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1. 发明授权

US07182727B2 Single port cardiac support apparatus 失效
标题翻译：单口心脏支持装置
公开(公告)号：US07182727B2
公开(公告)日：2007-02-27
申请号：US11057273
申请日：2005-02-11
申请人： Walid Najib Aboul-Hosn
发明人： Walid Najib Aboul-Hosn
IPC分类号： A61M1/10
CPC分类号： A61M1/122 , A61M1/1008 , A61M1/101 , A61M1/1034 , A61M1/1086 , A61M1/125 , A61M25/1011 , A61M2205/32 , A61M2205/3334
摘要： A minimal intrusive cardiac support apparatus is disclosed which requires only one incision into a main blood vessel or heart chamber. The apparatus includes a pair of generally coaxial and slideably arranged cannulae (one inner and one outer) communicatively coupled to a blood pump for providing right-heart and/or left-heart cardiac support during cardiac surgery. Optional balloons may be mounted on the outside of the inner and outer conduits which can be selectively inflated to seal off the sides surrounding vessel or to deliver cooling fluid or medication to the surrounding tissue. Using the apparatus, a method of pumping blood through the body is also disclosed.
摘要翻译：公开了一种最小的侵入性心脏支持装置，其仅需要一个切口进入主血管或心室。该装置包括一对通常同轴且可滑动地布置的套管（一个内部和一个外部），其通信地联接到血液泵，用于在心脏手术期间提供右心脏和/或左心脏心脏支架。可选择的气球可以安装在内部和外部导管的外侧上，该导管可以选择性地膨胀以密封容器周围的侧面或将冷却流体或药物输送到周围组织。还公开了一种通过身体抽血的方法。

2. 发明授权

US06395026B1 Apparatus and methods for beating heart bypass surgery 失效
标题翻译：跳动心脏旁路手术的装置和方法
公开(公告)号：US06395026B1
公开(公告)日：2002-05-28
申请号：US09079836
申请日：1998-05-15
申请人： Walid Najib Aboul-Hosn , William Russell Kanz
发明人： Walid Najib Aboul-Hosn , William Russell Kanz
IPC分类号： A61M110
CPC分类号： A61M1/1034 , A61M1/1008 , A61M1/101 , A61M1/122 , A61M1/125
摘要： Pump and cannula systems inserted through the right side and/or left side of the heart provide protection against collapse of the heart chambers and veins and arteries and provide supplemental blood flow through same to enable beating heart bypass surgery on all vessels of the heart, including lateral and posterior vessels. The invention eliminates the use of cardiopulmonary bypass (CPB) machines. The invention further provides stents adapted for protecting from vein, artery, atrium and/or ventricle collapse during beating heart bypass surgery.
摘要翻译：通过心脏的右侧和/或左侧插入的泵和套管系统提供防止心室和静脉和动脉的塌陷的保护，并且通过其提供补充血液流动，以便能够在心脏的所有血管上进行心脏旁路手术，包括外侧和后侧血管。本发明消除了使用体外循环（CPB）机器。本发明还提供了适于在搏动心脏旁路手术期间保护静脉，动脉，心房和/或心室塌陷的支架。

