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1. 发明申请

WO2007124406A3 DOSE COUNTER 审中-公开
公开(公告)号：WO2007124406A3
公开(公告)日：2007-11-01
申请号：PCT/US2007/067056
申请日：2007-04-20
申请人： 3M INNOVATIVE PROPERTIES COMPANY , STUART, Adam J. , PURKINS, Graham R. , STREIBIG, Rachel , HOWGILL, Stephen J. , HODSON, Peter D. , BREWER, Richard D. , HOLDEN, Benjamin J.
发明人： STUART, Adam J. , PURKINS, Graham R. , STREIBIG, Rachel , HOWGILL, Stephen J. , HODSON, Peter D. , BREWER, Richard D. , HOLDEN, Benjamin J.
IPC分类号： A61J7/02 , A61J7/00 , A61J7/04
摘要： This application discloses a dose counter for use in connection with a device adapted for metered dispensing of a medication. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.

2. 发明申请

WO2013188609A1 METERED DOSE DISPENSING VALVE 审中-公开
标题翻译：计量剂量分配阀
公开(公告)号：WO2013188609A1
公开(公告)日：2013-12-19
申请号：PCT/US2013/045549
申请日：2013-06-13
申请人： 3M INNOVATIVE PROPERTIES COMPANY , STUART, Adam J. , HODSON, Peter D. , HOWGILL, Stephen J. , OAKLEY, Matthew A. , GREENLEAF, David J.
发明人： STUART, Adam J. , HODSON, Peter D. , HOWGILL, Stephen J. , OAKLEY, Matthew A. , GREENLEAF, David J.
IPC分类号： A61M15/00
CPC分类号： A61M15/009 , A61M15/0071 , B05B11/3077 , B65D83/30 , B65D83/54 , F16F1/028 , G01F11/006 , G01F11/025 , G01F11/12 , G01F11/16
摘要： The present disclosure relates to a metered dose dispensing valve for dispensing metered volumes of an aerosol formulation from an aerosol container. The valves described herein are particularly suitable for use with metered dose inhalers for the oral delivery of medicaments. By combining the compliant biasing member and the second valve body into an integral single component it is possible to provide a desirable metered dose dispensing valve for use in inhalation devices or for use in the provision of canisters targeted for use in inhalation devices.
摘要翻译：本公开涉及一种用于从气溶胶容器分配计量体积的气溶胶制剂的计量剂量分配阀。本文所述的阀特别适用于用于口服递送药物的计量吸入器。通过将柔性偏压构件和第二阀体组合成一体的单个部件，可以提供用于吸入装置的期望的计量剂量分配阀或用于提供目标用于吸入装置的罐。

3. 发明公开

EP4142837A1 COVER ASSEMBLY AND ACTUATOR FOR INHALER 有权转让
公开(公告)号：EP4142837A1
公开(公告)日：2023-03-08
申请号：EP21725922.5
申请日：2021-04-26
申请人： Kindeva Drug Delivery L.P. , Hodson, Peter D. , Stuart, Adam J.
发明人： HODSON, Peter D. , STUART, Adam J.
IPC分类号： A61M15/00 , B65D41/00 , B65D55/16 , B65D47/14

4. 发明申请

WO2011063067A1 DOSE COUNTER 审中-公开
标题翻译：剂量计数器
公开(公告)号：WO2011063067A1
公开(公告)日：2011-05-26
申请号：PCT/US2010/057135
申请日：2010-11-18
申请人： 3M INNOVATIVE PROPERTIES COMPANY , STUART, Adam J.
发明人： STUART, Adam J.
IPC分类号： G06M1/24 , G06M1/16 , A61M5/00
CPC分类号： A61M15/009 , A61M15/0073 , A61M15/0075 , G06M1/041 , G06M1/24
摘要： Described are a dose counter (200) for use with an inhaler (5), and an actuator (20) for use with or as part of a dispenser. Further described is a dispenser containing a dose counter.
摘要翻译：描述了与吸入器（5）一起使用的剂量计数器（200）以及用于或作为分配器的一部分的致动器（20）。进一步描述的是包含剂量计数器的分配器。

