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2. 发明公开

KR1020090078267A 지질대사 개선효과가 있는 데커신 및 데커시놀안젤레이트를 유효성분으로 하는 참당귀 및 세발당귀추출물과 그 추출방법 有权
标题翻译：作为影响脂质代谢改善的主要成分及其提取方法的ANGELICA GIGAS NAKAI和ANGELICA GIGAS JIRI的提取物，其具有降解作用和去甲肾上腺素
公开(公告)号：KR1020090078267A
公开(公告)日：2009-07-17
申请号：KR1020080004122
申请日：2008-01-14
申请人： 한국생명건강 (주)
发明人： 강재선 , 황성우 , 이진영 , 김강민 , 김천규 , 홍용근 , 최광진 , 이상길
IPC分类号： A61K31/37 , A61K31/352 , A61K36/232
摘要： An Angelica gigas, Nakai extract and Angelica gigas Jiri extract containing a decurshin and decursinol angelate are provided to increase weight of diabetes patient having excellent lipid improvement effect. An Angelica gigas Jiri extract concentrate reduces triglyceride concentration in blood and increase HDL(high-density lipoprotein) cholesterol concentration in blood. The Angelica gigas Jiri extract comprises a decurshin and decursinol angelate as an active ingredient. An Angelica gigas Nakai extract concentrate has lipid metabolism improving effect that increases HDL cholesterol concentration in blood in diabetes. The Angelica gigas Nakai extract concentrate comprises a decursin and decursinol angelate as an active ingredient. A method for producing the Angelica gigas Nakai or Angelica gigas Jiri comprises: a step of adding with ethanol, extracting and concentrating; a step of resolving decursin and decursinol angelate with ethanol, collecting supernatant; a step of diluting with water and resolving with ethanol; a step of centrifuging to remove impurity; a step of drying diluted ethanol layer; a step of adding hexane and water; and a step of drying hexane layer to obtain decursin and decursin angelate extract concentrate.
摘要翻译：提供含有脱屑蛋白和前胡必醇当归的当归小精子，中味提取物和当归吉拉提取物，以增加具有优异脂质改善效果的糖尿病患者的体重。当归精华提取物浓缩物能降低血液中的甘油三酯浓度，并增加血液中的HDL（高密度脂蛋白）胆固醇浓度。当归吉日萃取物含有去骨质和前胡萝卜素当归酸盐作为活性成分。当归甘草提取物浓缩物具有脂质代谢改善作用，可提高糖尿病血液中的HDL胆固醇浓度。当归黑加提取物浓缩物含有前胡素和前胡萝卜素当归酸盐作为活性成分。本发明提供当归as ai或当归茉莉的制作方法，其特征在于，添加乙醇，萃取浓缩，用乙醇溶解前胡素和前胡萝卜醇的步骤，收集上清液; 用水稀释并用乙醇分解的步骤; 离心除去杂质的步骤; 干燥乙醇层的步骤; 加入己烷和水的步骤; 和己烷层干燥步骤，得到去角质和凡士林提取物浓缩物。

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