专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2014198056A リアルタイム核酸検出法と組成物审中-公开
标题翻译：实时核酸检测方法和组合物
公开(公告)号：JP2014198056A
公开(公告)日：2014-10-23
申请号：JP2014153114
申请日：2014-07-28
申请人：エンゾライフサイエンシズ、インコーポレイテッド , Enzo Life Sciences Inc , エンゾライフサイエンシズ、インコーポレイテッド
发明人： RABBANI ELAZAR , STAVRIANOPOULOS JANNIS G , DONEGAN JAMES J , COLEMAN JACK , LIU DAKAI
IPC分类号： C12Q1/68 , G01N33/53 , C12M1/00 , C12N15/09 , G01N37/00
CPC分类号： C12Q1/6818 , C12Q1/6834 , C12Q1/6844 , C12Q1/6853 , C12Q1/686 , G01N21/64 , G01N21/6486 , C12Q2565/101 , C12Q2533/101 , C12Q2561/113
摘要：【課題】本発明は、リアルタイム核酸検出法で使用するための組成物を提供する。【解決手段】そのようなリアルタイム核酸検出法は、核酸プライマー、ヌクレオチド、核酸プローブ、または核酸結合物質に結合した、エネルギー移動要素を用いて行われる。リアルタイム核酸検出は、試料中の目的の1本鎖または2本鎖核酸の定性的または定量的検出または測定を可能にする。ホモポリマー配列の一部(例えば、ポリA配列またはテイル)を、アナライトまたはアナライトのライブラリーから除去する方法を含む他の方法が提供される。そのような除去法を実施するのに有用な組成物も、記載され提供される。【選択図】なし
摘要翻译：要解决的问题：提供用于实时核酸检测过程的组合物。解决方案：这种实时核酸检测过程用连接到核酸引物，核苷酸，核酸探针或核酸的能量转移元件进行粘合剂。实时核酸检测允许定性或定量检测或测定样品中感兴趣的单链或双链核酸。提供了其它方法，包括从分析物或分析物库中除去一部分均聚物序列，例如聚A序列或尾部的方法。还描述和提供了用于进行这种去除方法的组合物。

2. 发明专利

JP2003334097A Real time nucleic acid detection method and composition 有权
标题翻译：实时核酸检测方法及组合物
公开(公告)号：JP2003334097A
公开(公告)日：2003-11-25
申请号：JP2003114989
申请日：2003-03-11
申请人： Enzo Life Sciences Inc , エンゾライフサイエンシズ、インコーポレイテッド
发明人： RABBANI ELAZAR , STAVRIANOPOULOS JANNIS G , DONEGAN JAMES J , COLEMAN JACK , LIU DAKAI
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N37/00
CPC分类号： C12Q1/6818 , C12Q1/6834 , C12Q1/6844 , C12Q1/6853 , C12Q1/686 , G01N21/64 , G01N21/6486 , C12Q2565/101 , C12Q2533/101 , C12Q2561/113
摘要： PROBLEM TO BE SOLVED: To obtain a composition useful in a real-time nucleic acid detection method. SOLUTION: The real-time nucleic acid detection method is carried out by using a nucleic acid primer, a nucleotide, a nucleic acid probe or an energy moving element bonded to a nucleic acid linked substance. The real-time nucleic acid detection enables qualitative or quantitative detection of the objective single-stranded double-stranded nucleic acid in a sample. A method including a method for removing a part of a homopolymer sequence (e.g. poly(A) sequence or poly(A) tail) from analyte or an analyte library. The composition useful for the removal method is also obtained. COPYRIGHT: (C)2004,JPO
摘要翻译：待解决的问题：获得用于实时核酸检测方法的组合物。解决方案：实时核酸检测方法通过使用与核酸连接物质结合的核酸引物，核苷酸，核酸探针或能量移动元件进行。实时核酸检测能够定性或定量检测样品中目的单链双链核酸。一种包括从分析物或分析物库中除去一部分均聚物序列（例如聚（A）序列或聚（A）尾）的方法。还获得了可用于除去方法的组合物。版权所有（C）2004，JPO

