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1. 发明申请

US20120289841A1 APPARATUS AND CALIBRATION METHOD FOR BLOOD PRESSURE MEASUREMENT 审中-公开
标题翻译：用于血压测量的装置和校准方法
公开(公告)号：US20120289841A1
公开(公告)日：2012-11-15
申请号：US13511555
申请日：2009-12-01
申请人： Yunquan Chen , Yun Xu
发明人： Yunquan Chen , Yun Xu
IPC分类号： A61B5/022
CPC分类号： A61B5/022 , A61B2560/0238
摘要： Apparatus and a calibration method for measurement of blood pressure are used to determine personal PIP's for a given subject and to store the personal PIP's for future personal use in blood pressure measurement in the subject. The apparatus comprises at least one button communicating with a MPU unit for entering information used to determine the personal PIP's of the subject. The method comprises the steps of obtaining information required to determining the PIP's of a subject, determining the personal PIP's of the subject, and storing the personal PIP's of the subject for future personal use for the subject.
摘要翻译：用于测量血压的装置和校准方法用于确定给定受试者的个人PIP，并存储个人PIP以供将来个人使用在受试者的血压测量中。该装置包括与MPU单元通信的至少一个按钮，用于输入用于确定对象的个人PIP的信息。该方法包括以下步骤：获得确定受试者的PIP所需的信息，确定受试者的个人PIP，以及存储受试者的个人PIP的未来个人用于受试者。

2. 发明申请

US20110092830A1 METHOD FOR AUTOMATIC ERROR DETECTION IN PRESSURE MEASUREMENT AND AN ELECTRONIC SPHYGMOMANOMETER 审中-公开
标题翻译：压力测量中自动检测误差的方法和电子气象仪
公开(公告)号：US20110092830A1
公开(公告)日：2011-04-21
申请号：US12994903
申请日：2009-05-27
申请人： Yunquan Chen , Yun Xu
发明人： Yunquan Chen , Yun Xu
IPC分类号： A61B5/022 , G06F19/00 , G01L27/00
CPC分类号： A61B5/0225 , A61B2560/0223 , A61B2560/0276
摘要： This invention discloses a method for automatic error detection in pressure measurement and an electronic sphygmomanometer using the method. The electronic sphygmomanometer comprises two pressure sensing circuits connected to a MPU. The first pressure sensing circuit is normally-on in pressure measurement. The second pressure sensing circuit is normally-off in pressure measurement. Said normally-off pressure sensing circuit is periodically turned on in an automatic manner to measure the same pressure as the normally-on pressure sensing circuit is used to measure. Said MPU computes the difference between the pressures obtained from the two pressure sensing circuits. When the difference is greater than a given error limit, calibration error warning will be given.
摘要翻译：本发明公开了一种使用该方法的压力测量中的自动误差检测方法和电子血压计。电子血压计包括连接到MPU的两个压力感测电路。第一压力检测电路通常在压力测量中。第二压力检测电路在压力测量中是常态的。所述常闭压力检测电路以自动方式周期性地接通以测量与常压压力感测电路用于测量相同的压力。所述MPU计算从两个压力感测电路获得的压力之间的差。当差异大于给定的误差极限时，将给出校准错误警告。

3. 发明授权

US06599251B2 Continuous non-invasive blood pressure monitoring method and apparatus 有权
标题翻译：连续非侵入性血压监测方法及装置
公开(公告)号：US06599251B2
公开(公告)日：2003-07-29
申请号：US09917279
申请日：2001-07-27
申请人： Yunquan Chen , Luya Li , Cecil Hershler , Ryan Peter Dill
发明人： Yunquan Chen , Luya Li , Cecil Hershler , Ryan Peter Dill
IPC分类号： A61B502
CPC分类号： A61B5/4884 , A61B5/021 , A61B5/02125 , A61B5/02255 , A61B5/0285 , A61B5/7278
摘要： A non-invasive apparatus and method for monitoring the blood pressure of a subject detects a pulse signal at both a first and second location on the subject's body. The elapsed time between the arrival of corresponding points of the pulse signal at the first and second locations is determined. Blood pressure is related to the elapsed time by relationships such as: P=a+b ln(T) where a and b are constants dependent upon the nature of the subject and the signal detecting devices. The system can be calibrated by measuring a single pair of reference blood pressure and corresponding elapsed time.
摘要翻译：用于监测被检者的血压的非侵入性装置和方法在被检体的第一和第二位置检测脉搏信号。确定在第一和第二位置处的脉冲信号的相应点到达之间的经过时间。血压与经过的时间有关，例如：其中a和b是取决于受试者的性质和信号检测装置的常数。可以通过测量一对参考血压和相应的经过时间来校准系统。

