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1. 发明申请

US20120095305A1 Spectrophotometric Monitoring Of Multiple Layer Tissue Structures 审中-公开
标题翻译：多层组织结构的分光光度监测
公开(公告)号：US20120095305A1
公开(公告)日：2012-04-19
申请号：US12815696
申请日：2010-06-15
申请人： Ming Wang , Shih-Ping Wang , Zengpin Yu , Wei Zhang
发明人： Ming Wang , Shih-Ping Wang , Zengpin Yu , Wei Zhang
IPC分类号： A61B5/1455 , A61B6/00
CPC分类号： A61B5/0075 , A61B5/103 , A61B5/14551
摘要： Methods, systems, and related computer program products for the non-invasive spectrophotometric monitoring of a biological volume having multiple tissue layers are described. Aggregate absorption and scattering properties are measured for each of a plurality of predetermined source-detector separation distances along a surface of the biological volume, the measurement being based on a model of the biological volume as a single-layer, semi-infinite, homogeneous volume. A predetermined multi-layer tissue model is retrieved that characterizes a mathematical relationship among (a) absorption and scattering properties of each layer of a multi-layer tissue structure, and (b) aggregate absorption and scattering properties of the multi-layer tissue structure as would be measured at selected source-detector separation distances along a surface thereof. The measured aggregate absorption and scattering properties are processed in conjunction with the predetermined multi-layer tissue model to compute therefrom a deep-layer-specific absorption property corresponding to the relatively deep tissue layer.
摘要翻译：描述了用于非侵入式分光光度监测具有多个组织层的生物体积的方法，系统和相关的计算机程序产品。测量沿着生物体积的表面的多个预定的源 - 检测器分离距离中的每一个的聚集吸收和散射性质，该测量基于生物体积的模型作为单层，半无限均质体积。检索预定的多层组织模型，其表征（a）多层组织结构的每层的吸收和散射性质之间的数学关系，以及（b）多层组织结构的聚集吸收和散射性质作为将沿着其表面的选定的源 - 检测器间隔距离测量。测量的聚集体吸收和散射性质与预定的多层组织模型结合进行处理，从而计算对应于相对较深的组织层的深层特异性吸收特性。

2. 发明申请

US20080253231A1 FUNCTIONAL ACTUATOR-SENSOR PATH OPTIMIZATION IN STRUCTURAL HEALTH MONITORING SYSTEM 有权
标题翻译：结构健康监测系统中功能执行器 - 传感器路径优化
公开(公告)号：US20080253231A1
公开(公告)日：2008-10-16
申请号：US12103562
申请日：2008-04-15
申请人： Zengpin Yu , Bao Liu , Shawn J. Beard , David C. Zhang
发明人： Zengpin Yu , Bao Liu , Shawn J. Beard , David C. Zhang
IPC分类号： H04B11/00
CPC分类号： G01N29/041 , G01N29/36 , G01N29/4463 , G01N2291/0427 , G01N2291/106
摘要： A method for optimizing transducer performance in an array of transducers in a structural health monitoring system includes specifying a plurality of paths between pairs of the transducers on a monitored structure and evaluating the quality of signal transmissions along the paths so as to optimize the gain and frequency operating condition of the transducers.
摘要翻译：用于优化结构健康监测系统中的换能器阵列中的换能器性能的方法包括在被监测的结构上指定成对的换能器之间的多个路径并且评估沿着路径的信号传输的质量，以便优化增益和频率传感器的工作状态。

3. 发明申请

US20080155357A1 Structural health monitoring network 审中-公开
标题翻译：结构健康监测网络
公开(公告)号：US20080155357A1
公开(公告)日：2008-06-26
申请号：US11543185
申请日：2006-10-03
申请人： Zengpin Yu , Chang Zhang , Irene Li
发明人： Zengpin Yu , Chang Zhang , Irene Li
IPC分类号： G06F11/00
CPC分类号： G05B23/0213
摘要： A networked configuration of structural health monitoring elements. Monitoring elements such as sensors and actuators are configured as a network, with groups of monitoring elements each controlled by a local controller, or cluster controller. A data bus interconnects each cluster controller with a router, forming a networked group of “monitoring clusters” connected to a router. In some embodiments, the router identifies particular clusters, and sends commands to the appropriate cluster controllers, instructing them to carry out the appropriate monitoring operations. In turn, the cluster controllers identify certain ones of their monitoring elements, and direct them to monitor the structure as necessary. Data returned from the monitoring elements is sent to the cluster controllers, which then pass the information to the router.
摘要翻译：结构健康监测元素的联网配置。诸如传感器和执行器之类的监控元件被配置为网络，各组监视元件各自由本地控制器或集群控制器控制。数据总线将每个集群控制器与路由器互连，形成连接到路由器的联网组“监控集群”。在一些实施例中，路由器识别特定的集群，并向适当的集群控制器发送命令，指示它们执行适当的监视操作。反过来，集群控制器识别其中的某些监视元素，并指示它们根据需要监视结构。从监控元素返回的数据被发送到集群控制器，然后将这些信息传递给路由器。

