专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

KR1020080052587A 원자현미경을 이용한 생체분자간 결합 有权
标题翻译：使用原子力显微镜的生物分子相互作用
公开(公告)号：KR1020080052587A
公开(公告)日：2008-06-11
申请号：KR1020087006105
申请日：2006-08-14
申请人： 주식회사 포스코 , 포항공과대학교 산학협력단
发明人： 박준원 , 정유진 , 홍봉진 , 김일홍 , 박진규 , 류성호 , 이혜영
IPC分类号： G01N23/00 , G01N33/50 , C12Q1/68
CPC分类号： C12Q1/6816 , G01Q60/42 , B82Y35/00 , C12Q2565/601 , G01N33/50
摘要： Biomolecule interaction using an atomic force microscope is provided to analyze ligand-receptor interaction by fixing a ligand at the tip of the atomic force microscope using dendron. A cantilever for an atomic force microscope comprises a main body with a fixed end and a free end. The free end has a surface chemically deformed by dendron. The ends located on a basin of the dendron are coupled to the deformed surface. The end of linear portion of the dendron has become a functional group.
摘要翻译：提供使用原子力显微镜的生物分子相互作用，通过使用树枝状结构在原子力显微镜的尖端固定配体来分析配体 - 受体相互作用。原子力显微镜的悬臂包括具有固定端和自由端的主体。自由端具有通过树枝状化学变形的表面。位于树突的盆地上的端部与变形的表面相连。树突的直线部分的末端已经成为一个官能团。

2. 发明授权

KR101069899B1 원자현미경을 이용한 생체분자간 결합 有权
标题翻译：使用原子力显微镜的生物分子相互作用
公开(公告)号：KR101069899B1
公开(公告)日：2011-10-05
申请号：KR1020117005477
申请日：2006-08-14
申请人： 주식회사 포스코 , 포항공과대학교 산학협력단
发明人： 박준원 , 정유진 , 홍봉진 , 김일홍 , 박진규 , 류성호 , 이혜영
IPC分类号： G01Q60/24 , G01N33/50 , C12Q1/68
CPC分类号： C12Q1/6816 , G01Q60/42 , C12Q2565/601
摘要： 본발명은원자현미경(atomic force microscopy, ATM)용캔틸레버(cantilever)에관한것이다. 상기캔틸레버는고정말단과비고정말단을가진캔틸레버본체, 덴드론(dendron)의분지된부위에있는다수의말단과결합하고덴드론에의해화학적으로변형된표면부위를가진비고정말단, 및관능기화된덴드론의선형부위의말단을포함한다.

3. 发明授权

KR101742211B1 마이크로 RNA의 초민감성 정량 분석 방법 및 장치 有权
标题翻译：用于微RNA的超灵敏定量分析的方法和设备
公开(公告)号：KR101742211B1
公开(公告)日：2017-05-31
申请号：KR1020150164100
申请日：2015-11-23
申请人： 주식회사 포스코 , 포항공과대학교 산학협력단
发明人： 박준원 , 김정훈 , 김영규 , 구현서 , 이윤희
IPC分类号： C12Q1/68 , G01Q60/34 , G01Q60/42
CPC分类号： C12Q1/6837 , C12Q1/6816 , G01Q60/38 , G01Q60/42 , C12Q2522/101 , C12Q2525/207 , C12Q2565/501 , C12Q2565/601
摘要： 본발명은 DNA와 RNA의이중가닥에특이적으로결합하는하이브리드결합도메인 (hybrid binding domain, HBD)이고정된원자간력현미경의탐침을이용하여무표지의마이크로RNA를초고민감도로검출하는방법및 상기하이브리드결합도메인이고정된원자간력현미경의탐침및 무표지의마이크로 RNA를포함하는정량분석장치에관한것이다.
摘要翻译：本发明涉及一种方法，用于在所述双链杂交物结合域检测（混合结合结构域，HBD）特异性结合使用静态原子力显微镜的超DNA和RNA的非标记的灵敏度的微RNA的探针，并以及定量分析装置，其包括固定有杂交结合结构域的原子力显微镜的探针和未标记的微小RNA。

