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1. 发明申请

WO2008086137A1 DEVICE FOR THE QUALIFICATION OF COOKING OILS, AND METHODS 审中-公开
标题翻译：烹饪油鉴定装置及方法
公开(公告)号：WO2008086137A1
公开(公告)日：2008-07-17
申请号：PCT/US2008/050172
申请日：2008-01-04
申请人： 3M INNOVATIVE PROPERTIES COMPANY , WEI, Ai-Ping , RAJAGOPAL, Raj, , BINEAU, Catherine
发明人： WEI, Ai-Ping , RAJAGOPAL, Raj, , BINEAU, Catherine
IPC分类号： G01N33/26 , G01N33/52
CPC分类号： G01N33/03 , G01N21/6428 , G01N21/645 , G01N2201/0221 , G01N2201/0245
摘要： A method of determining the quality of oil by irradiating the oil at a first wavelength, e.g., of about 470 nm, measuring a level of fluorescence of the oil at a second wavelength, e.g., of about 520 nm, comparing the measured fluorescence level to a predetermined threshold level to determine whether or not the oil quality is acceptable. The oil is preferably discarded if the measured fluorescence level exceeds the predetermined threshold level, which can be generally dependent on the oil composition. The fluorescence is correlated to the level of polar components in the oil. Also described are devices for determining the quality of oil via fluorescence.
摘要翻译：通过以例如约470nm的第一波长（例如约470nm）照射油来测定油的质量的方法，测量在第二波长例如约520nm的油的荧光水平，将测量的荧光水平与预定的阈值水平以确定油品质量是否可接受。如果测量的荧光水平超过预定阈值水平，则油优选地被丢弃，其通常可以取决于油组成。荧光与油中极性组分的水平相关。还描述了用于通过荧光确定油质量的装置。

2. 发明申请

WO2009111370A2 MONITORING OF FRYING OIL QUALITY USING COMBINED OPTICAL INTERROGATION METHODS AND DEVICES 审中-公开
标题翻译：使用组合光学方法和装置监测油脂质量
公开(公告)号：WO2009111370A2
公开(公告)日：2009-09-11
申请号：PCT/US2009/035645
申请日：2009-03-02
申请人： 3M INNOVATIVE PROPERTIES COMPANY , WEI, Ai-Ping , SABADE, Milind, B. , MAHMOODI, Abolghassem B.
发明人： WEI, Ai-Ping , SABADE, Milind, B. , MAHMOODI, Abolghassem B.
IPC分类号： G01N33/03
CPC分类号： G01N33/03 , G01N21/643 , G01N21/78 , G01N31/22
摘要： Herein are disclosed methods and devices for optically monitoring multiple parameters of an oil sample. In one embodiment, the methods and devices can be used for determining the quality of cooking or frying oil in terms of the free fatty acid content and total polar compound content of the oil. The methods use an optical absorbtive/reflective property in evaluating the free fatty acid content, and use optical fluorescence in evaluating the total polar compound content, with both measurements using a single sampling substrate and a single measuring device.
摘要翻译：本文公开了用于光学监测油样品的多个参数的方法和装置。在一个实施方案中，所述方法和装置可以用于根据游离脂肪酸含量和油的总极性化合物含量来确定烹饪或煎炸油的质量。该方法在评估游离脂肪酸含量时使用光学吸收/反射性质，并且使用光学荧光来评估总极性化合物含量，两次测量使用单个采样衬底和单个测量装置。

