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    • 1. 发明授权
    • 신규한 개 인플루엔자 바이러스 및 이의 백신
    • 一种新型的流行性感冒病毒和疫苗
    • KR100850545B1
    • 2008-08-05
    • KR1020070109535
    • 2007-10-30
    • 주식회사 바이오노트
    • 조영식하건우오진식강동석송대섭강보규이철승
    • C12N15/33C12N15/09C12N7/00
    • A61K39/145A61K39/12A61K2039/5252A61K2039/552A61K2039/55505C07K14/005C12N7/00C12N9/2402C12N2760/16121C12N2760/16122C12N2760/16134C12Y302/01018
    • Novel canine influenza viruses are provided to inhibit secondary infection of canine influenza viruses and develop a vaccine having improved stability against canine influenza viruses, so that the viruses are useful for prevention and treatment of influenza virus infection. A canine influenza virus of H3N2 serotype(A/Canine/Korea/01/07(H3N2)(KCTC 11205BP)) contains hemagglutinin(HA) of SEQ ID NO:1 and neuraminidase(NA) of SEQ ID NO:2. A canine influenza virus of H3N2 serotype(A/Canine/Korea/02/07(H3N2)(KCTC 11206BP)) contains hemagglutinin(HA) of SEQ ID NO:13 and neuraminidase(NA) of SEQ ID NO:14. A canine influenza virus of H3N2 serotype(A/Canine/Korea/03/07(H3N2)(KCTC 11207BP)) contains hemagglutinin(HA) of SEQ ID NO:15 and neuraminidase(NA) of SEQ ID NO:16. A vaccine composition contains the canine influenza virus or antigen thereof. Further, the vaccine is applied to dog and mixed with canine parainfluenza virus, canine distemper virus, canine adenovirus, bordetella bronchiseptica or a mixture thereof.
    • 提供新型犬流感病毒以抑制犬流感病毒的继发感染,开发具有改善针对犬流感病毒的稳定性的疫苗,使得该病毒可用于预防和治疗流感病毒感染。 H3N2血清型犬流感病毒(A / Canine / Korea / 01/07(H3N2)(KCTC 11205BP))含有SEQ ID NO:1的血凝素(HA)和SEQ ID NO:2的神经氨酸酶(NA)。 H3N2血清型犬流感病毒(A / Canine / Korea / 02/07(H3N2)(KCTC 11206BP))含有SEQ ID NO:13的血凝素(HA)和SEQ ID NO:14的神经氨酸酶(NA)。 H3N2血清型犬流感病毒(A / Canine / Korea / 03/07(H3N2)(KCTC 11207BP))含有SEQ ID NO:15的血凝素(HA)和SEQ ID NO:16的神经氨酸酶(NA)。 疫苗组合物含有犬流感病毒或其抗原。 此外,将该疫苗应用于狗并与犬副流感病毒,犬瘟热病毒,犬腺病毒,支气管炎博德特氏菌或其混合物混合。