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    • 1. 发明公开
    • 포유동물의 골격결손 치유시 골이식을 위한 농축혈소판혈장겔 및 그 제조방법
    • 用于治疗骨质疏松症的骨质疏松性胶原蛋白及其制造方法
    • KR1020010055742A
    • 2001-07-04
    • KR1019990057036
    • 1999-12-13
    • 주식회사 오스코텍김종완임성빈유영목신동령김형건김종여김정근김세원임창준김성오
    • 임창준
    • A61L27/00
    • PURPOSE: A platelet-rich plasma gel for bone graft and a manufacturing method thereof are provided to improve the ability of bone forming in the case of bone restoration, and to improve the biocompatibility thereof. CONSTITUTION: The platelet-rich plasma gel for bone graft for healing skeleton deficiency of a mammal comprises platelet concentrates(PC), bone powder, calcium chloride or calcium gluconic acid, and thrombin. After centrifuging the blood collected from the mammal, the obtained upper transparent blood plasma layer and buffy layer are again centrifuged to obtain the platelet concentrates liquid(first step). The bone powder is mixed with the platelet concentrates liquid(second step), and the calcium chloride or calcium gluconic acid solution of 10 percent is mixed with the thrombin solution at the rate of 1:1(v:v)(third step). The mixture obtained at the third step is dropped in the mixture obtained at the second step to form the platelet-rich plasma gel.
    • 目的:提供一种用于骨移植的血小板富集血浆凝胶及其制造方法,以提高在骨修复的情况下的骨形成能力,并提高其生物相容性。 构成:用于治疗哺乳动物骨骼缺乏的用于骨移植物的血小板富集血浆凝胶包括血小板浓缩物(PC),骨粉,氯化钙或葡萄糖酸钙和凝血酶。 离心从哺乳动物收集的血液后,再次离心获得的上部透明血浆层和血沉棕黄层,得到血小板浓缩液(第一步)。 骨粉与血小板浓缩液(第二步)混合,10%的氯化钙或葡萄糖酸钙溶液以1:1(v:v)的速度与凝血酶溶液混合(第三步)。 将第三步得到的混合物滴加到第二步获得的混合物中以形成富含血小板的血浆凝胶。