3. 发明授权

US07381179B2 Pulmonary and circulatory blood flow support devices and methods for heart surgery procedures 失效
标题翻译：肺和循环血流支持装置和心脏手术程序的方法
公开(公告)号：US07381179B2
公开(公告)日：2008-06-03
申请号：US11136126
申请日：2005-05-24
申请人： Walid Najib Aboul-Hosn , William Russell Kanz
发明人： Walid Najib Aboul-Hosn , William Russell Kanz
IPC分类号： A61N1/362
CPC分类号： A61F2/82 , A61M1/1008 , A61M1/101 , A61M1/1034 , A61M1/122 , A61M1/125 , G06F19/00
摘要： Pump and cannula systems inserted through the right side and/or left side of the heart provide protection against collapse of the heart chambers and veins and arteries and provide supplemental blood flow through same to enable beating heart or still heart surgery, such as bypass surgery, on all vessels of the heart, including lateral and posterior vessels. Pump and cannula systems are provided for supporting pulmonary and/or circulatory blood flow external of the heart during any beating heart or still heart surgical procedure, including value repair or replacement. The invention eliminates the use of cardiopulmonary bypass (CPB) machines in all heart surgery and utilizes the patient's lung(s) for providing oxygenated blood during heart surgery. The invention further provides stents adapted for protecting from vein, artery, atrium and/or ventricle collapse during beating heart bypass surgery.
摘要翻译：通过心脏的右侧和/或左侧插入的泵和套管系统提供防止心室和静脉和动脉的塌陷的保护，并且通过它们提供补充的血液流动，以使得能够打心脏或静止心脏手术，例如旁路手术，在心脏的所有血管上，包括外侧和后侧血管。提供泵和套管系统，用于在任何跳动的心脏或静止心脏手术过程中支持心脏外部的肺和/或循环血流，包括价值修复或更换。本发明消除了在所有心脏手术中使用体外循环（CPB）机器，并利用患者的肺在心脏手术期间提供含氧血液。本发明还提供了适于在搏动心脏旁路手术期间保护静脉，动脉，心房和/或心室塌陷的支架。

4. 发明授权

US06613008B2 Integrated system for cardiopulmonary bypass and related methods 失效
公开(公告)号：US06613008B2
公开(公告)日：2003-09-02
申请号：US09877488
申请日：2001-06-08
申请人： Walid Najib Aboul-Hosn , Scott Youmans
发明人： Walid Najib Aboul-Hosn , Scott Youmans
IPC分类号： A61M3700
CPC分类号： A61M1/1698 , A61M1/1006 , A61M1/101 , A61M1/1034 , A61M1/1039 , A61M1/1086 , A61M1/3621 , A61M1/3666 , A61M1/3667 , A61M2205/3334 , A61M2209/082
摘要： An improved cardiopulmonary bypass system which consolidates and miniaturizes the entire CPB circuit on an integrated panel or box-type structure capable of being positioned within (or closely adjacent to) the sterile surgical field.

5. 发明授权

US06210397B1 Sealing cannula device 有权
标题翻译：密封套管装置
公开(公告)号：US06210397B1
公开(公告)日：2001-04-03
申请号：US09229806
申请日：1999-01-13
申请人： Walid Najib Aboul-Hosn , William Russell Kanz , Roland W. Ziegler
发明人： Walid Najib Aboul-Hosn , William Russell Kanz , Roland W. Ziegler
IPC分类号： A61M2516
CPC分类号： A61B17/3423 , A61B2017/3484 , A61B2017/349 , A61B2017/3492 , A61M25/02 , A61M2025/0079 , A61M2025/0233 , A61M2025/028
摘要： This invention relates to a sealing cannula device which can be easily and properly inserted while effectively sealing an incision made during a surgical or non-surgical process. The sealing cannula device includes a cannula sleeve having an external flange and tissue engaging threads. The screw threads on the external surface of the cannula sleeve allows the device to be easily screwed through an incision made in a body cavity wall or blood vessel until the tissue abuts against the flange. The vessel or body cavity wall is compressed between the flange and a flat surface formed by the helical thread. An effective compression seal is formed between the device and cavity or vessel wall which protects the puncture site from environmental contaminants. An axial through hole in the device provides vascular or body cavity access during surgical or non-surgical procedures.
摘要翻译：本发明涉及一种密封套管装置，其可以容易且适当地插入，同时有效地密封在手术或非外科手术过程中制成的切口。密封套管装置包括具有外部凸缘和组织接合螺纹的套管套管。套管套管外表面上的螺纹允许装置容易地通过在体腔壁或血管中形成的切口旋拧，直到组织抵靠凸缘。容器或体腔壁在凸缘和由螺旋形螺纹形成的平坦表面之间被压缩。在装置和腔或容器壁之间形成有效的压缩密封，其保护穿刺部位免受环境污染物的影响。装置中的轴向通孔在手术或非外科手术过程中提供血管或体腔通路。

