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1. 发明授权

US07563493B2 Ink jet recording medium, method of ink jet image formation and photographic print 失效
标题翻译：喷墨记录介质，喷墨图像形成方法和照相印刷
公开(公告)号：US07563493B2
公开(公告)日：2009-07-21
申请号：US10502720
申请日：2003-11-28
申请人： Satoru Shinohara , Masanobu Hida , Yumiko Nagano
发明人： Satoru Shinohara , Masanobu Hida , Yumiko Nagano
IPC分类号： B41M5/50
CPC分类号： B41M7/0027 , B41M5/504 , B41M5/508
摘要： An inkjet-recording medium has excellent various preservabilities, for example, the lightfastness of an image, resistance to bleeding under high-temperature and high-humidity conditions, and resistance to indoor fading and discoloration when a surface of a printing paper is subjected to laminating treatment. In an inkjet-recording medium having an ink-receiving layer on one surface of a base, the base having abilities to absorb and retain an ink solvent, a low oxygen-permeable resin layer preferably having an oxygen permeability of 10 cc/(m2·D·atm) at a temperature of 20° C. and at a relative humidity of 90% is provided on another surface of the base.
摘要翻译：喷墨记录介质具有优异的各种保存性，例如图像的耐光性，耐高温和高湿度条件下的渗色性，以及当打印纸的表面经历层压时耐室内褪色和变色治疗。在具有在基体的一个表面上的油墨接收层的喷墨记录介质中，该基体具有吸收和保持油墨溶剂的能力，优选具有10cc /（m 2）的透氧性的低透氧性树脂层。在20℃的温度和90％的相对湿度下设置在基底的另一个表面上。

2. 发明申请

US20070190271A1 Inkjet-Recording Medium 审中-公开
标题翻译：喷墨记录介质
公开(公告)号：US20070190271A1
公开(公告)日：2007-08-16
申请号：US11739583
申请日：2007-04-24
申请人： Satoru SHINOHARA , Masanobu Hida , Yumiko Nagano
发明人： Satoru SHINOHARA , Masanobu Hida , Yumiko Nagano
IPC分类号： B41M5/00
CPC分类号： B41M7/0027 , B41M5/504 , B41M5/508
摘要： An inkjet-recording medium has excellent various preservabilities, for example, the lightfastness of an image, resistance to bleeding under high-temperature and high-humidity conditions, and resistance to indoor fading and discoloration when a surface of a printing paper is subjected to laminating treatment. In an inkjet-recording medium having an ink-receiving layer on one surface of a base, the base having abilities to absorb and retain an ink solvent, a low oxygen-permeable resin layer preferably having an oxygen permeability of 10 cc/(m2·D·atm) at a temperature of 20° C. and at a relative humidity of 90% is provided on another surface of the base.
摘要翻译：喷墨记录介质具有优异的各种保存性，例如图像的耐光性，耐高温和高湿度条件下的渗色性，以及当打印纸的表面经历层压时耐室内褪色和变色治疗。在具有在基底的一个表面上的油墨接受层的喷墨记录介质中，该基体具有吸收和保持油墨溶剂的能力，优选具有10cc /（m 2）的透氧性的低透氧性树脂层，在20℃的温度和90％的相对湿度下，在基底的另一个表面上设置SUP> 2 .D.atm）。

3. 发明申请

US20050078162A1 Ink jet recording medium, method of ink jet image formation and photographic print 失效
标题翻译：喷墨记录介质，喷墨图像形成方法和照相印刷
公开(公告)号：US20050078162A1
公开(公告)日：2005-04-14
申请号：US10502720
申请日：2003-11-28
申请人： Satoru Shinohara , Masanobu Hida , Yumiko Nagano
发明人： Satoru Shinohara , Masanobu Hida , Yumiko Nagano
IPC分类号： B41J2/01 , B41M5/00 , B41M5/50 , B41M5/52 , B41M7/00
CPC分类号： B41M7/0027 , B41M5/504 , B41M5/508
摘要： An inkjet-recording medium has excellent various preservabilities, for example, the lightfastness of an image, resistance to bleeding under high-temperature and high-humidity conditions, and resistance to indoor fading and discoloration when a surface of a printing paper is subjected to laminating treatment. In an inkjet-recording medium having an ink-receiving layer on one surface of a base, the base having abilities to absorb and retain an ink solvent, a low oxygen-permeable resin layer preferably having an oxygen permeability of 10 cc/(m2·D·atm) at a temperature of 20° C. and at a relative humidity of 90% is provided on another surface of the base.
摘要翻译：喷墨记录介质具有优异的各种保存性，例如图像的耐光性，耐高温和高湿度条件下的渗色性，以及当打印纸的表面经历层压时耐室内褪色和变色治疗。在具有在基底的一个表面上的油墨接受层的喷墨记录介质中，该基体具有吸收和保持油墨溶剂的能力，优选具有10cc /（m 2）的透氧性的低透氧性树脂层， 2℃，温度为20℃，相对湿度为90％时，设置在基底的另一个表面上。