4. 发明授权

US06524252B1 Method and system for generating ultrasound frames with decorrelated speckle patterns and generating a compound ultrasound image therefrom 失效
标题翻译：用于产生具有解相关散斑图案的超声波帧并从其产生复合超声图像的方法和系统
公开(公告)号：US06524252B1
公开(公告)日：2003-02-25
申请号：US09721889
申请日：2000-11-24
申请人： Zengpin Yu , Danhua Zhao , Shengtz Lin , Feng Yin
发明人： Zengpin Yu , Danhua Zhao , Shengtz Lin , Feng Yin
IPC分类号： A61B800
CPC分类号： G01S7/52074 , G01S7/52046
摘要： An ultrasound system that generates compound images from component frames having decorrelated speckle patterns. Successive sets of distinct, speckle-affecting parameters are used to generate successive component frames for compounding, and are selected such that the successive component frames have decorrelated speckle patterns. The speckle-affecting parameters that are changed from frame to frame may be selected from a wide variety of parameters, including transmit beamformer parameters, receive beamformer parameters, and demodulator parameters. According to a preferred embodiment, the successive sets of speckle-affecting parameters differ from each other by at least two speckle-affecting parameters. According to another preferred embodiment, the amount by which each of the multiple speckle-affecting parameters is changed is less than a decorrelation threshold for that parameter, that is, by less that the amount that speckle-affecting parameter alone would be required to change in order to yield decorrelated speckle patterns if no other parameters were changed. When more speckle-affecting parameters are changed, each speckle-affecting parameter can be changed by an amount less than its decorrelation threshold, and yet decorrelated speckle patterns can still be obtained. Moreover, because two different types of speckle-affecting parameters tend to alter the spatial resolution of the component frames in different ways, the spatial resolution of the compounded image can be better as compared to the scenario in which only one speckle-affecting parameter is altered by its decorrelation threshold.
摘要翻译：超声系统，其从具有去相关散斑图案的分量帧生成复合图像。连续的不同的，具有斑点影响的参数被用于生成用于复合的连续分量帧，并且被选择成使得连续分量帧具有去相关的散斑图案。从帧到帧改变的斑点影响参数可以从各种参数中选择，包括发射波束形成器参数，接收波束形成器参数和解调器参数。根据优选实施例，连续的斑点影响参数组彼此之间至少有两个斑点影响参数不同。根据另一个优选实施例，多个斑点影响参数中的每一个改变的量小于该参数的去相关阈值，即，少于仅需要改变斑点影响参数的量如果没有其他参数被改变，则产生去相关的斑点图案。当更多的斑点影响参数改变时，每个斑点影响参数可以改变一个小于其去相关阈值的量，然而仍然可以获得去相关的斑点图案。此外，由于两种不同类型的斑点影响参数倾向于以不同的方式改变分量帧的空间分辨率，所以与仅改变一个斑点影响参数的情况相比，复合图像的空间分辨率可以更好通过其去相关阈值。

5. 发明授权

US08317702B2 Full-field breast ultrasound system and architecture 有权
标题翻译：全场乳房超声系统和体系结构
公开(公告)号：US08317702B2
公开(公告)日：2012-11-27
申请号：US10560200
申请日：2004-06-18
申请人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
发明人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
IPC分类号： A61B8/00
CPC分类号： A61B8/4477 , A61B8/0825 , A61B8/4281 , A61B8/4405 , A61B8/5238 , Y10T29/49005
摘要： A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system (202) is modified with an FFBU toolkit to create a dual-capability ultrasound system (200), the dual-capability ultrasound system (200) being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine (112). Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems (202) with FFBU toolkits to quickly create dual-capability ultrasound systems (200).
摘要翻译：描述了在单个系统中提供全场乳房超声（FFBU）功能和通用超声功能的模块化，灵活的架构。传统的通用超声系统（202）用FFBU工具包修改以创建双能力超声系统（200），双能力超声系统（200）能够容纳通用超声功能和FFBU 功能，使用单个超声引擎（112）。除了其他优点之外，现实世界的临床环境可以节省初始系统采购成本，临床楼层节省空间，更便宜和更便宜的系统升级，以及使用单个系统和用户界面进行FFBU筛选和跟踪的功能，诊断，活检等。超声波制造商的观点还有其他优点，即通过使用FFBU工具包修改现有的通用超声波系统（202），通过与FFBU相关的产品快速和/或更容易上市。快速创建双功能超声系统（200）。