6. 发明授权

US06858001B1 Single port cardiac support apparatus 失效
标题翻译：单口心脏支持装置
公开(公告)号：US06858001B1
公开(公告)日：2005-02-22
申请号：US09669104
申请日：2000-09-25
申请人： Walid Najib Aboul-Hosn
发明人： Walid Najib Aboul-Hosn
IPC分类号： A61M25/00 , A61B18/18 , A61B19/00 , A61M1/10 , A61M1/36 , A61M3/00 , A61M5/00 , A61M25/16
CPC分类号： A61M1/3653 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1086 , A61M1/122 , A61M1/125 , A61M1/3659 , A61M2205/32 , A61M2205/3334 , Y10S415/90
摘要： A minimal intrusive cardiac support apparatus is disclosed which requires only one incision into a main blood vessel or heart chamber. The apparatus includes a pair of generally coaxial and slideably arranged cannulae (one inner and one outer) communicatively coupled to a blood pump for providing right-heart and/or left-heart cardiac support during cardiac surgery. Optional balloons may be mounted on the outside of the inner and outer conduits which can be selectively inflated to seal off the sides surrounding vessel or to deliver cooling fluid or medication to the surrounding tissue. Using the apparatus, a method of pumping blood through the body is also disclosed.
摘要翻译：公开了一种最小的侵入性心脏支持装置，其仅需要一个切口进入主血管或心室。该装置包括一对通常同轴且可滑动地布置的插管（一个内部和一个外部），其通信地联接到血液泵，用于在心脏手术期间提供右心脏和/或左心脏心脏支架。可选择的气球可以安装在内部和外部导管的外侧上，该导管可以选择性地膨胀以密封周围容器的侧面或将冷却流体或药物输送到周围组织。还公开了一种通过身体抽血的方法。

7. 发明授权

US06532964B2 Pulmonary and circulatory blood flow support devices and methods for heart surgery procedures 有权
公开(公告)号：US06532964B2
公开(公告)日：2003-03-18
申请号：US09231320
申请日：1999-01-13
申请人： Walid Najib Aboul-Hosn , William Russell Kanz
发明人： Walid Najib Aboul-Hosn , William Russell Kanz
IPC分类号： A61B1900
CPC分类号： A61F2/82 , A61M1/1008 , A61M1/101 , A61M1/1034 , A61M1/122 , A61M1/125 , G06F19/00
摘要： Pump and cannula systems inserted through the right side and/or left side of the heart provide protection against collapse of the heart chambers and veins and arteries and provide supplemental blood flow through same to enable beating heart bypass surgery on all vessels of the heart, including lateral and posterior vessels. The invention eliminates the use of cardiopulmonary bypass (CPB) machines. The invention further provides stents adapted for protecting from vein, artery, atrium and/or ventricle collapse during beating heart bypass surgery.

8. 发明授权

US06210133B1 Blood pump with sterile motor housing 失效
标题翻译：血泵带无菌电机外壳
公开(公告)号：US06210133B1
公开(公告)日：2001-04-03
申请号：US09166135
申请日：1998-09-30
申请人： Walid Najib Aboul-Hosn , Sedig Noor , William Russell Kanz , Michael Guidera , Robert G. Matheny , Kelly J. McCrystle
发明人： Walid Najib Aboul-Hosn , Sedig Noor , William Russell Kanz , Michael Guidera , Robert G. Matheny , Kelly J. McCrystle
IPC分类号： F04B3504
CPC分类号： F04D29/628 , A61M1/101 , A61M1/1029 , A61M1/1036 , A61M1/122 , A61M1/127 , A61M2205/8243 , F04D13/06 , H02K1/185 , H02K5/128
摘要： A blood pump for use in CPB and other heart surgeries includes a reusable motor stator element which is enclosed in a disposable, sterile pump housing. The reusable, non-sterilized motor stator element is completely encased by the pump housing so that the motor stator can be reused without sterilization. The sterile housing allows the blood pump to be placed closed to the patient and within the sterile surgical field. The placement of the blood pump close to the heart during heart surgery greatly reduces the priming volume of the system thereby reducing the amount of saline or drugs which are introduced the patient's blood. The sterile housing may be evacuated to reduce the risk of emboli which may occur due to the failure of a seal.
摘要翻译：用于CPB和其他心脏手术的血泵包括可重复使用的电动机定子元件，其被封装在一次性无菌泵壳体中。可重复使用的，无消毒的电动机定子元件被泵壳完全包住，使得电动机定子可以在不进行灭菌的情况下重复使用。无菌外壳允许将血泵放置在患者身体和无菌手术区域内。在心脏手术期间将血泵置于心脏附近大大降低了系统的引发体积，从而减少引入患者血液的盐水或药物的量。无菌外壳可以被抽空以减少由于密封失败而可能发生的栓塞的风险。