3. 发明申请

WO2010045433A1 STERILITY INDICATING BIOLOGICAL COMPOSITIONS, ARTICLES AND METHODS 审中-公开
标题翻译：表明生物组成的无效性，文章和方法
公开(公告)号：WO2010045433A1
公开(公告)日：2010-04-22
申请号：PCT/US2009/060805
申请日：2009-10-15
申请人： 3M INNOVATIVE PROPERTIES COMPANY , CHANDRAPATI, Sailaja , WEBB, Heather, M. , WEI, Ai-Ping
发明人： CHANDRAPATI, Sailaja , WEBB, Heather, M. , WEI, Ai-Ping
IPC分类号： A61L2/28 , C12Q1/18 , C12M1/40
CPC分类号： C12Q1/37 , A61L2/28 , C12Q1/22
摘要： A sterility indicating composition comprising a plurality of sterilization process resistant spores which contain an active protease during germination and initial outgrowth of the spores; and a germination medium comprising at least one labeled protease substrate and at least one nutrient for germination of the spores; wherein the medium is essentially free of a) any active protease other than the active protease contained by the plurality of spores and b) any protease substrate other than the at least one labeled protease substrate, other than any protease substrate originating from the plurality of spores, and other than any protease substrate which does not compete with the labeled protease substrate for the active protease; and wherein the at least one labeled protease substrate comprises a peptide which can be cleaved by the active protease and which is labeled with one or more dye groups, at least one of which undergoes a detectable change when the peptide is cleaved by the active protease, and wherein the labeled protease substrate is stable at least at a temperature for incubating the spores, a sterilization process indicator comprising the composition, and a method of determining the effectiveness of a sterilization process using the composition and indicator are disclosed.
摘要翻译：一种不育指示组合物，其包含多个灭菌过程抗性孢子，其在萌发期间含有活性蛋白酶和孢子的初始产生; 以及包含至少一种标记的蛋白酶底物和至少一种用于孢子发芽的营养物的发芽培养基; 其中所述培养基基本上不含a）除所述多个孢子所含的活性蛋白酶以外的任何活性蛋白酶，和b）除所述至少一个标记的蛋白酶底物之外的任何蛋白酶底物，而不是源于所述多个孢子的任何蛋白酶底物，而不是与活性蛋白酶的标记的蛋白酶底物竞争的任何蛋白酶底物以外的其它蛋白酶底物; 并且其中所述至少一个标记的蛋白酶底物包含可被活性蛋白酶切割并且被一个或多个染料基团标记的肽，当肽被活性蛋白酶切割时，其中的至少一种经历可检测的变化，并且其中标记的蛋白酶底物至少在培养孢子的温度下是稳定的，包括该组合物的灭菌过程指示剂以及使用该组合物和指示剂确定灭菌过程的有效性的方法。

4. 发明公开

EP2104854A1 DEVICE FOR THE QUALIFICATION OF COOKING OILS, AND METHODS 审中-公开
标题翻译：设备技术分类食用油和程序
公开(公告)号：EP2104854A1
公开(公告)日：2009-09-30
申请号：EP08713489.6
申请日：2008-01-04
申请人： 3M Innovative Properties Company
发明人： WEI, Ai-Ping , RAJAGOPAL, Raj, , BINEAU, Catherine
IPC分类号： G01N33/26 , G01N33/52
CPC分类号： G01N33/03 , G01N21/6428 , G01N21/645 , G01N2201/0221 , G01N2201/0245
摘要： A method of determining the quality of oil by irradiating the oil at a first wavelength, e.g., of about 470 nm, measuring a level of fluorescence of the oil at a second wavelength, e.g., of about 520 nm, comparing the measured fluorescence level to a predetermined threshold level to determine whether or not the oil quality is acceptable. The oil is preferably discarded if the measured fluorescence level exceeds the predetermined threshold level, which can be generally dependent on the oil composition. The fluorescence is correlated to the level of polar components in the oil. Also described are devices for determining the quality of oil via fluorescence.

