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1. 发明申请

WO2006052722A1 GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF 审中-公开
标题翻译： GLYCOGEN PHOSPHORYLASE抑制剂化合物及其药物组合物
公开(公告)号：WO2006052722A1
公开(公告)日：2006-05-18
申请号：PCT/US2005/039956
申请日：2005-11-04
申请人： SMITHKLINE BEECHAM CORPORATION , EVANS, Karen , CICHY-KNIGHT, Maria , COPPO, Frank, Teen , DWORNIK, Kate, Ann , GALE, Jennifer, Paul , GARRIDO, Dulce, Maria , LI, Yue, Hu , PATEL, Mehul, P. , TAVARES, Francis X , THOMSON, Stephen, Andrew , DICKERSON, Scott, Howard , PEAT, Andrew, James , SPARKS, Steven, Meagher , BANKER, Pierette , COOPER, Joel, P.
发明人： EVANS, Karen , CICHY-KNIGHT, Maria , COPPO, Frank, Teen , DWORNIK, Kate, Ann , GALE, Jennifer, Paul , GARRIDO, Dulce, Maria , LI, Yue, Hu , PATEL, Mehul, P. , TAVARES, Francis X , THOMSON, Stephen, Andrew , DICKERSON, Scott, Howard , PEAT, Andrew, James , SPARKS, Steven, Meagher , BANKER, Pierette , COOPER, Joel, P.
IPC分类号： C07C275/28 , C07C275/30 , C07C273/18 , C07C233/87 , C07D221/08 , C07D213/82 , C07D333/38 , A61K31/17 , A61P3/10
CPC分类号： C07C275/42 , C07C237/42 , C07C323/59 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/08 , C07D207/16 , C07D209/20 , C07D211/34 , C07D211/56 , C07D211/66 , C07D211/78 , C07D213/56 , C07D213/82 , C07D233/64 , C07D239/26 , C07D261/08 , C07D261/14 , C07D277/56 , C07D307/68 , C07D307/79 , C07D309/14 , C07D317/50 , C07D319/18 , C07D333/24 , C07D333/38 , C07D333/68 , C07D333/70 , C07D335/02 , C07D409/04
摘要： The invention relates to glycogen phosphorylase inhibitor compounds, pharmaceutical compositions of these compounds, methods of treatment using the pharmaceutical compositions to treat diabetes, conditions associated with diabetes, and/or tissue ischemia, including myocardial ischemia, and processes for making the compounds.
摘要翻译：本发明涉及糖原磷酸化酶抑制剂化合物，这些化合物的药物组合物，使用药物组合物治疗糖尿病的方法，与糖尿病有关的病症和/或组织缺血，包括心肌缺血，以及制备该化合物的方法。

2. 发明申请

WO2005058376A1 POLYMERIC MICELLAR COMPLEXES AND DRUG DELIVERY VEHICLES THEREOF 审中-公开
标题翻译：聚合物麦芽糖复合物和药物递送车辆
公开(公告)号：WO2005058376A1
公开(公告)日：2005-06-30
申请号：PCT/US2004/042768
申请日：2004-12-17
申请人： SMITHKLINE BEECHAM CORPORATION , IGNATIOUS, Francis , LI, Yue, Hu
发明人： IGNATIOUS, Francis , LI, Yue, Hu
IPC分类号： A61K51/00
CPC分类号： A61K9/1075 , A61K31/4745 , A61K31/7024 , A61K31/704 , A61K31/77 , A61K47/593 , A61K47/60 , A61K47/6907 , A61K47/6921
摘要： Disclosed are complexes of an amphiphilic copolymer, wherein the amphiphilic copolymer has benzoyl sulfonic acid groups on the hydrophobic segment of the copolymer.
摘要翻译：公开了两亲共聚物的络合物，其中两亲共聚物在共聚物的疏水链段上具有苯甲酰基磺酸基团。

3. 发明申请

WO2004053087A3 NF-KappaB INHIBITORS 审中-公开
标题翻译： NF-κB抑制剂
公开(公告)号：WO2004053087A3
公开(公告)日：2004-09-10
申请号：PCT/US0338970
申请日：2003-12-05
申请人： SMITHKLINE BEECHAM CORP , CALLAHAN JAMES FRANCES , LI YUE HU
发明人： CALLAHAN JAMES FRANCES , LI YUE HU
IPC分类号： A61K31/381 , C07D333/38 , C07D333/36 , A61K31/38
CPC分类号： A61K31/381 , C07D333/38
摘要： The present invention provides a specific compound and methods for treating diseases related to the inhibition of IKK-beta phosphorylation of Ikappa.
摘要翻译：本发明提供了具体化合物和治疗与抑制Ikappa的IKK-β磷酸化有关的疾病的方法。