4. 发明授权

US06503206B1 Apparatus having redundant sensors for continuous monitoring of vital signs and related methods 有权
标题翻译：具有用于连续监测生命体征和相关方法的冗余传感器的装置
公开(公告)号：US06503206B1
公开(公告)日：2003-01-07
申请号：US09917608
申请日：2001-07-27
申请人： Luya Li , Yunquan Chen , Rakesh Kumar Sethi , Ming Sun
发明人： Luya Li , Yunquan Chen , Rakesh Kumar Sethi , Ming Sun
IPC分类号： A61B502
CPC分类号： A61B5/02125 , A61B5/0205 , A61B5/024 , A61B5/1455
摘要： Apparatus for monitoring one or more vital signs of a subject has a number of sensors. There is at least one redundant sensor. Each sensor originates a signal. A selection system determines performance criteria for a number of groups of signals. Each group includes one or more signals. The apparatus computes a predicted value for a vital sign by either computing a value from each group of signals and taking a weighted average with weights based upon the performance criterion or by selecting one of the groups of signals for which the performance criterion is best and computing the output value from that group of signals. The output values are relatively insensitive to artifacts and to errors caused by the disconnection or malfunctioning of one sensor.
摘要翻译：用于监测受试者的一个或多个生命体征的装置具有多个传感器。至少有一个冗余传感器。每个传感器产生一个信号。选择系统确定多组信号的性能标准。每组包括一个或多个信号。该装置通过计算来自每组信号的值并且基于性能标准采取具有权重的加权平均值或通过选择性能标准最佳的信号组中的一个来计算生命体征的预测值，并且计算来自该组信号的输出值。输出值对于伪影和由一个传感器的断开或故障引起的错误相对不敏感。

5. 发明授权

US5299572A Biological electrode array 失效
标题翻译：生物电极阵列
公开(公告)号：US5299572A
公开(公告)日：1994-04-05
申请号：US969458
申请日：1992-10-30
申请人： Yunquan Chen , Charles A. Laszlo , Cecil Hershler
发明人： Yunquan Chen , Charles A. Laszlo , Cecil Hershler
IPC分类号： A61B5/04 , A61B5/0408 , A61B5/0492
CPC分类号： A61B5/04004 , A61B5/04085 , A61B5/0492
摘要： A biological electrode array connects electrical apparatuses to the skin surface of a living body. The array includes an insulating mount having a central area. A case is connected to the mount and has a cavity with conductive shielding extending thereabout. A plurality of shielding electrodes extend from the insulating mount and are spaced-apart about the central area. The shielding electrodes are electrically connected to the shielding of the case. A plurality of spaced-apart brush-tip electrodes extend from the central area of the mount. Signal buffers within the cavity of the case are electrically connected to the brush-tip electrodes. Conductors extend from the cavity, each conductor being electrically connected to one of the buffers. The brush-tip electrodes have thin, but resilient wires, typically of hard stainless steel or tungsten.
摘要翻译：生物电极阵列将电气设备连接到生物体的皮肤表面。阵列包括具有中心区域的绝缘安装座。壳体连接到安装座，并且具有在其周围延伸的导电屏蔽的腔体。多个屏蔽电极从绝缘安装座延伸并围绕中心区域间隔开。屏蔽电极与壳体的屏蔽电连接。多个间隔开的刷尖电极从安装座的中心区域延伸。壳体腔内的信号缓冲器电连接到刷尖电极。导体从空腔延伸，每个导体电连接到缓冲器之一。刷尖电极具有薄但弹性的线，通常为硬质不锈钢或钨。