3. 发明专利

JP2010200760A Method and composition for real time nucleic acid detection 有权
标题翻译：用于实时核酸检测的方法和组合物
公开(公告)号：JP2010200760A
公开(公告)日：2010-09-16
申请号：JP2010117243
申请日：2010-05-21
申请人： Enzo Life Sciences Inc , エンゾライフサイエンシズ、インコーポレイテッド
发明人： RABBANI ELAZAR , STAVRIANOPOULOS JANNIS G , DONEGAN JAMES J , COLEMAN JACK , LIU DAKAI
IPC分类号： C12Q1/68 , G01N33/53 , C12M1/00 , C12N15/09 , G01N37/00
CPC分类号： C12Q1/6818 , C12Q1/6834 , C12Q1/6844 , C12Q1/6853 , C12Q1/686 , G01N21/64 , G01N21/6486 , C12Q2565/101 , C12Q2533/101 , C12Q2561/113
摘要： PROBLEM TO BE SOLVED: To provide a composition for use in real time nucleic acid detection. SOLUTION: The real time nucleic acid detection methods are carried out with energy transfer elements attached to nucleic acid primers, nucleotides, nucleic acid probes or nucleic acid binding agents. Real time nucleic acid detection allows for the qualitative or quantitative detection or determination of single-stranded or double-stranded nucleic acids of interest in a sample. Other methods are provided to include processes for removing a part of a homopolymeric sequence, (e.g., poly A sequence or tail), from an analyte or library of analytes. Compositions useful in carrying out such removal methods are also described and provided. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供用于实时核酸检测的组合物。解决方案：实时核酸检测方法用与核酸引物，核苷酸，核酸探针或核酸结合剂连接的能量转移元件进行。实时核酸检测允许定性或定量检测或测定样品中感兴趣的单链或双链核酸。提供了其它方法以包括从分析物或分析物库中除去一部分均聚物序列（例如聚A序列或尾部）的方法。还描述和提供了用于实施这种去除方法的组合物。版权所有（C）2010，JPO＆INPIT

4. 发明专利

JP2010017196A Real-time nucleic acid detection process and composition 有权
标题翻译：实时核酸检测过程及组成
公开(公告)号：JP2010017196A
公开(公告)日：2010-01-28
申请号：JP2009246566
申请日：2009-10-27
申请人： Enzo Life Sciences Inc , エンゾライフサイエンシズ、インコーポレイテッド
发明人： RABBANI ELAZAR , STAVRIANOPOULOS JANNIS G , DONEGAN JAMES J , COLEMAN JACK , LIU DAKAI
IPC分类号： C12N15/09 , G01N33/53 , C07K14/01 , C07K14/245 , C07K14/37 , C07K14/415 , C07K14/435 , C07K16/00 , C12M1/00 , C12Q1/68 , G01N33/542 , G01N37/00
CPC分类号： C12Q1/6818 , C12Q1/6834 , C12Q1/6844 , C12Q1/6853 , C12Q1/686 , G01N21/64 , G01N21/6486 , C12Q2565/101 , C12Q2533/101 , C12Q2561/113
摘要： PROBLEM TO BE SOLVED: To provide compositions for use in real time nucleic acid detection processes. SOLUTION: Such real time nucleic acid detection processes are carried out with energy transfer elements attached to nucleic acid primers, nucleotides, nucleic acid probes or nucleic acid binding agents. Real time nucleic acid detection allows for the qualitative or quantitative detection or determination of single-stranded or double-stranded nucleic acids of interest in a sample. Other processes are provided including processes for removing a portion of a homopolymeric sequence, (e.g., poly A sequence or tail), from an analyte or library of analytes. Compositions useful in carrying out such removal processes are also described and provided. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供用于实时核酸检测过程的组合物。解决方案：这种实时核酸检测方法是用与核酸引物，核苷酸，核酸探针或核酸结合剂连接的能量转移元件进行的。实时核酸检测允许定性或定量检测或测定样品中感兴趣的单链或双链核酸。提供了其它方法，包括从分析物或分析物库中除去一部分均聚物序列（例如，聚A序列或尾部）的方法。还描述和提供了用于进行这种去除方法的组合物。版权所有（C）2010，JPO＆INPIT

