专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08507848B1 Wire electrode based ion guide device 有权
标题翻译：线电极离子导向装置
公开(公告)号：US08507848B1
公开(公告)日：2013-08-13
申请号：US13357470
申请日：2012-01-24
申请人： Li Ding , Gongyu Jiang , Wenjian Sun
发明人： Li Ding , Gongyu Jiang , Wenjian Sun
IPC分类号： H01J49/42 , H01J49/34 , H01J49/04
CPC分类号： H01J49/065 , H01J49/066
摘要： This invention presents a kind of ion guide device comprising multiple layers of stretched wire electrodes crossing in space. These wire electrodes are distributed along a defined ion guiding axis in the ion guide device. Each layer of wire electrodes contains at least two wire electrodes with some distance away from the guiding axis, and rotates with an angle relative to wire electrodes on neighboring layer. The ion guide contains multiple layers of wire electrodes to form a cage-like ion guide tunnel and keeps the mounting framework of those wire electrodes outside of the ion guide tunnel, thus reducing the interference of the gas flows from the ion guide device. A power supply provides voltage to each layer of wire electrodes, creates an electric field which focuses the ions towards the guiding axis.
摘要翻译：本发明提供了一种离子导向装置，其包括在空间上交叉的多层拉伸线电极。这些线电极沿离子导向装置中限定的离子引导轴分布。每层线电极包含至少两根与引导轴距离一定距离的线电极，并相对于相邻层上的线电极以一定角度旋转。离子导向器包含多层线电极以形成笼状离子导向通道，并将这些线电极的安装框架保持在离子引导通道外部，从而减少离子导向装置的气流的干扰。电源为每层线电极提供电压，产生将离子聚焦到引导轴的电场。

2. 发明授权

US08384025B2 Device for separating, enriching and detecting ions 有权
标题翻译：用于分离，富集和检测离子的装置
公开(公告)号：US08384025B2
公开(公告)日：2013-02-26
申请号：US13130254
申请日：2009-11-26
申请人： Wenjian Sun , Li Ding
发明人： Wenjian Sun , Li Ding
IPC分类号： H01J49/26 , H01J49/42 , H01J49/10
CPC分类号： G01N27/622 , G01N15/0266
摘要： A device for separating, enriching and detecting ions comprises: a gas tube, in which a carrier gas flows at a uniform rate; an ion source; multiple electrodes provided in the gas tube and applied with electric voltages respectively, so that at least an electric field is produced along the axis of the gas tube; an ion detector; and an ion extraction channel, by which specific enriched ions will be guided across the side wall of the gas tube toward the ion detector and be analyzed. The device enriches ions utilizing the following characteristic: compound ions with specific ion mobility maintain a dynamic balance for a period of time in a flow field under the combination of a carrier gas and a suitable electrical field against the direction of the carrier gas. Simultaneously, multiple compound particles with different ion motilities can be separated and enriched at positions with different electrical field intensities in a flow field in the same manner. The device also comprises synchronously export latitudinally enriched ions at different positions in a flow field, and performs later mass analysis using a mass spectrometer.
摘要翻译：用于分离，富集和检测离子的装置包括：气体管，其中载气以均匀的速率流动; 离子源; 设置在气体管中并分别施加电压的多个电极，使得沿着气体管的轴线产生至少一个电场; 离子检测器和离子提取通道，通过该离子提取通道将特定的富集离子引导穿过气体管的侧壁朝离子检测器进行分析。该装置利用以下特征丰富离子：具有特定离子迁移率的复合离子在载气和合适的电场相对于载气方向的组合下在流场中保持动态平衡一段时间。同时，具有不同离子运动的多种化合物颗粒可以以相同的方式在流场中分离富集在具有不同电场强度的位置。该装置还包括在流场中同步输出纬向富集的离子，并使用质谱仪进行质量分析。

