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    • 2. 发明公开
    • 치매의 예방 또는 치료용 조성물
    • 用于治疗或保护DEMENTIA的组合物
    • KR1020100104064A
    • 2010-09-29
    • KR1020090022209
    • 2009-03-16
    • 한국과학기술연구원화중과기대
    • 양현옥권학철박진수정성권오계주완한리피혜방장붕
    • A61K36/896A61P25/28A61K31/4741A61K31/473
    • A61K31/4741A61K36/896A61K2236/333A61K2236/55
    • PURPOSE: A composition containing Lycoris aurea extract, fraction thereof, or compound isolated from the same for preventing or treating dementia is provided to apply in a single method and in a cocktail method with conventional therapeutic agent such as tacrine, donepezil, and rivastigmine. CONSTITUTION: A composition for preventing or treating dementia contains Lycoris aurea extract as an active ingredient. The Lycoris aurea extract is isolated using water or low alcohol of C1-C4. The Lycoris aurea extract is also an acetic acid ethyl fraction, butanol fraction, or mixture thereof. The composition for preventing or treating dementia contains lycoricidine of chemical formula 1, lycoricidinol of chemical formula 2, or pharmaceutically acceptable salt as an active ingredient. The dementia is Alzheimer's disease. A health food for preventing or treating dementia contains the composition.
    • 目的:提供含有Lycoris aurea提取物,其级分或从其分离的用于预防或治疗痴呆的化合物的组合物以单一方法和鸡尾酒法与常规治疗剂如他克林,多奈哌齐和利伐斯的明一起应用。 构成:用于预防或治疗痴呆的组合物含有Lycoris aurea提取物作为活性成分。 使用C1-C4的水或低级醇分离Lycoris aurea提取物。 Lycoris aurea提取物也是乙酸乙酯,丁醇馏分或其混合物。 用于预防或治疗痴呆的组合物含有化学式1的抗可乐定,化学式2的抗坏血酸醇,或其药学上可接受的盐作为活性成分。 痴呆症是阿尔茨海默病。 用于预防或治疗痴呆症的保健食品含有该组合物。