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    • 2. 发明公开
    • 스피노신을 포함하는 인지기능 장애 질환 예방 또는 치료용 약학조성물
    • 包含螺旋菌素用于预防和治疗认知障碍的药物组合物
    • KR1020130060835A
    • 2013-06-10
    • KR1020110127108
    • 2011-11-30
    • 대한민국 (식품의약품안전처장)경희대학교 산학협력단서울대학교산학협력단
    • 류종훈이형은강삼식김주선이소영김도훈김동섭김승희
    • A61K31/7048A61K31/70A61P25/28
    • A61K31/7048A23L2/52A23L33/10A23L33/135A23V2002/00A61K36/185A61K36/42A61K36/47A61K36/48A61K36/725
    • PURPOSE: A pharmaceutical composition containing spinosin or a spinosin-containing crude drug extract is provided to effectively improve memory and learning ability and to effectively prevent and treat cognitive disorders such as dementia and amnesia. CONSTITUTION: A composition for preventing or treating cognitive disorder contains spinosin. The composition also contains one or more extracts selected from a group consisting of Zizyphus jujuba Mill var. inermis, Zizyphus jujuba Mill var. hoonensis, Zizyphus jujuba Mill var. spinosa, Passiflora edulis flavicarpa, Cayaponia tayuya, Desmodium tortuosum, Wilbrandia ebracteata, Strophioblachia fimbricalyx, Clutia abyssinica, and Saccharopolyspora spinosa. The cognitive disorders are dementia or amnesia. A food composition for preventing or treating cognitive disorders contains spinosin. [Reference numerals] (AA) Delay time(seconds); (BB) In the middle of learning; (CC) In the middle of the present experiment; (DD) Control group 3; (EE) Control group 2; (FF) Medicine injected group 1; (GG) Medicine injected group 2; (HH) Medicine injected group 3; (II) Medicine injected group 4; (JJ) Control group 1
    • 目的:提供含有刺糖苷或含刺糖苷的生药提取物的药物组合物,有效提高记忆力和学习能力,有效预防和治疗认知障碍,如痴呆和遗忘症。 构成:用于预防或治疗认知障碍的组合物含有刺糖苷。 该组合物还含有一种或多种提取物,选自Zizyphus jujuba Mill var。 Z hus枣 枣树,枣树 菠萝,西番莲,洋葱,Cataaponia tayuya,枸杞,Wilbrandia ebracteata,Strophioblachia fimbricalyx,黑蛤和Saccharopolyspora spinosa。 认知障碍是痴呆或遗忘症。 用于预防或治疗认知障碍的食物组合物含有刺糖苷。 (附图标记)(AA)延迟时间(秒); (BB)在学习的中间; (CC)在本实验中期; (DD)对照组3; (EE)对照组2; (FF)药物注射组1; (GG)药物注射组2; (HH)药物注射组3; (二)药物注射组4; (JJ)对照组1