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1. 发明公开

KR1020010076824A 도인 추출물 및 이를 함유하는 간 섬유화 억제 조성물 失效
标题翻译：用于抑制含有其的肝纤维化的双歧杆菌和组合物
公开(公告)号：KR1020010076824A
公开(公告)日：2001-08-16
申请号：KR1020000004224
申请日：2000-01-28
申请人： 손동환
发明人： 손동환 , 남극성 , 송치현
IPC分类号： A61K36/736 , A61P1/16
摘要： PURPOSE: A pharmaceutical composition containing WT-006 extracted from Persicae semen as an effective component is provided, which can inhibit fibrosis of the liver as well as protecting the liver without toxicity in the liver. CONSTITUTION: A Persicae semen extract is obtained by the process consisting of: extraction of Persicae semen with acetone, reextraction of the extract residue with methanol, cold precipitation of the obtained defatted residue, filtration and freeze-drying. The composition contains the Persicae semen extract as an effective amount to inhibit fibrosis of the liver.
摘要翻译：目的：提供含有从芍药精液提取的WT-006作为有效成分的药物组合物，其可以抑制肝脏的纤维化以及肝脏中没有毒性的保护肝脏。构成：通过以下方法获得芍药精液提取物，该方法包括：用丙酮萃取Persicae精液，用甲醇萃取残渣，冷却沉淀所得脱脂残余物，过滤冷冻干燥。该组合物含有Persicae精液提取物作为抑制肝脏纤维化的有效量。

2. 发明授权

KR100378137B1 도인 추출물 및 이를 함유하는 간 섬유화 억제 조성물 失效
标题翻译： 도인추출물및이를함유하는간섬유화억제조성물
公开(公告)号：KR100378137B1
公开(公告)日：2003-03-29
申请号：KR1020000004224
申请日：2000-01-28
申请人： 손동환
发明人： 손동환 , 남극성 , 송치현
IPC分类号： A61K36/736 , A61P1/16
摘要： PURPOSE: A pharmaceutical composition containing WT-006 extracted from Persicae semen as an effective component is provided, which can inhibit fibrosis of the liver as well as protecting the liver without toxicity in the liver. CONSTITUTION: A Persicae semen extract is obtained by the process consisting of: extraction of Persicae semen with acetone, reextraction of the extract residue with methanol, cold precipitation of the obtained defatted residue, filtration and freeze-drying. The composition contains the Persicae semen extract as an effective amount to inhibit fibrosis of the liver.
摘要翻译：目的：提供一种含有从苦瓜精液中提取的WT-006作为有效成分的药物组合物，其可以抑制肝纤维化以及在肝中保护肝脏而没有毒性。组成：由以下方法获得苦瓜精液提取物：用丙酮提取Persicae精液，用甲醇再提取残渣，冷沉淀得到的脱脂残渣，过滤并冷冻干燥。该组合物含有Persicae精液提取物作为抑制肝脏纤维化的有效量。

3. 发明授权

KR100316790B1 고산 홍경천 추출물을 함유하는 간 섬유화 억제 조성물 失效
标题翻译：具有通过含有红景天提取物A.Zol。提取物来预防肝纤维化的作用的组合物
公开(公告)号：KR100316790B1
公开(公告)日：2002-01-17
申请号：KR1019990059682
申请日：1999-12-21
申请人： 손동환
发明人： 손동환 , 남극성 , 김윤철
IPC分类号： A61K36/41 , A61P1/16
摘要： 본발명은고산홍경천(A. Bor) 물추출물의동결건조물을유효성분으로함유하여간을보호함과동시에간 섬유화를억제할수 있는약제학적조성물에관한것이다. 본발명에따른고산홍경천물추출물의동결건조물은우수한간 보호작용을나타내면서, 간독성을일으키지않으므로, 안전하게사용될수 있다.

4. 发明公开

KR1020010060396A 고산 홍경천 추출물을 함유하는 간 섬유화 억제 조성물 失效
标题翻译：含有赤霉素的肝纤维化抑制组合物A.提取物
公开(公告)号：KR1020010060396A
公开(公告)日：2001-07-07
申请号：KR1019990059682
申请日：1999-12-21
申请人： 손동환
发明人： 손동환 , 남극성 , 김윤철
IPC分类号： A61K36/41 , A61P1/16
摘要： PURPOSE: A composition for inhibiting liver fibrosis containing a freeze dried product of a Rhodiola sachalinensis A. bor extract as an effective component is provided, which inhibits liver fibrosis, together with protecting the liver and can be safely used because of generating no liver toxicity. CONSTITUTION: This liver fibrosis inhibiting composition contains a freeze dried product of a Rhodiola sachalinensis A. bor extract as an effective component, wherein the freeze dried product contains 7.5 to 8.5% by weight of salidroside. The Rhodiola sachalinensis A. bor extract is obtained by drying a root of Rhodiola sachalinensis A. bor, cutting and extracting with water at 60 to 90deg.C for 2 to 4 hr.
摘要翻译：目的：提供一种用于抑制肝纤维化的组合物，其含有红景天提取物的冻干产物作为有效成分，其抑制肝纤维化，同时保护肝脏并且由于不产生肝毒性而可以安全使用。构成：该肝纤维化抑制组合物含有作为有效成分的红景天提取物的冷冻干燥产物，其中冻干产品含有7.5至8.5重量％的沙利度胺。通过干燥Rhodiola sachalinensis A. bor根，通过在60至90℃的水中切割和提取2至4小时获得红景天提取物。

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