5. 发明专利

JP2003088390A NEW COMPOSITION AND PROCESS FOR DETECTION, QUANTIFICATION AND AMPLIFICATION OF ANALYTE 审中-公开
公开(公告)号：JP2003088390A
公开(公告)日：2003-03-25
申请号：JP2002192771
申请日：2002-07-01
申请人： ENZO LIFE SCIENCES INC
发明人： RABBANI ELAZAR , STAVRIANOPOULOS JANNIS G , DONEGAN JAMES J , COLEMAN JACK
IPC分类号： G01N33/53 , C07B61/00 , C07H21/00 , C07K17/02 , C12M1/00 , C12N15/09 , C12Q1/00 , C40B40/02 , C40B50/06 , G01N33/58 , G01N37/00 , C12Q1/68
摘要： PROBLEM TO BE SOLVED: To provide a new composition and process for detection, quantification and amplification of an analyte. SOLUTION: The composition and process are obtained by usefully incorporating a nucleic acid array and a library of the analyte. Universal detection elements, signaling entities, etc., are employed to detect the analyte and, if necessary or desirable, to further quantify the analyte. The amplification of the target analyte is also provided by the composition and process.

6. 发明专利

JP2009112317A New composition and process for analyte detection, quantification and amplification 审中-公开
标题翻译：用于分析物检测，定量和放大的新组合物和方法
公开(公告)号：JP2009112317A
公开(公告)日：2009-05-28
申请号：JP2009050273
申请日：2009-03-04
申请人： Enzo Life Sciences Inc , エンゾーライフサイエンセズインコーポレイテッド
发明人： RABBANI ELAZAR , STAVRIANOPOULOS JANNIS G , DONEGAN JAMES J , COLEMAN JACK
IPC分类号： C12Q1/68 , G01N33/53 , C07B61/00 , C07H21/00 , C07K17/02 , C12M1/00 , C12N15/09 , C12Q1/00 , C40B40/02 , C40B50/06 , G01N33/58 , G01N37/00
CPC分类号： C40B40/06 , B01J19/0046 , B01J2219/00599 , B01J2219/0061 , B01J2219/00612 , B01J2219/00648 , B01J2219/00722 , B01J2219/00725 , C07B2200/11 , C07H21/00 , C12N15/1006 , C12N15/1058 , C12Q1/68 , C12Q1/6809 , C12Q1/6825 , C12Q1/6837 , C40B40/00 , C40B40/10 , G01N33/68 , C12Q2565/501 , C12Q2563/179 , C12Q2545/114 , C12Q2525/155 , C12Q2565/514 , C12Q2565/537
摘要： PROBLEM TO BE SOLVED: To provide new compositions and processes for analyte detection, quantification and amplification. SOLUTION: Nucleic acid arrays and libraries of analytes are usefully incorporated into the compositions and the processes. Universal detection elements, signaling entities and the like are employed to detect analytes and if necessary or desirable, to quantify further. Amplifications of target analytes are also provided by the compositions and processes. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：为分析物检测，定量和扩增提供新的组合物和方法。解决方案：分析物的核酸阵列和文库有效地并入组合物和方法中。通用检测元件，信号实体等用于检测分析物，如果需要或需要，进一步量化。靶分析物的扩增也由组合物和方法提供。版权所有（C）2009，JPO＆INPIT

