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1. 发明专利

DK201900068U3 Stor Skala Nano replikation system 未知
公开(公告)号：DK201900068U3
公开(公告)日：2020-12-07
申请号：DKBA201900068
申请日：2019-09-03
申请人： HENRIK LINDSKOV , YAN XIA
发明人： HENRIK LINDSKOV , YAN XIA
IPC分类号： G03F7/00 , B29C59/02 , B82Y40/00
摘要： Den foreliggende opfindelse beskriver et Nano-replikationssystem med høj nøjagtighedsposition, som er nødvendig for fremstilling af nanostruktur ned stor nøjagtighed på et nyt underlag, herunder et dyssehoved med indvendig lyskilde og PDMS-skabelon, et objektunderlag, en høj præcisions arbejdsbænk med stor bevægelsesposition og nøjagtighed i både X- og Y-retning.

2. 发明专利

DK201900062U3 未知
公开(公告)号：DK201900062U3
公开(公告)日：2020-11-16
申请号：DKBA201900062
申请日：2019-08-14
申请人： DPL IND A/S , YAN XIA
发明人： YAN XIA , HENRIK LINDSKOV RASMUSSEN
IPC分类号： A01G33/00 , C12N1/12

3. 发明申请

US20210186648A1 SURGICAL SHAPE SENSING FIBER OPTIC APPARATUS AND METHOD THEREOF 有权
公开(公告)号：US20210186648A1
公开(公告)日：2021-06-24
申请号：US16754800
申请日：2018-10-10
申请人： Yan XIA , Lu LAN , VIBRONIX, INC.
发明人： Yan XIA , Lu LAN
IPC分类号： A61B90/00 , G06T7/20
摘要： A shape sensing apparatus for tissue and surgical procedures comprising a processing means and a tunable light source. At least one shape sensing fiber can be used with the shape sensing fiber having a plurality of individual sensing fiber cores having a fiber Bragg grating distributed within the fiber. An optical switch configured to sequentially switch between a multiplex of individual fibers inside the shape sensing fiber for signal detection can be included and a detector can be used to detect the fiber signals. An augmented reality system that receives the tracking data from the shape sensing apparatus, and superimposes visual guidance on its display for precise and intuitive surgical guidance.

4. 发明授权

US10157244B2 Model driven connection approximation for mechanical, electrical and plumbing drawings 有权
公开(公告)号：US10157244B2
公开(公告)日：2018-12-18
申请号：US14407196
申请日：2012-06-25
申请人： Henry Chen , Jiangeng Du , Xiaoli Wang , Yan Xia , Liana Maria Kiff
发明人： Henry Chen , Jiangeng Du , Xiaoli Wang , Yan Xia , Liana Maria Kiff
IPC分类号： G06F17/50 , G06T7/00 , G06K9/00
摘要： A system displays a raster-based or a vector-based formatted drawing on a user interface. A user selects a device on the drawing. The selected device is classified on a template. The drawing is searched for the classified template. Three-dimensional characteristics are imbued to the selected device. Connection types among different types of devices on the drawing are received into the system. A search is performed for all connection instances throughout the drawing using the received connection types. An object oriented and three-dimensionally, spatially referenced view of the drawing is generated on a user interface.

5. 发明申请

US20160024244A1 Periodic Nanostructures From Self Assembled Wedge-Type Block-Copolymers 审中-公开
公开(公告)号：US20160024244A1
公开(公告)日：2016-01-28
申请号：US14698520
申请日：2015-04-28
申请人： Yan XIA , Benjamin R. SVEINBJORNSSON , Robert H. GRUBBS , Raymond WEITEKAMP , Garret M. MIYAKE , Victoria PIUNOVA , Christopher Scot DAEFFLER
发明人： Yan XIA , Benjamin R. SVEINBJORNSSON , Robert H. GRUBBS , Raymond WEITEKAMP , Garret M. MIYAKE , Victoria PIUNOVA , Christopher Scot DAEFFLER
IPC分类号： C08G61/12
CPC分类号： C08G61/124 , B81C2201/0149 , B82Y40/00 , C08F222/04 , C08F222/40 , C08F232/08 , C08F293/00 , C08F299/00 , C08G61/08 , C08G81/00 , C08G2261/126 , C08G2261/128 , C08G2261/1426 , C08G2261/146 , C08G2261/148 , C08G2261/149 , C08G2261/3241 , C08G2261/3324 , C08G2261/418 , C08G2261/74
摘要： The invention provides a class of wedge-type block copolymers having a plurality of chemically different blocks, at least a portion of which incorporates a wedge group-containing block providing useful properties. For example, use of one or more wedge group-containing blocks in some block copolymers of the invention significantly inhibits chain entanglement and, thus, the present block copolymers materials provide a class of polymer materials capable of efficient molecular self-assembly to generate a range of structures, such as periodic nanostructures and microstructures. Materials of the present invention include copolymers having one or more wedge group-containing blocks, and optionally for some applications copolymers also incorporating one or more polymer side group-containing blocks. The present invention also provides useful methods of making and using wedge-type block copolymers.