3. 发明申请

US20120037797A1 DESORPTION AND IONIZATION METHOD AND DEVICE 有权
标题翻译：解吸和离子化方法及装置
公开(公告)号：US20120037797A1
公开(公告)日：2012-02-16
申请号：US13265638
申请日：2010-04-12
申请人： Ding Li , Wenjian Sun
发明人： Ding Li , Wenjian Sun
IPC分类号： H01J49/04 , H01J49/00
CPC分类号： H01J49/04 , G01N27/62 , H01J49/049
摘要： The present invention involves a method and a device for sequentially desorbing and ionizing mixed analytes on a solid surface with a gradual temperature scan, and continuously collecting data for multiple times in the gradual desorption and ionization process. By gradually increase the temperature of at least one part of the sample, the analytes with different thermal desorption capabilities are sequentially desorbed from surfaces of the solid sample, thereby providing a sample pre-separation scheme, so as to reduce difficulties to subsequent mass spectrum detection. Meanwhile, since mass spectrum data of the analytes with different boiling points is collected for multiple times during a temperature scan, the analytes with a low boiling point can be detected first at lower temperature in order to avoid rapid exhaustion at higher temperature, thereby improving the detection efficiency of the analytes with low boiling points.
摘要翻译：本发明涉及一种用于在逐渐温度扫描下在固体表面上顺次解吸和电离混合分析物的方法和装置，并且在逐渐解吸和电离过程中连续收集数据多次。通过逐渐增加样品的至少一部分的温度，具有不同热解吸能力的分析物从固体样品的表面顺序解吸，从而提供样品预分离方案，以减少后续质谱检测的困难。同时，由于在温度扫描期间多次收集沸点不同的分析物的质谱数据，所以可以在较低的温度下首先检测低沸点的分析物，以避免在较高的温度下快速耗尽，从而改善低沸点分析物的检测效率。

4. 发明申请

US20110253903A1 DEVICE FOR DESORPTION IONIZATION 有权
标题翻译：用于解吸离子的装置
公开(公告)号：US20110253903A1
公开(公告)日：2011-10-20
申请号：US13141864
申请日：2009-12-29
申请人： Wenjian Sun , Xiaohui Yang , Li Ding
发明人： Wenjian Sun , Xiaohui Yang , Li Ding
IPC分类号： H01J27/08
CPC分类号： H01J49/168
摘要： The current invention involves a desorption corona beam ionization source/device for analyzing samples under atmospheric pressure without sample pretreatment. It includes a gas source, a gas flow tube, a gas flow heater, a metal tube, a DC power supply and a sample support/holder for placing the samples. A visible corona beam is formed at a sharply pointed tip at the exit of the metal tube when a stream of inert gas flows through the metal tube that is applied with a high DC voltage. The gas is heated for desorbing the analyte from solid samples and the desorbed species are ionized by the energized particles embedded in the corona beam. The ions formed are then transferred through an adjacent inlet into a mass spectrometer or other devices capable of analyzing ions. Visibility of the corona beam in the current invention greatly facilitates pinpointing a sampling area on the analyte and also makes profiling of sample surfaces possible.
摘要翻译：本发明涉及一种解吸电晕束电离源/装置，用于在大气压力下分析样品而无需样品预处理。其包括气体源，气体流管，气流加热器，金属管，直流电源和用于放置样品的样品支撑/保持器。当惰性气体流过施加有高直流电压的金属管时，在金属管的出口处的尖锐尖端处形成可见的电晕束。加热气体以从固体样品中解吸分析物，并且解吸物质被嵌入电晕束中的通电颗粒电离。所形成的离子然后通过相邻入口转移到质谱仪或其他能够分析离子的装置中。本发明中电晕束的可见性大大有助于精确分析分析物上的采样区域，并且还使得样品表面的轮廓成为可能。

5. 发明申请

US20130026359A1 METHOD AND APPARATUS FOR GENERATING AND ANALYZING IONS 有权
标题翻译：用于产生和分析离子的方法和装置
公开(公告)号：US20130026359A1
公开(公告)日：2013-01-31
申请号：US13634190
申请日：2011-04-22
申请人： Sumio Kumashiro , Wenjian Sun , Li Ding
发明人： Sumio Kumashiro , Wenjian Sun , Li Ding
IPC分类号： H01J49/26 , H01J49/04 , H01J49/16
CPC分类号： H01J49/10 , G01N27/622 , H01J49/066 , H01J49/161 , H01J49/164 , H01J49/165 , H01J49/24
摘要： The current invention involves a method and a device for generating and analyzing ions in order to analyze samples directly without sample preparation. The gaseous neutral molecules are desorbed under atmospheric pressure by a desorption method. The desorbed neutral molecules are then transferred into a low pressure region where they are post-ionized by a mist from an electrospray probe tip or by photons from a vacuum UV source. The generated ions are then focused in a time varying electric field in the low pressure chamber before they are transferred into a mass spectrometer or ion mobility spectrometer for further analysis.
摘要翻译：本发明涉及用于生成和分析离子的方法和装置，以便在不进行样品制备的情况下直接分析样品。气态中性分子通过解吸法在大气压下解吸。然后将解吸的中性分子转移到低压区域，在那里它们被来自电喷雾探针尖端的雾或者来自真空UV源的光子后离子化。然后将所产生的离子聚焦在低压室中的时变电场中，然后将其转移到用于进一步分析的质谱仪或离子迁移谱仪中。

