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    • 6. 发明公开
    • 창상치유능력이 향상된 줄기세포 배양액 및 그의 제조방법
    • 具有增强愈合愈合活性的培养基和其制备方法
    • KR1020120075269A
    • 2012-07-06
    • KR1020100137333
    • 2010-12-28
    • (주)노바셀테크놀로지
    • 이태훈김재윤
    • C12N5/0775A61K35/28
    • C12N5/0663A61K35/28C12N5/0668C12N2500/36
    • PURPOSE: A stem cell culture medium for an improved wound healing function is provided to promote epithelial tissue regeneration, skin regeneration, and angiogenesis without side effects. CONSTITUTION: A stem cell culture medium with improved wound healing function is prepared by treating LPA(lysophosphatidic acid) to a medium for culturing stem cells before or during stem cell culture. The stem cell is derived from the human body and includes embryonic stem cells, adult stem cells, or stem cell culture liquid. A composition for treating or preventing wound contains the stem cell culture liquid as an active ingredient. A method for preparing the stem cell culture liquid comprises: a step of treating a medium for culturing stem cells before or during culturing with LPA; a step of culturing stem cells in an LPA-treated medium; and a step of collecting the culture medium.
    • 目的:提供一种用于改善伤口愈合功能的干细胞培养基,以促进上皮组织再生,皮肤再生和血管生成而无副作用。 构成:通过在干细胞培养之前或期间将LPA(溶血磷脂酸)处理至用于培养干细胞的培养基来制备具有改善伤口愈合功能的干细胞培养基。 干细胞衍生自人体,包括胚胎干细胞,成体干细胞或干细胞培养液。 用于治疗或预防伤口的组合物含有作为活性成分的干细胞培养液。 制备干细胞培养液的方法包括:在用LPA培养之前或培养期间处理用于培养干细胞的培养基的步骤; 在LPA处理的培养基中培养干细胞的步骤; 和收集培养基的步骤。
    • 10. 发明公开
    • 콜라겐 합성능이 있는 신규 펩타이드 유도체 및 그의 용도
    • 合成胶原蛋白的新肽衍生物及其用途
    • KR1020130055505A
    • 2013-05-28
    • KR1020120066864
    • 2012-06-21
    • (주)노바셀테크놀로지
    • 이태훈김재윤김범준
    • C07K7/06C07K7/08C07K14/00A61K8/64
    • PURPOSE: A novel peptide derivative with collagen synthesis ability is provided to promote collagen synthesis and wound healing and to improve anti-aging and anti-wrinkling effects. CONSTITUTION: A peptide derivative contains a palmitoyl group at N-terminal of a peptide with 5-100 amino acids including YIGSR of sequence number 1. The peptide has 5-20 amino acids. The peptide has an amino acid sequence of sequence number 1. A composition for anti-aging, a cosmetic composition for anti-wrinkling, and a pharmaceutical composition for wound healing contain the peptide derivative or YIGSR peptide as an active ingredient. A skin filler contains the peptide derivative or YIGSR peptide as an active ingredient.
    • 目的:提供具有胶原合成能力的新型肽衍生物,促进胶原合成和伤口愈合,提高抗衰老和抗皱效果。 构成:肽衍生物在具有5-100个氨基酸的肽的N末端含有棕榈酰基,包括序列号1的YIGSR。肽具有5-20个氨基酸。 肽具有序列号1的氨基酸序列。抗衰老组合物,抗皱化妆品组合物和用于伤口愈合的药物组合物含有肽衍生物或YIGSR肽作为活性成分。 皮肤填充剂含有肽衍生物或YIGSR肽作为活性成分。