6. 发明申请

US20060247541A1 Non-toxic liquid column sphygmomanometer 失效
标题翻译：无毒液柱血压计
公开(公告)号：US20060247541A1
公开(公告)日：2006-11-02
申请号：US11118427
申请日：2005-05-02
申请人： Yunquan Chen , Jian Liu
发明人： Yunquan Chen , Jian Liu
IPC分类号： A61B5/02
CPC分类号： A61B5/023 , A61B5/0235
摘要： A sphygmomanometer having an elongated tube, an air chamber coupled to a first end of the tube, and a liquid chamber coupled to a second end of the tube. The liquid chamber is partially filled with fluid and is couplable to a source of external pressure. An offset region located proximate the second end of the tube has a significantly reduced cross-sectional area so as to reduce the effect of fluid level changes on pressure measurement accuracy. At least one ventilation valve is coupled to the elongated tube and the air chamber and is operative to vent the elongated tube and the air chamber to atmosphere.
摘要翻译：血压计具有细长管，联接到管的第一端的空气室和联接到管的第二端的液体室。液体室部分地填充有流体，并且可连接到外部压力源。位于管的第二端附近的偏移区域具有显着减小的横截面面积，以便降低液位变化对压力测量精度的影响。至少一个通风阀连接到细长管和空气室，并且可操作地将细长管和空气室排放到大气中。

7. 发明申请

US20060191675A1 APPARATUS AND METHODS FOR WARMING AND COOLING BODIES 审中-公开
标题翻译：装置和冷却装置的方法
公开(公告)号：US20060191675A1
公开(公告)日：2006-08-31
申请号：US11277078
申请日：2006-03-21
申请人： R. FLETCHER , John Fletcher , Katie Au , Christopher Clarke , Yunquan Chen
发明人： R. FLETCHER , John Fletcher , Katie Au , Christopher Clarke , Yunquan Chen
IPC分类号： F28F1/10
CPC分类号： F28F3/022 , F28F3/12
摘要： A flexible heat exchanger is suitable for heating or cooling living subjects or objects. The heat exchanger has a volume having at least one inlet for receiving a heat exchange fluid and at least one outlet. A flexible heat exchange plate that is essentially impermeable to the heat exchange fluid is penetrated by substantially rigid thermally-conductive members. The members provide paths of high thermal conductivity through the plate. The heat exchange fluid may be water.
摘要翻译：柔性热交换器适用于加热或冷却活体或物体。热交换器具有至少一个用于接收热交换流体和至少一个出口的入口的体积。基本上不可渗透热交换流体的柔性热交换板被基本刚性的导热构件穿透。这些构件通过板提供高导热性的路径。热交换流体可以是水。

8. 发明授权

US06719703B2 Method and apparatus for measuring blood pressure by the oscillometric technique 有权
标题翻译：通过示波技术测量血压的方法和装置
公开(公告)号：US06719703B2
公开(公告)日：2004-04-13
申请号：US09882908
申请日：2001-06-15
申请人： Yunquan Chen , Anton Bogdan Zorn , Kevin Daryl Strange
发明人： Yunquan Chen , Anton Bogdan Zorn , Kevin Daryl Strange
IPC分类号： A61B502
CPC分类号： A61B5/02225 , A61B5/022
摘要： A method and apparatus for measuring blood pressure by the oscillometric technique. The method incorporates variable PIP's. The method comprises the steps of obtaining a value for the peak amplitude Amax of an oscillometric envelope; determining a cuff pressure, CP, which corresponds in time with Amax, this pressure representing the MAP of the subject; computing a variable value PIPSBP as a function of MAP; performing the calculation Asbp=Amax*PIPSBP to determine a systolic amplitude value Asbp along the oscillometric envelope; and determining the cuff pressure C which corresponds in time to Asbp, this value representing the systolic blood pressure (SBP) of the subject. PIP can be calculated using a piece-wise linear, polynomial, exponential or other function.
摘要翻译：一种通过示波技术测量血压的方法和装置。该方法结合了可变PIP。该方法包括以下步骤：获得示波包络的峰值振幅Amax的值; 确定袖珍压力CP，其与Amax在时间上对应，该压力表示受试者的MAP; 计算作为MAP的函数的可变值PIPSBP; 执行计算Asbp = Amax * PIPSBP以确定沿示波包络的收缩幅值Asbp; 以及确定在时间上对应于Asbp的袖带压力C，该值表示被检体的收缩压（SBP）。 PIP可以使用分段线性，多项式，指数或其他函数来计算。