9. 发明授权

US08540615B2 Left and right side heart support 有权
标题翻译：左右右心支持
公开(公告)号：US08540615B2
公开(公告)日：2013-09-24
申请号：US12846366
申请日：2010-07-29
申请人： Walid Najib Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
发明人： Walid Najib Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
IPC分类号： A61M25/00
CPC分类号： A61M1/3621 , A61M1/1008 , A61M1/101 , A61M1/1096 , A61M1/12 , A61M1/122 , A61M1/3663
摘要： A cannulation system for cardiac support uses an inner cannula disposed within an outer cannula. The outer cannula includes a fluid inlet for placement within the right atrium of a heart. The inner cannula includes a fluid inlet extending through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart. The cannulation system also employs a pumping assembly coupled to the inner and outer cannulas to withdraw blood from the right atrium for delivery to the pulmonary artery to provide right heart support, or to withdraw blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support, or both.
摘要翻译：用于心脏支架的插管系统使用设置在外套管内的内套管。外套管包括用于放置在心脏右心房内的流体入口。内套管包括延伸穿过外套管和心房隔膜的流体入口的流体入口，用于放置在心脏的左心房和左心室中的至少一个中。插管系统还采用耦合到内插管和外插管的抽吸组件，以从右心房抽取血液以递送到肺动脉以提供正确的心脏支持，或者从左心房和左心室中的至少一个抽出血液输送到主动脉以提供左心脏支持，或两者兼而有之。

10. 发明授权

US6152704A Blood pump with turbine drive 失效
标题翻译：血泵与涡轮驱动
公开(公告)号：US6152704A
公开(公告)日：2000-11-28
申请号：US164396
申请日：1998-09-30
申请人： Walid Najib Aboul-Hosn , Kelly McCrystle , Desmond O'Connell
发明人： Walid Najib Aboul-Hosn , Kelly McCrystle , Desmond O'Connell
IPC分类号： A61M1/10 , F04D13/02 , F04D13/04 , F04D29/62 , F04B17/00
CPC分类号： F04D29/628 , A61M1/101 , A61M1/1036 , F04D13/027 , F04D13/04
摘要： A blood pump for use in CPB and other heart surgeries includes a sterilizable blood pump removably attached to a turbine drive unit. An impeller within the fully enclosed and sterile blood pump moves the blood from the pump inlet to the pump outlet. The pump snaps onto the turbine drive unit and a magnetic coupling between the pump and the drive unit is used to transmit the rotation of a turbine shaft to the pump impeller. The turbine drive unit is preferably a sterilizable unit which may be placed directly in the sterile surgical field. The blood pump with turbine drive allows the blood pump to be placed close to the surgical site and minimizes the length of the tubing required for connecting the pump to the patient.
摘要翻译：用于CPB和其他心脏手术的血泵包括可移除地连接到涡轮驱动单元的可消毒血液泵。全封闭和无菌血液泵内的叶轮将血液从泵入口移动到泵出口。泵吸附在涡轮驱动单元上，泵和驱动单元之间的磁耦合用于将涡轮轴的旋转传递到泵叶轮。涡轮驱动单元优选是可直接放置在无菌外科手术领域中的可灭菌单元。具有涡轮驱动器的血泵允许将血泵放置在靠近外科手术部位，并将泵连接到病人所需的管道的长度最小化。

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