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1. 发明授权

US08663967B2 Arginine deiminase mutant and preparation and application thereof 有权
标题翻译：精氨酸脱亚氨酶突变体及其制备及应用
公开(公告)号：US08663967B2
公开(公告)日：2014-03-04
申请号：US13214398
申请日：2011-08-22
申请人： Yanshan Huang , Jiwan Qiu , Xiaoyu Fu , Min Fan , Yujiao Wang , Yefei Wang
发明人： Yanshan Huang , Jiwan Qiu , Xiaoyu Fu , Min Fan , Yujiao Wang , Yefei Wang
IPC分类号： C12N11/02 , C12N11/08 , C12N9/00 , C12N9/78 , C12N1/20 , C12N15/00 , C07H21/04
CPC分类号： C12N9/78 , A61K38/00 , C12Y305/03006
摘要： The present invention relates to an arginine deiminase mutant with partial lysine-deficient and preparation and application thereof. The arginine deiminase mutant of the present invention has enzymatic activity of degrading arginine into citruline; compared with the arginine deiminase with the amino acid sequence of SEQ ID NO: 1, the amino acid sequence comprises one or more of K9N, T, K59Q, K66R, A, K93E, A, Q, K111R, A, K119Q, L, M, K121Q, I, K122E, L, K126E, S, R, K178I, E, D, K196I, R, K209G, T, D, K243E, V, R, K249D, Q, K263N, Q, K279Y, T, K293R, H, E, K325V, I, K380T, R, E, and K406E, D, S substitutions. Compared with PEG modified natural derived arginine deiminase, the PEG modified arginine deiminase mutant of the present invention retain better bioactivity; and because the quantity of lysine in arginine deiminase is reduced, the PEG modified products are more uniform and can be applied to clinical treatment of hepatoma, melanoma and the like.
摘要翻译：本发明涉及具有部分赖氨酸缺陷型及其制备及应用的精氨酸脱亚胺酶突变体。本发明的精氨酸脱亚胺酶突变体具有将精氨酸降解成柠檬酸的酶活性; 与具有SEQ ID NO：1的氨基酸序列的精氨酸脱亚氨酶相比，氨基酸序列包含K9N，T，K59Q，K66R，A，K93E，A，Q，K111R，A，K119Q，L， M，K121Q，I，K122E，L，K126E，S，R，K178I，E，D，K196I，R，K209G，T，D，K243E，V，R，K249D，Q，K263N，Q，K279Y， K293R，H，E，K325V，I，K380T，R，E和K406E，D，S取代。与PEG改性天然衍生的精氨酸脱亚胺酶相比，本发明的PEG修饰的精氨酸脱亚氨酶突变体保持较好的生物活性; 并且由于精氨酸去酰亚胺酶中赖氨酸的量减少，PEG改性产物更均匀，可用于肝癌，黑素瘤等的临床治疗。