4. 发明授权

KR101439788B1 전기화학적 방법을 이용한 3차원 탄소나노튜브 네트워크 기반의 금속 또는 산화금속 나노구조체 有权
标题翻译：通过电化学方法制备碳纳米管的三维网络面向金属或金属氧化物纳米结构
公开(公告)号：KR101439788B1
公开(公告)日：2014-09-15
申请号：KR1020130099935
申请日：2013-08-22
申请人： 주식회사 포스코 , 포항공과대학교 산학협력단 , 한양대학교 산학협력단
发明人： 박준원 , 이해원 , 조석진 , 이문근 , 조용덕 , 서정은
IPC分类号： B82B3/00 , B82B1/00
CPC分类号： B82B3/0095 , B01J23/881 , B82Y40/00 , C01B32/158 , C23C14/34 , C23C16/45525 , C25D3/02
摘要： The present invention relates to a method for manufacturing a metal or metal oxide nanostructure comprising the steps of: forming a silicon pillar structure on one side of a silicon substrate; impregnating the silicon substrate with the silicon pillar structure in a catalytic solution; providing carbon source gas to the impregnated silicon substrate to form a three-dimensional network of a carbon nanotube between the silicon pillars; coating the three-dimensional network of carbon nanotube; and electrochemically depositing metal or metal oxide after coating. According to the present invention, provided is the metal or metal oxide nanostructure based on the three-dimensional carbon nanotube network with a large cross sectional area and a hierarchical structure by depositing by an electrochemical method.
摘要翻译：本发明涉及一种金属或金属氧化物纳米结构体的制造方法，包括以下步骤：在硅衬底的一侧上形成硅柱结构; 在硅催化溶液中用硅柱结构浸渍硅衬底; 向浸渍的硅衬底提供碳源气体以在硅柱之间形成碳纳米管的三维网络; 涂覆碳纳米管的三维网络; 并在涂覆后电化学沉积金属或金属氧化物。根据本发明，提供了基于具有大横截面积的三维碳纳米管网络的金属或金属氧化物纳米结构和通过电化学方法沉积的分层结构。

5. 发明授权

KR101069898B1 원자현미경을 이용한 생체분자간 결합 有权
公开(公告)号：KR101069898B1
公开(公告)日：2011-10-05
申请号：KR1020087006105
申请日：2006-08-14
申请人： 주식회사 포스코 , 포항공과대학교 산학협력단
发明人： 박준원 , 정유진 , 홍봉진 , 김일홍 , 박진규 , 류성호 , 이혜영
IPC分类号： G01N23/00 , G01N33/50 , C12Q1/68
CPC分类号： C12Q1/6816 , G01Q60/42 , C12Q2565/601
摘要： 본발명은원자현미경(atomic force microscopy, ATM)용캔틸레버(cantilever)에관한것이다. 상기캔틸레버는고정말단과비고정말단을가진캔틸레버본체, 덴드론(dendron)의분지된부위에있는다수의말단과결합하고덴드론에의해화학적으로변형된표면부위를가진비고정말단, 및관능기화된덴드론의선형부위의말단을포함한다.

6. 发明公开

KR1020110028565A 원자현미경을 이용한 생체분자간 결합 有权
标题翻译：使用原子力显微镜的生物分子相互作用
公开(公告)号：KR1020110028565A
公开(公告)日：2011-03-18
申请号：KR1020117005477
申请日：2006-08-14
申请人： 주식회사 포스코 , 포항공과대학교 산학협력단
发明人： 박준원 , 정유진 , 홍봉진 , 김일홍 , 박진규 , 류성호 , 이혜영
IPC分类号： G01Q60/24 , G01N33/50 , C12Q1/68
CPC分类号： C12Q1/6816 , G01Q60/42 , G01Q60/24 , C12Q1/6834 , C12Q2565/601
摘要： PURPOSE: Biomolecule interaction using an atomic force microscopy is provided to obtain a cantilever with fixed end and free end, the surface of which is chemically transformed due to dendrons. CONSTITUTION: A cantilever(50) includes fixed end and free end. The surface of the free end is chemically transformed due to the combination with respect to ends in the branched part of dendrons. The ends in the linear part of the dendrons are combined by probe nucleotide. A target nucleotide is fixed to a substrate(20). A modulator modulates the relative position and direction of the cantilever and the substrate. A detector measures a physical variable related to the combination of the probe and target nucleotides.
摘要翻译：目的：提供使用原子力显微镜的生物分子相互作用，以获得具有固定端和自由端的悬臂，其表面由于树枝状化学而被化学转化。构成：悬臂（50）包括固定端和自由端。由于相对于树枝状突起的分支部分中的末端的组合，自由端的表面被化学转化。通过探针核苷酸将树突状物的线性部分的末端组合。靶核苷酸被固定到基底（20）上。调制器调制悬臂和基板的相对位置和方向。检测器测量与探针和靶核苷酸的组合相关的物理变量。

