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    • 7. 发明申请
    • METHOD OF STERILIZATION OF WOUND DRESSINGS
    • 绕线条的灭菌方法
    • WO2011119393A2
    • 2011-09-29
    • PCT/US2011/028660
    • 2011-03-16
    • 3M INNOVATIVE PROPERTIES COMPANY
    • HOLM, David R.
    • A61L2/08A61F13/00A61L15/22A61L15/28B65B55/08
    • A61F13/00991A61F13/00042A61F2013/00314A61F2013/00748A61L2/087C08J3/28C08J7/02C08J2353/02
    • Methods of sterilizing articles such as wound dressings, include the steps of providing an article that includes a polymer layer, applying an aqueous solution to the polymer layer and applying electron beam radiation to the article. The polymer layer includes a hydrophobic organic matrix that includes an elastomeric polymer and hydrophilic polymeric microparticles dispersed within the elastomeric polymer. Applying the aqueous solution to the polymer layer at least partially swells the hydrophilic microparticles of the polymer layer. In some articles the polymer layer includes an elastomeric polymer, hydrophilic polymeric microparticles dispersed within the elastomeric polymer, and hydrophilic polymer particles with greater than 10 micrometers average particle size dispersed within the hydrophobic organic matrix. These articles may be sterilized by applying either electron beam or gamma radiation.
    • 对诸如伤口敷料的物品进行灭菌的方法包括提供包括聚合物层的制品的步骤,向聚合物层施加水溶液并向制品施加电子束辐射。 聚合物层包括疏水性有机基质,其包括分散在弹性体聚合物内的弹性体聚合物和亲水性聚合物微粒。 将水溶液施加到聚合物层至少部分地膨胀聚合物层的亲水性微粒。 在一些制品中,聚合物层包括弹性体聚合物,分散在弹性体聚合物内的亲水性聚合物微粒和分散在疏水性有机基质中的平均粒径大于10微米的亲水聚合物颗粒。 这些物品可以通过施加电子束或γ辐射来灭菌。