4. 发明申请

WO2004053087A2 NF-ΚB INHIBITORS 审中-公开
标题翻译： NF-κB抑制剂
公开(公告)号：WO2004053087A2
公开(公告)日：2004-06-24
申请号：PCT/US2003/038970
申请日：2003-12-05
申请人： SMITHKLINE BEECHAM CORPORATION , CALLAHAN, James, Frances , LI, Yue, Hu
发明人： CALLAHAN, James, Frances , LI, Yue, Hu
IPC分类号： C12N
CPC分类号： A61K31/381 , C07D333/38
摘要： The present invention provides a specific compound and methods for treating diseases related to the inhibition of IKK-β phosphorylation of Iκ.
摘要翻译：本发明提供了用于治疗与抑制Iκ的IKK-β磷酸化有关的疾病的具体化合物和方法。

5. 发明申请

US20230096334A1 PROVIDING A REPLY INTERFACE FOR A MEDIA CONTENT ITEM WITHIN A MESSAGING SYSTEM 有权
公开(公告)号：US20230096334A1
公开(公告)日：2023-03-30
申请号：US17936173
申请日：2022-09-28
申请人： Newar Husam Al Majid , Alex Beltyukov , Nathan Kenneth Boyd , Jacob Catalano , Wenbin Chen , Matthew Lee Cook , Andrew Grosvenor Cooper , Zuoyou Gu , Yue Hu , Timothy Kautz , Edward Koai , Karen Jong-Hwi Lee , Chinmay Lonkar , Lu Lu , Zachary Lupei , Charles Melbye , Celia Nicole Mourkogiannis , Chiung-Fu Shih , Brian Yee , Jiawen Zeng , Dongguang Zhao
发明人： Newar Husam Al Majid , Alex Beltyukov , Nathan Kenneth Boyd , Jacob Catalano , Wenbin Chen , Matthew Lee Cook , Andrew Grosvenor Cooper , Zuoyou Gu , Yue Hu , Timothy Kautz , Edward Koai , Karen Jong-Hwi Lee , Chinmay Lonkar , Lu Lu , Zachary Lupei , Charles Melbye , Celia Nicole Mourkogiannis , Chiung-Fu Shih , Brian Yee , Jiawen Zeng , Dongguang Zhao
IPC分类号： G06F3/04883 , G06F3/0484 , H04L51/21
摘要： Aspects of the present disclosure involve a system comprising a computer-readable storage medium storing a program and method for providing a reply interface for a media content item within a messaging system. The program and method provide for receiving, by a messaging application, first user input corresponding to a request for a content feed, the content feed comprising a plurality of media content items; providing, in response to receiving the first user input, for display of the content feed; receiving, by the messaging application, second user input of a swipe gesture performed with respect to display of a media content item of the plurality of media content items; and providing, in response to receiving the second user input, for display of a reply interface together with display of the media content item, the reply interface for sending a reply message to a user associated with the media content item.

6. 发明申请

US20050165087A1 Nf-kb inhibitors 失效
标题翻译： Nf-kb抑制剂
公开(公告)号：US20050165087A1
公开(公告)日：2005-07-28
申请号：US10516836
申请日：2003-05-29
申请人： James Callahan , Yue Hu Li
发明人： James Callahan , Yue Hu Li
IPC分类号： A61K31/381 , A61P1/04 , A61P3/10 , A61P7/00 , A61P9/10 , A61P11/06 , A61P13/12 , A61P17/02 , A61P17/06 , A61P19/02 , A61P19/10 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/18 , A61P35/00 , A61P37/02 , A61P37/06 , A61P43/00 , C07D333/36 , C07D333/38 , C07D333/40
CPC分类号： C07D333/38
摘要： The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.
摘要翻译：本发明提供了使用它们用IkappaB的IKK-β磷酸化的氨基噻吩抑制剂治疗疾病的新型化合物和方法。在这样做时，这些氨基噻吩抑制剂阻断转录因子NF-κB的病理活化，其中涉及NF-κB的过度活化。

7. 发明申请

US20230050068A1 DISPLAYING A PROFILE FROM A CONTENT FEED WITHIN A MESSAGING SYSTEM 有权
公开(公告)号：US20230050068A1
公开(公告)日：2023-02-16
申请号：US17820171
申请日：2022-08-16
申请人： Newar Husam Al Majid , Alex Beltyukov , Nathan Kenneth Boyd , Jacob Catalano , Wenbin Chen , Matthew Lee Cook , Andrew Grosvenor Cooper , Zuoyou Gu , Yue Hu , Timothy Kautz , Edward Koai , Karen Jong-Hwi Lee , Chinmay Lonkar , Lu Lu , Zachary Lupei , Charles Melbye , Celia Nicole Mourkogiannis , Chiung-Fu Shih , Brian Yee , Jiawen Zeng , Dongguang Zhao
发明人： Newar Husam Al Majid , Alex Beltyukov , Nathan Kenneth Boyd , Jacob Catalano , Wenbin Chen , Matthew Lee Cook , Andrew Grosvenor Cooper , Zuoyou Gu , Yue Hu , Timothy Kautz , Edward Koai , Karen Jong-Hwi Lee , Chinmay Lonkar , Lu Lu , Zachary Lupei , Charles Melbye , Celia Nicole Mourkogiannis , Chiung-Fu Shih , Brian Yee , Jiawen Zeng , Dongguang Zhao
IPC分类号： G06F16/435 , G06F16/44 , G06F3/0488
摘要： Aspects of the present disclosure involve a system comprising a computer-readable storage medium storing a program and method for displaying a profile from a content feed within a messaging system. The program and method provide for receiving by a messaging application, first user input corresponding to a request for a content feed, the content feed comprising a plurality of media content items; providing, in response to receiving the first user input, for display of the content feed; receiving, by the messaging application, second user input of a predefined gesture performed with respect to a first media content item of the plurality of media content items; determining, in response to receiving the second user input and based on the first media content item, to display a public profile associated with the first media content item; and providing, based on the determining, for display of the public profile.