6. 发明授权

US08907095B2 Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 有权
标题翻译：双环杂环衍生物及其作为GPR119活性调节剂的用途
公开(公告)号：US08907095B2
公开(公告)日：2014-12-09
申请号：US12739531
申请日：2008-10-20
申请人： Yan Xia , Craig D. Boyle , William J. Greenlee , Samuel Chackalamannil , Charles Lee Jayne
发明人： Yan Xia , Craig D. Boyle , William J. Greenlee , Samuel Chackalamannil , Charles Lee Jayne
IPC分类号： C07D221/02 , A61K31/439 , C07D451/14 , C07D491/08 , C07D495/08 , C07D471/08 , C07D451/06 , C07D487/08 , C07D401/14 , C07D498/08
CPC分类号： C07D451/06 , A61K31/439 , C07D401/14 , C07D451/14 , C07D471/08 , C07D487/08 , C07D491/08 , C07D495/08 , C07D498/08
摘要： The present invention relates to Bicyclic Heterocycle Derivatives, compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.
摘要翻译：本发明涉及双环杂环衍生物，包含双环杂环衍生物的组合物，以及使用双环杂环衍生物治疗或预防肥胖症，糖尿病，代谢紊乱，心血管疾病或与GPR119活性相关的病症的方法患者。

7. 发明授权

US08609676B2 4, 5, 6-trisubstituted pyrimidine derivatives as factor IXa inhibitors 有权
标题翻译： 4,5,6,6-三取代嘧啶衍生物作为因子IXa抑制剂
公开(公告)号：US08609676B2
公开(公告)日：2013-12-17
申请号：US13388628
申请日：2010-08-03
申请人： Mariappan V. Chelliah , Samuel Chackalamannil , William J. Greenlee , Keith Eagan , Zhuyan Guo , Martin C. Clasby , Yan Xia , Charles L. Jayne , Michael Dwyer , Kartik M. Keertikar , Tin-Yau Chan , Li Wang
发明人： Mariappan V. Chelliah , Samuel Chackalamannil , William J. Greenlee , Keith Eagan , Zhuyan Guo , Martin C. Clasby , Yan Xia , Charles L. Jayne , Michael Dwyer , Kartik M. Keertikar , Tin-Yau Chan , Li Wang
IPC分类号： A01N43/54 , A61K31/505
CPC分类号： C07D239/34 , C07D239/47 , C07D239/52 , C07D401/12 , C07D403/04 , C07D403/12 , C07D413/12 , C07D417/12
摘要： The present invention relates to novel heterocyclic compounds of Formulae (I): (Chemical formula should be inserted here as it appears on abstract in paper form) Formula (I) as disclosed herein, or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are pharmaceutical compositions comprising said compounds, and methods for using said compounds for treating or preventing a thromboembolic disorder.
摘要翻译：本发明涉及式（I）的新型杂环化合物：（化学式应在此插入，如本文摘要中所示）本文公开的式（I），或其药学上可接受的盐，溶剂合物，酯，前药或其立体异构体。还公开了包含所述化合物的药物组合物，以及使用所述化合物治疗或预防血栓栓塞性疾病的方法。

8. 发明申请

US20120242025A1 CLAMPING MECHANISM WITH DETACHABLE POSITIONING MEMBER 有权
标题翻译：具有可拆卸定位构件的夹紧机构
公开(公告)号：US20120242025A1
公开(公告)日：2012-09-27
申请号：US13225678
申请日：2011-09-06
申请人： XIAO-BING XU , SHAN-YAN XIA , ZHI-WEN WANG , QING-SONG WEN
发明人： XIAO-BING XU , SHAN-YAN XIA , ZHI-WEN WANG , QING-SONG WEN
IPC分类号： B23Q3/06
CPC分类号： B23Q3/06 , B23Q1/25
摘要： A clamping mechanism includes a positioning member, a support plate, a frame, a fastening assembly, and an operating assembly. The support plate defines a through hole. The fastening assembly is fixed to the frame. The fastening assembly includes a fastening member and an elastic member. The positioning member extends through the through hole of the support plate, and is fastened by the fastening member under an elastic force of the elastic member. The operating assembly resists the fastening member, thereby driving the fastening member away from the positioning member.
摘要翻译：夹紧机构包括定位构件，支撑板，框架，紧固组件和操作组件。支撑板限定了通孔。紧固组件固定在框架上。紧固组件包括紧固构件和弹性构件。定位构件延伸穿过支撑板的通孔，并在弹性构件的弹力下由紧固构件紧固。操作组件抵抗紧固构件，从而驱动紧固构件远离定位构件。

