILVER 未知
公开(公告)号：CA2763946C
公开(公告)日：2018-08-21
申请号：CA2763946
申请日：2010-06-01
申请人： AAP BIOMATERIALS GMBH
发明人： DINGELDEIN ELVIRA , GASQUERES CYRILLE , WITTE FRANK , ELIZIER AMIR
IPC分类号： A61L27/30 , A61L27/54 , C23C18/00 , C25D11/02
摘要： The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO2 coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.

5. 发明专利

CA2763946A1 OSTEOSYNTHESIS WITH NANO-SILVER 未知
公开(公告)号：CA2763946A1
公开(公告)日：2010-12-09
申请号：CA2763946
申请日：2010-06-01
申请人： AAP BIOMATERIALS GMBH
发明人： DINGELDEIN ELVIRA , GASQUERES CYRILLE , WITTE FRANK , ELIZIER AMIR
IPC分类号： A61L27/30 , A61L27/54 , C23C18/00 , C25D11/02
摘要： The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag-TiO2 coating according to the invention shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists. A high number of currently existing medical tools and implants can benefit from such a coating.

6. 发明专利

DE102009023459A1 Osteosynthese mit Nanosilber 未知
公开(公告)号：DE102009023459A1
公开(公告)日：2010-12-09
申请号：DE102009023459
申请日：2009-06-02
申请人： AAP BIOMATERIALS GMBH
发明人： GASQUERES CYRILLE , ELIEZER AMIR , DINGELDEIN ELVIRA , WITTE FRANK
IPC分类号： A61L27/54 , A61L27/04 , A61L31/08
摘要： Die vorliegende Erfindung bezieht sich allgemein auf eine antibakterielle Beschichtung, die aus Silber aufgebaut ist, auf medizinische Werkzeuge und auf Implantate, welche solch eine Beschichtung umfassen, und auf ein Verfahren als auch auf eine Vorrichtung zur Herstellung einer solchen Beschichtung. Die medizinischen Werkzeuge oder die dentalen oder orthopädischen Implantate umfassen ein Metall oder eine Metalllegierung mit einer behandelten Oberfläche, wobei die behandelte Oberfläche zumindest teilweise in eine Oxidschicht konvertiert bzw. umgewandelt ist durch eine Plasma-elektrolytische Oxidation unter Verwendung eines Kolloid-dispersen Systems und wobei die konvertierte Oberfläche zumindest teilweise bedeckt ist mit Inseln, die gebildet sind durch Kolloid-dispergierte Silberteilchen des Kolloid-dispersen Systems. Eine erfindungsgemäße Ag-TiO-Beschichtung zeigt exzellente Eigenschaften im Hinblick auf antibakterielle Wirksamkeit (sogar gegenüber multiresistenten Bakterienstämmen), Adhäsion und Biokompatibilität. Die Lebenszeit eines Implantats in einem menschlichen Körper wird erhöht. Die antibakterielle Beschichtung kann verwendet werden in dem Gebiet der Traumatologie, der Orthopädie, der Osteosynthese und/oder der Endoprothetik, insbesondere dort, wo ein hohes Infektionsrisiko existiert. Eine große Anzahl an derzeit bestehenden medizinischen Werkzeugen und Implantaten kann von einer solchen Beschichtung profitieren.

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