8. 发明授权

US08643528B1 Analog-to-digital converter 有权
标题翻译：模数转换器
公开(公告)号：US08643528B1
公开(公告)日：2014-02-04
申请号：US13565399
申请日：2012-08-02
申请人： Yue Hu , Ajay Kumar
发明人： Yue Hu , Ajay Kumar
IPC分类号： H03M1/12 , H03M3/02
CPC分类号： H03M3/424 , H03M3/47
摘要： An analog-to-digital converter (ADC) comprises a plurality of time-interleaved integrating ADCs having feedback from an integrated output signal. In variations, the time-interleaved integrating ADCs have feedback compensation from at least one measure of quantization error. The time-interleaved integrating ADCs may also share a single comparator and may also share a single current source.
摘要翻译：模数转换器（ADC）包括具有来自积分输出信号的反馈的多个时间交错积分ADC。在变化中，时间交织的积分ADC具有来自量化误差的至少一个量度的反馈补偿。时间交织的积分ADC还可以共享单个比较器，并且还可以共享单个电流源。

9. 发明申请

US20100267397A1 METHOD AND APPARATUS FOR DETERMINING A MOBILITY OF A MOBILE STATION IN A WIRELESS COMMUNICATION SYSTEM 有权
标题翻译：用于确定无线通信系统中移动站的移动性的方法和装置
公开(公告)号：US20100267397A1
公开(公告)日：2010-10-21
申请号：US12435806
申请日：2009-05-05
申请人： Xiaohui Shen , Sheng-Yue Hu , Hong-Lei Liu , Yinyan Wang
发明人： Xiaohui Shen , Sheng-Yue Hu , Hong-Lei Liu , Yinyan Wang
IPC分类号： H04W64/00
CPC分类号： H04W64/006
摘要： An infrastructure-based mobililty determination module (MDM) receives multiple measurement reports from the MS and, for each received measurement report, stores values corresponding to values included in the report that are associated with measurements of parameters associated with received signals, wherein each stored value is stored in association with a wireless access node sourcing the corresponding signal. For each of one or more pairings of received measurement reports, the MDM then determines a signal parameter measurement change value corresponding to a change from the signal parameter measurement values associated with a first measurement report of the pairing to the signal parameter measurement values associated with a second measurement report of the pairing. Based on the one or more signal parameter measurement change values, the MDM determines an average signal parameter measurement change value and, based on the average signal parameter measurement change value, determines a mobility of the MS.
摘要翻译：基于基础设施的移动确定模块（MDM）从MS接收多个测量报告，并且对于每个接收到的测量报告，存储对应于报告中包括的值与与接收信号相关联的参数的测量相关联的值，其中每个存储值与提供相应信号的无线接入节点相关联地存储。对于所接收的测量报告的一个或多个配对中的每一个，MDM然后确定对应于从与配对的第一测量报告相关联的信号参数测量值到与相关联的测量报告相关联的信号参数测量值的变化的信号参数测量改变值配对的第二个测量报告。基于一个或多个信号参数测量改变值，MDM确定平均信号参数测量改变值，并且基于平均信号参数测量改变值来确定MS的移动性。

10. 发明授权

US07375131B2 NF-κB inhibitors 失效
标题翻译： NF-κB抑制剂
公开(公告)号：US07375131B2
公开(公告)日：2008-05-20
申请号：US10516836
申请日：2003-05-29
申请人： James F. Callahan , Yue Hu Li
发明人： James F. Callahan , Yue Hu Li
IPC分类号： A61K31/38 , C07D333/36
CPC分类号： C07D333/38
摘要： The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.
摘要翻译：本发明提供了使用它们用IkappaB的IKK-β磷酸化的氨基噻吩抑制剂治疗疾病的新型化合物和方法。在这样做时，这些氨基噻吩抑制剂阻断转录因子NF-κB的病理活化，其中涉及NF-κB的过度活化。

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