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    • 6. 发明公开
    • 노년 황반변성의 진단, 치료 및 예방용 조성물 및 노년 황반변성에 대한 정보를 얻기 위한 방법
    • 用于诊断和治疗年龄确定性黄斑变性的蛋白质组学生物标志物
    • KR1020120129023A
    • 2012-11-28
    • KR1020110047026
    • 2011-05-18
    • 다이아텍코리아 주식회사학교법인 건국대학교
    • 박형순강금용방주용정혜원
    • G01N33/15A61K38/43A61P27/02G01N33/68
    • PURPOSE: A proteomic biomarker for diagnosing and treating age-related macular degeneration is provided to accurately and early diagnose age-related macular degeneration. CONSTITUTION: A composition for diagnosing age-related macular degeneration contains lysozyme precursor, an autophage-related protein 7 isoform c, cathepsin D preproprotein, a keratin type II cytosekeletal 8, keratin type I cytoskeletal 9, keratin type I cytoskeletal 15, vitronectin precursor, keratin type I cytoskeletal 19, desmoplakin isoform II, complement factor I preprotein, complement factor H-related protein 1 precursor, proteasome 26S non-ATPase subunit 1, collagen alpha-2(IX) chain precursor, SPARC-like protein 1 precursor, superorixde dismutase, heat shock protein beta-1, heat shock 70kDa protein 1-analogs, 290kDa centrosomal protein, or glyceraldehyde-3-phosphate dehydrogenase. [Reference numerals] (AA) Patient 2
    • 目的:用于诊断和治疗年龄相关性黄斑变性的蛋白质组学生物标志物用于准确和早期诊断年龄相关性黄斑变性。 构成:用于诊断年龄相关性黄斑变性的组合物含有溶菌酶前体,自噬相关蛋白7同种型c,组织蛋白酶D前蛋白,角蛋白II型细胞骨架8,角蛋白I型细胞骨架9,角蛋白I型细胞骨架15,玻连蛋白前体, 角蛋白I型细胞骨架19,细丝蛋白同种型II,补体因子I前蛋白,补体因子H相关蛋白1前体,蛋白酶体26S非ATP酶亚基1,胶原α-2(IX)链前体,SPARC样蛋白1前体,超激酶 祛斑酶,热休克蛋白β-1,热休克70kDa蛋白1-类似物,290kDa中心体蛋白或甘油醛-3-磷酸脱氢酶。 (附图标记)(AA)患者2