7. 发明公开

KR1020130060027A 자성 입자가 탐침 끝에 도입된 ＭＦＭ용 캔틸레버 및 그 제조 방법 有权
标题翻译：具有尖端磁性颗粒的磁力显微镜和其制造方法
公开(公告)号：KR1020130060027A
公开(公告)日：2013-06-07
申请号：KR1020110126305
申请日：2011-11-29
申请人： 포항공과대학교 산학협력단
发明人： 박준원 , 김덕회 , 정낙관
IPC分类号： G01Q70/14 , G01Q70/16
CPC分类号： G01Q70/14 , G01Q60/08 , G01Q70/18 , G01R1/06727
摘要： PURPOSE: A cantilever for MFM(Magnetic Force Microscopy) and a manufacturing method thereof are provided to offer resolution entered into one or more magnetic force elements. CONSTITUTION: A cantilever(1) for MFM includes a body(5), and a probe(10) formed at the end of the body. The probe includes a magnetic force element combined with the Dendron with a bonding agent and with a surface based on the Dendron.
摘要翻译：目的：提供用于MFM（磁力显微镜）的悬臂及其制造方法，以提供进入一个或多个磁力元件的分辨率。构成：用于MFM的悬臂（1）包括主体（5）和形成在身体末端的探针（10）。探头包括与Dendron与粘合剂组合的磁力元件，并具有基于Dendron的表面。

8. 发明公开

KR1020100008022A 알카인（ａｌｋｙｎｅ）화합물의 단분자막형성방법 失效
标题翻译：包括阿尔茨基的分子单体的制备方法
公开(公告)号：KR1020100008022A
公开(公告)日：2010-01-25
申请号：KR1020080068395
申请日：2008-07-15
申请人： 포항공과대학교 산학협력단
发明人： 황찬국 , 허정무 , 김정숙 , 황광진 , 황한나 , 박준원
IPC分类号： G03F7/20 , G03F7/26
CPC分类号： G03F7/165 , C07C2/38 , G03F1/22 , G03F1/82 , G03F7/26 , G03F7/70033
摘要： PURPOSE: A method for manufacturing a molecule monolayer including an alkyne compound is provided to form a molecule monolayer of an alkyne compound in a minute and precise level from a furoxan monolayer on the surface of a substrate using extreme ultraviolet rays. CONSTITUTION: A method for manufacturing a molecule monolayer including an alkyne compound comprises: a molecular layer formation step that forms a furoxan monolayer on the surface of a substrate; and a light irradiation step that irradiates extreme ultraviolet rays to the furoxan monolayer formed in the sample preparation step. A method for forming a molecule monolayer comprises the steps of: washing a substrate for forming the furoxan monolayer; forming an APDES((3-aminoproryl)diethoxymethylsilane) molecular monolayer on the surface of washed substrate; and forming the furoxan monolayer by reacting the furoxan compound on the APDES molecular monolayer.
摘要翻译：目的：提供用于制造包含炔化合物的分子单层的方法，以使用极紫外线从基底表面上的呋喃糖单层以微细且精确的水平形成炔化合物的分子单层。构成：制造包含炔化合物的分子单层的方法包括：分子层形成步骤，在基材表面上形成呋喃糖单层; 以及向样品制备工序中形成的呋喃糖单层照射极紫外线的光照射工序。形成分子单层的方法包括以下步骤：洗涤形成呋喃糖单层的底物; 在洗涤的底物的表面上形成APDES（（3-氨基环戊基）二乙氧基甲基硅烷）分子单层; 并通过使呋喃糖化合物与APDES分子单层反应形成呋喃糖单层。