9. 发明申请

US20120235337A1 CLAMPING MECHANISM WITH DETACHABLE POSITION MEMBER 审中-公开
标题翻译：具有可拆卸位置构件的夹紧机构
公开(公告)号：US20120235337A1
公开(公告)日：2012-09-20
申请号：US13290006
申请日：2011-11-04
申请人： XIAO-BING XU , SHAN-YAN XIA , ZHI-WEN WANG , QING-SONG WEN
发明人： XIAO-BING XU , SHAN-YAN XIA , ZHI-WEN WANG , QING-SONG WEN
IPC分类号： B23Q3/06
CPC分类号： B25B5/08 , B25B5/06
摘要： A clamp mechanism includes a support plate, a frame, a positioning member, a resisting member, an operating assembly. The support plate defines an assembly hole. The frame is fixed to the support plate, and defines a positioning groove and a sliding groove. The positioning member extends through the assembly hole of the support plate, and received in the positioning groove. The operating assembly is connected to the resisting member. The resisting member is movably received in the sliding groove and opposite to the positioning member. The sliding groove has a first end adjacent to the positioning member and a second end away from the positioning member, such that the operating assembly drives the resisting member to move in the sliding groove from the second end to the first end, thereby clamping the positioning member in the positioning groove of the frame.
摘要翻译：夹紧机构包括支撑板，框架，定位构件，阻力构件，操作组件。支撑板限定了组装孔。框架固定在支撑板上，并且限定了定位槽和滑动槽。定位构件延伸穿过支撑板的组装孔，并被容纳在定位槽中。操作组件连接到电阻构件。抵抗构件可移动地容纳在滑动槽中并与定位构件相对。滑动槽具有与定位构件相邻的第一端和远离定位构件的第二端，使得操作组件驱动阻力构件在滑动槽中从第二端移动到第一端，从而夹紧定位构件在框架的定位槽中。

10. 发明授权

US08153664B2 Bicyclic and tricyclic derivatives as thrombin receptor antagonists 有权
标题翻译：双环和三环衍生物作为凝血酶受体拮抗剂
公开(公告)号：US08153664B2
公开(公告)日：2012-04-10
申请号：US11865793
申请日：2007-10-02
申请人： Samuel Chackalamannil , Mariappan V. Chelliah , Yuguang Wang , Yan Xia
发明人： Samuel Chackalamannil , Mariappan V. Chelliah , Yuguang Wang , Yan Xia
IPC分类号： C07D401/06 , A61K31/4439 , A61P7/02 , A61P7/12 , A61P9/10 , A61P29/00 , A61P19/02 , A61P3/10 , A61P3/14 , A61P11/06 , A61P11/08
CPC分类号： C07D401/06 , C07D417/06
摘要： Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salt or solvate of said compound, isomer or racemic mixture wherein represents an optional double bond, the dotted line is optionally a bond or no bond, resulting in a double bond or a single bond, as permitted by the valency requirement and wherein E, A, G M, Het, B, X, R3, R10, R11, R32 and R33 are herein defined and the remaining substituents are as defined in the specification, are disclosed, as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds. Combination therapy with other cardiovascular agents is also claimed.
摘要翻译：所述式的杂环取代三环或所述化合物，异构体或外消旋混合物的药学上可接受的盐或溶剂合物，其中代表任选的双键，虚线任选是键或无键，导致双键或单键，如价格要求所允许的，其中E，A，GM，Het，B，X，R 3，R 10，R 11，R 32和R 33在本文中定义，其余取代基如说明书中所定义，以及药物含有它们的组合物和通过施用所述化合物治疗与血栓形成，动脉粥样硬化，再狭窄，高血压，心绞痛，心律失常，心力衰竭和癌症相关的疾病的方法。还要求与其它心血管药物联合治疗。

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