7. 发明专利

JP2008017853A New composition and process for analyte detection, quantification and amplification 审中-公开
标题翻译：用于分析物检测，定量和放大的新组合物和方法
公开(公告)号：JP2008017853A
公开(公告)日：2008-01-31
申请号：JP2007241620
申请日：2007-09-18
申请人： Enzo Life Sciences Inc , エンゾーライフサイエンセズインコーポレイテッド
发明人： RABBANI ELAZAR , STAVRIANOPOULOS JANNIS G , DONEGAN JAMES J , COLEMAN JACK
IPC分类号： C12Q1/68 , G01N33/53 , C07B61/00 , C07H21/00 , C07K17/02 , C12M1/00 , C12N15/09 , C12Q1/00 , C40B40/02 , C40B50/06 , G01N33/543 , G01N33/545 , G01N33/547 , G01N33/548 , G01N33/58 , G01N37/00
CPC分类号： C40B40/06 , B01J19/0046 , B01J2219/00599 , B01J2219/0061 , B01J2219/00612 , B01J2219/00648 , B01J2219/00722 , B01J2219/00725 , C07B2200/11 , C07H21/00 , C12N15/1006 , C12N15/1058 , C12Q1/68 , C12Q1/6809 , C12Q1/6825 , C12Q1/6837 , C40B40/00 , C40B40/10 , G01N33/68 , C12Q2565/501 , C12Q2563/179 , C12Q2545/114 , C12Q2525/155 , C12Q2565/514 , C12Q2565/537
摘要： PROBLEM TO BE SOLVED: To provide new compositions and processes for analyte detection, quantification and amplification. SOLUTION: Nucleic acid arrays and libraries of analytes are usefully incorporated into the compositions and the processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplifications of target analytes are also provided by the compositions and processes. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为分析物检测，定量和扩增提供新的组合物和方法。解决方案：分析物的核酸阵列和文库有效地并入组合物和方法中。使用通用检测元件，信号实体等来检测并且如果需要或期望量化分析物。靶分析物的扩增也由组合物和方法提供。版权所有（C）2008，JPO＆INPIT

8. 发明申请

WO2014018278A2 MULTISIGNAL REAGENTS FOR LABELING ANALYTES 审中-公开
标题翻译：用于标记分析的多重信号试剂
公开(公告)号：WO2014018278A2
公开(公告)日：2014-01-30
申请号：PCT/US2013050202
申请日：2013-07-12
申请人： ENZO LIFE SCIENCES INC , COLEMAN JACK , SZCZEPANIK MACIEJ , JIN RICHARD
发明人： COLEMAN JACK , SZCZEPANIK MACIEJ , JIN RICHARD
IPC分类号： C12N11/02 , C07H21/04 , C07K14/36
CPC分类号： G01N33/54306 , C12Q1/68 , G01N33/58
摘要： Provided is a composition comprising an analyte bound covalently or through a first binding pair to a polymer. In this composition, the analyte is less than about 2000 MW; the polymer further comprises more than one signal or first member of a second binding pair; and the analyte is not a member of the first binding pair or the second binding pair. Also provided is an assay for an analyte. The assay comprises: combining a sample suspected of containing the analyte with the above-described composition and a binding agent that binds to the analyte; and detecting the signal or the first member of the second binding pair that is bound to the binding agent. In this assay, the amount of the signal or the first member of the second binding pair bound to the binding agent is inversely proportional to the analyte in the sample. Additionally provided is a multisignal labeling reagent comprising a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule.
摘要翻译：提供了包含共价结合或通过第一结合对与聚合物结合的分析物的组合物。在该组合物中，分析物小于约2000MW; 该聚合物还包含多于一个信号或第二结合对的第一成员; 并且分析物不是第一结合对或第二结合对的成员。还提供了分析物的分析。该测定包括：将怀疑含有分析物的样品与上述组合物和结合分析物的结合剂组合; 以及检测与结合剂结合的信号或第二结合对的第一成员。在该测定中，与结合剂结合的信号或第二结合对的第一成员的量与样品中的分析物成反比。另外提供一种多信号标记试剂，其包含与（a）第一结合对的反应基团或第一成员共价结合的第一聚合物，和（b）多于一种地高辛配基分子。