2. 发明授权

US07845803B2 Projector apparatus 有权
标题翻译：投影仪
公开(公告)号：US07845803B2
公开(公告)日：2010-12-07
申请号：US11850322
申请日：2007-09-05
申请人： Qiang Lv , Xianglin Zhang , Toshihiro Saruwatari , Yanshan Huang , Tadashi Renbutsu , Shoji Okazaki , Xiangfei Kong , Wentian Tang
发明人： Qiang Lv , Xianglin Zhang , Toshihiro Saruwatari , Yanshan Huang , Tadashi Renbutsu , Shoji Okazaki , Xiangfei Kong , Wentian Tang
IPC分类号： G03B21/16
CPC分类号： G03B21/16 , G03B21/145 , G03B21/22 , H04N9/3105 , H04N9/3144
摘要： The invention enables efficient cooling of: a light source providing source light; an optical system adapted to split the source light received from the light source into three primary colors R, G, and B; and a power supply unit for supplying electric power to various electric components installed in a casing of a projector apparatus. To do so, a first fan is arranged between the light source and the power supply unit such that its air inspiration face is directed to the power supply unit and its air expiration face is directed to the light source. Further, a second fan, adapted to inspire air from within the projector apparatus, is provided in the central area of the projector apparatus. On the air expiration side of the second fan is a cooling duct for cooling the light source and optical system. In addition, a third fan for cooling a G-LCP unit and an R-LCP unit of the image synthesizing device and a fourth fan for cooling a B-LCP and an R-LCP unit of the image synthesizing device are provided in such a way that the streams of air expired from said third and fourth fans intersect each other. The invention allows operation of a projector apparatus with a fewer fans, yet achieves suppression of exhaust air temperature and noise, and cost reduction as well.
摘要翻译：本发明能够有效地冷却：提供源光的光源; 适于将从光源接收的源光分成三原色R，G和B的光学系统; 以及用于向安装在投影仪装置的壳体中的各种电气部件供电的电源单元。为此，第一风扇布置在光源和电源单元之间，使得其空气吸入面被引导到电源单元，并且其空气呼出面指向光源。此外，在投影仪装置的中央区域设置有适于在投影仪装置内启发空气的第二风扇。在第二风扇的空气呼出侧是用于冷却光源和光学系统的冷却管道。此外，用于冷却图像合成装置的G-LCP单元和R-LCP单元的第三风扇和用于冷却图像合成装置的B-LCP和R-LCP单元的第四风扇设置在从所述第三和第四风扇流过的空气流彼此相交的方式。本发明允许具有较少风扇的投影仪设备的操作，而且还实现排气温度和噪声的抑制以及降低成本。

3. 发明申请

US20080252858A1 PROJECTOR 审中-公开
标题翻译：投影机
公开(公告)号：US20080252858A1
公开(公告)日：2008-10-16
申请号：US12062892
申请日：2008-04-04
申请人： Wanjun ZHENG , Yanyun YAN , Xiangdong LIANG , Xiangfei KONG , Yun WANG , Xiaolin MAO , Yi GUAN , Yanshan HUANG , Toshihiro SARUWATARI , Shoji OKAZAKI , Tadashi RENBUTSU
发明人： Wanjun ZHENG , Yanyun YAN , Xiangdong LIANG , Xiangfei KONG , Yun WANG , Xiaolin MAO , Yi GUAN , Yanshan HUANG , Toshihiro SARUWATARI , Shoji OKAZAKI , Tadashi RENBUTSU
IPC分类号： G03B21/16
CPC分类号： G03B21/16
摘要： A projector (1) has: a LAN card (800) having thereon an IC; liquid crystal panels (34) for modulating red, green, and blue light; optical components that includes polarization beam splitter (PBS) (23); and fans for cooling the optical components. The projector is provided with cooling ducts, which include a first air duct (411) having one end connected to the fan (41) and another end connected to an outlet for sending air to the liquid crystal panel for red light, a second air duct (421) having one end connected to the fan (42) and another end connected to an outlet for sending air to the liquid crystal panel for green light, and a third air duct (431) having one end connected to the fan (43) and another end connected to an outlet for sending air to the liquid crystal panel for blue light. The cooling ducts also include a branching air duct (412 or 422) that extends to the IC on the LAN card.
摘要翻译：投影仪（1）具有：具有IC的LAN卡（800）; 用于调制红色，绿色和蓝色光的液晶面板（34）包括偏振分束器（PBS）（23）的光学部件; 和风扇用于冷却光学元件。投影仪设置有冷却管道，该冷却管道包括一端连接到风扇（41）的第一风道（411），另一端连接到用于将空气送至用于红灯的液晶面板的出口，第二风道（421），其一端连接到所述风扇（42），另一端连接到用于将空气送到用于绿色光的液晶面板的出口;以及第三风道（431），其一端连接到所述风扇（43）另一端连接到用于向蓝色光的液晶面板发送空气的出口。冷却管道还包括延伸到LAN卡上的IC的分支空气管道（412或422）。

