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    • 3. 发明申请
    • GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION
    • 甘油三酯生产工艺和甘油酸低聚物
    • WO2002083661A1
    • 2002-10-24
    • PCT/JP2002/003570
    • 2002-04-10
    • KUREHA CHEMICAL INDUSTRY COMPANY, LIMITEDYAMANE, KazuyukiKAWAKAMI, Yukichika
    • YAMANE, KazuyukiKAWAKAMI, Yukichika
    • C07D319/12
    • C07D319/12
    • The invention relates to a glycolide production process wherein a depolymerization reaction system comprising a glycolic acid oligomer or a glycolic acid oligomer and a polar organic solvent is heated to depolymerize the glycolic acid oligomer into glycolide, the resulting glycolide or the glycolide and polar organic solvent are distilled out of the depolymerization reaction system, and the glycolide is recovered from distillates obtained by distillation. The glycolic acid oligomer or the glycolic acid oligomer and polar organic solvent are continuously or intermittently charged into the depolymerization reaction system, thereby carrying out depolymerization reactions continuously or repeatedly. During the depolymerization reactions, a compound having an alcoholic hydroxyl group is permitted to exist at a specific quantitative ratio in the depolymerization reaction system. The invention is also concerned with a glycolic acid oligomer for the production of glycolide, which is obtained by condensation of glycolic acid in the presence of the compound having an alcoholic hydroxyl group.
    • 本发明涉及一种乙交酯生产方法,其中加热包含乙醇酸低聚物或乙醇酸低聚物和极性有机溶剂的解聚反应体系,使乙醇酸低聚物解聚成乙交酯,得到的乙交酯或乙交酯和极性有机溶剂为 从解聚反应体系中蒸出,从蒸馏得到的馏出物中回收乙交酯。 将乙醇酸低聚物或乙醇酸低聚物和极性有机溶剂连续或间歇地加入到解聚反应体系中,从而连续或反复进行解聚反应。 在解聚反应中,在解聚反应体系中允许具有醇羟基的化合物以特定的定量比存在。 本发明还涉及通过乙醇酸在具有醇羟基的化合物的存在下缩合而获得的用于生产乙交酯的乙醇酸低聚物。
    • 4. 发明申请
    • GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION
    • 甘醇酸生产方法和甘醇酸组合物
    • WO02070508A3
    • 2002-12-19
    • PCT/JP0202025
    • 2002-03-05
    • KUREHA CHEMICAL IND CO LTDYAMANE KAZUYUKIKAWAKAMI YUKICHIKA
    • YAMANE KAZUYUKIKAWAKAMI YUKICHIKA
    • C07B61/00C07D319/12C08G63/08C08G63/00C08G63/06
    • C07D319/12C08G63/08
    • The invention provides a process for producing glycolide by depolymerization by heating of a glycolic acid oligomer in the presence or absence of a solvent, which process ensures stable depolymerization. The depolymerization reaction is carried out while the content of alkaline metal ions in a glycolic acid oligomer-containing depolymerization reaction system is controlled to 0.001% by mass or lower; a sulfate or an organic acid salt, each in the form of di- or poly-valent cations, or a mixture thereof is allowed to be present as a stabilizer in the depolymerization reaction system; or the content of alkaline metal ions in the depolymerization reaction system is controlled to 0.001% by mass or lower, and a sulfate or an organic acid salt, each in the form of di- or poly-valent cations, or a mixture thereof is allowed to be present as a stabilizer in the depolymerization reaction system.
    • 本发明提供了通过在存在或不存在溶剂的情况下通过加热乙醇酸低聚物进行解聚来生产乙交酯的方法,该方法确保了稳定的解聚。 解聚反应在将含有羟基乙酸低聚物的解聚反应体系中的碱金属离子的含量控制在0.001质量%以下的同时进行; 各自为二价或多价阳离子形式的硫酸盐或有机酸盐或其混合物允许在解聚反应体系中作为稳定剂存在; 或解聚反应体系中的碱金属离子的含量被控制为0.001质量%以下,并且允许各自以二价或多价阳离子形式或其混合物形式的硫酸盐或有机酸盐 在解聚反应体系中作为稳定剂存在。
    • 6. 发明申请
    • GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION
    • 甘油酯生产工艺和甘油酸组合物
    • WO2002070508A2
    • 2002-09-12
    • PCT/JP2002/002025
    • 2002-03-05
    • KUREHA KAGAKU KOGYO K.K.YAMANE, KazuyukiKAWAKAMI, Yukichika
    • YAMANE, KazuyukiKAWAKAMI, Yukichika
    • C07D319/12
    • C07D319/12C08G63/08
    • The invention provides a process for producing glycolide by depolymerization by heating of a glycolic acid oligomer in the presence or absence of a solvent, which process ensures stable depolymerization. The depolymerization reaction is carried out while the content of alkaline metal ions in a glycolic acid oligomer-containing depolymerization reaction system is controlled to 0.001% by mass or lower; a sulfate or an organic acid salt, each in the form of di- or poly-valent cations, or a mixture thereof is allowed to be present as a stabilizer in the depolymerization reaction system; or the content of alkaline metal ions in the depolymerization reaction system is controlled to 0.001% by mass or lower, and a sulfate or an organic acid salt, each in the form of di- or poly-valent cations, or a mixture thereof is allowed to be present as a stabilizer in the depolymerization reaction system.
    • 本发明提供通过在存在或不存在溶剂的情况下加热乙醇酸低聚物来解聚生产乙交酯的方法,该方法确保了稳定的解聚。 在使含乙醇酸低聚物的解聚反应体系中的碱金属离子的含量控制在0.001质量%以下的同时进行解聚反应; 在二聚或多价阳离子形式的硫酸盐或有机酸盐或其混合物作为稳定剂存在于解聚反应体系中; 或将解聚反应体系中的碱金属离子的含量控制为0.001质量%以下,并且允许分别为二价或多价阳离子形式的硫酸盐或有机酸盐或其混合物 作为解聚反应体系中的稳定剂存在。