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1. 发明专利

IL278473D0 Methods of prognosing, determining treatment course and treating multiple myeloma 未知
公开(公告)号：IL278473D0
公开(公告)日：2022-06-01
申请号：IL27847320
申请日：2020-11-03
申请人： YEDA RES & DEV , ICHILOV TECH LTD , YAEL COHEN , IDO AMIT , CHAMUTAL BORNSTEIN OVITS , ASSAF WEINER , MOR ZADA , SHUANG YIN WANG
发明人： YAEL COHEN , IDO AMIT , CHAMUTAL BORNSTEIN-OVITS , ASSAF WEINER , MOR ZADA , SHUANG-YIN WANG
IPC分类号： A61K31/49 , A61K31/52 , A61K31/573 , A61K31/69 , A61K39/395 , A61P35/00 , G01N33/48 , G01N33/50
摘要： A method of prognosing a subject diagnosed with multiple myeloma (MM)is provided. Also provided a method of treating a subject diagnosed with MM selected expressing intracellular PPIA and/or RRM2 above a predetermined threshold, the method comprising administering to the subject a therapeutically effective amount of at least one agent which specifically down-regulates activity or expression of PPIA and/or RRM2, thereby treating the subject.

2. 发明专利

IL278473A Methods of prognosing, determining treatment course and treating multiple myeloma 未知
公开(公告)号：IL278473A
公开(公告)日：2022-06-01
申请号：IL27847320
申请日：2020-11-03
申请人： YEDA RES & DEV , ICHILOV TECH LTD , YAEL COHEN , IDO AMIT , CHAMUTAL BORNSTEIN OVITS , ASSAF WEINER , MOR ZADA , SHUANG YIN WANG
发明人： YAEL COHEN , IDO AMIT , CHAMUTAL BORNSTEIN-OVITS , ASSAF WEINER , MOR ZADA , SHUANG-YIN WANG
摘要： A method of prognosing a subject diagnosed with multiple myeloma (MM)is provided. Also provided a method of treating a subject diagnosed with MM selected expressing intracellular PPIA and/or RRM2 above a predetermined threshold, the method comprising administering to the subject a therapeutically effective amount of at least one agent which specifically down-regulates activity or expression of PPIA and/or RRM2, thereby treating the subject.

3. 发明专利

FR2751885B1 未知
公开(公告)号：FR2751885B1
公开(公告)日：1998-10-23
申请号：FR9609673
申请日：1996-07-31
申请人： HSIEH YIN WANG
发明人： HSIEH YIN WANG
IPC分类号： A63C17/00 , A63C17/06 , A63C17/14

4. 发明专利

DE29613117U1 未知
公开(公告)号：DE29613117U1
公开(公告)日：1996-12-05
申请号：DE29613117
申请日：1996-07-31
申请人： HSIEH YIN WANG , LIN WANG JUNG
IPC分类号： A63C17/06 , A63C17/26

5. 发明专利

GB2315680B Improved skate 未知
公开(公告)号：GB2315680B
公开(公告)日：1998-07-22
申请号：GB9616104
申请日：1996-07-31
申请人： HSIEH YIN WANG , LIN WANG JUNG
发明人： HSIEH YIN-WANG
IPC分类号： A63C17/06 , A63C17/26

6. 发明专利

GB9616104D0 Improved skate 未知
公开(公告)号：GB9616104D0
公开(公告)日：1996-09-11
申请号：GB9616104
申请日：1996-07-31
申请人： HSIEH YIN WANG , LIN WANG JUNG
IPC分类号： A63C17/06 , A63C17/26

7. 发明专利

GB2315680A Spring assisted skates 未知
公开(公告)号：GB2315680A
公开(公告)日：1998-02-11
申请号：GB9616104
申请日：1996-07-31
申请人： HSIEH YIN WANG , LIN WANG JUNG
发明人： HSIEH YIN-WANG
IPC分类号： A63C17/06 , A63C17/26
摘要： A skate comprises a main body 10 having front and rear sockets 16,17 locating compression springs 91,92 therein. Wheels 40,50 are mounted on supports 20,30 which are pivoted on the main body by pivots 25,35. The compression springs are held in place by discs 93,94 and connecting members 95,96 which are themselves pivotably mounted on the supports 20,30. Also present are two torsion springs 60,70 which abut the shafts 26,36 on the connecting members and the base of the main body and which reinforce the action of the compression spring. The skate may have a brake and the rollers can be one-way.