9. 发明授权

KR101737450B1 단일 세포 내 마이크로 RNA의 고해상도 시각화 방법 有权
标题翻译：单细胞microRNA的高分辨率可视化
公开(公告)号：KR101737450B1
公开(公告)日：2017-05-18
申请号：KR1020150175338
申请日：2015-12-09
申请人： 포항공과대학교 산학협력단
发明人： 박준원 , 김영규 , 박익범 , 김정훈
IPC分类号： C12Q1/68
摘要： 본발명은 (a) 표적마이크로 RNA(miRNA)가포함된생체시료상에상기표적 miRNA에상보적으로결합할수 있는염기서열을포함하는프로브 DNA를접촉시켜 DNA/RNA 혼성화체를인시츄(in-situ) 형성하는단계, 및 (b) 원자간력현미경(AFM)용캔틸레버를통해특정영역의결합힘-지도화를수행하여단일세포내 DNA/RNA 혼성화체의이중나선의존재를검출하고, 공간적분포를분석하는단계를포함하되; 상기캔틸레버는탐침및 상기탐침의표면에고정된하이브리드결합도메인(hybrid binding domain, HBD) 또는이의변이체를포함하는마이크로 RNA의고해상도시각화방법에관한것이다.
摘要翻译：（A）将包含与目标miRNA互补的碱基序列的探针DNA与含有目标微小RNA（miRNA）的生物样品接触，以制备DNA / RNA杂交产物，（b）通过原子力显微镜（AFM）悬臂执行特定区域的结合力映射来检测单个细胞中DNA / RNA杂交体的双螺旋的存在;以及分析分布; 悬臂涉及包含探针和固定在探针或其变体表面上的杂合结合结构域（HBD）的微RNA的高分辨率可视化方法。

10. 发明公开

KR1020120119909A 고체 기판 상에서 표면 결합된 올리고뉴클레오타이드를 제조하는 방법 및 이의 용도 无效
标题翻译：在固体基底上生产表面结合的寡核苷酸的方法及其用途
公开(公告)号：KR1020120119909A
公开(公告)日：2012-10-31
申请号：KR1020127015322
申请日：2009-11-16
申请人： 포항공과대학교 산학협력단
发明人： 박준원 , 홍봉진 , 김덕회
IPC分类号： C12Q1/68 , C12N15/11
CPC分类号： C12Q1/6837 , B01J2219/00387 , B01J2219/00509 , B01J2219/00529 , B01J2219/00608 , B01J2219/00612 , B01J2219/00617 , B01J2219/00621 , B01J2219/00626 , B01J2219/00653 , B01J2219/00722 , C40B80/00 , G01Q60/42 , C12Q1/6806 , B82Y30/00 , B82Y35/00 , B82Y40/00 , C12Q2565/601 , C12Q2537/113 , C12Q2533/107
摘要： PURPOSE: A manufacturing method of oligonucleotide which is surface combined on a solid surface is provided to manufacture one piece of oligonucleotide probe by covalently bonding the non-bonded oligonucleotide. CONSTITUTION: A manufacturing method of oligonucleotide which are surface combined on a solid surface comprises the following steps: contacting a first oligonucleotide with a target oligonucleotide which includes oligonucleotide sequence corresponding to the first oligonucleotide sequence under a condition which is enough for manufacturing oligonucleotide complex; contacting partially mixed oligonucleotide combination with a second oligonucleotide including the oligonucleotide sequence which corresponds with non-mixed part of the target oligonucleotide; and manufacturing oligonucleotide combination which includes the surface combined oligonucleotide. [Reference numerals] (AA) Hybridization; (BB) Leading DNA; (CC) Target DNA
摘要翻译：目的：提供在固体表面上表面组合的寡核苷酸的制造方法，以通过共价键合非键合的寡核苷酸制造一片寡核苷酸探针。构成：表面组合在固体表面上的寡核苷酸的制造方法包括以下步骤：在足以制造寡核苷酸复合物的条件下使第一寡核苷酸与包含与第一寡核苷酸序列对应的寡核苷酸序列的靶寡核苷酸接触; 使部分混合的寡核苷酸组合与包含与靶寡核苷酸的非混合部分相对应的寡核苷酸序列的第二寡核苷酸接触; 并制备包含表面结合寡核苷酸的寡核苷酸组合。（附图标记）（AA）杂交; （BB）领先DNA; （CC）靶DNA

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式