4. 发明授权

US5856303A Peptide, a bronchus-expanding agent, and a blood-flow-improving agent 失效
标题翻译：肽，支气管扩张剂和血液流动改善剂
公开(公告)号：US5856303A
公开(公告)日：1999-01-05
申请号：US776815
申请日：1997-02-07
申请人： Kazuhisa Kashimoto , Yumiko Nagano
发明人： Kazuhisa Kashimoto , Yumiko Nagano
IPC分类号： A61K38/00 , A61P7/00 , C07K14/575 , C07K14/605 , C07K5/00 , C07K7/00
CPC分类号： C07K14/605 , C07K14/575 , C07K14/57563 , A61K38/00
摘要： The present invention relates to a peptide represented by the general formula (1): ##STR1## wherein A is Ala or Gly; B is Ile or Val; C is Asn or Ser; D is Thr or Ser; E is Leu or Tyr; each of F, I and J is Lys or Arg, and at least one of F, I and J is Arg; G is Met, Leu or Nle; K is Asn or Ala; L is Ser or Ala; M is Ile or Val; and N is --NH.sub.2 or Asn--NH.sub.2, excluding the combination where A is Ala, B is Val, C is Asn, D is Thr, E is Leu, K is Asn, L is Ser, M is Ile, and N is Asn--NH.sub.2, and pharmaceutically acceptable salts thereof, as well as to a bronchus-expanding agent or a blood-flow-improving agent comprising said peptide or a pharmaceutically acceptable salt thereof as an active ingredient.
摘要翻译： PCT No.PCT / JP96 / 01543 Sec。 371日期1997年2月7日 102（e）1997年2月7日PCT PCT 1996年6月6日PCT公布。出版物WO96 / 41814 PCT 日期：1996年12月27日本发明涉及由通式（1）表示的肽：HHisSerAspABPheThrAspCTyrD（1）ArgEArgFGlnGAlaValIJTyrLeuKLMLeuN其中A为Ala或Gly; B是Ile或Val; C是Asn或Ser; D是Thr或Ser; E是Leu或Tyr; F，I和J各自为Lys或Arg，F，I和J中的至少一个为Arg; G为Met，Leu或Nle; K为Asn或Ala; L是Ser或Ala; M是Ile或Val; N为-NH 2或Asn-NH 2，不包括A为Ala的组合，B为Val，C为Asn，D为Thr，E为Leu，K为Asn，L为Ser，M为Ile，N为Asn -NH 2及其药学上可接受的盐，以及包含所述肽或其药学上可接受的盐作为活性成分的支气管扩张剂或血液流动改进剂。

5. 发明授权

US06448031B1 Process for producing LH-RH derivatives 失效
标题翻译：生产LH-RH衍生物的方法
公开(公告)号：US06448031B1
公开(公告)日：2002-09-10
申请号：US09463947
申请日：2000-02-04
申请人： Kazuhisa Kashimoto , Yumiko Nagano , Akiko Ohata
发明人： Kazuhisa Kashimoto , Yumiko Nagano , Akiko Ohata
IPC分类号： C12P2106
CPC分类号： C07K5/0825 , C07K7/23
摘要： This invention relates to a method for producing an LH-RH derivative, characterized in that a peptide fragment shown by general formula (1): pGlu-His-Trp-OR1 (where R1 denotes a lower alkyl) and a peptide fragment shown by general formula (2): H-Ser-Tyr-X-Leu-Arg-Pro-Y (where X denotes an amino acid selected from the group consisting of D-amino acids such as D-Leu, D-Ser(But), D-Trp, and (2-napthyl)-D-Ala, and Gly, and Y denotes Gly-NH2, Azgly(Azaglycine)-NH2 or NHR2 (R2 is lower alkyl)) are allowed to react in the presence of chymotrypsin or a chymotrypsin-like enzymes, to produce the LH-RH derivative shown by general formula (3): pGlu-His-Trp-Ser-Tyr-X-Leu-Arg-Pro-Y (where X and Y are as defined above). Since the method does not accompany a side reaction such as racemization, it enables simple separation and purification of LH-RH derivatives. Moreover the method enables to provide high yields, as well as recovery and recycling of unreacted peptide fragments, therefore it is valuable in industrial use.
摘要翻译：本发明涉及一种LH-RH衍生物的制造方法，其特征在于，通式（1）表示的肽片段：pGlu-His-Trp-OR1（其中R1表示低级烷基）和通式式（2）：H-Ser-Tyr-X-Leu-Arg-Pro-Y（其中X表示选自D-氨基酸如D-Leu，D-Ser（But）， D-Trp和（2-萘基）-D-Ala，Gly和Y表示Gly-NH2，Azgly（Azaglycine）-NH2或NHR2（R2是低级烷基））在糜蛋白酶或（3）所示的LH-RH衍生物：pGlu-His-Trp-Ser-Tyr-X-Leu-Arg-Pro-Y（其中X和Y如上定义）。由于该方法不伴随诸如外消旋化的副反应，因此能够简单地分离和纯化LH-RH衍生物。此外，该方法能够提供高产率，以及未反应的肽片段的回收和再循环，因此它在工业上是有价值的。

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