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    • 5. 发明公开
    • (-)카테친을 함유하는 아디포넥틴 발현 증강제
    • ADIPONECTIN表达增强剂( - )CATECHIN
    • KR1020070106822A
    • 2007-11-06
    • KR1020060039138
    • 2006-05-01
    • (주)아모레퍼시픽
    • 조시영박필준신현정김영경신동욱신의석이형호이병곤백주현이태룡
    • A61K31/353A61P3/10
    • A61K31/353
    • A composition containing (-)catechin is provided to increase expression of adiponectin by inhibiting expression of a transition factor KLF7(Kruppel-like factor 7) and promotes sugar absorption in adipocytes of mammals, so that the composition is useful for preventing and treating diabetes mellitus, arteriosclerosis and obesity. A composition for preventing and treating diabetes mellitus, arteriosclerosis and obesity contains 0.01-30 wt.%, preferably 1-15 wt.% of (-)catechin represented by the formula(1), wherein the (-)catechin is isolated from green tea. The daily dosage of (-)catechin is 0.1-50 mg/kg, preferably 1-20 mg/kg and the expression of adiponectin in a mammal adipocyte is increased by treating an adipocyte with (-)catechin for 24 hours.
    • 提供含有( - )儿茶素的组合物,通过抑制转录因子KLF7(Kruppel样因子7)的表达来增加脂联素的表达,并促进哺乳动物脂肪细胞中的糖吸收,使得该组合物可用于预防和治疗糖尿病 ,动脉硬化和肥胖。 用于预防和治疗糖尿病,动脉硬化和肥胖症的组合物含有0.01-30重量%,优选1-15重量%的由式(1)表示的( - )儿茶素,其中( - )儿茶素与绿色分离 茶。 ( - )儿茶素的日剂量为0.1-50mg / kg,优选为1-20mg / kg,通过用( - )儿茶素处理脂肪细胞24小时,哺乳动物脂肪细胞中脂联素的表达增加。
    • 6. 发明公开
    • 식물 추출물을 함유하는 지질 분해 촉진용 조성물
    • 用于促进含脂肪植物提取物降解的组合物
    • KR1020070072359A
    • 2007-07-04
    • KR1020060119575
    • 2006-11-30
    • (주)아모레퍼시픽
    • 신동욱신의석이형호이태룡조시영장이섭
    • A61K36/904A61K36/70A61P3/04
    • A composition comprising a plant extract is provided to activate the TCA cycle by inducing the IDH3alpha(isocitrate dehydrogenase) gene promoter, thereby promoting the decomposition of lipid and preventing and treating obesity and hyperlipidemia. The composition comprises at least one plant extract selected from the group consisting of an extract of Belamcandae Rhizoma, an extract of Galium spurium, an extract of Persicaria hydropiper, an extract of Chrysanthemum zawadskii var. lucidum, an extract of Pinus koraiensis, and an extract of Cryptotaenia japonica. The extract is prepared by using a solvent selected from the group consisting of ethanol, methanol, butanol, ethylacetate, chloroform and hexane.
    • 提供包含植物提取物的组合物以通过诱导IDH3α(异柠檬酸脱氢酶)基因启动子来激活TCA循环,从而促进脂质分解并预防和治疗肥胖症和高脂血症。 所述组合物包含至少一种植物提取物,所述植物提取物选自枸杞提取物,an an提取物,水an提取物,菊花提取物。 灵芝,红松提取物,枸杞提取物。 通过使用选自乙醇,甲醇,丁醇,乙酸乙酯,氯仿和己烷的溶剂制备提取物。