4. 发明申请

US20080246929A1 PROJECTION TYPE IMAGE DISPLAY APPARATUS 有权
标题翻译：投影类型图像显示设备
公开(公告)号：US20080246929A1
公开(公告)日：2008-10-09
申请号：US12098086
申请日：2008-04-04
申请人： Xiaolin MAO , Yanyun YAN , Xiangdong LIANG , Xiangfei KONG , Yun WANG , Wanjun ZHENG , Yi GUAN , Yanshan HUANG , Toshihiro SARUWATARI , Shoji OKAZAKI , Tadashi RENBUTSU
发明人： Xiaolin MAO , Yanyun YAN , Xiangdong LIANG , Xiangfei KONG , Yun WANG , Wanjun ZHENG , Yi GUAN , Yanshan HUANG , Toshihiro SARUWATARI , Shoji OKAZAKI , Tadashi RENBUTSU
IPC分类号： G03B21/14
CPC分类号： G03B21/16 , G03B21/145 , G03B21/22
摘要： In a projection type image display apparatus, a noise removal filter portion 15 is separated from a power source unit body 14. The separated noise removal filter portion 15 is provided in the vicinity of a side wall of a housing on which a power source inlet is provided, and of the power source unit body 14, respectively. Specifically, the power source unit body 14 is provided along a side wall of a front face of the horizontally-long housing of the projection type image display apparatus and the noise removal filter portion 15 is provided in a position opposed to the power source unit body 14 in a side wall of the back face. As a result, even when a light source lamp has a higher output, the projection type image display apparatus can achieve reduced noise by an improved cooling capability and reduced cost enabled by an efficient Electro Magnetic Compatibility (EMC) measure and the like.
摘要翻译：在投影型图像显示装置中，噪声去除滤波器部分15与电源单元主体14分离。分离的噪声去除滤波器部分15分别设置在设置有电源入口的壳体的侧壁附近和电源单元体14的附近。具体地，电源单元体14沿着投影型图像显示装置的水平方向的壳体的正面的侧壁设置，并且噪声去除滤波器部15设置在与电源单元体相对的位置 14在背面的侧壁中。结果，即使当光源灯具有更高的输出时，投影型图像显示装置也可以通过改善的冷却能力降低噪音并且通过有效的电磁兼容性（EMC）测量等降低成本。

5. 发明授权

US08511832B2 Projection type image display apparatus with angled exhaust fan 有权
标题翻译：具有倾斜排风扇的投影型图像显示装置
公开(公告)号：US08511832B2
公开(公告)日：2013-08-20
申请号：US12098103
申请日：2008-04-04
申请人： Wanjun Zheng , Yanyun Yan , Xiangdong Liang , Xiangfei Kong , Yun Wang , Xiaoling Mao , Yi Guan , Yanshan Huang , Toshihiro Saruwatari , Shoji Okazaki , Tadashi Renbutsu
发明人： Wanjun Zheng , Yanyun Yan , Xiangdong Liang , Xiangfei Kong , Yun Wang , Xiaoling Mao , Yi Guan , Yanshan Huang , Toshihiro Saruwatari , Shoji Okazaki , Tadashi Renbutsu
IPC分类号： G03B21/18
CPC分类号： G03B21/16
摘要： A projector which includes a first exhaust fan discharging exhaust air from a light source lamp to exterior and a second exhaust fan discharging exhaust air from parts other than the light source lamp are arranged to be adjacent to each other. An end of the exhaust fan facing the other exhaust fan is moved to the inner side and the one exhaust fan is inclined to discharge air in an exhaust direction toward a direction along which air is discharged from the other exhaust fan. There is provided a cooling fan that blows air to an interior air blow outlet communicating with the interior of the light source lamp and exterior air blow outlets communicating with an outer surface to cool the light source lamp. The exterior air blow outlets are deviated from the center of the outer surface of the light source lamp.
摘要翻译：包括将排出空气从光源灯排出到外部的第一排气扇和从除了光源灯以外的部分排出废气的第二排风扇的投影仪被布置成彼此相邻。面向另一个排气风扇的排风扇的一端向内侧移动，一个排气风扇倾斜，从排气方向向空气排出的方向排出另一排风扇。提供了一种冷却风扇，其将空气吹送到与光源灯的内部连通的内部空气吹出口和与外表面连通的外部吹风口，以冷却光源灯。外部空气吹出口偏离光源灯的外表面的中心。

