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1. 发明申请

WO2011150377A3 WAVEFORM SHAPES FOR TREATING NEUROLOGICAL DISORDERS OPTIMIZED FOR ENERGY EFFICIENCY 审中-公开
标题翻译：用于治疗优化能量效能的神经病变的波形
公开(公告)号：WO2011150377A3
公开(公告)日：2012-02-02
申请号：PCT/US2011038416
申请日：2011-05-27
申请人： NDI MEDICAL LLC , GRILL WARREN M , WONGSARNPIGOON AMORN
发明人： GRILL WARREN M , WONGSARNPIGOON AMORN
IPC分类号： A61N1/36
CPC分类号： A61N1/36146 , A61N1/0529 , A61N1/3606 , A61N1/36175
摘要： Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency.
摘要翻译：用于刺激神经组织的系统和方法应用由开发的遗传算法（GA）导出的刺激波形，其可以耦合到哺乳动物有髓轴突的细胞外刺激的计算模型。该波形针对能量效率进行了优化。

2. 发明申请

WO2013022840A1 SYSTEMS FOR AND METHODS OF TRANSCRANIAL DIRECT CURRENT ELECTRICAL STIMULATION 审中-公开
标题翻译：交叉直接电流刺激的系统和方法
公开(公告)号：WO2013022840A1
公开(公告)日：2013-02-14
申请号：PCT/US2012/049756
申请日：2012-08-06
申请人： NDI MEDICAL, LLC , WONGSARNPIGOON, Amorn , BOGGS, Joseph, W., II , RUBIN, Stuart, F. , SAKAI, Jonathan, L.
发明人： WONGSARNPIGOON, Amorn , BOGGS, Joseph, W., II , RUBIN, Stuart, F. , SAKAI, Jonathan, L.
IPC分类号： A61N1/00
CPC分类号： A61N1/36025 , A61N1/0456 , A61N1/0484 , A61N1/36021 , A61N1/361
摘要： A system according to the present invention provides a portable, non-invasive device adapted to deliver electrical stimulation to a brain, such as to treat tinnitus. Such system is preferably a head-worn system configured to provide transcranial direct current electrical stimulation (tDCS) to a patient, where a therapy based at least partially thereon may be self- administered by the patient. tDCS is a non-invasive method of brain stimulation to treat tinnitus, or other neurological indications, that may provide significant relief. Methods according to the present invention include preferably brief sessions of anodal tDCS to assist in determining adequate electrode location and stimulus intensity by producing transient decreases in tinnitus intensity. Methods may also or alternatively include a number of sessions of cathodal tDCS at a confirmed electrode location and stimulus intensity to provide sustained tinnitus relief. Methods may also or alternatively include a number of maintenance sessions to prolong the sustained relief.
摘要翻译：根据本发明的系统提供了一种便于携带的非侵入性装置，其适于向大脑递送电刺激，例如治疗耳鸣。这种系统优选是被配置为向患者提供经颅直流电刺激（tDCS）的头戴式系统，其中至少部分地在其上的治疗可由患者自行施用。 tDCS是一种非侵入性的脑刺激方法来治疗可能提供显着缓解的耳鸣或其他神经系统症状。根据本发明的方法优选包括阳极tDCS的简短会话，以通过产生耳鸣强度的瞬时降低来帮助确定足够的电极位置和刺激强度。方法还可以或者可选地包括在确认的电极位置处的阴极tDCS的多次会话和刺激强度以提供持续的耳鸣缓解。方法还可以或者可选地包括多个维护会话以延长持续的缓解。

3. 发明申请

WO2011150377A2 WAVEFORM SHAPES FOR TREATING NEUROLOGICAL DISORDERS OPTIMIZED FOR ENERGY EFFICIENCY 审中-公开
标题翻译：用于治疗优化能量效能的神经病变波形
公开(公告)号：WO2011150377A2
公开(公告)日：2011-12-01
申请号：PCT/US2011/038416
申请日：2011-05-27
申请人： NDI MEDICAL, LLC , GRILL, Warren, M. , WONGSARNPIGOON, Amorn
发明人： GRILL, Warren, M. , WONGSARNPIGOON, Amorn
IPC分类号： A61N1/32
CPC分类号： A61N1/36146 , A61N1/0529 , A61N1/3606 , A61N1/36175
摘要： Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency.
摘要翻译：用于刺激神经组织的系统和方法应用由开发的遗传算法（GA）导出的刺激波形，其可以耦合到哺乳动物有髓轴突的细胞外刺激的计算模型。该波形针对能量效率进行了优化。

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