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    • 1. 发明授权
    • 천연 휴믹 물질로부터 다기능성 추출물 제조방법
    • 自然人体材料多功能提取物的制备方法
    • KR101340597B1
    • 2013-12-11
    • KR1020130064560
    • 2013-06-05
    • 허교손지영
    • 허교손지영
    • C05D9/00C05F11/00
    • C05F11/00C05D9/00C05G1/00
    • The present invention relates to a method for manufacturing multi-functional extracts from natural humic substances. The present invention provides the method for manufacturing extracts which is transparent and yellow and has wavelength of maximum absorbance in a 260-280 nm range of ultraviolet by adding purified water so that the concentration of the natural humic substances can be 5-10wt% and obtaining supernatant using a centrifugal separator after stirring for 3-6 hours. The simple, low cost, and chemically safer extraction method is suggested by using purified water and extracts of grape fruit or lemon skin in order to overcome limitation of existing extraction methods which are inappropriate for practically utilizing active elements due to increase of expanse, inconvenience of going through several steps of extraction processes, and chemistry safety issues caused by using strong acids and strong bases. In addition, the extracts manufactured by the present invention has various and enhanced physiological activities such as plant growth promotion effects, plant pathological effects, deodorization effects, water purification effects, antibacterial effects, anti-allergic effects, liver function recovery effects, and cytotoxicity prevention effects. [Reference numerals] (AA) Natural humic substances;(BB) Purified water;(CC) 5-10% of raw material among purified water;(DD) Stir in warm water;(EE) Cooling;(FF) Centrifugation;(GG) Filtering;(HH) Natural humic substance extract
    • 本发明涉及从天然腐殖质制造多功能提取物的方法。 本发明提供透明黄色提取物的方法,通过加入纯水使260-280nm紫外线具有最大吸光度的波长,使得天然腐殖质的浓度可以达到5-10重量%,得到 上清液,搅拌3-6小时后,用离心分离机。 建议使用纯净水和葡萄水果或柠檬皮提取物的简单,低成本和化学更安全的提取方法,以克服现有的提取方法的限制,这些方法不适合实际使用活性成分,因为这种方法的扩大,不便 通过萃取过程的几个步骤,以及使用强酸和强碱引起的化学安全问题。 此外,本发明提取的提取物具有各种增强的生理活性,如植物生长促进作用,植物病理作用,除臭效果,水净化效果,抗菌作用,抗过敏作用,肝功能恢复作用和细胞毒性预防 效果。 (AA)天然腐殖质;(BB)净化水;(CC)净化水中5-10%的原料;(DD)在温水中搅拌;(EE)冷却;(FF)离心;( GG)过滤;(HH)天然腐殖质提取物
    • 3. 发明公开
    • 천연 휴믹 물질로 부터 휴믹산과 풀빅산 추출방법
    • 从人体物质中获得的酸性和酸性物质的渗透方法
    • KR1020120108816A
    • 2012-10-05
    • KR1020110027154
    • 2011-03-25
    • 허교손지영
    • 허교손지영
    • C07G99/00C07B63/00B01D11/02B01D37/00
    • C08H6/00B01D11/0292B01D21/26B01D2325/02
    • PURPOSE: A humic acid and fulvic acid sampling method from a natural humic substance is provided to obtain humic acid and fulvic acid in the high efficiency and high purity. CONSTITUTION: A humic acid and fulvic acid sampling method from a natural humic substance comprises the following steps: mixing the natural humic substance with a NaOH aqueous solution for the alkali extraction, and removing insoluble materials from the mixture to obtain a solution; adding hydrochloric acid into the solution until the pH of the mixture of 1.5, and centrifugal separating the mixture to obtain the precipitate; and washing the precipitate with a mixture of the hydrochloric acid and hydrofluoric acid.
    • 目的:提供从天然腐殖质获得的腐殖酸和富里酸采样方法,以高效率和高纯度获得腐殖酸和富里酸。 构成:天然腐殖质的腐殖酸和富里酸采样方法包括以下步骤:将天然腐殖质与NaOH水溶液混合进行碱萃取,并从混合物中除去不溶物,得到溶液; 向溶液中加入盐酸直到混合物的pH为1.5,离心分离得到沉淀物; 并用盐酸和氢氟酸的混合物洗涤沉淀物。
    • 4. 发明公开
    • 풀빅산의 탈취효과
    • 氟酸的去除效果
    • KR1020120108814A
    • 2012-10-05
    • KR1020110027152
    • 2011-03-25
    • 허교손지영
    • 허교손지영장경수나동희
    • A61L9/01
    • A61L9/01A61L2209/21
    • PURPOSE: A deodorization composition is provided to measure the concentration of ammonia, methylmercaptan, hydrogen sulfide, isovaleric acid, and propionic acid. CONSTITUTION: A deodorization composition includes fulvic acid as an active component. The fulvic acid removes 95% or more propionic acid, 87.5% or more methylmercaptan, 94% or more invalerate, 98% or more ammonia, and 50% or more hydrogen sulfoxide. The fulvic acid has improved profitability, availability, safety, and effectivity. [Reference numerals] (AA) Fermentation tank; (BB,CC,DD) Stirrer; (EE) Entrance
    • 目的:提供除臭组合物以测量氨,甲硫醇,硫化氢,异戊酸和丙酸的浓度。 构成:除臭组合物包括作为活性组分的富里酸。 该黄腐酸可除去95%以上的丙酸,87.5%以上的甲硫醇,94%以上的无水异氰酸酯,98%以上的氨,50%以上的氢亚砜。 富里酸提高了利润率,可用性,安全性和有效性。 (附图标记)(AA)发酵罐; (BB,CC,DD)搅拌器; (EE)入口
    • 5. 发明公开
    • 활성성분으로 풀빅산을 포함하는 항알러지 조성물
    • 用于将包含作为活性组分的氟化物的过敏的组合物
    • KR1020120108801A
    • 2012-10-05
    • KR1020110027131
    • 2011-03-25
    • 허교손지영
    • 허교손지영장경수나동희
    • A61K31/353A61K31/352A61P27/14
    • PURPOSE: An anti-allergic composition containing fulvic acid is provided to suppress the secretion of various allergic materials and to ensure excellent anti-allergic effect. CONSTITUTION: An anti-allergic composition contains fulvic acid as an active ingredient. Fulvic acid suppresses the secretion of allergic materials from mast cells causing allergy. The mast cells are RBL-2H3 cells. A method for preparing the mast cell RBL-2H3 comprises: a step of culturing mast cells in a medium containing glutamine, antibiotics, and 10% FBS; a step of collecting the mast cells by trypsin and culturing the mast cells with 200 ng/mL DNP-specific IgE; a step of washing the mast cells with PIPES buffer solution(25 mM PIPES, pH 7.2, 119 mM NaCl, 5 mM KCl, 0.4 mM MgCl_2, 1 mM CaCl_2, 5.6 mM glucose, and 0.1% BSA); a step of pre-culturing the mast cells for 30 minutes and adding 2ng/ml of antigen.