9. 发明授权

US5824027A Nerve cuff having one or more isolated chambers 失效
标题翻译：神经袖带有一个或多个隔离室
公开(公告)号：US5824027A
公开(公告)日：1998-10-20
申请号：US911604
申请日：1997-08-14
申请人： Joaquin Andreas Hoffer , Yunquan Chen , Kevin D. Strange , Paul Richard Christensen
发明人： Joaquin Andreas Hoffer , Yunquan Chen , Kevin D. Strange , Paul Richard Christensen
IPC分类号： A61N1/05
CPC分类号： A61N1/0556
摘要： A nerve cuff has one or more sets of electrodes for selectively recording electrical activity in a nerve or for selectively stimulating regions of the nerve. Each set of electrodes is located in a longitudinally extending chamber between a pair of longitudinal ridges which project into the bore of the nerve cuff. The ridges are electrically insulating and serve to improve the selectivity of the nerve cuff. The ridges seal against an outer surface of the nerve without penetrating the nerve. Nerve cuffs according to the invention may be used in functional electrical stimulation systems. Electrodes may be replaced with fine tubes to enable pharmacological agents to be delivered selectively through the tubes to portions of a nerve passing through the cuff or to permit the sampling of fluids from regions adjacent selected outer portions of the nerve. The nerve cuff may be constructed of modular segments which can be selected to provide a customized fit to the shape and size of a nerve at time of implantation.
摘要翻译：神经箍具有一组或多组电极，用于选择性地记录神经中的电活动或用于选择性地刺激神经的区域。每组电极位于一对纵向脊之间的纵向延伸室中，该纵向脊突出到神经箍的孔中。脊是电绝缘的，用于提高神经袖带的选择性。脊部不会穿透神经而密封神经的外表面。根据本发明的神经袖口可用于功能性电刺激系统。可以用细管替代电极，以使药物选择性地通过管递送到穿过袖带的神经的部分，或允许从与神经选定的外部部分相邻的区域取样流体。神经箍可以由可以选择以在植入时为神经的形状和尺寸进行定制配合的模块化段构成。

10. 发明授权

US5443559A Brush-tip electrode 失效
标题翻译：刷尖电极
公开(公告)号：US5443559A
公开(公告)日：1995-08-22
申请号：US156732
申请日：1993-11-24
申请人： Yunquan Chen , Charles A. Laszlo , Cecil Hershler
发明人： Yunquan Chen , Charles A. Laszlo , Cecil Hershler
IPC分类号： A61B5/04 , A61B5/0408 , A61B5/0492
CPC分类号： A61B5/04004 , A61B5/04085 , A61B5/0492 , A61B2562/182
摘要： An electrode is used the connecting apparatuses to the skin surface of a living body. It includes a tube having an end and a plurality of hard, resilient wires extending outwardly from the end of the tube. The wires have splayed ends in a brush-tip-like arrangement having an end formed by the spaced-apart wires which is multi-pointed and abrasive.
摘要翻译：将电极用于与生物体的皮肤表面的连接装置。它包括具有端部的管和从管的端部向外延伸的多个硬的弹性线。电线已经以刷尖形布置的端部展开，其端部由多边形和磨料的间隔开的线形成。

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