专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09283300B2 Use of midkine protein and the protein-containing medical device 有权
标题翻译：使用中期蛋白和含蛋白质的医疗器械
公开(公告)号：US09283300B2
公开(公告)日：2016-03-15
申请号：US13322443
申请日：2010-05-25
申请人： Wei Han , Zhonghui Zhang
发明人： Wei Han , Zhonghui Zhang
IPC分类号： A61K38/17 , A61P19/02 , A61L27/54 , A61L27/24 , A61L27/22 , A61K38/18 , A61F2/30
CPC分类号： A61L27/227 , A61F2/30756 , A61F2002/30677 , A61K38/18 , A61L27/54 , A61L2300/252 , A61L2300/414 , A61L2430/06
摘要： The applications and medical devices of Midkine in the field of biotechnology are described in this invention. This invention describes the applications of the protein as follow in (a) or (b) in preparing drugs for promoting cartilage growth or treating cartilage diseases, the protein as a growth factor for promoting chondrocyte proliferation, or medical devices containing this protein: (a) the protein whose amino acid sequence is shown as SEQ ID NO.1; (b) the proteins whose amino acid sequence have at least 60% homology comparing with amino acid sequence described in (a). The present invention is different from the present knowledge of MK and its related proteins. The experimental results demonstrated that MK promotes proliferation of three types of chondrocytes and is used for preparing drugs for treating cartilage disease. It may provide new therapy for treating cartilage diseases clinically, and new technology for expansion of chondrocytes in vitro for cartilage tissue engineering.
摘要翻译：本发明描述了Midkine在生物技术领域的应用和医疗设备。本发明描述了如下（a）或（b）中的蛋白质在制备用于促进软骨生长或治疗软骨疾病的药物中的应用，所述蛋白质作为促进软骨细胞增殖的生长因子，或含有该蛋白质的医学装置：（a ）其氨基酸序列显示为SEQ ID NO.1的蛋白质; （b）与（a）中所述的氨基酸序列相比，其氨基酸序列具有至少60％同源性的蛋白质。本发明与MK及其相关蛋白质的现有知识不同。实验结果表明，MK促进三种软骨细胞增殖，用于制备治疗软骨疾病的药物。可能提供临床治疗软骨疾病的新疗法，软骨组织工程体外软骨细胞扩增的新技术。

2. 发明授权

US08746093B2 Oil pumping unit 有权
标题翻译：抽油机
公开(公告)号：US08746093B2
公开(公告)日：2014-06-10
申请号：US13171495
申请日：2011-06-29
申请人： Minxuan Wang , Jianli Xu , Zhengquan Cheng , Bin Wei , Zhonghui Zhang , Bingsheng Liu , Guangqi Gao , Yan Luo , Zejun Zhu
发明人： Minxuan Wang , Jianli Xu , Zhengquan Cheng , Bin Wei , Zhonghui Zhang , Bingsheng Liu , Guangqi Gao , Yan Luo , Zejun Zhu
IPC分类号： F16H21/32 , F16H21/44 , F04B17/00
CPC分类号： E21B43/126
摘要： A crank-type non-beam pumping unit, including a belt, a foundation, a crown sheave, a frame, a support rod, a belt pulley, a pin shaft, a crank, a transmission shaft, and a bracket. The bottom of the frame is disposed on the foundation, and the top of the frame is supported by the support rod. The top of the support rod is hinge connected to the frame, and the bottom of the support rod is hinge connected to the foundation. The bracket is disposed on the foundation, the transmission shaft is disposed on the bracket, and the crank is disposed on the transmission shaft. The crank rotates synchronously with the transmission shaft, and the belt pulley is disposed on one end of the crank via the pin shaft. One end of the belt bypasses the crown sheave, and is connected to a smooth sucker rod.
摘要翻译：曲柄式无梁泵送单元，包括皮带，基座，表头滑轮，框架，支撑杆，皮带轮，销轴，曲柄，传动轴和支架。框架的底部设置在基座上，框架的顶部由支撑杆支撑。支撑杆的顶部铰链连接到框架，支撑杆的底部铰链连接到基座。支架设置在基座上，传动轴设置在支架上，曲柄设置在传动轴上。曲柄与传动轴同步旋转，皮带轮通过销轴设置在曲柄的一端。皮带的一端绕过表冠滑轮，并连接到平滑的吸盘上。