9. 发明申请

WO2014018278A9 MULTISIGNAL REAGENTS FOR LABELING ANALYTES 审中-公开
标题翻译：用于标签分析的多种试剂
公开(公告)号：WO2014018278A9
公开(公告)日：2014-08-28
申请号：PCT/US2013050202
申请日：2013-07-12
申请人： ENZO LIFE SCIENCES INC , COLEMAN JACK , SZCZEPANIK MACIEJ , JIN RICHARD
发明人： COLEMAN JACK , SZCZEPANIK MACIEJ , JIN RICHARD
IPC分类号： G01N33/58
CPC分类号： G01N33/54306 , C12Q1/68 , G01N33/58
摘要： Provided is a composition comprising an analyte bound covalently or through a first binding pair to a polymer. In this composition, the analyte is less than about 2000 MW; the polymer further comprises more than one signal or first member of a second binding pair; and the analyte is not a member of the first binding pair or the second binding pair. Also provided is an assay for an analyte. The assay comprises: combining a sample suspected of containing the analyte with the above-described composition and a binding agent that binds to the analyte; and detecting the signal or the first member of the second binding pair that is bound to the binding agent. In this assay, the amount of the signal or the first member of the second binding pair bound to the binding agent is inversely proportional to the analyte in the sample. Additionally provided is a multisignal labeling reagent comprising a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule.
摘要翻译：提供了包含共价键合或通过第一结合对与聚合物结合的分析物的组合物。在该组合物中，分析物小于约2000MW; 聚合物还包含多于一个信号或第二结合对的第一个成员; 并且分析物不是第一结合对或第二结合对的成员。还提供了分析物的测定。该测定包括：将怀疑含有分析物的样品与上述组合物结合，和结合分析物的结合剂; 以及检测绑定到绑定剂的第二绑定对的信号或第一成员。在该测定中，与结合剂结合的信号或第二结合对的第一个成员的量与样品中的分析物成反比。另外提供了包含共价结合到（a）第一结合对的反应性基团或第一个成员的第一聚合物的多信号标记试剂，和（b）多于一个的地高辛分子。

10. 发明申请

WO2011065980A2 DYES FOR ANALYSIS OF PROTEIN AGGREGATION 审中-公开
标题翻译：用于分析蛋白质聚集的染料
公开(公告)号：WO2011065980A2
公开(公告)日：2011-06-03
申请号：PCT/US2010003061
申请日：2010-11-30
申请人： ENZO LIFE SCIENCES INC , PATTON WAYNE FORREST , YARMOLUK SERGIY M , PANDE PRAVEEN , KOVALSKA VLADYSLAVA , DAI LIJUN , VOLKOVA KATERYNA , COLEMAN JACK , LOSYTSKYY MYKHAYLO , LUDLAM ANTHONY , BALANDA ANATOLIY , SHEN DEE
发明人： PATTON WAYNE FORREST , YARMOLUK SERGIY M , PANDE PRAVEEN , KOVALSKA VLADYSLAVA , DAI LIJUN , VOLKOVA KATERYNA , COLEMAN JACK , LOSYTSKYY MYKHAYLO , LUDLAM ANTHONY , BALANDA ANATOLIY , SHEN DEE
IPC分类号： C09B23/14
CPC分类号： C09B23/145 , C07D401/12 , C09B23/0008 , C09B23/0025 , C09B23/0058 , C09B23/0066 , C09B23/04 , C09B23/06 , C09B23/102 , C09B23/141 , G01N33/582 , G01N33/6845 , G01N2458/30 , G01N2800/2821 , G01N2800/2835
摘要： Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, and analysis of molecular chaperone activity.
摘要翻译：提供可用于许多应用的染料和组合物，例如检测和监测蛋白质聚集，蛋白质聚集的动力学研究，神经原纤维斑块分析，蛋白质制剂稳定性的评估和分子伴侣活性的分析。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式