5. 发明申请

WO2011133740A1 DRY POWDER INHALER ASSEMBLY AND CONTAINERS 审中-公开
标题翻译：干粉收集器和集装箱
公开(公告)号：WO2011133740A1
公开(公告)日：2011-10-27
申请号：PCT/US2011/033373
申请日：2011-04-21
申请人： CAMBRIDGE CONSULTANTS LIMITED , HARRIS, David S. , ALLEN, Matthew D. , FULLER, Amanda J. , HARRISON, Nicholas , HEWSON, Karl J. , HODSON, Peter D. , LEWIS, Scott A. , OAKLEY, Tom A. , PATTERSON, Samantha A. , SMITH, Simon J. , STRIEBIG, Rachel V. , STUART, Adam J. , MERRILL, Bryon A.
发明人： HARRIS, David S. , ALLEN, Matthew D. , FULLER, Amanda J. , HARRISON, Nicholas , HEWSON, Karl J. , HODSON, Peter D. , LEWIS, Scott A. , OAKLEY, Tom A. , PATTERSON, Samantha A. , SMITH, Simon J. , STRIEBIG, Rachel V. , STUART, Adam J. , MERRILL, Bryon A.
IPC分类号： A61M15/00 , A61M11/00
CPC分类号： A61M15/0028 , A61M15/0021 , A61M15/0026 , A61M15/0036 , A61M15/0041 , A61M15/0043 , A61M2202/064 , A61M2205/6045 , A61M2206/16
摘要： The present disclosure provides dry powder inhalers, containers for carrying a dose of dry powder medicament particles for dry powder inhalers, and a hinge that, while enjoying broader applicability, may be used in such inhalers.
摘要翻译：本公开提供干粉吸入器，用于携带用于干粉吸入器的干粉药物颗粒剂量的容器，以及在这种吸入器中可以使用更广泛适用性的铰链。

6. 发明申请

WO2021222087A1 COVER ASSEMBLY AND ACTUATOR FOR INHALER 审中-公开
公开(公告)号：WO2021222087A1
公开(公告)日：2021-11-04
申请号：PCT/US2021/029125
申请日：2021-04-26
申请人： KINDEVA DRUG DELIVERY L.P. , HODSON, Peter D. , STUART, Adam J.
发明人： HODSON, Peter D. , STUART, Adam J.
IPC分类号： A61M15/00 , B65D41/00 , B65D55/16 , B65D47/14
摘要： An actuator (100) for an inhaler includes a sleeve (106) having a first end (102) and a second end (104). The sleeve is substantially hollow and defines a longitudinal axis (110) along its length. A base (108) is formed at the first end of the sleeve. A mouthpiece (112) is joined to the sleeve and the base. The mouthpiece is substantially hollow and defines a delivery opening (114). The actuator includes a cover (116) removably attached to the mouthpiece for covering the delivery opening. The actuator further includes a retaining member for retaining the cover to the sleeve upon removal of the cover from the mouthpiece. The retaining member includes a ring (120) disposed around the sleeve. The ring is at least selectively rotatable about the longitudinal axis and slidable along the longitudinal axis relative to the sleeve. The retaining member further includes a strap (122) extending from the ring and attached to the cover.

7. 发明申请

WO2014186263A2 ACTUATOR FOR AN INHALER 审中-公开
标题翻译：吸入器的执行器
公开(公告)号：WO2014186263A2
公开(公告)日：2014-11-20
申请号：PCT/US2014/037649
申请日：2014-05-12
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： BREWER, Richard D. , STUART, Adam J. , GRIFFITHS, Neale F.
IPC分类号： A61M15/00
CPC分类号： A61M15/0025 , A61M15/0026 , A61M15/0071 , A61M15/0075 , A61M15/009 , A61M15/08 , A61M2207/00
摘要： An actuator for an inhaler, in particular a nasal actuator, is disclosed, the actuator comprising a body, a stem post and fixing means for fixing the stem post in the body. The body comprises a delivery passage for delivery of a medicament and a canister opening for insertion of a canister having a metering valve with a valve stem. The stem post comprises a stem socket for receiving the valve stem of a canister and comprises an orifice for discharging a medicament to the delivery passage. The stem post and body are adapted so they cooperate to define a transition chamber when the stem post is fixed in the body. Also disclosed is a method of forming an component for an actuator for an inhaler, and a method of assembling an actuator for an inhaler by inserting the stem post through the canister opening and into the body thereby.
摘要翻译：公开了一种用于吸入器，特别是鼻部致动器的致动器，致动器包括主体，杆柱和用于将杆柱固定在身体中的固定装置。主体包括用于输送药物的输送通道和用于插入具有带阀杆的计量阀的罐的罐开口。杆柱包括用于容纳罐的阀杆的杆插座，并且包括用于将药物排放到输送通道的孔口。杆柱和主体适于使得当杆柱固定在身体中时它们协作以限定过渡室。还公开了一种形成用于吸入器的致动器的部件的方法，以及通过将杆柱插入通过罐开口并进入本体而组装用于吸入器的致动器的方法。