5. 发明公开

EP2346534A1 STERILITY INDICATING BIOLOGICAL COMPOSITIONS, ARTICLES AND METHODS 审中-公开
标题翻译： STERILITÄTSANZEIGENDE的生物组合物，制品和方法
公开(公告)号：EP2346534A1
公开(公告)日：2011-07-27
申请号：EP09748882.9
申请日：2009-10-15
申请人： 3M Innovative Properties Company
发明人： CHANDRAPATI, Sailaja , WEBB, Heather, M. , WEI, Ai-Ping
IPC分类号： A61L2/28 , C12Q1/18 , C12M1/40
CPC分类号： C12Q1/37 , A61L2/28 , C12Q1/22
摘要： A sterility indicating composition comprising a plurality of sterilization process resistant spores which contain an active protease during germination and initial outgrowth of the spores; and a germination medium comprising at least one labeled protease substrate and at least one nutrient for germination of the spores; wherein the medium is essentially free of a) any active protease other than the active protease contained by the plurality of spores and b) any protease substrate other than the at least one labeled protease substrate, other than any protease substrate originating from the plurality of spores, and other than any protease substrate which does not compete with the labeled protease substrate for the active protease; and wherein the at least one labeled protease substrate comprises a peptide which can be cleaved by the active protease and which is labeled with one or more dye groups, at least one of which undergoes a detectable change when the peptide is cleaved by the active protease, and wherein the labeled protease substrate is stable at least at a temperature for incubating the spores, a sterilization process indicator comprising the composition, and a method of determining the effectiveness of a sterilization process using the composition and indicator are disclosed.

6. 发明公开

EP2260299A2 MONITORING OF FRYING OIL QUALITY USING COMBINED OPTICAL INTERROGATION METHODS AND DEVICES 审中-公开
标题翻译：用于使用光学研究的组合监测炸油质量的方法和装置
公开(公告)号：EP2260299A2
公开(公告)日：2010-12-15
申请号：EP09716484.2
申请日：2009-03-02
申请人： 3M Innovative Properties Company
发明人： WEI, Ai-Ping , SABADE, Milind, B. , MAHMOODI, Abolghassem B.
IPC分类号： G01N33/03 , G01N33/26 , G01N21/80 , G01N21/64
CPC分类号： G01N33/03 , G01N21/643 , G01N21/78 , G01N31/22
摘要： Herein are disclosed methods and devices for optically monitoring multiple parameters of an oil sample. In one embodiment, the methods and devices can be used for determining the quality of cooking or frying oil in terms of the free fatty acid content and total polar compound content of the oil. The methods use an optical absorbtive/reflective property in evaluating the free fatty acid content, and use optical fluorescence in evaluating the total polar compound content, with both measurements using a single sampling substrate and a single measuring device.

7. 发明授权

EP1228147B1 DYE LABELED IMIDAZOQUINOLINE COMPOUNDS 有权
标题翻译：染料标记的咪唑并喹啉
公开(公告)号：EP1228147B1
公开(公告)日：2004-02-04
申请号：EP00980282.8
申请日：2000-11-03
申请人： 3M Innovative Properties Company
发明人： WEI, Ai-Ping , TOMAI, Mark, A. , RICE, Michael, J.
IPC分类号： C09B11/08 , C09B57/00 , C09B69/00 , G01N33/94 , C07D471/14
CPC分类号： C07D471/04 , C09B11/08 , C09B57/10 , C09B69/00 , G01N33/6863
摘要： Dye labeled imidazonaphthyridine, imidazopyridine and imidazoquinoline compounds having immune response modulating activity are disclosed. The compounds are useful, inter alia, for determining the binding and/or receptor sites of the molecules.

8. 发明公开

EP1228147A1 DYE LABELED IMIDAZOQUINOLINE COMPOUNDS 有权
标题翻译：染料标记的咪唑并喹啉
公开(公告)号：EP1228147A1
公开(公告)日：2002-08-07
申请号：EP00980282.8
申请日：2000-11-03
申请人： 3M Innovative Properties Company
发明人： WEI, Ai-Ping , TOMAI, Mark, A. , RICE, Michael, J.
IPC分类号： C09B11/08 , C09B57/00 , C09B69/00 , G01N33/94 , C07D471/14
CPC分类号： C07D471/04 , C09B11/08 , C09B57/10 , C09B69/00 , G01N33/6863
摘要： Dye labeled imidazonaphthyridine, imidazopyridine and imidazoquinoline compounds having immune response modulating activity are disclosed. The compounds are useful, inter alia, for determining the binding and/or receptor sites of the molecules.

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