6. 发明申请

US20110049352A1 ION SOURCE 有权
标题翻译：离子源
公开(公告)号：US20110049352A1
公开(公告)日：2011-03-03
申请号：US12552476
申请日：2009-09-02
申请人： Li Ding , Wenjian Sun
发明人： Li Ding , Wenjian Sun
IPC分类号： H01J49/16 , H01J49/26
CPC分类号： H01J49/162 , H01J49/0463 , H01J49/165
摘要： This invention relates to a desorpton/ionization source operated under ambient conditions for direct analysis of solid or liquid samples on a surface. The source comprises of a laser desorption system and a UV/electrospray combined ionization system. The source is suitable for simultaneously ionizing samples with different polarity in a complex mixture. At the same time, the compact design of the source with multiple channels can maintain the level of local concentration of the analyte ions inside the source for higher efficiency of sample ionization and introduction.
摘要翻译：本发明涉及在环境条件下操作的用于在表面上直接分析固体或液体样品的解吸/离子源。该源包括激光解吸系统和UV /电喷雾组合电离系统。该源适用于在复杂混合物中同时电离不同极性的样品。同时，具有多个通道的源的紧凑设计可以保持源内的分析物离子的局部浓度水平，以提高样品电离和引入的效率。

7. 发明授权

US08704170B2 Method and apparatus for generating and analyzing ions 有权
标题翻译：用于产生和分析离子的方法和装置
公开(公告)号：US08704170B2
公开(公告)日：2014-04-22
申请号：US13634190
申请日：2011-04-22
申请人： Sumio Kumashiro , Wenjian Sun , Li Ding
发明人： Sumio Kumashiro , Wenjian Sun , Li Ding
IPC分类号： H01J49/00 , H01J49/10 , H01J49/24 , H01J49/16
CPC分类号： H01J49/10 , G01N27/622 , H01J49/066 , H01J49/161 , H01J49/164 , H01J49/165 , H01J49/24
摘要： The current invention involves a method and a device for generating and analyzing ions in order to analyze samples directly without sample preparation. The gaseous neutral molecules are desorbed under atmospheric pressure by a desorption method. The desorbed neutral molecules are then transferred into a low pressure region where they are post-ionized by a mist from an electrospray probe tip or by photons from a vacuum UV source. The generated ions are then focused in a time varying electric field in the low pressure chamber before they are transferred into a mass spectrometer or ion mobility spectrometer for further analysis.
摘要翻译：本发明涉及用于生成和分析离子的方法和装置，以便在不进行样品制备的情况下直接分析样品。气态中性分子通过解吸法在大气压下解吸。然后将解吸的中性分子转移到低压区域，在那里它们被来自电喷雾探针尖端的雾或者来自真空UV源的光子后离子化。然后将所产生的离子聚焦在低压室中的时变电场中，然后将其转移到用于进一步分析的质谱仪或离子迁移谱仪中。

8. 发明申请

US20130187044A1 A WIRE ELECTRODE BASED ION GUIDE DEVICE 有权
标题翻译：一种基于导线电极的导线装置
公开(公告)号：US20130187044A1
公开(公告)日：2013-07-25
申请号：US13357470
申请日：2012-01-24
申请人： LI DING , GONGYU JIANG , WENJIAN SUN
发明人： LI DING , GONGYU JIANG , WENJIAN SUN
IPC分类号： H01J49/22
CPC分类号： H01J49/065 , H01J49/066
摘要： This invention presents a kind of ion guide device comprising multiple layers of stretched wire electrodes crossing in space. These wire electrodes are distributed along a defined ion guiding axis in the ion guide device. Each layer of wire electrodes contains at least two wire electrodes with some distance away from the guiding axis, and rotates with an angle relative to wire electrodes on neighboring layer. The ion guide contains multiple layers of wire electrodes to form a cage-like ion guide tunnel and keeps the mounting framework of those wire electrodes outside of the ion guide tunnel, thus reducing the interference of the gas flows from the ion guide device. A power supply provides voltage to each layer of wire electrodes, creates an electric field which focuses the ions towards the guiding axis.
摘要翻译：本发明提供了一种离子导向装置，其包括在空间上交叉的多层拉伸线电极。这些线电极沿离子导向装置中限定的离子引导轴分布。每层线电极包含至少两根与引导轴距离一定距离的线电极，并相对于相邻层上的线电极以一定角度旋转。离子导向器包含多层线电极以形成笼状离子导向通道，并将这些线电极的安装框架保持在离子引导通道外部，从而减少离子导向装置的气流的干扰。电源为每层线电极提供电压，产生将离子聚焦到引导轴的电场。