8. 发明申请

WO2020141424A1 INHALER DETECTION 审中-公开
公开(公告)号：WO2020141424A1
公开(公告)日：2020-07-09
申请号：PCT/IB2019/061415
申请日：2019-12-27
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： HODSON, Peter D. , MOHAMMED, Parfes , STUART, Adam J. , JOLLY, Paul H. R.
IPC分类号： A61M15/00 , A61M11/00 , A61M16/00
摘要： An inhaler having an air inlet, a medicament source, and an outlet for delivering an air and medicament admixture to a user, the inhaler including a primary power supply for powering the controller and a sensor for detecting a recent shake event, wherein, the sensor is independent of the primary power source and, in use, the sensor provides the controller with a signal indicative of any recent shake event upon the powering up of the controller prior to use of the inhaler.

9. 发明申请

WO2018048797A1 TRIGGER MECHANISM FOR AN INHALER 审中-公开
标题翻译：吸入器的触发机制
公开(公告)号：WO2018048797A1
公开(公告)日：2018-03-15
申请号：PCT/US2017/050067
申请日：2017-09-05
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： STUART, Adam J. , HODSON, Peter D.
IPC分类号： A61M15/00 , A61M15/06
摘要： A breath-responsive inhaler having a trigger mechanism for triggering delivery of a medicament to a user, the trigger mechanism including a medicament source, having a primed position in which the inhaler is primed for use and an actuated position in which the medicament source is actuated to dispense a dose of medicament, a toggle mechanism for selectively permitting movement of the source from its primed position to its actuated position, the toggle mechanism comprising a vane positioned in the air flow path, the vane being pivoted about a vane pivot, and wherein the trigger mechanism is triggered by movement of the vane upon inhalation of the user to move the toggle mechanism between a primed condition in which the medicament source is maintained in its primed position by cooperation with the toggle mechanism and an actuated condition in which the toggle mechanism is disengaged from cooperation with the medicament source
摘要翻译：呼吸响应吸入器，其具有用于触发药剂输送给使用者的触发器机构，所述触发器机构包括药剂源，所述药剂源具有吸入器准备好使用的准备好的位置和致动的在其中致动药剂源以分配一剂药物的位置;肘节机构，用于选择性地允许源从其准备好的位置运动到其致动位置，肘节机构包括定位在空气流动路径中的叶片，叶片是并且其中所述触发机构通过在吸入所述使用者时所述叶片的移动而触发，以在所述药剂源通过与所述肘节机构协作而保持在其准备好的位置的起动状态之间移动所述肘节机构，以及其中肘节机构脱离与药物源的协作的致动状态

10. 发明申请

WO2017087368A1 IMPROVEMENTS IN METERED DOSE INHALER DEVICES 审中-公开
标题翻译：测量剂量吸入器装置的改进
公开(公告)号：WO2017087368A1
公开(公告)日：2017-05-26
申请号：PCT/US2016/062000
申请日：2016-11-15
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： HODSON, Peter D. , STUART, Adam J.
IPC分类号： A61M15/00
CPC分类号： A61M15/009 , A61M15/0021 , A61M2205/586
摘要： Described herein is an actuator housing (500) for use with a metered dose inhaler (MDI) device which comprises a housing portion (115) having a nozzle block in which an actuator seat and an actuator nozzle are formed, and a mouthpiece portion (525) joined to the housing portion (115). The mouthpiece portion (525) has an external surface having a first or guidance region (570) over which teeth of a patient are to be located and a second or sealing region (580) against which lips of the patient seal during dispensing of a medicament. In one embodiment, the first or guidance region (570) comprises a plurality of longitudinally extending flutes arranged around the external surface and located adjacent to a mouthpiece end face (560). An optional annular projection (590) may be provided to define more precisely the sealing region for the patient.
摘要翻译：这里描述的是与定量吸入器（MDI）装置一起使用的致动器壳体（500），其包括具有喷嘴块的壳体部分（115），在该喷嘴块中，致动器座和致动器喷嘴是以及接合到壳体部分（115）的接口部分（525）。吸嘴部分（525）具有外表面和第二或密封区域（580），所述外表面具有第一或引导区域（570），患者的牙齿将定位在第一或引导区域（570）上，在分配药物期间，患者的唇部密封。在一个实施例中，第一或引导区域（570）包括围绕外表面布置并且邻近吹口端面（560）定位的多个纵向延伸的凹槽。可以提供可选的环形突起（590）以更精确地限定患者的密封区域。

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