6. 发明授权

US08020444B2 Functional actuator-sensor path optimization in structural health monitoring system 有权
标题翻译：结构健康监测系统功能执行器 - 传感器路径优化
公开(公告)号：US08020444B2
公开(公告)日：2011-09-20
申请号：US12103562
申请日：2008-04-15
申请人： Zengpin Yu , Bao Liu , Shawn J. Beard , David C. Zhang
发明人： Zengpin Yu , Bao Liu , Shawn J. Beard , David C. Zhang
IPC分类号： G01N9/24
CPC分类号： G01N29/041 , G01N29/36 , G01N29/4463 , G01N2291/0427 , G01N2291/106
摘要： A method for optimizing transducer performance in an array of transducers in a structural health monitoring system includes specifying a plurality of paths between pairs of the transducers on a monitored structure and evaluating the quality of signal transmissions along the paths so as to optimize the gain and frequency operating condition of the transducers.
摘要翻译：用于优化结构健康监测系统中的换能器阵列中的换能器性能的方法包括在被监测的结构上指定成对的换能器之间的多个路径并且评估沿着路径的信号传输的质量，以便优化增益和频率传感器的工作状态。

7. 发明申请

US20110098566A1 THICK-SLICE ULTRASOUND IMAGES DERIVED FROM ULTRASONIC SCANS OF A CHESTWARDLY-COMPRESSED BREAST OF A SUPINE PATIENT 有权
标题翻译：超声波超声波超声波扫描的厚度超大的超声波扫描仪
公开(公告)号：US20110098566A1
公开(公告)日：2011-04-28
申请号：US12890374
申请日：2010-09-24
申请人： Wei ZHANG , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
发明人： Wei ZHANG , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
IPC分类号： A61B8/14 , G06T15/20
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译：描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。还描述了厚片图像内和书签中心和CAD标记为中心的导航。

8. 发明申请

US20080177163A1 VOLUMETRIC IMAGE FORMATION FROM OPTICAL SCANS OF BIOLOGICAL TISSUE WITH MULTIPLE APPLICATIONS INCLUDING DEEP BRAIN OXYGENATION LEVEL MONITORING 审中-公开
标题翻译：具有包括深层氧化水平监测的多种应用的生物组织的光学扫描的体积图像
公开(公告)号：US20080177163A1
公开(公告)日：2008-07-24
申请号：US12017969
申请日：2008-01-22
申请人： Shih-Ping Wang , Xuefeng Cheng , Zengpin Yu
发明人： Shih-Ping Wang , Xuefeng Cheng , Zengpin Yu
IPC分类号： A61B5/1455
CPC分类号： A61B5/0073 , A61B5/14553 , A61B5/4064 , A61B5/6814 , A61B2562/0233 , A61B2562/046
摘要： Methods, systems, and related computer program products for non-invasive monitoring of a biological volume, such as a human brain, are described. In one preferred embodiment, each of a plurality of optical sources emits optical radiation into the biological volume each of a plurality of optical detectors detects optical radiation impinging thereupon from the biological volume. The optical measurements are processed to compute a requisite property value associated with each source-detector pair. For each source-detector pair, a volumetric basis region corresponding thereto is weighted by the requisite property value, the volumetric basis region being predetermined and representative of an estimated subvolume of the biological volume encountered by optical radiation emitted from that source and propagating to that detector. The weighted volumetric basis regions are accumulated into a volumetric cumulative array, and a display output is generated based at least in part on the volumetric cumulative array.
摘要翻译：描述了用于非侵入性监测生物体积的方法，系统和相关的计算机程序产品，例如人类大脑。在一个优选实施例中，多个光源中的每一个将光辐射发射到生物体积中，多个光学检测器中的每一个检测器从生物体积检测入射的光辐射。处理光学测量以计算与每个源 - 检测器对相关联的必要属性值。对于每个源 - 检测器对，与其对应的体积基础区域由所需的属性值加权，体积基础区域是预定的，并且代表从该源发射并传播到该检测器的光辐射遇到的生物体积的估计子体积。加权体积基础区域被累积到体积累积阵列中，并且至少部分地基于体积累积阵列生成显示输出。