8. 发明专利

FR2751885A1 Sprung roller mechanism for roller skate 未知
公开(公告)号：FR2751885A1
公开(公告)日：1998-02-06
申请号：FR9609673
申请日：1996-07-31
申请人： HSIEH YIN WANG
发明人： HSIEH YIN WANG
IPC分类号： A63C17/00 , A63C17/06 , A63C17/14
摘要： The roller mechanism has a main body (10) with front and rear bearing surfaces. They are positioned above respective reception spaces for compression springs, coupled to front and rear rollers (40,50) via elastic elements. The rollers are enclosed by respective housings (20,30). Each housing is secured to the main body at the centre of the latter via a pair of clamp plates and a cooperating pivot pin.

9. 发明授权

US08947663B2 Dual-modulation faraday rotation spectroscopy 有权
标题翻译：双调制法拉第旋转光谱
公开(公告)号：US08947663B2
公开(公告)日：2015-02-03
申请号：US14215739
申请日：2014-03-17
申请人： Yin Wang , Gerard Wysocki
发明人： Yin Wang , Gerard Wysocki
IPC分类号： G01J4/00 , G01J4/04 , G01N21/21
CPC分类号： G01N21/21 , G01J3/447 , G01N21/1717 , G01N2021/1727
摘要： A dual-modulation Faraday rotation spectroscopic (FRS) system is disclosed. The FRS system uses an FRS sample cell configured to subject a sample to a low frequency modulated magnetic field. The system includes a polarized laser light source configured to generate a high frequency wavelength-modulated light beam incident on the sample, the high frequency wavelength-modulated light beam being modulated at a higher frequency than the low frequency modulated magnetic field. A polarizer is configured to receive from the sample a transmitted light beam having a modulated polarization having a polarization rotation and translate the modulated polarization of the transmitted light beam into an intensity modulated beam. A photodetector is configured to detect the intensity modulated beam and generate a photodetector signal. A dual demodulator is coupled to the photodetector and is configured to demodulate the photodetector signal.
摘要翻译：公开了一种双调制法拉第旋转光谱（FRS）系统。 FRS系统使用被配置为使样本进入低频调制磁场的FRS采样单元。该系统包括被配置为产生入射在样品上的高频波长调制光束的偏振激光光源，高频波长调制光束以比低频调制磁场更高的频率进行调制。偏振器被配置为从样本接收具有具有偏振旋转的调制偏振的透射光束，并将透射光束的调制偏振转换成强度调制光束。光电检测器被配置为检测强度调制光束并产生光电检测器信号。双重解调器耦合到光电检测器并且被配置为解调光电检测器信号。

10. 发明申请

US20140268148A1 Dual-Modulation Faraday Rotation Spectroscopy 有权
标题翻译：双调制法拉第旋转光谱
公开(公告)号：US20140268148A1
公开(公告)日：2014-09-18
申请号：US14215739
申请日：2014-03-17
申请人： Yin Wang , Gerard Wysocki
发明人： Yin Wang , Gerard Wysocki
IPC分类号： G01J4/04 , G01N21/21
CPC分类号： G01N21/21 , G01J3/447 , G01N21/1717 , G01N2021/1727
摘要： A dual-modulation Faraday rotation spectroscopic (FRS) system is disclosed. The FRS system uses an FRS sample cell configured to subject a sample to a low frequency modulated magnetic field. The system includes a polarized laser light source configured to generate a high frequency wavelength-modulated light beam incident on the sample, the high frequency wavelength-modulated light beam being modulated at a higher frequency than the low frequency modulated magnetic field. A polarizer is configured to receive from the sample a transmitted light beam having a modulated polarization having a polarization rotation and translate the modulated polarization of the transmitted light beam into an intensity modulated beam. A photodetector is configured to detect the intensity modulated beam and generate a photodetector signal. A dual demodulator is coupled to the photodetector and is configured to demodulate the photodetector signal.
摘要翻译：公开了一种双调制法拉第旋转光谱（FRS）系统。 FRS系统使用被配置为使样本进入低频调制磁场的FRS采样单元。该系统包括被配置为产生入射在样品上的高频波长调制光束的偏振激光光源，高频波长调制光束以比低频调制磁场更高的频率进行调制。偏振器被配置为从样本接收具有具有偏振旋转的调制偏振的透射光束，并将透射光束的调制偏振转换成强度调制光束。光电检测器被配置为检测强度调制光束并产生光电检测器信号。双重解调器耦合到光电检测器并且被配置为解调光电检测器信号。

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