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1. 发明授权

US08388670B1 Sensor/lead systems for use with implantable medical devices 有权
标题翻译：用于可植入医疗器械的传感器/引线系统
公开(公告)号：US08388670B1
公开(公告)日：2013-03-05
申请号：US11623663
申请日：2007-01-16
申请人： Yongning Zou , James B. Hamilton , Alan B. Vogel , Chris Sorensen , Ryan Albu
发明人： Yongning Zou , James B. Hamilton , Alan B. Vogel , Chris Sorensen , Ryan Albu
IPC分类号： A61F7/00
CPC分类号： A61B5/6869 , A61B5/01 , A61B5/029 , A61B5/14532 , A61B5/14539 , A61B5/14542 , A61B5/7285 , A61B2562/0204 , A61B2562/0219 , A61B2562/0247 , A61N1/056 , A61N1/368 , A61N1/3704 , A61N1/3962
摘要： Techniques are provided for equipping sensing/pacing leads with physiological sensors without requiring additional conductors within the leads. In a bipolar lead example for use with a pacemaker, a sensor is connected between tip and ring conductors of the lead. The sensor is configured to be activated only in response to enhanced pacing pulse (EPPs) having magnitudes or durations greater than typical pacing pulses or in response to impedance detection pulses (IMPs). In a unipolar example, the sensor is connected to the tip conductor and includes an output terminal on the external housing of the lead for providing a return current path to the pacemaker. The sensor of the unipolar lead is likewise configured to respond only to EPPs or IMPs. In other examples, the sensors are configured to be fitted to the external housing of the lead and to derive power from the lead via electromagnetic induction. Still other examples include actuators rather than sensors.
摘要翻译：提供了技术，用于使传感/起搏线与生理传感器配套，而不需要引线内的额外导线。在与起搏器一起使用的双极引线示例中，传感器连接在引线的尖端和环形导体之间。传感器被配置为仅响应于具有大于典型起搏脉冲的大小或持续时间或响应于阻抗检测脉冲（IMPs）的增强的起搏脉冲（EPP）被激活。在单极示例中，传感器连接到尖端导体，并且在引线的外部壳体上包括输出端子，用于提供到起搏器的返回电流路径。单极引线的传感器同样配置为只响应EPP或IMP。在其他示例中，传感器被配置为安装到引线的外部壳体并且通过电磁感应从引线导出功率。还有其他示例包括致动器而不是传感器。

2. 发明授权

US07752002B2 Methods and apparatus for non-invasive implantable pressure sensor calibration 失效
标题翻译：非侵入性植入式压力传感器校准方法和装置
公开(公告)号：US07752002B2
公开(公告)日：2010-07-06
申请号：US12130789
申请日：2008-05-30
申请人： Yang Zhang , Yongning Zou , Dan E. Gutfinger
发明人： Yang Zhang , Yongning Zou , Dan E. Gutfinger
IPC分类号： G01L27/00 , A61B5/08
CPC分类号： A61B5/02156 , A61B5/02158 , A61B5/036 , A61B5/097 , A61B2560/0223 , G01L27/005
摘要： An economical, repeatable, and non-invasive method and apparatus for the calibration of implantable pressure sensors that can minimize patient discomfort and risk of infection. In one embodiment, a calibration system for calibrating a first pressure sensor coupled to a management device and implanted into a human patient is provided. The calibration system includes a mouthpiece, a pump, a second pressure sensor, and a computer. The pump provides a positive pressure into an airway of the human patient via the mouthpiece. The second pressure sensor measures the airway pressure of the human patient, and the computer is coupled to the pump and monitors pressures measured by the first and second pressure sensors. Here, the computer also calculates one or more calibration constants based on the pressures measured by the first and second pressure sensors and provides the calibration constants to the management device to calibrate the first pressure sensor.
摘要翻译：用于校准植入式压力传感器的经济，可重复和非侵入性的方法和装置，其可以最小化患者的不适和感染的风险。在一个实施例中，提供了用于校准耦合到管理装置并植入人类患者的第一压力传感器的校准系统。校准系统包括接口管，泵，第二压力传感器和计算机。泵通过接口口向人类患者的气道提供正压力。第二压力传感器测量人类患者的气道压力，并且计算机耦合到泵并监测由第一和第二压力传感器测量的压力。这里，计算机还基于由第一和第二压力传感器测量的压力计算一个或多个校准常数，并将校准常数提供给管理装置以校准第一压力传感器。

3. 发明申请

US20090299672A1 METHODS AND APPARATUS FOR NON-INVASIVE IMPLANTABLE PRESSURE SENSOR CALIBRATION 失效
标题翻译：非侵入式压力传感器校准的方法和装置
公开(公告)号：US20090299672A1
公开(公告)日：2009-12-03
申请号：US12130789
申请日：2008-05-30
申请人： Yang Zhang , Yongning Zou , Dan E. Gutfinger
发明人： Yang Zhang , Yongning Zou , Dan E. Gutfinger
IPC分类号： G01L27/00
CPC分类号： A61B5/02156 , A61B5/02158 , A61B5/036 , A61B5/097 , A61B2560/0223 , G01L27/005
摘要： An economical, repeatable, and non-invasive method and apparatus for the calibration of implantable pressure sensors that can minimize patient discomfort and risk of infection. In one embodiment, a calibration system for calibrating a first pressure sensor coupled to a management device and implanted into a human patient is provided. The calibration system includes a mouthpiece, a pump, a second pressure sensor, and a computer. The pump provides a positive pressure into an airway of the human patient via the mouthpiece. The second pressure sensor measures the airway pressure of the human patient, and the computer is coupled to the pump and monitors pressures measured by the first and second pressure sensors. Here, the computer also calculates one or more calibration constants based on the pressures measured by the first and second pressure sensors and provides the calibration constants to the management device to calibrate the first pressure sensor.
摘要翻译：用于校准植入式压力传感器的经济，可重复和非侵入性的方法和装置，其可以最小化患者的不适和感染的风险。在一个实施例中，提供了用于校准耦合到管理装置并植入人类患者的第一压力传感器的校准系统。校准系统包括接口管，泵，第二压力传感器和计算机。泵通过接口口向人类患者的气道提供正压力。第二压力传感器测量人类患者的气道压力，并且计算机耦合到泵并监测由第一和第二压力传感器测量的压力。这里，计算机还基于由第一和第二压力传感器测量的压力计算一个或多个校准常数，并将校准常数提供给管理装置以校准第一压力传感器。

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