9. 发明授权

US06839762B1 Ultrasound information processing system and ultrasound information exchange protocol therefor 有权
标题翻译：超声信息处理系统及其超声信息交换协议
公开(公告)号：US06839762B1
公开(公告)日：2005-01-04
申请号：US09571197
申请日：2000-05-16
申请人： Zengpin Yu , Shengtz Lin , Eddy Ye , Thomas P. Neff
发明人： Zengpin Yu , Shengtz Lin , Eddy Ye , Thomas P. Neff
IPC分类号： A61B5/0456 , A61B7/04 , A61B8/00 , A61B8/06 , G01S7/52 , G01S15/89 , G06F19/00 , G06F15/16
CPC分类号： A61B5/0456 , A61B7/04 , A61B8/00 , A61B8/06 , A61B8/13 , A61B8/4411 , A61B2560/0271 , G01S7/52025 , G01S7/52034 , G01S15/899 , G06F19/00 , G06F19/321
摘要： An ultrasound information processing system comprises a plurality of ultrasound devices coupled to a high-speed serial ultrasound information bus, wherein each ultrasound device comprises a program for communicating with other ultrasound devices according to an ultrasound information exchange protocol (UIEP). The UIEP is a lightweight, connection-oriented protocol adapted to efficiently transfer ultrasound information among different devices on the ultrasound information bus. Each ultrasound device comprises an application layer program for performing an ultrasound function, as well as a lower protocol layer program for receiving and sending data across the ultrasound information bus according to a high-speed serial bus standard that provides both isochronous and asynchronous data delivery. The ultrasound information exchange protocol (UIEP) program is adapted to receive a communication request from the application layer, open a connection-oriented communication session with the requested ultrasound device, and transfer ultrasound information through the lower protocol layer and across the ultrasound information bus to the requested device. Advantageously, any ultrasound device manufacturer provided with the UIEP program may readily generate application layer code capable of communicating with other manufacturers' ultrasound devices across the ultrasound information bus, without requiring specific knowledge of the internal structure of the other manufacturers' devices or of the specific frame/packet structure of the UIEP/lower layer protocols themselves.
摘要翻译：超声信息处理系统包括耦合到高速串行超声信息总线的多个超声装置，其中每个超声装置包括根据超声信息交换协议（UIEP）与其他超声装置进行通信的程序。 UIEP是一种轻巧的，面向连接的协议，适用于在超声信息总线上的不同设备之间有效传输超声信息。每个超声装置包括用于执行超声功能的应用层程序以及用于根据提供同步和异步数据传送的高速串行总线标准跨超声信息总线接收和发送数据的下层协议层程序。超声信息交换协议（UIEP）程序适于从应用层接收通信请求，打开与所请求的超声设备的面向连接的通信会话，并通过下层协议层和超声信息总线传送超声信息到请求的设备。有利地，提供有UIEP程序的任何超声设备制造商可以容易地生成能够跨越超声信息总线与其他制造商的超声装置进行通信的应用层代码，而不需要对其他制造商的设备的内部结构或具体的 UIEP /下层协议本身的帧/分组结构。

10. 发明授权

US08496586B2 Breast ultrasound examination including scanning through chestwardly compressing membrane and processing and displaying acquired ultrasound image information 有权
标题翻译：胸部超声检查包括通过胸膜压迫膜进行扫描，并处理和显示获取的超声图像信息
公开(公告)号：US08496586B2
公开(公告)日：2013-07-30
申请号：US12760382
申请日：2010-04-14
申请人： Wei Zhang , Jiayu Chen , Thomas P. Neff , Michael E. Reed , Jeanine M. Rader , Douglas G. Summers , Shih-Ping Wang , Tor C. Anderson , Zengpin Yu , Tommy Earl Cupples
发明人： Wei Zhang , Jiayu Chen , Thomas P. Neff , Michael E. Reed , Jeanine M. Rader , Douglas G. Summers , Shih-Ping Wang , Tor C. Anderson , Zengpin Yu , Tommy Earl Cupples
IPC分类号： A61B8/00
CPC分类号： A61B8/0825 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/469 , A61B8/483 , A61B8/5238 , A61B8/565
摘要： Navigation among breast ultrasound volumes derived from different volumetric ultrasonic scans of a same breast is described. On a display of a breast ultrasound workstation, a first image derived from a first ultrasonic volume is displayed. A user election of a source region of interest (ROI) in the first image is received. A destination ROI within a second ultrasonic volume is identified that at least roughly corresponds to a same locality of tissue in the breast as the source ROI. A second image derived from the second ultrasonic volume and including the destination ROI is displayed, the destination ROI being highlighted.
摘要翻译：描述从相同乳房的不同体积超声波扫描得到的乳房超声体积之间的导航。在乳房超声工作站的显示器上，显示从第一超声波体积得到的第一图像。接收用户选择第一图像中的感兴趣的源区域（ROI）。识别出在第二超声波体积内的目的地ROI至少大致对应于乳房中与源ROI相同的局部区域。显示从第二超声波体积导出并包括目的地ROI的第二图像，目的地ROI被突出显示。

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