3. 发明申请

US20110318199A1 OIL PUMPING UNIT 有权
标题翻译：油泵单元
公开(公告)号：US20110318199A1
公开(公告)日：2011-12-29
申请号：US13171495
申请日：2011-06-29
申请人： Minxuan WANG , Jianli XU , Zhengquan CHENG , Bin WEI , Zhonghui ZHANG , Bingsheng LIU , Guangqi GAO , Yan LUO , Zejun ZHU
发明人： Minxuan WANG , Jianli XU , Zhengquan CHENG , Bin WEI , Zhonghui ZHANG , Bingsheng LIU , Guangqi GAO , Yan LUO , Zejun ZHU
IPC分类号： F04B53/00
CPC分类号： E21B43/126
摘要： A crank-type non-beam pumping unit, including a belt, a foundation, a crown sheave, a frame, a support rod, a belt pulley, a pin shaft, a crank, a transmission shaft, and a bracket. The bottom of the frame is disposed on the foundation, and the top of the frame is supported by the support rod. The top of the support rod is hinge connected to the frame, and the bottom of the support rod is hinge connected to the foundation. The bracket is disposed on the foundation, the transmission shaft is disposed on the bracket, and the crank is disposed on the transmission shaft. The crank rotates synchronously with the transmission shaft, and the belt pulley is disposed on one end of the crank via the pin shaft. One end of the belt bypasses the crown sheave, and is connected to a smooth sucker rod.
摘要翻译：曲柄式无梁泵送单元，包括皮带，基座，表头滑轮，框架，支撑杆，皮带轮，销轴，曲柄，传动轴和支架。框架的底部设置在基座上，框架的顶部由支撑杆支撑。支撑杆的顶部铰链连接到框架，支撑杆的底部铰链连接到基座。支架设置在基座上，传动轴设置在支架上，曲柄设置在传动轴上。曲柄与传动轴同步旋转，皮带轮通过销轴设置在曲柄的一端。皮带的一端绕过表冠滑轮，并连接到平滑的吸盘上。

4. 发明申请

US20120108516A1 THE USE OF MIDKINE PROTEIN AND THE PROTEIN-CONTAINING MEDICAL DEVICE 有权
标题翻译：中蛋白和含蛋白质医疗器械的使用
公开(公告)号：US20120108516A1
公开(公告)日：2012-05-03
申请号：US13322443
申请日：2010-05-25
申请人： Wei Han , Zhonghui Zhang
发明人： Wei Han , Zhonghui Zhang
IPC分类号： A61K38/17 , A61P19/00 , C07K14/435
CPC分类号： A61L27/227 , A61F2/30756 , A61F2002/30677 , A61K38/18 , A61L27/54 , A61L2300/252 , A61L2300/414 , A61L2430/06
摘要： The applications and medical devices of Midkine in the field of biotechnology are described in this invention. This invention describes the applications of the protein as follow in (a) or (b) in preparing drugs for promoting cartilage growth or treating cartilage diseases, the protein as a growth factor for promoting chondrocyte proliferation, or medical devices containing this protein: (a) the protein whose amino acid sequence is shown as SEQ ID NO.1; (b) the proteins whose amino acid sequence have at least 60% homology comparing with amino acid sequence described in (a) and have activity for promoting proliferation of chondrocyte. The protein described in this invention promotes proliferation of three types of chondrocytes and is used for preparing drugs for treating cartilage disease. It may provide new therapy for treating cartilage diseases clinically, and new technology for expansion of chondrocytes in vitro for cartilage tissue engineering.
摘要翻译：本发明描述了Midkine在生物技术领域的应用和医疗设备。本发明描述了如下（a）或（b）中的蛋白质在制备用于促进软骨生长或治疗软骨疾病的药物中的应用，所述蛋白质作为促进软骨细胞增殖的生长因子，或含有该蛋白质的医学装置：（a ）其氨基酸序列显示为SEQ ID NO.1的蛋白质; （b）与（a）所述的氨基酸序列相比，其氨基酸序列具有至少60％同源性且具有促进软骨细胞增殖的活性的蛋白质。本发明描述的蛋白质促进三种软骨细胞的增殖，并用于制备治疗软骨疾病的药物。可能提供临床治疗软骨疾病的新疗法，软骨组织工程体外软骨细胞扩增的新技术。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式