6. 发明授权

US08107021B2 Liquid crystal projection apparatus utilizing image synthesizing unit with liquid crystal panel holders 有权
标题翻译：利用具有液晶面板支架的图像合成单元的液晶投影装置
公开(公告)号：US08107021B2
公开(公告)日：2012-01-31
申请号：US12368484
申请日：2009-02-10
申请人： Xianglin Zhang , Jieyang Wu , Tadashi Renbutsu , Shoji Okazaki , Yanshan Huang
发明人： Xianglin Zhang , Jieyang Wu , Tadashi Renbutsu , Shoji Okazaki , Yanshan Huang
IPC分类号： G02F1/1335 , G03B21/26 , G03B21/00
CPC分类号： G02B7/1805 , H04N9/3105 , H04N9/315
摘要： A liquid crystal projection apparatus having an image synthesizing unit including a color synthesization prism having an upper surface, a lower surface facing the upper surface, and three light incident faces between the upper and lower surfaces; an upper prism pedestal provided on the upper surface of the color synthesization prism; a lower prism pedestal provided on the lower surface of the color synthesization prism; an upper liquid crystal panel holder provided on the upper prism pedestal and having first jointing sections, a lower liquid crystal panel holder provided on the lower prism pedestal and having second jointing sections; three liquid crystal panels; and three liquid crystal panel mounting members securely fixing thereon the three liquid crystal panels, the three mounting members arranged on the respective three incident faces of the color synthesization prism joining the first jointing sections located in association with the respective incident faces to corresponding second jointing sections located in association with the corresponding incident faces.
摘要翻译：一种具有图像合成单元的液晶投影设备，该图像合成单元包括具有上表面，与上表面相对的下表面和上表面和下表面之间的三个光入射面的彩色合成棱镜; 设置在彩色合成棱镜的上表面上的上棱镜基座; 设置在彩色合成棱镜的下表面上的下棱镜基座; 设置在上棱镜基座上并具有第一接合部的上液晶面板保持件，设置在下棱镜基座上的下液晶面板保持架，具有第二接合部; 三个液晶面板; 以及三个液晶面板安装构件，其牢固地固定在三个液晶面板上，三个安装构件被配置在将与各个入射面相关联的第一接合部分接合的彩色合成棱镜的相应的三个入射面上，与相应的事件面相关联。

7. 发明授权

US08104902B2 Projection image display apparatus having a noise removal filter portion 有权
标题翻译：具有噪声去除滤波器部分的投影图像显示装置
公开(公告)号：US08104902B2
公开(公告)日：2012-01-31
申请号：US12098086
申请日：2008-04-04
申请人： Xiaolin Mao , Yanyun Yan , Xiangdong Liang , Xiangfei Kong , Yun Wang , Wanjun Zheng , Yi Guan , Yanshan Huang , Toshihiro Saruwatari , Shoji Okazaki , Tadashi Renbutsu
发明人： Xiaolin Mao , Yanyun Yan , Xiangdong Liang , Xiangfei Kong , Yun Wang , Wanjun Zheng , Yi Guan , Yanshan Huang , Toshihiro Saruwatari , Shoji Okazaki , Tadashi Renbutsu
IPC分类号： G03B21/14 , G03B21/22 , H04N5/217
CPC分类号： G03B21/16 , G03B21/145 , G03B21/22
摘要： In a projection image display apparatus, a noise removal filter portion 15 is separated from a power source unit body 14. The separated noise removal filter portion 15 is provided in the vicinity of a side wall of a housing on which a power source inlet is provided, and of the power source unit body 14, respectively. Specifically, the power source unit body 14 is provided along a side wall of a front face of the horizontally-long housing of the projection image display apparatus and the noise removal filter portion 15 is provided in a position opposed to the power source unit body 14 in a side wall of the back face. As a result, even when a light source lamp has a higher output, the projection image display apparatus can achieve reduced noise by an improved cooling capability and reduced cost enabled by an efficient Electro Magnetic Compatibility (EMC) measure and the like.
摘要翻译：在投影图像显示装置中，噪声去除滤波器部分15与电源单元主体14分离。分离的噪声去除滤波器部分15设置在壳体的设置有电源入口的侧壁附近，以及电源单元主体14。具体而言，电源单元主体14沿着投影图像显示装置的水平方向的壳体的正面的侧壁设置，并且噪声去除滤波器部15设置在与电源单元主体14相对的位置在背面的侧壁。结果，即使当光源灯具有较高的输出时，投影图像显示装置也可以通过改善的冷却能力降低噪音并且通过有效的电磁兼容性（EMC）措施等降低成本。