9. 发明授权

US08242459B2 Device for desorption and ionization 有权
标题翻译：解吸和电离装置
公开(公告)号：US08242459B2
公开(公告)日：2012-08-14
申请号：US13141864
申请日：2009-12-29
申请人： Wenjian Sun , Xiaohui Yang , Li Ding
发明人： Wenjian Sun , Xiaohui Yang , Li Ding
IPC分类号： H01J27/08 , H01J49/04 , H05H1/24
CPC分类号： H01J49/168
摘要： The current invention involves a desorption corona beam ionization source/device for analyzing samples under atmospheric pressure without sample pretreatment. It includes a gas source, a gas flow tube, a gas flow heater, a metal tube, a DC power supply and a sample support/holder for placing the samples. A visible corona beam is formed at a sharply pointed tip at the exit of the metal tube when a stream of inert gas flows through the metal tube that is applied with a high DC voltage. The gas is heated for desorbing the analyte from solid samples and the desorbed species are ionized by the energized particles embedded in the corona beam. The ions formed are then transferred through an adjacent inlet into a mass spectrometer or other devices capable of analyzing ions. Visibility of the corona beam in the current invention greatly facilitates pinpointing a sampling area on the analyte and also makes profiling of sample surfaces possible.
摘要翻译：本发明涉及一种解吸电晕束电离源/装置，用于在大气压力下分析样品而无需样品预处理。其包括气体源，气体流管，气流加热器，金属管，直流电源和用于放置样品的样品支撑/保持器。当惰性气体流过施加有高直流电压的金属管时，在金属管的出口处的尖锐尖端处形成可见的电晕束。加热气体以从固体样品中解吸分析物，并且解吸物质被嵌入电晕束中的通电颗粒电离。所形成的离子然后通过相邻入口转移到质谱仪或其他能够分析离子的装置中。本发明中电晕束的可见性大大有助于精确分析分析物上的采样区域，并且还使得样品表面的轮廓成为可能。

10. 发明申请

US20110220790A1 DEVICE FOR SEPARATING, ENRICHING AND DETECTING IONS 有权
标题翻译：用于分离，增强和检测离子的装置
公开(公告)号：US20110220790A1
公开(公告)日：2011-09-15
申请号：US13130254
申请日：2009-11-26
申请人： Wenjian Sun , Li Ding
发明人： Wenjian Sun , Li Ding
IPC分类号： H01J49/22
CPC分类号： G01N27/622 , G01N15/0266
摘要： A device for separating, enriching and detecting ions comprises: a gas tube, in which a carrier gas flows at a uniform rate; an ion source; multiple electrodes provided in the gas tube and applied with electric voltages respectively, so that at least an electric field is produced along the axis of the gas tube; an ion detector; and an ion extraction channel, by which specific enriched ions will be guided across the side wall of the gas tube toward the ion detector and be analyzed. The device enriches ions utilizing the following characteristic: compound ions with specific ion mobility maintain a dynamic balance for a period of time in a flow field under the combination of a carrier gas and a suitable electrical field against the direction of the carrier gas. Simultaneously, multiple compound particles with different ion motilities can be separated and enriched at positions with different electrical field intensities in a flow field in the same manner. The device also comprises synchronously export latitudinally enriched ions at different positions in a flow field, and performs later mass analysis using a mass spectrometer.
摘要翻译：用于分离，富集和检测离子的装置包括：气体管，其中载气以均匀的速率流动; 离子源; 设置在气体管中并分别施加电压的多个电极，使得沿着气体管的轴线产生至少一个电场; 离子检测器和离子提取通道，通过该离子提取通道将特定的富集离子引导穿过气体管的侧壁朝离子检测器进行分析。该装置利用以下特征丰富离子：具有特定离子迁移率的复合离子在载气和合适的电场相对于载气方向的组合下在流场中保持动态平衡一段时间。同时，具有不同离子运动的多种化合物颗粒可以以相同的方式在流场中分离富集在具有不同电场强度的位置。该装置还包括在流场中同步输出纬向富集的离子，并使用质谱仪进行质量分析。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式