    • 目的:提供含有富酸的抗过敏组合物,以抑制各种过敏物质的分泌,并确保优异的抗过敏作用。 构成:抗过敏组合物含有黄腐酸作为活性成分。 富马酸抑制肥大细胞过敏物质的分泌,导致过敏。 肥大细胞是RBL-2H3细胞。 制备肥大细胞RBL-2H3的方法包括:在含有谷氨酰胺,抗生素和10%FBS的培养基中培养肥大细胞的步骤; 通过胰蛋白酶收集肥大细胞并用200ng / mL DNP特异性IgE培养肥大细胞的步骤; 用PIPES缓冲溶液(25mM PIPES,pH 7.2,119mM NaCl,5mM KCl,0.4mM MgCl 2,1mM CaCl 2,5.6mM葡萄糖和0.1%BSA)洗涤肥大细胞的步骤; 将肥大细胞预培养30分钟并加入2ng / ml抗原的步骤。
    • 6. 发明公开
    • 활성물질로 풀빅산을 포함하는 간질환 치료용 조성물
    • 防止皮肤酸痛的抗生素毒性
    • KR1020120108797A
    • 2012-10-05
    • KR1020110027119
    • 2011-03-25
    • 허교손지영
    • 허교손지영장경수나동희
    • A61K31/353A61K31/352A61P1/16A61P1/00
    • PURPOSE: A composition containing fulvic acid is provided to recover liver function for alcoholic fatty liver and to prevent and treat acute hepatotoxicity. CONSTITUTION: A composition for treating liver diseases contains fulvic acid as an active ingredient. The liver diseases are alcoholic fatty liver. Fulvic acid has high biological activity and easily binds with mineral and urine. The function of recovering liver function of fulvic acid in a mouse with alcoholic fatty liver is tested by biochemical analysis. [Reference numerals] (AA) Water; (BB) 20% ethanol; (CC) 0.0001% FA + 20% ethanol; (DD) 0.001% FA + 20% ethanol; (EE) 0.01% FA + 20% ethanol; (FF) 0.01% FA; (GG) 0.01% FA + 0.01% HA + 20% ethanol
    • 目的:提供含有富酸的组合物,以回收酒精性脂肪肝的肝功能,并预防和治疗急性肝毒性。 构成:用于治疗肝脏疾病的组合物含有富里酸作为活性成分。 肝脏疾病是酒精性脂肪肝。 富酸具有很高的生物活性,易与矿物和尿液结合。 通过生化分析检测酒精性脂肪肝小鼠肝脏功能恢复功能。 (附图标记)(AA)水; (BB)20%乙醇; (CC)0.0001%FA + 20%乙醇; (DD)0.001%FA + 20%乙醇; (EE)0.01%FA + 20%乙醇; (FF)0.01%FA; (GG)0.01%FA + 0.01%HA + 20%乙醇
    • 9. 发明公开
    • 풀빅산을 활성 성분으로 포함하는 항균 조성물
    • 包含油酸的细菌减少组合物
    • KR1020120108820A
    • 2012-10-05
    • KR1020110027159
    • 2011-03-25
    • 허교손지영
    • 허교손지영장경수나동희
    • A61K31/353A61K31/352A61P31/04
    • PURPOSE: An antibacterial composition containing fulvic acid is provided to ensure antibacterial effect in antibiotic resistant strain and to suppress cell wall or membrane synthesis. CONSTITUTION: An antibacterial composition contains fulvic acid as an active ingredient. The fulvic acid is isolated from natural humic substances. The natural humic substance is formed of an erosion product of organic materials in soil and is detected in soil, water, deposit, charcoal, and peat. The natural humic substances are separated to fulvic acid and humic acid by solubility difference in acid. [Reference numerals] (AA) Immediately; (BB) 15 minutes later; (CC) 30 minutes later; (DD) One hour later
    • 目的:提供含有富里酸的抗菌组合物,以确保抗生素抗性菌株的抗菌作用,抑制细胞壁或膜合成。 构成:抗菌组合物含有作为活性成分的富里酸。 黄腐酸与天然腐殖质分离。 天然腐殖质由土壤中有机物质的侵蚀产物形成,并在土壤,水,沉积物,木炭和泥炭中被检测出来。 通过酸中的溶解度差异将天然腐殖质分离成富里酸和腐殖酸。 (附图标记)(AA)立即; (BB)15分钟后 (CC)30分钟后 (DD)一小时后