8. 发明授权

US07943898B2 Projector apparatus including a lower holder having lens and lamp fixing slots 有权
标题翻译：投影仪装置包括具有透镜和灯固定槽的下支架
公开(公告)号：US07943898B2
公开(公告)日：2011-05-17
申请号：US11850320
申请日：2007-09-05
申请人： Xiangfen Kong , Xianglin Zhang , Shoji Okazaki , Yanshan Huang , Tadashi Renbutsu , Toshihiro Saruwatari , Wentian Tang , Qiang Lv
发明人： Xiangfen Kong , Xianglin Zhang , Shoji Okazaki , Yanshan Huang , Tadashi Renbutsu , Toshihiro Saruwatari , Wentian Tang , Qiang Lv
IPC分类号： H01J5/02
CPC分类号： G03B21/20 , G03B21/145
摘要： A projector apparatus and a lamp fixation structure for use with the projector apparatus are disclosed. The lamp fixation structure has a lower holder, which includes an integrally formed lower holder lens section and a lower holder lamp section. The lower holder lens section defines a lens fitting slot for fixing a lens, and a lower holder lamp section defines a lamp fitting slot for fixing a lamp. The lens fixing slot includes an upper holder connected to the lower holder. The lamp fixation structure also includes an integrally formed metal holder, which has an elastic top plate, elastic lateral plates, a front plate, an elastic bottom plate, and elastic jointing plates. The inventive lamp fixation structure of the projector apparatus consists of a fewer components and can be assembled in a simple manner, yet it is highly wrought.
摘要翻译：公开了一种与投影仪装置一起使用的投影仪装置和灯固定结构。灯具固定结构具有下保持器，其包括整体形成的下保持器透镜部分和下保持器灯部分。下支架透镜部限定用于固定透镜的透镜配合槽，下保持器灯部限定用于固定灯的灯配合槽。透镜固定槽包括连接到下支架的上支架。灯固定结构还包括具有弹性顶板，弹性侧板，前板，弹性底板和弹性接合板的整体形成的金属保持器。投影仪设备的本发明的灯固定结构由较少的组件组成，并且可以以简单的方式组装，但是它是高度锻造的。

9. 发明申请

US20090231498A1 LIQUID CRYSTAL PROJECTION APPARATUS 有权
标题翻译：液晶投影设备
公开(公告)号：US20090231498A1
公开(公告)日：2009-09-17
申请号：US12368484
申请日：2009-02-10
申请人： Xianglin ZHANG , Jieyang WU , Tadashi RENBUTSU , Shoji OKAZAKI , Yanshan HUANG
发明人： Xianglin ZHANG , Jieyang WU , Tadashi RENBUTSU , Shoji OKAZAKI , Yanshan HUANG
IPC分类号： G02F1/1333
CPC分类号： G02B7/1805 , H04N9/3105 , H04N9/315
摘要： A liquid crystal projection apparatus has an image synthesizing means comprising: a color synthesization prism having an upper surface, a lower surface facing the upper surface, and three light incident faces between the upper and lower surfaces; an upper prism pedestal provided on the upper surface of the color synthesization prism; a lower prism pedestal provided on the lower surface of the color synthesization prism; an upper liquid crystal panel holder provided on the upper prism pedestal and having a multiplicity of first jointing sections, a lower liquid crystal panel holder provided on the lower prism pedestal and having a multiplicity of second jointing sections; three liquid crystal panels; and three liquid crystal panel mounting members securely fixing thereon the three liquid crystal panels, the three mounting members arranged on the respective three incident faces of the color synthesization prism and adapted to joint the first jointing sections located in association with the respective incident faces to corresponding second jointing sections located in association with the corresponding incident faces. Thus, a liquid crystal projection apparatus is provided with such image synthesizing means having a reduced number of parts and an improved assembly accuracy.
摘要翻译：液晶投影装置具有图像合成装置，包括：具有上表面，与上表面相对的下表面和上表面和下表面之间的三个光入射面的颜色合成棱镜; 设置在彩色合成棱镜的上表面上的上棱镜基座; 设置在彩色合成棱镜的下表面上的下棱镜基座; 设置在上棱镜基座上并具有多个第一接合部的上液晶面板保持件，设置在下棱镜基座上的下液晶面板保持架，具有多个第二接合部; 三个液晶面板; 以及三个液晶面板安装部件，其牢固地固定在三个液晶面板上，三个安装部件被配置在彩色合成棱镜的三个入射面上，并且适于将与各个入射面相关联的第一接合部分接合到相应的第二个连接部分与相应的事件面相关联。因此，液晶投影装置设置有这样的图像合成装置，其具有减少的部件数量和改进的组装精度。

10. 发明申请

US20080055561A1 PROJECTOR APPARATUS 有权
标题翻译：投影仪
公开(公告)号：US20080055561A1
公开(公告)日：2008-03-06
申请号：US11850322
申请日：2007-09-05
申请人： Qiang LV , Xianglin ZHANG , Toshihiro SARUWATARI , Yanshan HUANG , Tadashi RENBUTSU , Shoji OKAZAKI , Xiangfei KONG , Wentian TANG
发明人： Qiang LV , Xianglin ZHANG , Toshihiro SARUWATARI , Yanshan HUANG , Tadashi RENBUTSU , Shoji OKAZAKI , Xiangfei KONG , Wentian TANG
IPC分类号： G03B21/16
CPC分类号： G03B21/16 , G03B21/145 , G03B21/22 , H04N9/3105 , H04N9/3144
摘要： The invention enables efficient cooling of: a light source providing source light; an optical system adapted to split the source light received from the light source into three primary colors R, G, and B; and a power supply unit for supplying electric power to various electric components installed in a casing of a projector apparatus. To do so, a first fan is arranged between the light source and the power supply unit such that its air inspiration face is directed to the power supply unit and its air expiration face is directed to the light source. Further, a second fan, adapted to inspire air from within the projector apparatus, is provided in the central area of the projector apparatus. On the air expiration side of the second fan is a cooling duct for cooling the light source and optical system. In addition, a third fan for cooling a G-LCP unit and an R-LCP unit of the image synthesizing device and a fourth fan for cooling a B-LCP and an R-LCP unit of the image synthesizing device are provided in such a way that the streams of air expired from said third and fourth fans intersect each other. The invention allows operation of a projector apparatus with a fewer fans, yet achieves suppression of exhaust air temperature and noise, and cost reduction as well.
摘要翻译：本发明能够有效地冷却：提供源光的光源; 适于将从光源接收的源光分成三原色R，G和B的光学系统; 以及用于向安装在投影仪装置的壳体中的各种电气部件供电的电源单元。为此，第一风扇布置在光源和电源单元之间，使得其空气吸入面被引导到电源单元，并且其空气呼出面朝向光源。此外，在投影仪装置的中央区域设置有适于在投影仪装置内启发空气的第二风扇。在第二风扇的空气呼出侧是用于冷却光源和光学系统的冷却管道。此外，用于冷却图像合成装置的G-LCP单元和R-LCP单元的第三风扇和用于冷却图像合成装置的B-LCP和R-LCP单元的第四风扇设置在从所述第三和第四风扇流过的空气流彼此相交的方式。本发明允许具有较少风扇的投影仪设备的操作，而且还实现排气温度和噪声的抑制以及降低成本。

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